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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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The Roles of Oxidative Stress in Metabolic Syndrome

edited by

Maria Magdalena Quetglas-Llabrés

and

Margalida Monserrat-Mesquida

submission deadline 20 Feb 2026 | Viewed by 167 | Submission Open

Keywords: oxidative stress; metabolic syndrome; inflammation; antioxidants; human chronic diseases; cardiometabolic diseases; nutrition; lifestyle

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Gene Mining and Germplasm Innovation for the Important Traits in Rice (Second Edition)

edited by

Shimin Zuo

and

Yongmei Bao

submission deadline 20 Feb 2026 | Viewed by 160 | Submission Open

Keywords: rice; gene mining; important traits; molecular design; gene editing; germplasm innovation

(This special issue belongs to the Section Molecular Plant Sciences)

Advancing Mycorrhizal Research for Promoting Plant Growth Under Abiotic Stress

edited by

Catarina Campos

and

Hélia Cardoso

submission deadline 20 Feb 2026 | Viewed by 155 | Submission Open

Keywords: plant-mycorrhizal symbiosis; climate changes; environmental stress; plant stress-tolerance

(This special issue belongs to the Section Molecular Plant Sciences)

Antioxidant, Anti-Inflammatory, and Antiproliferative Activities of Natural Products—3rd Edition

edited by

Bruno Eto

submission deadline 20 Feb 2026 | Viewed by 138 | Submission Open

Keywords: bioactive products; anti-infectives; antioxidants; anti-inflammatory; antiproliferative; clinical phytopharmacology; phytopharmacology; polyphytotherapy

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Progression of Multiple Sclerosis: Environmental Factors, Genetics, Therapeutics and Immunopathogenesis

edited by Alberto Gajofatto

submission deadline 20 Feb 2026 | Viewed by 137 | Submission Open

Keywords: multiple sclerosis; disability progression; neurodegeneration; pathogenesis; immunology; risk factor; environment; genetics; treatment

(This special issue belongs to the Section Molecular Neurobiology)

Advanced Research in Immune Cell Therapy

edited by

Alexander Huang

submission deadline 20 Feb 2026 | Viewed by 137 | Submission Open

Keywords: molecular biology; bioinformatics; proteomics; molecular mechanisms; genomics

(This special issue belongs to the Section Molecular Immunology)

Theranostic Application of Reactive Oxygen Species-Sensitive Nanocarriers

edited by

Young-Il Jeong

submission deadline 20 Feb 2026 | Viewed by 128 | Submission Open

Keywords: ROS generation; ROS detection; ROS-sensitive nanoparticles; Photodynamic therapy (PDT)

(This special issue belongs to the Section Molecular Nanoscience)

Advances in Molecular Biology of Ovarian Cancer

edited by

Stefania Scicchitano

and Cinzia Garofalo

submission deadline 20 Feb 2026 | Viewed by 128 | Submission Open

Keywords: ovarian cancer; signaling pathways; transcription factors; cancer metabolism; chemoresistance; tumor microenvironment; ovarian cancer stem cells; cancer therapies

(This special issue belongs to the Section Molecular Oncology)

Natural Compounds in Cancer: Targeting Immune Cells and Signalling Pathways

edited by

Tomasz Jędrzejewski

submission deadline 20 Feb 2026 | Viewed by 126 | Submission Open

Keywords: natural compounds; cancer; inflammation; signalling pathways; antineoplastic agents; macrophage; T cells; molecular mechanism of pharmacological action; immunotherapy

(This special issue belongs to the Section Molecular Oncology)

Molecular Mechanisms, Therapeutic Challenges, and Pathogenesis of Complications in Liver Cirrhosis

edited by

Hiroteru Kamimura

submission deadline 20 Feb 2026 | Viewed by 121 | Submission Open

Keywords: muscle spasm; pruritus; sleep disturbances; sarcopenia; osteoporosis; infection; hepatopulmonary syndrome; hepatorenal syndrome; cirrhotic cardiomyopathy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms and Neural Circuits in Behavioral Neuroscience

edited by Matteo Di Segni and Rossella Ventura

submission deadline 20 Feb 2026 | Viewed by 120 | Submission Open

Keywords: behavioral neuroscience; neural circuits; psychopathology; neuroscience; drug addiction; depression; mental illness

(This special issue belongs to the Section Molecular Neurobiology)

Harnessing Bioinformatics for miRNA Research: Methods, Insights and Applications

edited by Maria Rosaria Tumolo and Saverio Sabina

submission deadline 20 Feb 2026 | Viewed by 119 | Submission Open

Keywords: microRNA; bioinformatics; hub genes; miRNA target prediction; miRNA regulatory networks; miRNA-based biomarkers; artificial intelligence in miRNA research; multi-omics approaches

