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Dietary Nitrate and Metabolic Health

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".

Deadline for manuscript submissions: 31 August 2024 | Viewed by 220

Special Issue Editor

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Guest Editor
Department of Clinical Dietetics and Human Nutrition, Faculty of Pharmaceutical Science, Josai University, 1-1 Keyakidai, Sakado 350-0295, Japan
Interests: nitric oxide; nitrate/nitrite; crush syndrome; ischemia/reperfusion injury; reactive oxygen species
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Special Issue Information

Dear Colleagues,

Nitric oxide (NO) is endogenously generated from L-arginine and oxygen by NO synthases. In addition, inorganic nitrate from dietary sources generates NO and nitrosating agents, such as the S-nitroso compound, in the acidic stomach, thus providing local and systemic NO bioactivities. Recent evidence suggests that local and systemic NO bioavailability is associated with health maintenance through the nitrate–nitrite–NO pathway, and it is affected by many habitual and physiological factors, including dietary habits, oral commensal bacteria, gastric acidity, intestinal bacterial flora, and thiol-containing food and drugs. Therefore, it is important to discuss the association between diet, including dietary nitrate, and metabolic health from biological and physiological standpoints. Although dietary nitrate provides beneficial effects, it is a source of carcinogenic N-nitroso compounds under certain physiological conditions. Thus, this Special Issue also welcomes studies dealing with controversial findings. I look forward to fruitful discussions regarding dietary nitrate and metabolic health in this Special Issue. I welcome submissions of both original articles and reviews that will offer the readers of IJMS new findings and comprehensive explanations on dietary nitrate and metabolic health. These are necessary for the development of novel research approaches, particularly those related to health maintenance strategies.

Prof. Dr. Jun Kobayashi
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • nitric oxide (NO)
  • dietary nitrate
  • metabolic health
  • s-nitroso compound
  • NO bioavailability

Published Papers

This special issue is now open for submission.
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