Submit to IJMS Review for IJMS Propose a Special Issue

Journal Menu

Journal Browser

Special Issues

International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

Section

Search by Title/Keyword

Order results

Display

Results per page

Alzheimer’s Disease: Molecular Mechanisms and Novel Therapies

edited by Noah R. Johnson and

Chih Hung Lo

submission deadline 20 Nov 2026 | 3 articles | Viewed by 2127 | Submission Open

Keywords: intrinsically disordered proteins; apolipoproteins; neuroinflammation and neuroimmune; autolysosomal and mitochondrial functions; lipid metabolism; blood-brain barrier; biosensors; nanomedicine; high-throughput screening; therapeutic discovery

(This special issue belongs to the Section Molecular Neurobiology)

Current Research on Autophagy in Aging and Age Related Diseases

edited by

Tímea Sigmond

submission deadline 20 Nov 2026 | 2 articles | Viewed by 2020 | Submission Open

Keywords: autophagy; aging; molecular mechanisms; age related diseases; mitochondria

(This special issue belongs to the Section Biochemistry)

Recent Progress in Synthesis, Properties, and Applications of Polyoxometalates and Their Nanocrystals

edited by

Xiang Ma

and

Pengtao Ma

submission deadline 20 Nov 2026 | 1 articles | Viewed by 1874 | Submission Open

Keywords: polyoxometalates; POMs; metal cluster compound; inorganic chemistry; nanocrystals

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Plant Responses to Abiotic and Biotic Stresses: 2nd Editon

edited by

Longxing Tao

and

Tingting Chen

submission deadline 20 Nov 2026 | 1 articles | Viewed by 1717 | Submission Open

Keywords: climate change and crop production; abiotic stress; biotic stress; plant resistance to abiotic and biotic stresses; molecular mechanism; physiological responses; plant hormones; carbohydrate metabolism and transport; molecular signaling; reactive oxygen species (ROS); calcium ions; photosynthesis; respiration; energy metabolism

(This special issue belongs to the Section Molecular Plant Sciences)

Responses of Plants to Abiotic and Biotic Stresses: Concepts and Mechanisms

edited by

Ning Liu

submission deadline 20 Nov 2026 | 2 articles | Viewed by 1608 | Submission Open

Keywords: plant stress tolerance; abiotic stresses; biotic stresses; molecular mechanisms; signal pathways; multi-omics technologies; epigenetic modifications; crop resilience

(This special issue belongs to the Section Molecular Plant Sciences)

Marine Natural Products as a Source of Therapeutics—Recent Trends

edited by

Komal Anjum

submission deadline 20 Nov 2026 | 1 articles | Viewed by 1540 | Submission Open

Keywords: marine natural products; marine-associated microbes; antimicrobial drug; antibiotics; marine-derived peptides; anti-inflammatory; molecular pharmacology; targeted therapies; extraction

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Advances in Sepsis: Molecular and Biochemical Perspectives

edited by

Akrivi Chrysanthopoulou

submission deadline 20 Nov 2026 | 1 articles | Viewed by 1401 | Submission Open

Keywords: sepsis; outcome; molecular diagnosis; machine learning; biochemical biomarkers; targeted immunotherapy; personalized medicine; sepsis inflammatory endotypes

(This special issue belongs to the Section Biochemistry)

Radiobiology: New Challenges and Advances

edited by

Lorenzo Manti

and

Pavel Bláha

submission deadline 20 Nov 2026 | 1 articles | Viewed by 1354 | Submission Open

Keywords: strategies for overcoming cancer radioresistance and normal-tissue damage mitigation; combined approaches: BNCT, proton–boron capture therapy, radioimmunotherapy; emerging technologies and novel temporal regimes: FLASH RT mechanisms and radiobiology of laser-accelerated particles; radiobiology of new ions and of novel dose-delivery modalities in particle radiotherapy; limphopoenia in radiotherapy and biomarkers of radiation response; three-dimensional models; microdosimetry: standardising measurements; DNA damage/repair; tumour microenvironment: autophagy, ferroptosis, fibroblast activation protein; non-cancer effects and non-targeted effects

(This special issue belongs to the Section Molecular Biology)

