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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Recent Advances in Retinal Neurobiology

edited by

Tamas Kovacs-Oller

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1601 | Submission Open

Keywords: retina; vision; disease; ganglion cells; amacrine cells; bipolar cells; horizontal cells; photoreceptors; astrocytes; microglia; Mü ller cells

(This special issue belongs to the Section Molecular Neurobiology)

The Molecular Role of Platelets in Human Diseases

edited by

Lukasz Szarpak

and

Michał Pruc

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1584 | Submission Open

Keywords: platelet; biomarkers; platelet membrane proteins; platelet-derived microparticles; platelet-related diseases; thrombosis; inflammatory diseases; cardiovascular disease; cancer; tumor growth and metastasis

(This special issue belongs to the Section Molecular Biology)

Scleroderma: From Biomarkers to Therapeutic Targets

edited by Kathryn Seraphin Torok

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1547 | Submission Open

Keywords: scleroderma; biomarkers; epigenetics; RNA sequencing; genetics and genomics; therapeutic targets

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Chronic Liver Disease and Hepatocellular Carcinoma—2nd Edition

edited by

Daniela Gabbia

and Sara Carpi

submission deadline 20 Sep 2025 | 2 articles | Viewed by 1545 | Submission Open

Keywords: hepatocellular carcinoma; NAFLD/NASH; viral hepatitis; autoimmune liver disease; immunotherapy; biomarker

(This special issue belongs to the Section Molecular Oncology)

New Research in Spatial Proteomics

edited by

Andrew Smith

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1533 | Submission Open

Keywords: spatial proteomics; mass spectrometry imaging; mass cytometry; biomarker; machine learning; spatial biology; molecular pathology; cancer

(This special issue belongs to the Section Molecular Informatics)

Advances in Burn Wound Healing and Skin Regeneration: Innovations and Insights

edited by

H. Ibrahim Korkmaz

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1528 | Submission Open

Keywords: burn wound healing; skin regeneration; novel biomaterials; wound dressings; regenerative therapies

(This special issue belongs to the Section Biochemistry)

New Advances in the Field of Thrombosis and Hemostasis

edited by

Claudia Maria Radu

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1514 | Submission Open

Keywords: bleeding; thrombosis; new diagnostic tests; rare diseases; platelet function; biomarkers; risk factors; thrombocytopenia; endothelial dysfunction; autoantibodies; extracellular vesicles; stem cells; gene therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Advances in Forensic Toxicology: Innovative Approaches in Detection of New Psychoactive Substances

edited by Roberta Tittarelli and Giulio Mannocchi

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1501 | Submission Open

Keywords: addiction; new psychoactive substances; mass spectrometry; biological matrices; diversion; forensic toxicology; drug testing

(This special issue belongs to the Section Molecular Toxicology)

Reproductive Diseases and Modern Lifestyle: From Bench to Bedside

edited by

Georgios Valsamakis

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1491 | Submission Open

Keywords: infertility; endocrine disrupting chemicals; reproductive hormones; lifestyle; metabolic diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Genetic Prediction of Risk of Common Diseases

edited by

Grant Morahan

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1469 | Submission Open

Keywords: complex genetic diseases; cancer; heart disease; diabetes; dementia; polygenic risk score; genetic risk signatures

(This special issue belongs to the Section Molecular Genetics and Genomics)

Pathophysiology and New Therapies of Alopecia

edited by Jong-Hyuk Sung

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1459 | Submission Open

Keywords: alopecia; pathophysiology; novel pharmacological treatments; regenerative medicines; gene therapy; cell therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Dynamics Simulation of Biomolecules

edited by

Pavel Rehak

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1441 | Submission Open

Keywords: molecular dynamics simulations; biochemical processes; biomaterial properties

(This special issue belongs to the Section Molecular Biophysics)

Characterization and Biological Functions of Plant Extracts

edited by

Muna Ali Abdalla

and

Lyndy McGaw

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1429 | Submission Open

Keywords: biological activity of plant-derived products; antimicrobial activity; in vitro antibiofilm activity; anticancer activity; anti-inflammatory activity; secondary metabolites

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Amyotrophic Lateral Sclerosis Behind Motor Neurons

edited by

Patrizia Longone

and Ezia Guatteo

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1428 | Submission Open

Keywords: non-neuronal cells; neurotransmitters; systemic disease; motor system; neuronal circuitry; skeletal muscle metabolism; muscle oxidative metabolism

