Molecular and Omics Insights into Stress Responses and Adaptation in Fish
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 30 June 2026 | Viewed by 640
Special Issue Editor
Special Issue Information
Dear Colleagues,
Environmental factors such as temperature, dissolved oxygen, salinity, and nutrition profoundly influence fish physiology, growth, and survival. These stressors affect biomolecular structures, enzymatic activities, and cellular homeostasis, driving adaptive responses critical for resilience. Despite growing interest in stress biology, the molecular sensors, signaling cascades, and gene regulatory networks underlying environmental adaptation in fish remain incompletely understood. Recent advances in functional genomics, multi-omics integration, and genome editing offer unprecedented opportunities to dissect these mechanisms. This Special Issue invites original research and reviews that leverage omics approaches—including genomics, transcriptomics, epigenetics, proteomics, and systems biology—to elucidate how fish perceive, respond to, and acclimate to environmental challenges.
We welcome studies that employ integrative and cutting-edge methodologies to explore the genetic, molecular, and physiological basis of stress adaptation in fish. Contributions may address, but are not limited to, the following themes:
- Genetic and genomic bases of stress resistance and acclimation in fish models;
- The role of population genetic diversity in shaping stress responsiveness;
- Key regulators of stress-induced gene expression programs and their molecular mechanisms;
- Epigenetic regulation of stress responses (e.g., DNA methylation, histone modifications);
- Post-transcriptional regulation under stress, including RNA splicing, editing, and structural dynamics;
- Proteomic and phosphoproteomic profiling of stress-induced signaling and regulation;
- Comparative omics analyses across fish species or populations to identify conserved and lineage-specific adaptive mechanisms.
Prof. Dr. Zongbin Cui
Guest Editor
Manuscript Submission Information
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Keywords
- fish stress adaptation
- environmental stressors
- omics integration
- molecular mechanisms
- functional genomics
- epigenetic regulation
- systems biology
- stress resilience
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