Molecular Pathogenesis and Treatment Approaches of Hematological Malignancies

edited by

Yosuke Minami

submission deadline 20 Nov 2026 | 1 articles | Viewed by 1153 | Submission Open

Keywords: leukemia; lymphoma; minimal residual disease (MRD); cancer genomic profiling (CGP); molecular targeted therapy

(This special issue belongs to the Section Molecular Oncology)

Biophysical Studies of Protein Structure-Function Relationships

edited by

Almerinda Di Venere

Giampiero Mei

and Velia Minicozzi

submission deadline 20 Nov 2026 | 1 articles | Viewed by 1056 | Submission Open

Keywords: protein structure; molecular dynamics; computational modeling; drug discovery

(This special issue belongs to the Section Molecular Biophysics)

Metal-Organic Frameworks: Pioneering New Solutions for Biomedical Challenges

edited by

David Rodríguez-Lucena

and

Belén Begines

submission deadline 20 Nov 2026 | 1 articles | Viewed by 945 | Submission Open

Keywords: MOFs; biomedical advances; drug delivery; personalized medicine; biomedical imaging; bio-sensor; smart MOFs; nanomedicine; cancer therapy

(This special issue belongs to the Section Materials Science)

Molecular Understanding Involved in Age-Related Diseases

edited by

David Della-Morte

and

Francesca Pacifici

submission deadline 20 Nov 2026 | 1 articles | Viewed by 912 | Submission Open

Keywords: sirtuins; frailty; aging; age-related diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Insights into Pediatric Cancer: Advances in Hematopoietic Stem Cell Research

edited by

Paola Muggeo

submission deadline 20 Nov 2026 | 1 articles | Viewed by 839 | Submission Open

Keywords: bone marrow; microenvironment; precursor; hematopoietic stem cells; pediatric hematological malignancies

(This special issue belongs to the Section Molecular Oncology)

Dietary Polyphenols and Human Health

edited by

Chunmei Li

submission deadline 20 Nov 2026 | Viewed by 790 | Submission Open

Keywords: natural polyphenols; health and disease; neurodegenerative diseases; gut microbiota; lowest effective dose; molecular mechanisms

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Human Meningioma: Recent Developments

edited by Jason P. Sheehan, Yuki Shinya and Stylianos Pikis

submission deadline 20 Nov 2026 | Viewed by 740 | Submission Open

Keywords: meningioma; molecular pathogenesis; genomic alteration; radiogenomics; tumor microenvironment; biomarkers; neurosurgery; radiosurgery; translational neuroscience; artificial intelligence

(This special issue belongs to the Section Molecular Oncology)

Molecules and Mechanisms of Oxidative Stress Relevant in the Pathophysiology of Diseases: 2nd Edition

edited by

Cinzia Signorini

submission deadline 20 Nov 2026 | 1 articles | Viewed by 589 | Submission Open

Keywords: redox-active iron; reactive oxygen species; antioxidants; oxidative damage; biomarkers; degenerative disease

(This special issue belongs to the Section Molecular Biology)

The Involvement of the Ubiquitin Proteasome System in the Healthy and Diseased Heart

edited by

Ofer Binah

submission deadline 20 Nov 2026 | Viewed by 524 | Submission Open

Keywords: UPS; ubiquitin; proteasome; cardiac pathophysiology; coronary ischemia/reperfusion injury; heart failure; cardiomyopathies; E334K mutation; cMyBPC; electrophysiological dysfunction; hypertrophic cardiomyopathy; pharmacological targeting

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

ErbB Family of Receptor Tyrosine Kinases in Cancer and Drug Therapy

edited by Ilaria Marrocco and

Donatella Romaniello

submission deadline 20 Nov 2026 | Viewed by 503 | Submission Open

Keywords: ErbB; RTKs; EGFR; HER2; HER3; cancer; targeted therapies; drug resistance

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Research in Hepatic Amino Acid Catabolism

edited by Carolina Conter

submission deadline 20 Nov 2026 | Viewed by 449 | Submission Open

Keywords: amino acid catabolism; essential amino acids; non-essential amino acids; liver metabolism; urea cycle; gluconeogenesis; lipid metabolism; nutritional regulation; mTOR signaling; metabolic diseases

(This special issue belongs to the Section Biochemistry)

Bioactive Compounds in Foods: From Structural Profiling to Bioavailability and Health Benefits

edited by Cong Wang

submission deadline 20 Nov 2026 | Viewed by 445 | Submission Open

Keywords: food bioactives; profiling; bioactive compounds; characterization; bioavailability; bioaccessibility; functionality; health-promoting benefits; structure/constituents–bioactivity relationship

