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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Smart and Sustainable Delivery Systems for Natural Compounds in Health and Nutrition

edited by Raffaele Conte

submission deadline 30 Jun 2026 | Viewed by 48 | Submission Open

Keywords: natural bioactive compounds; smart delivery systems; sustainable nutrition; biopolymer-based carriers; microfluidics and green technologies; controlled and targeted release; functional foods and nutraceuticals; one health approach

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Mechanisms and Therapeutic Strategies in Diabetic Retinopathy

edited by

Rosa Fernandes

submission deadline 30 Jun 2026 | Viewed by 48 | Submission Open

Keywords: diabetic retinopathy; neurovascular unit; molecular pathways; neuroinflammation; metabolic dysregulation; blood-retinal barrier; molecular biomarkers; multi-omics; molecular therapeutics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Vitamin D Metabolism and Molecular Signaling in Human Diseases

edited by

Anna Cieslinska

submission deadline 30 Jun 2026 | Viewed by 47 | Submission Open

Keywords: vitamin D; vitamin D metabolism; molecular signaling; genomic and non-genomic pathways; epigenetics; immune regulation; inflammation; metabolic disorders; autoimmune diseases; cancer biology; gut microbiota; genetic polymorphisms; precision medicine

(This special issue belongs to the Section Molecular Biology)

The Role of Gut Microbiome Regulation in Immunity and Inflammation

edited by Lei Deng

submission deadline 30 Jun 2026 | Viewed by 45 | Submission Open

Keywords: gut microbiome; adaptive immunity; IBD; inflammation; innate immunity; enteric infections; salmonella; intestine barrier; mucosal immunity

(This special issue belongs to the Section Molecular Microbiology)

Molecular and Bioactive Properties of Novel and Functional Food Ingredients

edited by

Ewelina Zielińska

submission deadline 30 Jun 2026 | Viewed by 44 | Submission Open

Keywords: functional food; bioactive compounds; novel food; molecular properties; peptides; edible insects; metabolomics; health-promoting ingredients; oxidative stress

(This special issue belongs to the Section Bioactives and Nutraceuticals)

From Molecular Design to Functional Performance: Advanced Materials for Energy and Environmental Technologies

edited by

Abu Talha Aqueel Ahmed

submission deadline 30 Jun 2026 | Viewed by 44 | Submission Open

Keywords: molecular design; molecular engineering; functional materials; organic– inorganic hybrid materials; nanostructured materials; morphology engineering; surface and interface chemistry; defect and vacancy engineering; electrocatalysis; photocatalysis; photoelectrochemical systems; energy generation and conversion; energy harvesting; energy storage; supercapacitors; lithium-ion batteries (LIBs); sodium-ion batteries (SIBs); oxygen evolution reaction (OER); hydrogen evolution reaction (HER); overall water splitting; methanol oxidation reaction (MOR); urea oxidation reaction (UOR); advanced oxidation processes (AOPs); pollutant removal and degradation; hazardous material degradation; water purification; environmental remediation; charge transfer and reaction kinetics; structure– property– performance relationships; in situ and operando spectroscopy; electrochemical characterization; density functional theory (DFT); molecular modeling and simulation; reaction mechanisms; catalyst stability and reconstruction; sustainable and green materials

(This special issue belongs to the Section Materials Science)

Advances in Plant Breeding and Biotechnology: From Lab to Field

edited by

Wenlong Bao

submission deadline 30 Jun 2026 | Viewed by 44 | Submission Open

Keywords: crop improvement; genetic transformation; omics approaches; plant metabolites; plant resistance; plant breeding

(This special issue belongs to the Section Molecular Plant Sciences)

Characterization and Biological Function of Marine Biopolymers

edited by

Zahira Belattmania

submission deadline 30 Jun 2026 | Viewed by 44 | Submission Open

Keywords: marine-based biopolymers; sustainable extractions; polymer characterization; biological functions; marine resources

(This special issue belongs to the Section Materials Science)

