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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Structural and Functional Polymer Materials in Biomedicine

edited by

Cristina Nistor

submission deadline 20 Oct 2025 | 2 articles | Viewed by 2347 | Submission Open

Keywords: polymer chemistry; biodegradable polymers; responsive polymers; nanocomposites; tissue engineering; smart materials; drug delivery systems; molecular structure; material characterization; biocompatibility

(This special issue belongs to the Section Materials Science)

Metabolomics in Oncology

edited by

Susan Costantini

and Elena Di Gennaro

submission deadline 20 Oct 2025 | 1 articles | Viewed by 2342 | Submission Open

Keywords: metabolome; cancer; oncology; nuclear magnetic resonance; mass spectrometry

(This special issue belongs to the Section Molecular Oncology)

Molecular Breeding of Plants: From CRISPR/Cas9 to Transcriptomics and MABc

edited by

Kwon-Kyoo Kang

submission deadline 20 Oct 2025 | 1 articles | Viewed by 2327 | Submission Open

Keywords: CRISPR/Cas9; transcriptomics; marker-assisted breeding; genome editing; plant genetics; gene expression; plant genomics; quantitative trait loci (QTL); crop improvement

(This special issue belongs to the Section Molecular Plant Sciences)

Cutting-Edge Methods for Exploiting Bioactive Compounds in Biomasses: From the Plant Matrix to Molecular Function

edited by Chiara Magni

submission deadline 20 Oct 2025 | 2 articles | Viewed by 2240 | Submission Open

Keywords: plant matrix; agri-food biomasses; biochemistry; bioactive compounds

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Exploring the Molecular Basis of Cellular Responses to Microgravity-Induced Oxidative Stress

edited by

Caterina Morabito

and

Simone Guarnieri

submission deadline 20 Oct 2025 | 2 articles | Viewed by 2205 | Submission Open

Keywords: microgravity; reactive oxygen species (ROS); oxidative damage; cellular antioxidant systems; cell metabolism; cell responses; molecular pathways; simulated microgravity; protective countermeasures

(This special issue belongs to the Section Molecular Biology)

Macrophages and Inflammation

edited by

Julia Kzhyshkowska

submission deadline 20 Oct 2025 | 1 articles | Viewed by 2199 | Submission Open

Keywords: innate immunity; transcriptional programs; epigenetics; immunometabolism; receptors; scavenging; cytokines; ROS

(This special issue belongs to the Section Molecular Immunology)

Molecular Studies of Mutations Related to Neurodegenerative Diseases

edited by

Fernando Cardona

submission deadline 20 Oct 2025 | 2 articles | Viewed by 2165 | Submission Open

Keywords: SNPs; mutations; structural effects; transcriptional regulation; splicing; translational regulation; post-transcriptional regulation; post-translational regulation; haploinsufficiency; nonsense mediated decay; in silico analysis; experimental analysis; missense; nonsense; frameshift; epigenetics; non-coding; coding; function alteration; stability alteration

(This special issue belongs to the Section Molecular Neurobiology)

Roles of Mast Cells in Immune-Induced Diseases

edited by Paul L.A. Van Daele and Willem A. Dik

submission deadline 20 Oct 2025 | 1 articles | Viewed by 2154 | Submission Open

Keywords: mast cell; fibrosis; inflammation; autoinflammation; autoimmunity; transplantation; gastrointestinal; pulmonary; cytokines; MRGPRX2; rejection

(This special issue belongs to the Section Molecular Immunology)

Mitochondrial Metabolism Alterations in Health and Disease: 2nd Edition

edited by

Vincenza Dolce

Rosita Curcio

and

Graziantonio Lauria

submission deadline 20 Oct 2025 | 1 articles | Viewed by 2072 | Submission Open

Keywords: mitochondrial Metabolism; mitochondrial disorders; cellular processes; dysregulation organisms’ physiology

(This special issue belongs to the Section Biochemistry)

Cyclodextrins for Drug/iRNA Co-Delivery

edited by

Ivana Jarak

and

Ana Figueiras

submission deadline 20 Oct 2025 | 1 articles | Viewed by 2066 | Submission Open

Keywords: advanced therapies; antibody-based therapies; active and passive tumor targeting; cancer; conventional chemotherapy; immune system; immunotherapy; immunotoxicity; nanomedicine; nanoparticles; nanotoxicity; tumor immune microenvironment (TIME); tumor microenvironment (TME); cyclodextrins

(This special issue belongs to the Section Macromolecules)