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Regulation of Gene Expression in Cell Differentiation

edited by

Iole Robuffo

submission deadline 20 Nov 2026 | Viewed by 435 | Submission Open

Keywords: cell differentiation; gene expression regulation; signal transduction; autophagy; nutrigenomics; mechanobiology; longevity; aging mechanism; tumor progression; regenerative medicine; gene therapy; tissue remodeling

(This special issue belongs to the Section Molecular Genetics and Genomics)

Tau Pathology Mechanisms and Therapeutic Interventions

edited by

Claudia Marino

submission deadline 20 Nov 2026 | Viewed by 393 | Submission Open

Keywords: tau; misfolding; neurodegeneration; Alzheimer’s disease; oligomer; tauopathies; therapies; hyperphorphorylation; frontotemporal lobe dementia; synapses; spreading

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Plant Stress Resilience: Unveiling Mechanisms and Mitigation Strategies

edited by

Giuseppe Mannino

submission deadline 20 Nov 2026 | Viewed by 372 | Submission Open

Keywords: plant stress resilience; abiotic stress; biotic stress; stress signaling pathways; biostimulants; genetic and molecular mechanisms; crop improvement; GMO

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Insights into Cardiomyopathy

edited by

Selina Hein

submission deadline 20 Nov 2026 | Viewed by 365 | Submission Open

Keywords: cardiomyopathy; inflammation; molecular mechanisms; targeted therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Drug Delivery for Human Diseases: From Basic Research to Clinical Applications

edited by

Kushagra Khanna

submission deadline 20 Nov 2026 | Viewed by 190 | Submission Open

Keywords: drug delivery systems; nanomedicine; targeted therapy; traditional medicine; translational pharmaceutical research

(This special issue belongs to the Section Molecular Pharmacology)

The Impact of the Exposome on Gut Health: Deciphering Molecular Mechanisms and Pathophysiological Pathways

edited by

Sylwia Smolińska

submission deadline 20 Nov 2026 | Viewed by 185 | Submission Open

Keywords: exposome (internal & external); molecular gastroenterology; intestinal barrier function; gut-microbiota-host crosstalk; environmental toxicology; signal transduction pathways; nutritional epigenomics; metabolic dysregulation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms and Therapies of Colorectal Cancer: 5th Edition

edited by

Donatella Delle Cave

submission deadline 20 Nov 2026 | Viewed by 157 | Submission Open

Keywords: pancreatic cancer; metabolism; cellular plasticity; tumor microenvironment; target therapy

(This special issue belongs to the Section Molecular Oncology)

Latest Molecular Discoveries of Arthropod-Borne Viruses

edited by Henry Puerta-Guardo

submission deadline 20 Nov 2026 | Viewed by 155 | Submission Open

Keywords: arbovirus; whole genome sequencing; pathogenesis; transcriptomics; CRISPR-Cas9; in silico; antivirals; vaccines; diagnostics

(This special issue belongs to the Section Molecular Microbiology)

Advances in Olfactory Neurobiology, Adult Neurogenesis and Dopaminergic Neuron Research

edited by

Angela Pignatelli

submission deadline 20 Nov 2026 | Viewed by 128 | Submission Open

Keywords: olfaction; olfactory bulb; dopaminergic neurons; Parkinson’s disease; Alzheimer’s disease; adult neurogenesis; early biomarker; neurodegenerative disease; smell impairment; smell test

(This special issue belongs to the Section Molecular Neurobiology)

Role of MicroRNAs in Human Diseases: 2nd Edition

edited by

Lorenzo F. Sempere

submission deadline 25 Nov 2026 | 10 articles | Viewed by 19882 | Submission Open

Keywords: microRNAs, miRNAs, miRs; preclinical models; target interaction; regulatory networks; oncology; cancer biology; cardiovascular disease; neurodegenerative conditions; diagnostic applications; therapeutic development and clinical trials

(This special issue belongs to the Section Molecular Genetics and Genomics)

