Virus-Host Interplay: Mechanisms and Novel Therapeutic Strategies
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 20 October 2025 | Viewed by 1596
Special Issue Editor
Interests: virus–host interaction; ligand–receptor interactions; signal transduction
Special Issue Information
Dear Colleagues,
In recent years, the interactions between viruses and their hosts have become a focal point of research, with them providing critical insights into viral infection mechanisms, host responses, and potential therapeutic approaches. The following Special Issue, Virus–Host Interplay: Mechanisms and Novel Therapeutic Strategies, presents cutting-edge research that elucidates the complex molecular interactions that occur during viral infections. Moreover, it highlights the defensive responses of host organisms and the sophisticated evasion strategies of viruses.
The complex interplay between viruses and their host cells governs the infection mechanism. While viruses exploit the host cell machinery for replication, the host activates immune defenses to limit viral spread and damage. These interactions extend beyond direct molecular contact and involve modulation of signaling pathways, metabolic reprogramming, and immune response regulation. Dissecting these processes deepens our understanding of the underlying biology and unveils new targets for innovative therapies.
In this issue, we combine insights from virology, immunology, cell biology, and computational modeling to address the interactions between hosts and a range of viral pathogens. We introduce and discuss novel therapeutic strategies, from antiviral drug development to host-targeted therapies aimed at augmenting immune responses or suppressing viral mechanisms of host manipulation. We aim to expand the boundaries of current knowledge in virus–host interactions. We hope that this collection will open new research directions and help in the development of effective antiviral therapies.
Dr. Jinsung Yang
Guest Editor
Manuscript Submission Information
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Keywords
- virus
- autophagy
- therapeutics
- virus–host interaction
- virus–receptor interaction
- signaling
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