Molecular and Omics Insights into Stress Responses and Adaptation in Fish

edited by

Zongbin Cui

submission deadline 30 Jun 2026 | Viewed by 44 | Submission Open

Keywords: fish stress adaptation; environmental stressors; omics integration; molecular mechanisms; functional genomics; epigenetic regulation; systems biology; stress resilience

(This special issue belongs to the Section Molecular Biology)

Molecular and Translational Mechanisms of Cardiac Arrhythmias: From Oxidative Stress to Novel Therapeutic Strategies

edited by

Stefan Simović

submission deadline 30 Jun 2026 | Viewed by 44 | Submission Open

Keywords: cardiac arrhythmias; atrial fibrillation; oxidative stress; molecular mechanisms; translational research; antiarrhythmic therapy; cardiac remodeling

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms of Adipose Tissue Dysfunction

edited by

Stefano Quarta

submission deadline 30 Jun 2026 | Viewed by 43 | Submission Open

Keywords: adipose tissue dysfunction; adipogenesis; immunometabolism and adipokines; mitochondrial dysfunction; extracellular vesicles; fibrosis and ECM remodeling; lipid metabolism; browning and beigeing; metabolic biomarkers and therapeutic targets; adipose-derived stem cells

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Plant and Lichen Metabolites: Characterization and Applications

edited by

Agnieszka Hanaka

submission deadline 30 Jun 2026 | Viewed by 43 | Submission Open

Keywords: phytochemicals; secondary metabolites; bioactive compounds; bioactivity evaluation; synthesis optimization; metabolite application; metabolite extraction; elicitors; stress physiology; plant biotechnology

(This special issue belongs to the Section Molecular Plant Sciences)

Advances in Multi-Omics in Cancer: Second Edition

edited by

Leo Kei Iwai

submission deadline 30 Jun 2026 | Viewed by 43 | Submission Open

Keywords: cancer; multi-omics; genomics; transcriptomics; proteomics; metabolomics; lipidomics; epigenomics; artificial intelligence; machine learning; systems biology; biomarkers; precision oncology

(This special issue belongs to the Section Molecular Oncology)

Next-Generation Disease Models for Neuropsychiatric Disorders: Organoids, iPSC-Derived Circuits, and Gene Editing

edited by Masaru Tanaka

submission deadline 30 Jun 2026 | Viewed by 42 | Submission Open

Keywords: brain organoids; induced pluripotent stem cells (iPSC); neural stem cells; CRISPER-CAS systems (CRISPR); neuropsychiatric disorders; neurodevelopmental disorders; synaptic transmission; neuroinflammation; drug discovery; animal disease models

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Mediators at the Crossroads of Microbes, the Microbiome, and Cancer

edited by

Syed Azmal Ali

submission deadline 30 Jun 2026 | Viewed by 41 | Submission Open

Keywords: molecular mediators; microbiome-cancer interface; proteomics; multi-omics; functional characterization

(This special issue belongs to the Section Molecular Microbiology)

Genetics- and Genomics-Based Wheat Improvement and Breeding

edited by Jian Ma

submission deadline 30 Jun 2026 | Viewed by 40 | Submission Open

Keywords: wheat crop; germplasm; genetics; genomics; breeding

(This special issue belongs to the Section Molecular Plant Sciences)

Advances in the Bioactive Properties of Natural Products from Medicinal Plants: Antioxidant, Antibacterial, and Anticancer Activities

edited by Fhatuwani N. Mudau

submission deadline 30 Jun 2026 | Viewed by 40 | Submission Open

Keywords: antiproliferative properties; antimicrobial activity; medicinal plants; phytochemicals; metabolomics; natural products; cancer; therapeutic properties

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Insights into Hematopoietic Stem Cell Differentiation and Regeneration

edited by

Baobing Zhao

submission deadline 30 Jun 2026 | Viewed by 39 | Submission Open

Keywords: hematopoiesis; leukemia; lymphoma; anemia; myelodysplastic syndromes; myeloproliferative neoplasm; myelofibrosis; erythropoiesis; hematopoietic stem cell

(This special issue belongs to the Section Molecular Immunology)

Molecular Insights into Diabetic Nephropathy

edited by

Natalija Filipović

submission deadline 30 Jun 2026 | Viewed by 39 | Submission Open

Keywords: diabetic nephropathy; hyperglycemia; insulin resistance; oxidative stress; mitochondrial dysfunction; chronic kidney disease

