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Advancing Molecular Psychiatry: Biomarkers, Mechanisms, and Precision Therapeutics

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".

Deadline for manuscript submissions: 30 June 2026 | Viewed by 158

Special Issue Editor


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Guest Editor
Neuroscience Research Group, Hungarian Research Network, University of Szeged (HUN-REN-SZTE), Tisza Lajos krt. 113, H-6725 Szeged, Hungary
Interests: depression; anxiety; dementia; pain; comorbidity; translational research
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We invite submissions for a Special Issue devoted to advancing translational research in molecular psychiatry and its relevance to clinical practice. This issue is intended to connect emerging molecular discoveries with meaningful applications in diagnosis, stratification, and treatment, highlighting research directions that can strengthen the move toward more precise and effective psychiatric care. We particularly welcome studies on the discovery and validation of molecular biomarkers, including genetic, epigenetic, proteomic, and metabolomic indicators, that may improve diagnostic accuracy, refine patient characterization, and support individualized therapeutic decision-making in psychiatric disorders. 

The Special Issue also welcomes contributions in pharmacogenomics, with an emphasis on how interindividual genetic differences shape treatment response, tolerability, and medication optimization in psychiatry. Such work can help reduce adverse effects and promote more rational, patient-centered prescribing strategies. In addition, we encourage submissions examining gene–environment interactions in psychiatric illness, as these studies are essential for clarifying how biological susceptibility and environmental exposures converge to influence disease onset, progression, and therapeutic response. 

We further encourage papers addressing neuroinflammation and immune-related mechanisms in psychiatric disorders, as well as neuroimaging and molecular imaging approaches that link biological alterations with symptom profiles, disease trajectories, and treatment outcomes. By bringing together these complementary perspectives, this Special Issue aims to foster clinically meaningful innovation and accelerate the translation of molecular psychiatry research into improved interventions and better patient outcomes.

Dr. Masaru Tanaka
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • brain organoids
  • induced pluripotent stem cells (iPSC)
  • neural stem cells
  • CRISPER-CAS systems (CRISPR)
  • neuropsychiatric disorders
  • neurodevelopmental disorders
  • synaptic transmission
  • neuroinflammation
  • drug discovery
  • animal disease models

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Published Papers

This special issue is now open for submission.
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