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Advances in Omics in Agriculture

edited by

Sebastian Wojciech Przemieniecki

submission deadline 20 Sep 2025 | 2 articles | Viewed by 1426 | Submission Open

Keywords: agronomy; plant production; animal production; genome; microbiome; metagenomics; RNAseq; molecular mechnisms; molecular pest diagnostics; molecular interactions; gene editing

(This special issue belongs to the Section Molecular Informatics)

Phytochemical Dynamics: Plant Metabolite Responses to Environmental Factors

edited by

Ivana Sola

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1391 | Submission Open

Keywords: plant metabolites; phytochemicals; biotic and abiotic factors; environmental influences; biochemical pathways; interactions

(This special issue belongs to the Section Molecular Plant Sciences)

Reproductive Genetics and Epigenetics: Insights into Infertility Failures and Treatment Pathways

edited by

Hossam H. Shawki

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1377 | Submission Open

Keywords: infertility; epigenetics; polymorphism; gametogenesis; fertilization; embryo development; reproductive organs; congenital malformations

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Mechanism and Therapeutic Approaches of Breast Cancer, Metastatic Breast Cancer, 3rd Edition

edited by

Mi Kyung Park

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1331 | Submission Open

Keywords: breast cancer; metastatic breast cancer; epithelial-to-mesenchymal transition (EMT); epigenetic and post-translational modifications (PTM); tumor microenvironment

(This special issue belongs to the Section Molecular Oncology)

Investigation of Natural Products as Sources of Bioactive Molecules, 2nd Edition

edited by

Stefania Garzoli

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1320 | Submission Open

Keywords: metabolomic; secondary metabolites; phytochemical analysis; bioactivity; chemical investigation

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Advances and Current Challenges in Plasma Medicine

edited by

Andrei Vasile Nastuta

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1317 | Submission Open

Keywords: plasma medicine; plasma pharmacology; plasma oncology; plasma bioengineering; plasma agronomy; plasma and food; plasma and automotive; plasma and aerospace; plasma diagnostics; plasma material processing; plasma polymerization and coating; simulation of plasma phenomena during interaction with matter

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Glutamatergic Signaling in the Nervous System

edited by

Osama Abulseoud

and

Frank Schmitz

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1302 | Submission Open

Keywords: glutamate glutamine cycle; neurotoxicty; ferroptosis; hyperglutamatergic states; innovative pharmacological interventions

(This special issue belongs to the Section Molecular Neurobiology)

Chemistry Triggered by Low-Energy Particles

edited by Hassan Abdoul-Carime

submission deadline 20 Sep 2025 | 2 articles | Viewed by 1299 | Submission Open

Keywords: low energy (< 50 eV); photons; electrons; ions; gas phase; single molecules; clusters; condensed phase liquids and films; experimental techniques; density functional theory; IA-based prediction models

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Drug-Induced Neurotoxicity and Neurodegeneration: Mechanisms, Models and Implications

edited by

Daniel José Barbosa

and

Renata Silva

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1276 | Submission Open

Keywords: drugs of abuse; pharmaceutical drugs; environmental toxins; drug exposure; neurotoxicity; neurodegeneration; brain health; substance use disorders; therapeutic interventions; in vivo models; in vitro models; in silico models; biomarkers of damage; translational studies

(This special issue belongs to the Section Molecular Neurobiology)

Hybrid Organic–Inorganic Materials: From Synthesis to Applications

edited by

Mirta Rubčić

and

Višnja Vrdoljak

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1242 | Submission Open

Keywords: hybrid; organic– inorganic; functional materials; structure– property; design; synthesis

(This special issue belongs to the Section Materials Science)

Cell Fate Decisions: Autophagy, Apoptosis, Pyroptosis, Necroptosis, Ferroptosis and PANoptosis in Health and Disease

edited by

Yaqiu Wang

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1218 | Submission Open

Keywords: inflammation; autophagy; apoptosis; pyroptosis; necroptosis; PANoptosis; ferroptosis; cell death; cell survival

(This special issue belongs to the Section Molecular Biology)