Newer Pharmacological Treatment Concepts for Patients with Acute Coronary Syndrome

edited by

Dimitrios Patoulias

submission deadline 20 Oct 2025 | 2 articles | Viewed by 2066 | Submission Open

Keywords: acute coronary syndrome (ACS); molecular studies; antiplatelet; anticoagulant drugs; lipid-lowering therapies

(This special issue belongs to the Section Molecular Pharmacology)

Diabetes: From Molecular Basis to Therapy, 2nd Edition

edited by

Madalina Musat

submission deadline 20 Oct 2025 | 2 articles | Viewed by 2018 | Submission Open

Keywords: diabetes; obesity; autoimmunity; insulin resistance

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Bioactive Peptides: Synthesis, Functions, and Medicinal Chemistry Applications

edited by

Giovanni Grazioso

submission deadline 20 Oct 2025 | 3 articles | Viewed by 2015 | Submission Open

Keywords: peptides; protein– protein interactions (PPIs); peptide intracellular delivery

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Research on Osteogenesis

edited by

Roberto Sacco

and

Carlos Fernando Mourão

submission deadline 20 Oct 2025 | 1 articles | Viewed by 2007 | Submission Open

Keywords: osteogenesis; bone reconstruction; bone regeneration; bone disease

(This special issue belongs to the Section Molecular Biology)

Signaling in Respiratory Diseases

edited by Tonio Pera

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1999 | Submission Open

Keywords: asthma; COPD; cystic fibrosis; GPCR; pharmacology; inflammation; airway remodeling

(This special issue belongs to the Section Molecular Biology)

Predictors of Response to Cancer Immunotherapy

edited by

Stephanie J. Tuminello

and

Emanuela Taioli

submission deadline 20 Oct 2025 | 2 articles | Viewed by 1976 | Submission Open

Keywords: immunotherapy; immune checkpoint inhibitors; cancer; cancer therapy; precision medicine; survival outcomes

(This special issue belongs to the Section Molecular Immunology)

Neurodegenerative Disease: Looking for Oxidative Stress and Inflammation Mechanisms

edited by

Soraya L. Valles

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1942 | Submission Open

Keywords: neurodegenerative disease; oxidative stress; inflammation mechanisms; neurons; astrocytes; microglia; oligodendroglia

(This special issue belongs to the Section Molecular Neurobiology)

Research on Cyclodextrin

edited by Valentina Giglio

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1913 | Submission Open

Keywords: drug delivery systems; polymeric cyclodextrin; pollution removal; sponge-like material; selective targeting systems; catalyst

(This special issue belongs to the Section Materials Science)

Genomic Variation and Epidemiology of Cystic Fibrosis

edited by

Fernando Augusto Lima Marson

submission deadline 20 Oct 2025 | 2 articles | Viewed by 1909 | Submission Open

Keywords: CFTR; epidemiology; genetics; gene expression; personalized medicine; precision medicine

(This special issue belongs to the Section Molecular Genetics and Genomics)

Liposomes: Molecular Marvels in Drug Delivery

edited by

Parkson Lee-Gau Chong

and Juyang Huang

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1905 | Submission Open

Keywords: liposomal drug; targeted delivery; controlled release; hydrogen bonding; long-term stability; archaeosomes; cytotoxicity; lyophilized liposomal drugs

(This special issue belongs to the Section Molecular Biophysics)

Cancer Biomarkers and Metabolic Vulnerabilities

edited by Francesca Bersani

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1895 | Submission Open

Keywords: cancer metabolism; cancer biomarkers; liquid biopsy; therapeutic targets; metabolic rewiring

(This special issue belongs to the Section Biochemistry)

Physiological and Molecular Responses to Biotic and Abiotic Stressors in Marine Organisms

edited by

Chiara Lauritano

and Miriam Ruocco

submission deadline 20 Oct 2025 | 2 articles | Viewed by 1852 | Submission Open

Keywords: stress responses; marine organisms; enzymatic pathways; multiple stressors; stress markers; epigenetic response; physiological response

(This special issue belongs to the Section Molecular Biology)

Virus Engineering and Applications: 3rd Edition

edited by

Laura Menotti

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1845 | Submission Open

Keywords: virus engineering; oncolytic virotherapy; immunovirotherapy; viral biotechnology

(This special issue belongs to the Section Molecular Microbiology)