(This special issue belongs to the Section Molecular Informatics)

Metal-Organic Frameworks: Pioneering New Solutions for Biomedical Challenges

edited by

David Rodríguez-Lucena

and

Belén Begines

submission deadline 20 Feb 2026 | Viewed by 115 | Submission Open

Keywords: MOFs; biomedical advances; drug delivery; personalized medicine; biomedical imaging; bio-sensor; smart MOFs; nanomedicine; cancer therapy

(This special issue belongs to the Section Materials Science)

Acute Myeloid Leukemia: From Molecular Insights to Therapeutic Innovations

edited by

Lukasz Szymanski

submission deadline 20 Feb 2026 | Viewed by 102 | Submission Open

Keywords: acute myeloid leukemia; AML; epigenetic Mechanisms; genetics; epigenetic regulation

(This special issue belongs to the Section Molecular Genetics and Genomics)

Pain: From Bench to Bedside

edited by

Christopher Robinson

and Robert J. Yong

submission deadline 20 Feb 2026 | Viewed by 92 | Submission Open

Keywords: CGRP pathway; chronic pain; drug discovery; ion channels; machine learning; molecular targets; neuroimmune signaling; non-opioid analgesics; translational pain research TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian // TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back // This page is in English Translate to Simplified Chinese Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Biosensors: Emerging Technologies and Real-Time Monitoring

edited by

Velmurugan Thavasi

submission deadline 20 Feb 2026 | Viewed by 34 | Submission Open

Keywords: biosensors; real-time monitoring; wearable sensors; electrochemical detection; optical biosensors; point-of-care (POC) diagnostics; biomarker identification and analysis; wireless technologies

(This special issue belongs to the Section Biochemistry)

Toxicological Impacts of Emerging Contaminants on Aquatic Organisms

edited by

Mohamed Hamed

submission deadline 20 Feb 2026 | Viewed by 26 | Submission Open

Keywords: aquatic toxicology; emerging contaminants; physiology and behavior; oxidative stress; antioxidant biomarkers; immunotoxicity; neuroendocrine toxicity; bioremediation; molecular mechanisms

(This special issue belongs to the Section Molecular Toxicology)

Molecular Biology of the Thyroid Cancer and Thyroid Dysfunctions: 2nd Edition

edited by Vija Lavinia

submission deadline 20 Feb 2026 | Viewed by 11 | Submission Open

Keywords: animal models; apoptosis; autophagy; cancer biomarker; cancer epidemiology; cancer prevention; cancer screening; cholesterol metabolism; clinical trial; DNA repair; epigenomics; genome instability; genomic database; genomics; invasion; metabolomics; metastasis; methylation; microarray; microRNA; molecular diagnostics; molecular tumor pathology; next-generation sequencing; noncoding RNA; omics; personalized medicine; prognosis; proteomics; radionuclide therapy; signaling pathway; SNP genotyping; targeted therapy; theranostics; thyroid cancer; hyperthyroidism; therapeutic targets; translational cancer research; treatment response; tumor microenvironment

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

AIEgens in Action: Design, Mechanisms, and Emerging Applications

edited by

Arkadiusz Matwijczuk

submission deadline 20 Feb 2026 | Viewed by 4 | Submission Open

Keywords: fluorescence effects; photophysical properties of small molecules; ion detection; molecular spectroscopy; various nanoparticle-based additives; fluorescent and phosphorescent phenomena in solvents; amorphous states; and crystals; quantum-mechanical calculations for molecular systems and compositions (DFT; TD-DFT); molecular aggregation influencing fluorescence and phosphorescence properties of tested systems

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Molecular Advances in Gestational Diabetes Mellitus: 2nd Edition

edited by Natasha Singh

submission deadline 20 Feb 2026 | Viewed by 2 | Submission Open

Keywords: metabolome; placental insulin signaling; DNA methylation; mitochondrial oxidation; MTOR; amino acids lipidomics; proteomics; gluconeogenesis; GDM

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Understanding Aging in Health and Disease

edited by

Laura Cianfruglia

submission deadline 25 Feb 2026 | 1 articles | Viewed by 400 | Submission Open

Keywords: immunosenescence; age-related disease; ageing; oxidative stress; inflammaging

(This special issue belongs to the Section Molecular Biology)

Obesity: From Cellular Mechanism to Potential Molecular Therapies

edited by

Veronica Jimenez

submission deadline 25 Feb 2026 | Viewed by 48 | Submission Open

Keywords: metabolic pathways; gene expression; epigenetics; obesity-related comorbidities; molecular biomarkers; adipogenesis; therapeutic interventions; small molecules; gene therapy/gene editing; obesity and cancer