Molecular Research on Type 1 Diabetes and Its Complications: 2nd Edition

edited by

Jolanta Neubauer-Geryk

submission deadline 20 Sep 2025 | 2 articles | Viewed by 1215 | Submission Open

Keywords: type 1 diabetes mellitus; diabetic microangiopathy; diabetic macroangiopathy; continuous glucose monitoring; experimental diabetic models; biomarkers; endothelium dysfunction; diabetes-related diseases; comorbidities; pregnancy; pathophysiology; metabolic syndrome; treatment; precision medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Advances in Electrochemical Materials

edited by

Raj Karthik

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1203 | Submission Open

Keywords: electrochemical materials; molecular design; energy storage; electrocatalysis; sensing applications; nanomaterials; sustainable materials; hybrid systems; interface engineering; green chemistry

(This special issue belongs to the Section Materials Science)

Unraveling the Genetic Background of Neurological Disorders: 2nd Edition

edited by

Vasileios Siokas

Efthimios Dardiotis

and

Ioannis Liampas

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1192 | Submission Open

Keywords: neurological disorders; neurogenetics; personalized treatments; gene-association studies; genetics; genome-wide association studies; genetic linkage studies

(This special issue belongs to the Section Molecular Genetics and Genomics)

Mitochondria as a Therapeutic Target for Anti-Cancer Drugs

edited by

Dalia Marija Kopustinskiene

submission deadline 20 Sep 2025 | Viewed by 1180 | Submission Open

Keywords: mitochondria; cancer; apoptosis; oxidative phosphorylation; Warburg effect; cardiolipin; inflammation

(This special issue belongs to the Section Molecular Oncology)

Type 1 Diabetes: Molecular Mechanisms and Therapeutic Approach

edited by Preeti Chhabra

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1143 | Submission Open

Keywords: type 1 diabetes; microbiome; proteomics; immunotherapy; β -cell replacement; single-cell sequencing; stem cells; gene editing technologies; tolerance

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Novel Nanoparticle Composites: Functionalization and Application

edited by

Jovan M. Nedeljković

and

Vesna Lazić

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1139 | Submission Open

Keywords: nanoparticles; nanocomposites; synthesis; functionalization; interface; photocatalysis; antimicrobial nanoparticles; nanomedicine; theoretical modelling; computer simulations

(This special issue belongs to the Section Molecular Nanoscience)

The Role of Lipids in Human Health

edited by

Angela Maria Rizzo

and Irma Colombo

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1113 | Submission Open

Keywords: lipids; lipidomics; fatty acids; sphingolipids; steroids; metabolism

(This special issue belongs to the Section Biochemistry)

The Blood–Brain Barrier and Neuroprotection

edited by Aruna Sharma and Hari Shanker Sharma

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1113 | Submission Open

Keywords: blood– brain barrier; neurodegenerative diseases; nanoformulations; drug development; delivery systems

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Research on Tumor Metastasis and Inhibition

edited by

Yu-Chan Chang

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1105 | Submission Open

Keywords: metastasis; epithelial– mesenchymal transition; small-molecule compounds; animal imaging; signal transduction

(This special issue belongs to the Section Molecular Oncology)

Human Hereditary Diseases: Advances in Molecular Genetics, Genomics and Therapeutic Strategies

edited by Yulin Jin and

Yujing Li

submission deadline 20 Sep 2025 | 2 articles | Viewed by 1086 | Submission Open

Keywords: hereditary diseases; genetics and genomics; molecular mechanism; gene regulation; therapeutic approach

(This special issue belongs to the Section Molecular Genetics and Genomics)

Advances in Diabetic Ischemic Heart Failure

edited by Branko Beleslin

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1049 | Submission Open

Keywords: diabetes; ischemic cardiomyopathy; pathophysiology; diagnostics; therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Molecular Therapeutics for HIV Co-Infections

edited by

Vishwanath Venketaraman

and

Selvakumar Subbian

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1042 | Submission Open

Keywords: HIV co-infections; molecular therapeutics; Mtb; ART; immune responses

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Research of Natural Products in Cancer Diseases

edited by

Angeliki Tiptiri-Kourpeti

submission deadline 20 Sep 2025 | Viewed by 1033 | Submission Open

Keywords: cancer; natural products; drug resistance; side effects; bioactive compounds; prevention; treatment; signaling pathways; tumor microenvironment

(This special issue belongs to the Section Molecular Oncology)

Gestational Diabetes Mellitus: Molecular Insights into Pathophysiology, Management and Therapy

edited by

Paweł Jan Stanirowski

submission deadline 20 Sep 2025 | 2 articles | Viewed by 1006 | Submission Open

Keywords: GDM pathogenesis; health programming; pharmacogenomics; life-style interventions; fetal growth disorders; preeclampsia; polyhydramnios; placental origin of disease