Interplay Between the Human Microbiome and Diseases

edited by

Tihamer Molnar

and

Zoltán Péterfi

submission deadline 20 Oct 2025 | 2 articles | Viewed by 1833 | Submission Open

Keywords: microbiome; metagenome; gastrointestinal tract; skin; seminal fluid; lung; saliva; oral mucosa; conjunctiva; dysbiosis; fecal microbiota transplantation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Latest Advances in Cytokine Storm

edited by

Raymond Kaempfer

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1787 | Submission Open

Keywords: cytokine storm; cytokine release syndrome; inflammatory; protective immunity; multi-drug resistant bacterial strains

(This special issue belongs to the Section Molecular Immunology)

Diagnosis and Treatment of Osteoporosis

edited by

Fabio Vescini

submission deadline 20 Oct 2025 | 2 articles | Viewed by 1782 | Submission Open

Keywords: osteoporosis; diagnosis; dual X-rays absorptiometry; DXA; bone turnover markers; secondary osteoporosis; therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Research on Drug Metabolism and Disposition

edited by Tashinga E. Bapiro

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1768 | Submission Open

Keywords: drug metabolism; metabolite identification; biotransformation; clearance; bioavailability; pharmacokinetics; absorption; dose prediction; reaction phenotyping

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Applications of Technologies and Techniques for the Extraction of Simple Molecules and Compounds

edited by

Kiril Gavazov

submission deadline 20 Oct 2025 | 3 articles | Viewed by 1732 | Submission Open

Keywords: sample preparation; natural product extraction; purification; pollutant extraction; nutraceutical extraction; extraction of environmental indicators; magnetic extraction; green analytical chemistry; liquid– liquid (micro)extraction; cloud point (micro)extraction; solid phase (micro)extraction; pressurized liquid extraction; ultrasound-assisted extraction; microwave-assisted extraction; deep eutectic solvents; supercritical fluid extraction; molecularly imprinted polymers; QuEChERS (quick; easy; cheap; effective; rugged and safe)

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Extraction, Identification and Quantification of Bioactive Molecules

edited by

Francesca Scionti

and Rosario Mare

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1712 | Submission Open

Keywords: extracts; botanicals; nutraceuticals; bioactive molecules; spectrometry; spectrophotometer; chromatography; western blotting; molecular mechanisms

(This special issue belongs to the Section Molecular Biology)

Molecular Advances in the Synthesis and Medical Application of Biomaterials

edited by

Csaba Balázsi

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1705 | Submission Open

Keywords: nanostructured biomaterials; bioceramics; bioactive; biodegradable; resorbable materials; biomimetic materials; biocompatibility

(This special issue belongs to the Section Materials Science)

Liver Fibrosis: Molecular Pathogenesis, Diagnosis and Treatment

edited by Manuel Morales-Ruiz

submission deadline 20 Oct 2025 | 2 articles | Viewed by 1694 | Submission Open

Keywords: liver fibrosis; cirrhosis; hepatic stellate cells; collagen; fibrogenic pathways; diagnosis of fibrosis; therapeutic strategies for liver disease; extracellular matrix remodeling; cell-to-cell interactions; fibrosis complications

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Microbiome and Metabolome in the Gastrointestinal Tract, 3rd Edition

edited by

Ioannis Alexandros Charitos

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1693 | Submission Open

Keywords: microbiome; dysbiosis; microbiology; immunity; cytokine/chemokine networks; microbiota axes pathways; toxic substances; autoimmunity

(This special issue belongs to the Section Molecular Biology)

Non-Coding RNA: Biomarkers for Cardiovascular Diseases

edited by

Isabel Moscoso

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1691 | Submission Open

Keywords: cardiovascular diseases; non-coding RNA (ncRNA); therapeutics; biomarkers; microRNA; lncRNA; siRNA

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Processes and Applications of Plasma in Liquids

edited by

Ricardo Molina

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1680 | Submission Open

Keywords: plasma in liquids; water decontamination; plasma-activated water; hydrogels; plasma medicine; polymerization in liquids; plasma agriculture

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Molecular Research on Neuroinflammation and Brain Aging

edited by

Stephen C. Bondy

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1673 | Submission Open

Keywords: neurotoxicology; aging; Alzheimer's disease; neurodegenerative diseases; inflammatory

(This special issue belongs to the Section Molecular Toxicology)

Molecular Advances in Analytical Techniques for Biological and Medical Research: 2nd Edition

edited by

Angela Di Capua

and

Maria Assunta Acquavia

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1668 | Submission Open

Keywords: HPLC; GC; electrophoresis; mass spectrometry; plant materials; validation; metabolomics; proteomics; protein– ligand interaction.