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Latest Insight into Spin and Isomerism of Organic Molecules

edited by

Chenwei Jiang

and

Le Yu

submission deadline 30 Jun 2026 | Viewed by 39 | Submission Open

Keywords: organic molecules; photoisomerization; spin states; isomerism; spin crossover; conformational dynamics; quantum chemistry; radical chemistry; singlet fission

(This special issue belongs to the Section Molecular Biophysics)

Updates on Synthetic and Natural Antioxidants (2nd Edition)

edited by

Izabela Sadowska-Bartosz

and

Grzegorz Bartosz

submission deadline 30 Jun 2026 | Viewed by 38 | Submission Open

Keywords: antioxidants; synthetic; natural compounds

(This special issue belongs to the Section Biochemistry)

The Role of Vitamin B6 in Metabolism and Genome Stability

edited by

Fiammetta Verni

submission deadline 30 Jun 2026 | Viewed by 38 | Submission Open

Keywords: vitamin B6; PLP; DNA damage; metabolism

(This special issue belongs to the Section Molecular Biology)

Exosomes and Extracellular Vesicles in Health and Diseases: 4th Edition

edited by

Manuela Zavatti

and

Francesca Beretti

submission deadline 30 Jun 2026 | Viewed by 38 | Submission Open

Keywords: exosome; extracellular vesicles; network signals; biomarkers; pathological conditions

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Emerging Molecular Research on Photocatalytic Functional Materials

edited by Yifan Chen

submission deadline 30 Jun 2026 | Viewed by 37 | Submission Open

Keywords: photocatalytic materials; molecular level; functional optimization; mechanism; synergistic effects

(This special issue belongs to the Section Materials Science)

KCTD Proteins in Cellular Processes Regulation: Advances and Challenges

edited by

Giovanni Pecoraro

submission deadline 30 Jun 2026 | Viewed by 36 | Submission Open

Keywords: KCTD proteins; cancer biology; cell signaling pathway; ubiquitination; genetic disorder; protein– protein interaction; developmental biology; protein stability; gene expression; new therapeutic target

(This special issue belongs to the Section Molecular Biology)

Thyroid Disease: From Molecular Mechanisms to Diagnosis and Therapeutic Advances

edited by

Mariana Lorena Tellechea

and Juan Nicola

submission deadline 30 Jun 2026 | Viewed by 36 | Submission Open

Keywords: thyroid disease; hypothyroidism; hyperthyroidism; autoimmune thyroid disease; thyroid nodules; thyroid cancer

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Breast Cancer: From Pathophysiology to Novel Therapies, 2nd Edition

edited by Jennifer Sims-Mourtada

submission deadline 30 Jun 2026 | Viewed by 36 | Submission Open

Keywords: breast cancer; genetics; tumor microenvironment; model systems; organoids; immune cells; tumor stroma; therapeutic resistance; novel therapies

(This special issue belongs to the Section Molecular Oncology)

Advances in Amyloids: From Structure to Tailored Function

edited by

Laurent Marichal

submission deadline 30 Jun 2026 | Viewed by 36 | Submission Open

Keywords: amyloid; aggregation; self-assembly; seeding; protein structure

(This special issue belongs to the Section Macromolecules)

New Advances in Thrombosis: 4th Edition

edited by

Isabella Russo

submission deadline 30 Jun 2026 | Viewed by 36 | Submission Open

Keywords: thrombosis; platelets; coagulation; diabetes; obesity; insulin resistance; metabolic disease; cardiovascular diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Psychedelics and Mental Disorders: From Molecular Mechanisms to Therapies Potential

edited by

Beatriz Caballero

and

Yaiza Potes

submission deadline 30 Jun 2026 | Viewed by 36 | Submission Open

Keywords: psychedelics; drug-induced neurotoxicity; therapeutic potential; mental disorders; neuroprotective mechanisms; adult neurogenesis

(This special issue belongs to the Section Molecular Neurobiology)

