Metal Complexes: From Synthesis to Pharmacological Studies and Application
A Special Issue of International Journal of Molecular Sciences (ISSN 1422-0067) belonging to the section "Molecular Pharmacology".
Deadline for manuscript submissions: 31 October 2026 | Viewed by 306
Editors
Interests: medicinal chemistry; organic chemistry; pharmaceutics
Special Issue Information
Dear Colleagues,
Metal complexes have emerged as an important class of compounds in medicinal chemistry due to their unique structural diversity, tunable physicochemical properties, and broad spectrum of biological activities. In recent decades, coordination compounds of transition metals have attracted considerable attention as potential therapeutic agents, particularly in the development of anticancer, antimicrobial, antiviral, and anti-inflammatory drugs. Advances in synthetic methodologies, structural characterization techniques, and biological evaluation have significantly expanded our understanding of the relationship between coordination chemistry and pharmacological activity.
This Special Issue aims to bring together high-quality contributions addressing the synthesis, structural characterization, and biological investigation of metal complexes with pharmacological potential. Particular emphasis will be placed on studies exploring ligand design, coordination environments, structure–activity relationships, and the mechanisms underlying the biological effects of metal-based compounds.
We encourage the submission of original research articles as well as review papers covering experimental and theoretical approaches to the development of bioactive metal complexes. Studies involving biomolecular interactions, molecular docking, computational modeling, and in vitro or in vivo pharmacological investigations are also welcome.
Topics include, but are not limited to, the following:
- Design and synthesis of bioactive metal complexes
- Coordination chemistry of pharmacologically relevant ligands
- Structure–activity relationships in metal-based therapeutics
- Biomolecular interactions of metal complexes (DNA, proteins, enzymes)
- Molecular docking and computational studies of metal-based drugs
- Anticancer, antimicrobial, antiviral, and anti-inflammatory metal complexes
- Mechanistic studies of metal-mediated biological activity
- Advances in medicinal inorganic and bioinorganic chemistry
Dr. Joksimović Nenad
Guest Editor
Dr. Snežana Stojanović
Guest Editor Assistant
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- metal complexes
- medicinal inorganic chemistry
- bioactive ligands
- pharmacological activity
- molecular docking
- biomolecular interactions
- anticancer agents
- antimicrobial activity
- coordination chemistry
- structure–activity relationship
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