(This special issue belongs to the Section Molecular Biology)

Bioactive Food Compounds in the Prevention and Treatment of Non-Communicable Diseases

edited by

Aneta Kopeć

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1653 | Submission Open

Keywords: bioactive compounds; dietary fiber; polyphenols; sulfur compounds; antioxidant; reduce oxidative stress; inflammation; non-communicable diseases

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Advances in Seed Development and Germination

edited by

Sławomir Borek

Łukasz Wojtyla

and

Małgorzata Garnczarska

submission deadline 20 Oct 2025 | 2 articles | Viewed by 1640 | Submission Open

Keywords: seed aging; seed development; seed dormancy; seed germination; seed metabolism; seed preservation; seed priming; seed responses to stress

(This special issue belongs to the Section Molecular Plant Sciences)

Perspectives of Molecular Genetics and Genomics in Human Mendelian Diseases

edited by

Marta Rusmini

submission deadline 20 Oct 2025 | 2 articles | Viewed by 1616 | Submission Open

Keywords: functional genomics; omics; genetic disease; human; molecular mechanisms; genome editing; biomarkers; computational genomics

(This special issue belongs to the Section Molecular Genetics and Genomics)

Latest Advances in Protein-Ligand Interactions

edited by

Fabio Altieri

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1589 | Submission Open

Keywords: protein– ligand interaction; molecular mode of actions; target identification; drug discovery; bioactive agents

(This special issue belongs to the Section Molecular Pharmacology)

Advancing Occupational Health Through Omics Technologies

edited by

Silvia Vivarelli

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1586 | Submission Open

Keywords: omics technologies; occupational health; biomarkers; personalized risk assessment; workplace exposures; genomics; proteomics; psychosocial factors; disease susceptibility; preventive medicine

(This special issue belongs to the Section Molecular Biology)

Mechanism and Treatment Progress of Liver Disease

edited by Yohei Shirakami

submission deadline 20 Oct 2025 | 3 articles | Viewed by 1580 | Submission Open

Keywords: liver diseases; MASLD; alcoholic liver disease; liver cancer; viral hepatitis; sarcopenia

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Gynecologic Oncology: Molecular Mechanisms and Therapies

edited by

Angel Yordanov

submission deadline 20 Oct 2025 | 3 articles | Viewed by 1557 | Submission Open

Keywords: cervical cancer; endometrial cancer; ovarian cancer; vulvar cancer; carcinogenesis; microinvairment; immunotherapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Host Responses to Virus Infection

edited by Hideki Hayashi and Yoshinao Kubo

submission deadline 20 Oct 2025 | 2 articles | Viewed by 1554 | Submission Open

Keywords: viral infection; host reactions; interferon alpha and beta; interferon gamma; cytokines; vaccine; cytokine storm

(This special issue belongs to the Section Molecular Microbiology)

Latest Advances in Comparative Genomics

edited by

Candice Brinkmeyer-Langford

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1542 | Submission Open

Keywords: genetics; genomics; evolution; phylogeny; sequencing; variation; conservation

(This special issue belongs to the Section Molecular Informatics)

Computer Analysis for Molecular Pathological Research

edited by

Luca Zammataro

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1527 | Submission Open

Keywords: machine learning; artifical intelligence; large language models; pathology; digital pathology; multimodal learning

(This special issue belongs to the Section Molecular Informatics)

Virus-Host Interplay: Mechanisms and Novel Therapeutic Strategies

edited by

Jinsung Yang

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1514 | Submission Open

Keywords: virus; autophagy; therapeutics; virus– host interaction; virus– receptor interaction; signaling

(This special issue belongs to the Section Molecular Biology)

Lymphedema: From Mechanism to Treatment

edited by

Florent Morfoisse

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1456 | Submission Open

Keywords: lymphedema; lymphatic dysfunction; molecular mechanisms; cell signaling; diagnostic imaging; biomarkers; therapeutic interventions; inflammation; adipose tissue accumulation; fibrosis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Pathogenesis, Biomarkers and Therapeutic Perspectives of Ocular Diseases

edited by

Eugenia Piragine

submission deadline 20 Oct 2025 | 2 articles | Viewed by 1386 | Submission Open

Keywords: ocular diseases; dry eye; glaucoma; diabetic retinopathy; macular degeneration; molecular mechanisms; diagnosis; preclinical research; clinical studies; drug therapy; pharmacology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Dietary Nitrate and Metabolic Health

edited by

Jun Kobayashi

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1372 | Submission Open

Keywords: nitric oxide (NO); dietary nitrate; metabolic health; s-nitroso compound; NO bioavailability

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Displaying special issue 2751-2800 on page 56 of 70.

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