Molecular and Omics Approaches in Toxicology and Precision Pharmacology

edited by

Mirjana M. Djukić

submission deadline 30 Jun 2026 | Viewed by 35 | Submission Open

Keywords: toxicology; precision pharmacology; omics technologies; proteomics; mode of action (MoA); mechanism of activity; biomarkers; prediction and modeling

(This special issue belongs to the Section Molecular Toxicology)

Phenolic Compounds as Adjunct Therapy in Cardiometabolic Disorders

edited by

Dalia Marija Kopustinskiene

submission deadline 30 Jun 2026 | Viewed by 35 | Submission Open

Keywords: phenolic compounds; cardiovascular diseases; metabolism; diabetes; obesity; hypertension; mitochondria; oxidative stress; gut microbiota; inflammation

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Cellular Immunotherapy in Cancer: Current Trends and Future Directions

edited by

Vahid Vahedian

submission deadline 30 Jun 2026 | Viewed by 35 | Submission Open

Keywords: cellular immunotherapy; CAR-T cells; CAR-NK cells; CAR-macrophages; tumor-infiltrating lymphocytes (TILs); immune receptor signaling; tumor microenvironment; CRISPR/Cas9 genome editing; precision cancer immunotherapy; translational immuno-oncology

(This special issue belongs to the Section Molecular Immunology)

New Molecular Perspectives on Diabetic Retinopathy

edited by Martina Tomić and

Tomislav Bulum

submission deadline 30 Jun 2026 | Viewed by 35 | Submission Open

Keywords: diabetic retinopathy; diabetes; complications; vascular endothelial growth factor; retina; biomarkers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Insights into Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD)

edited by Shirin Pourteymour

submission deadline 30 Jun 2026 | Viewed by 35 | Submission Open

Keywords: metabolic dysfunction-associated steatotic liver disease (MASLD); hepatic lipid metabolism; immunometabolism; inflammation and innate immunity; mitochondrial dysfunction in MASLD; genetic and epigenetic regulation; inter-organ communication; fibrosis and disease progression; translational liver biology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Cardiovascular and Vascular Biology

edited by

Woongbi Jang

submission deadline 30 Jun 2026 | Viewed by 35 | Submission Open

Keywords: cardiovascular diseases; vascular biology; molecular mechanisms; biomarkers; endothelial dysfunction; translational medicine

(This special issue belongs to the Section Molecular Biology)

Biomedical Applications of Mesenchymal Stem Cells, 2nd Edition

edited by

Giuliana Mannino

and

Debora Lo Furno

submission deadline 30 Jun 2026 | Viewed by 35 | Submission Open

Keywords: mesenchymal stem cells; cell differentiation; cell therapy; regenerative medicine; tissue homeostasis; disease; cartilage

(This special issue belongs to the Section Molecular Biology)

Cancer Drugs That Target Epigenetic Processes

edited by Eileen Brantley

submission deadline 30 Jun 2026 | Viewed by 34 | Submission Open

Keywords: histone modifications; non-coding RNA; DNA methylation; cancer agents

(This special issue belongs to the Section Molecular Oncology)

Effects of Bioactive Compounds in Cardiovascular and Neurological Diseases

edited by

Paul-Mihai Boarescu

submission deadline 30 Jun 2026 | Viewed by 34 | Submission Open

Keywords: inflammation; oxidative stress; bioactive compounds; cardiovascular diseases; neurological diseases

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Biochemistry and Biophysics Tools for Peptide and Protein Research

edited by

Wenqi Li

submission deadline 30 Jun 2026 | Viewed by 33 | Submission Open

Keywords: protein– protein interactions; peptide therapeutics development; biosensor and labeling technologies; high-throughput screening; mass spectrometry proteomics; protein dynamics and folding; single-molecule biophysics; analytical ultra-centrifugation; computational protein design; structural biology techniques

(This special issue belongs to the Section Biochemistry)

Thyroid Hormone Signaling: Mechanisms and Pathophysiological Implications

edited by

María Laura Barreiro Arcos

and Horacio Eduardo Romeo

submission deadline 30 Jun 2026 | Viewed by 33 | Submission Open

Keywords: thyroid hormones; mitochondrial function; oxidative stress; redox signaling; metabolic disorders; immune modulation; cardiovascular pathology; neurodevelopment and aging; cancer progression