Nutrition and Cardiovascular Development, from Fetal Origins to Adulthood

edited by

Deanne H. Hryciw

submission deadline 25 Nov 2026 | Viewed by 319 | Submission Open

Keywords: fetal programming; developmental origins of health and disease; maternal nutrition; placental function; offspring; cardiovascular function; cardiometabolic risk; cardio renal development; essential fatty acids; linoleic acid

(This special issue belongs to the Section Molecular Biology)

Novel Antiviral Agents: Challenges and Opportunities from Molecular Targeting to Validation

edited by

Luis Adrián De Jesús-González

and

Moises Leon-Juarez

submission deadline 25 Nov 2026 | Viewed by 199 | Submission Open

Keywords: antiviral agents; molecular targeting; virus–host interactions; drug repurposing; host-directed antivirals; combination therapy; antiviral resistance; translational virology

(This special issue belongs to the Section Molecular Pharmacology)

Advanced 3D-Bioprinting for Next-Generation In Vitro Models: Molecular and Technological Perspectives

edited by

Alberto Portone

and

Laura Sercia

submission deadline 25 Nov 2026 | Viewed by 195 | Submission Open

Keywords: 3D bioprinting; in vitro models; biofabrication; bioinks; hydrogels; disease modeling; toxicology; drug screening; biomaterials; organ-on-a-chip

(This special issue belongs to the Section Macromolecules)

Nanomaterial: Synthesis and Application

edited by

Hesam Kamyab

submission deadline 25 Nov 2026 | Viewed by 167 | Submission Open

Keywords: nanomaterials; green synthesis; surface functionalization; nanoparticle engineering; drug delivery systems; energy storage; catalysis; environmental remediation; biocompatibility; molecular nanotechnology

(This special issue belongs to the Section Molecular Nanoscience)

Mitochondrial Functions and Dynamics

edited by

Raffaella Isola

submission deadline 27 Nov 2026 | 4 articles | Viewed by 16513 | Submission Open

Keywords: bioenergetics; mitochondrial biogenesis; mitochondrial morphology; apoptosis; mitophagy; reactive oxygen species; calcium homeostasis; cardiovascular diseases; neurodegenerative diseases; in vitro, cellular, and animal models; myopathies; mitochondria and immune system

(This special issue belongs to the Section Molecular Biology)

Molecular Insight into Catalysis of Nanomaterials

edited by Dandan Liu

submission deadline 27 Nov 2026 | 3 articles | Viewed by 5005 | Submission Open

Keywords: nanomaterial catalyst; thermal catalysis; photocatalysis; electrocatalysis; DFT calculation

(This special issue belongs to the Section Molecular Nanoscience)

Mechanisms and Effects of Endocrine Disruptors and Environmental Contaminants on Human Health

edited by

Margarida Ferreira Lorigo

submission deadline 27 Nov 2026 | 2 articles | Viewed by 4672 | Submission Open

Keywords: environmental exposure; emerging compounds; human health; risk assessment; adverse outcome pathway; new approach methodologies; one health

(This special issue belongs to the Section Molecular Toxicology)

Recent Approaches for Wound Treatment: 3rd Edition

edited by

Cinzia Pagano

Luana Perioli

and

César Viseras

submission deadline 27 Nov 2026 | 1 articles | Viewed by 3320 | Submission Open

Keywords: wound healing; inflammation; angiogenesis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Novel Insights into Buckwheat Reproductive Biology

edited by

Agnieszka Płażek

submission deadline 27 Nov 2026 | 1 articles | Viewed by 1995 | Submission Open

Keywords: antioxidant properties; biotechnological methods; embryology; seed chemical composition; yield

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Mechanisms of Various Diseases and Drugs Involved in Vascular Tone Regulation in Cardiovascular Disease

edited by

Ju-Tae Sohn

submission deadline 27 Nov 2026 | 1 articles | Viewed by 1891 | Submission Open

Keywords: vasoconstriction; vasodilation; calcium; protein kinase C; Rho-kinase; hypertension; nitric oxide

(This special issue belongs to the Section Molecular Biology)

Solid Tumours in Focus: Tissue Biomarkers and Spatial Technologies in Cancer Pathology

edited by Kathryn Pennel

submission deadline 27 Nov 2026 | 2 articles | Viewed by 1438 | Submission Open

Keywords: biomarkers; cancer pathology; spatial biology; molecular mechanisms; tumour microenvironment; cell signalling and communication

(This special issue belongs to the Section Molecular Oncology)