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Diagnosis and Targeted Therapies in Ischemic Stroke

edited by Alicia Aliena-Valero and María Castelló-Ruiz

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1001 | Submission Open

Keywords: ischemic stroke; cerebral protection; repair treatments; therapeutic approaches

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Multifunctional Nanocomposites for Bioapplications

edited by

Athina Angelopoulou

submission deadline 20 Sep 2025 | 2 articles | Viewed by 986 | Submission Open

Keywords: nanocomposites; biomedical applications; molecular characteristics; metabolic pathways; biomarkers; external stimuli

(This special issue belongs to the Section Molecular Nanoscience)

Bioconjugates and Application

edited by

Gábor Mező

submission deadline 20 Sep 2025 | 1 articles | Viewed by 939 | Submission Open

Keywords: bioconjugates; targeted therapy; homing moieties; drug delivery; bioconjugates as diagnostic tools; targeted nanoparticles; antibody– drug conjugates; linkage systems

(This special issue belongs to the Section Macromolecules)

Intestinal Microbiome and Its Function

edited by

Simone Baldi

submission deadline 20 Sep 2025 | 1 articles | Viewed by 927 | Submission Open

Keywords: human microbiome; gut microbiome; microbiota-derived metabolites; SCFAs; gut– organ axis

(This special issue belongs to the Section Molecular Microbiology)

Personalized Nanomedicine in Oncology

edited by Sajid Ali

submission deadline 20 Sep 2025 | Viewed by 922 | Submission Open

Keywords: drug/gene delivery; biomaterials; stimuli-responsive systems; lipid– polymer nanoparticles; lipodendriplexes; dual delivery; inorganic nanoparticles; targeted delivery system

(This special issue belongs to the Section Molecular Nanoscience)

Novel Insights into Reproductive Toxicology

edited by Maria Cristina Budani

submission deadline 20 Sep 2025 | 1 articles | Viewed by 915 | Submission Open

Keywords: endocrine disruptors; environmental toxicants; fertility; heavy metals; lifestyle habits; molecular mechanisms; pregnancy; teratology; teratogenic compounds; reproductive toxicology

(This special issue belongs to the Section Molecular Toxicology)

Peripheral Neuropathies: Molecular Research and Novel Therapy—2nd Edition

edited by

Zhidong Zhou

submission deadline 20 Sep 2025 | 1 articles | Viewed by 890 | Submission Open

Keywords: axonal degeneration; demyelination; schwann cells; dorsal root ganglia; diabetic neuropathy; chemotherapy-induced peripheral neuropathies; immune-mediated neuropathies; immune checkpoint inhibitors; charcot-marie-tooth disease; autonomic neuropathies

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Research on Apoptosis and Autophagy in Osteosarcoma

edited by

Hyung-Mun Yun

and

Kyung-Ran Park

submission deadline 20 Sep 2025 | 1 articles | Viewed by 888 | Submission Open

Keywords: apoptosis; autophagy; bioactive molecule; cancer; necroptosis; osteosarcoma; osteoclast; osteoblast

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

New Advances in Glioma Knowledge: From Genome to Signal Pathways Alterations

edited by

Sabrina Di Bartolomeo

and Giuseppina D'Alessandro

submission deadline 20 Sep 2025 | 1 articles | Viewed by 882 | Submission Open

Keywords: gliomas; signalling pathways; genetic alterations; epigenetics; metabolic alterations; drug resistance; glioma stem cells

(This special issue belongs to the Section Molecular Neurobiology)

Mitochondria and Energy Metabolism Reprogramming in Diseases

edited by

Nadège Bellance

submission deadline 20 Sep 2025 | 1 articles | Viewed by 860 | Submission Open

Keywords: mitochondrial dysfunctions; energy metabolism; pathophysiological mechanisms; therapeutic targets; physiology of organelle

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Role of the Endocannabinoid System in Reward- and Addiction-Related Neuroplasticity

edited by

Francisco Navarrete-Rueda

and

María S. García Gutiérrez

submission deadline 20 Sep 2025 | 1 articles | Viewed by 830 | Submission Open

Keywords: endocannabinoid system; neuroplasticity; reward; addiction; biomarker; therapeutic approach

(This special issue belongs to the Section Molecular Neurobiology)

Displaying special issue 1401-1450 on page 29 of 68.

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