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Liposome-Related Nanotechnology and Lipid-Based Nanocarriers

edited by

Carla Matos

submission deadline 30 Jun 2026 | Viewed by 33 | Submission Open

Keywords: liposomes; lipid nanoparticles; solid lipid nanoparticles; nanostructured lipid carriers; nanocarriers; drug delivery; controlled release

(This special issue belongs to the Section Molecular Nanoscience)

Advances in Research on Cotton Breeding and Genetics

edited by

Yanpeng Zhao

submission deadline 30 Jun 2026 | Viewed by 32 | Submission Open

Keywords: cotton genomics; molecular breeding; gene regulation; abiotic stress tolerance; fiber quality improvement; disease resistance; genetic engineering; marker-assisted selection; transcriptomics; genome editing

(This special issue belongs to the Section Molecular Plant Sciences)

Advances in Electrochemical Detection Research: A Molecular Insight

edited by

Gastón Pierini

submission deadline 30 Jun 2026 | Viewed by 32 | Submission Open

Keywords: electrochemical sensors; phenolic compounds; theoretical study; experimental study; nanostructured electrodes

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Trends and Prospects in Biomaterials

edited by Gabriela Graziani

submission deadline 30 Jun 2026 | Viewed by 32 | Submission Open

Keywords: biomaterials; orthopaedics; wound healing; additive manufacturing; infection; tissue modelling; tissue regeneration; orthopaedics; wound healing; antibacterial materials; regenerative medicine; reparative medicine

(This special issue belongs to the Section Materials Science)

Molecular Advances in Cancer and Cell Metabolism—3rd Edition

edited by

Maria Mesuraca

Maria Concetta Faniello

and

Barbara Quaresima

submission deadline 30 Jun 2026 | Viewed by 32 | Submission Open

Keywords: cell metabolism; cancer metabolism; cancer cell; oxidative stress; gene expression; signaling pathways; metabolic regulation; tumor growth; energy metabolism; metabolic phenotype; metabolic substrates

(This special issue belongs to the Section Molecular Oncology)

New Perspectives and Challenges in the Mechanisms, Diagnosis and Management of Skin Diseases

edited by

Emanuela Bastonini

, Daniela Kovacs and

Giorgia Cardinali

submission deadline 30 Jun 2026 | Viewed by 31 | Submission Open

Keywords: skin diseases; precision medicine; molecular pathogenesis; regenerative medicine; lipidomics; targeted biologics; inflammatory skin diseases; skin cancers; skin aging; gut– skin axis; skin regeneration

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Exploring Molecular Mechanisms Involved in Head and Neck Cancer

edited by Jae Won Chang

submission deadline 30 Jun 2026 | Viewed by 31 | Submission Open

Keywords: head and neck squamous cell carcinoma (HNSCC); molecular targeted therapy; tumor microenvironment (TME); therapeutic resistance; cancer stem cells (CSCs); immunotherapy; ferroptosis and cuproptosis; non-coding RNAs; microbiome and exosomes; precision oncology

(This special issue belongs to the Section Molecular Oncology)

Animal‐Derived Bioactive Peptides as Next‐Generation Therapeutics

edited by

Mariana S. Castro

and

Wagner Fontes

submission deadline 30 Jun 2026 | Viewed by 30 | Submission Open

Keywords: venom-derived peptides; animal toxins; antimicrobial peptides; immunomodulation; wound healing; antiparasitic agents; peptide‐based therapeutics; skin secretions

(This special issue belongs to the Section Molecular Toxicology)

Polymer Composites: Advances and Applications

edited by

Saeid Sahmani

submission deadline 30 Jun 2026 | Viewed by 30 | Submission Open

Keywords: polymer composites; polymer nanocomposites; biocompatible polymer composites; structure-property relationships; interfacial engineering; molecular design; computational modelling; mechanical performance; advanced applications

(This special issue belongs to the Section Materials Science)

Displaying special issue 2901-2950 on page 59 of 64.

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