Tissue Engineering and Advanced Biomaterials for Regenerative Medicine

edited by

Hak Soo Choi

Motoichi Kurisawa

and

Joo Eun Chung

submission deadline 27 Nov 2026 | 1 articles | Viewed by 1310 | Submission Open

Keywords: tissue engineering; regenerative medicine; drug delivery; bioengineering; angiogenesis

(This special issue belongs to the Section Molecular Biology)

Harnessing Natural Compounds to Combat Cancer and Metastasis

edited by

Mohd Farhan

submission deadline 27 Nov 2026 | Viewed by 941 | Submission Open

Keywords: natural compounds; bioactive molecules; natural extracts; chemotherapy; immunomodulatory compounds; anti-metastatic compounds; anti-angiogenic compounds

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Cellular Plasticity in Cancer: Mechanisms, Measurement and Therapeutic Opportunities

edited by Costa Frangou and

Jianmin Zhang

submission deadline 27 Nov 2026 | 1 articles | Viewed by 898 | Submission Open

Keywords: cellular plasticity; cancer progression; EMT/MET; lineage infidelity; therapy-induced reprogramming; stem-like states; single-cell analysis; spatial transcriptomics; lineage tracing; computational modeling; biomarkers; therapeutic re-sistance; metastasis; solid tumors

(This special issue belongs to the Section Molecular Oncology)

Targeting Receptor Tyrosine Kinases and Related Signalling Pathways in Cancer: Mechanisms, Resistance, and Therapeutic Advances

edited by

Athina-Myrto Chioni

and

Richard Grose

submission deadline 27 Nov 2026 | 1 articles | Viewed by 891 | Submission Open

Keywords: tyrosine kinase receptors (TKRs); tyrosine kinase inhibitors (TKIs); cancer; therapeutic resistance/cancer drug resistance/chemotherapy resistance; signaling pathways; metastasis; combination therapy; targeted therapy; next-generation inhibitors; allosteric inhibitors; personalized medicine; tumor microenvironment; immune evasion; immunotherapy; crosstalk in cancer signaling; miRNAs; lncRNAs; cancer therapeutics; biomarkers

(This special issue belongs to the Section Molecular Oncology)

New Advances in DNA Nanotechnology

edited by Zhaoqi Yang

submission deadline 27 Nov 2026 | Viewed by 638 | Submission Open

Keywords: DNA nanotechnology; DNA-based drug delivery; DNA cages and DNA polyhedra; DNA origami; DNA-based electronic circuits; DNA-based sensors; DNA-based catalysis; DNA-based data storage

(This special issue belongs to the Section Molecular Nanoscience)

Molecular Targeting and Pharmacology of Neuroinflammation

edited by

Lisa Lione

submission deadline 27 Nov 2026 | Viewed by 592 | Submission Open

Keywords: glia-targeted therapeutics; neuroinflammation; CNS drug development; astrocyte; microglia; neurodegeneration; translational neuroscience; biomarkers; human genetics; cytokine signaling

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Research on Endocrine and Metabolic Diseases

edited by

Ferenc Sztanek

submission deadline 27 Nov 2026 | Viewed by 332 | Submission Open

Keywords: systems biology; metabolomics; fluxomics; organoid models; epigenetic regulation; precision medicine; endocrine–metabolic crosstalk

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Nanocomplexes and Drug Delivery Systems for Cancer Therapy

edited by

Ângela Sousa

submission deadline 27 Nov 2026 | Viewed by 329 | Submission Open

Keywords: nanocomplexes; drug delivery systems; cancer therapy; nanocarriers; stimuli-responsive systems; theranostics; biomolecules delivery; tumor microenvironment; personalized medicine; multidrug resistance

(This special issue belongs to the Section Molecular Nanoscience)

Current Research for Heart Disease Biology and Therapeutics: Fourth Edition

edited by Claudia Kusmic

submission deadline 29 Nov 2026 | 3 articles | Viewed by 1935 | Submission Open

Keywords: myocardial hypertrophy; cardiac remodeling; heart failure; drug therapy; molecular therapeutic targets; myocardial gene therapy; heart disease

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Displaying special issue 1401-1450 on page 29 of 64.

Go to page 27 28 29 30 31

Journal Menu

Journal Browser

Special Issues

Further Information

Guidelines

MDPI Initiatives

Follow MDPI