(This special issue belongs to the Section Molecular Biology)

Molecular Research in Chronic Inflammatory Sinonasal Diseases

edited by Santos Tiago Soares

submission deadline 25 Feb 2026 | Viewed by 25 | Submission Open

Keywords: chronic rhinosinusitis; nasal polyps; type 2 inflammation; sinonasal immunopathology; molecular pathways; host– microbiome interaction; precision medicine; upper airway disease; translational research

(This special issue belongs to the Section Molecular Immunology)

Molecular Pathophysiology and Treatments of Diabetes

edited by

Carlo Acierno

submission deadline 26 Feb 2026 | Viewed by 77 | Submission Open

Keywords: diabetes mellitus; molecular pathophysiology; insulin resistance; beta-cell dysfunction; chronic inflammation; epigenetics; metabolic syndrome; SGLT2 inhibitors; GLP-1 receptor agonists; gut microbiota

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Drug Discovery Based on Natural Products

edited by Woo-kyung Kim

submission deadline 28 Feb 2026 | 5 articles | Viewed by 7067 | Submission Open

Keywords: drug discovery; bioactive compounds; pharmacological activities and mechanisms; omics technologies

(This special issue belongs to the Section Molecular Pharmacology)

Current Trends and Future Directions in Antimicrobial Peptide Research

edited by

Sara Elsa Aita

submission deadline 28 Feb 2026 | Viewed by 62 | Submission Open

Keywords: antimicrobial peptides (AMPs); host defense; structure-function; antimicrobial agents; biomedical applications; antibiotic alternatives; antibiotic resistance

(This special issue belongs to the Section Molecular Biology)

Biomaterials: From Design, Synthesis and Characterization to Application—2nd Edition

edited by

Tao Sun

and

Xujin Bao

submission deadline 28 Feb 2026 | Viewed by 39 | Submission Open

Keywords: biomaterials; synthesis; characterization; therapeutics; diagnosis

(This special issue belongs to the Section Materials Science)

Role of Extracellular Vesicles in Immune Regulation

edited by Rachel Crossland

submission deadline 28 Feb 2026 | Viewed by 38 | Submission Open

Keywords: extracellular vesicle; immune regulation; immunomodulation; antigen presentation; inflammation; autoimmunity

(This special issue belongs to the Section Molecular Immunology)

Strategies for Enhancing Skeletal Muscle Recovery and Regeneration in Health and Disease Conditions

edited by

Elen Miyabara

and

Atsushi Asakura

submission deadline 28 Feb 2026 | Viewed by 35 | Submission Open

Keywords: skeletal muscle; regeneration; muscle wasting; aging; muscle diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Dermatological Perspectives on Connective Tissue Diseases

edited by Yoshihide Asano

submission deadline 28 Feb 2026 | Viewed by 21 | Submission Open

Keywords: connective tissue diseases; systemic sclerosis; systemic lupus erythematosus; dermatomyo-sitis; rheumatoid arthritis; Sjö gren’ s syndrome; skin immunology; fibrosis; cytokines; targeted therapy

(This special issue belongs to the Section Molecular Biology)

Alcohol Use Disorder: From Molecular Mechanisms to Therapeutics

edited by

Giampiero Ferraguti

submission deadline 28 Feb 2026 | Viewed by 1 | Submission Open

Keywords: alcohol; addiction; FASD; alcohol-related damage

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms and Therapies of Chronic Obstructive Pulmonary Disease

edited by

Marija Stankovic

submission deadline 20 Mar 2026 | 7 articles | Viewed by 18112 | Submission Open

Keywords: COPD; molecular mechanism; inflammation; therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Lung Cancers: An Update on Molecular Diagnostics and Therapy

edited by

Mariusz Chabowski

submission deadline 20 Mar 2026 | 6 articles | Viewed by 16463 | Submission Open

Keywords: lung cancer; cancer cachexia; prognosis; anti-lung cancer agents

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular and Cellular Perspectives on Wound Healing

edited by

Ermelindo C. Leal

and

Eugenia Carvalho

submission deadline 20 Mar 2026 | 5 articles | Viewed by 11886 | Submission Open

Keywords: chronic wound healing; scarring; biomarkers; inflammation; angiogenesis; infection; extracellular matrix; biomaterials; tissue regeneration; therapeutic targets; innovative therapies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Advances in Medical Microbiology

edited by

Alberto Rizzo

submission deadline 20 Mar 2026 | 4 articles | Viewed by 8189 | Submission Open

Keywords: clinical microbiology; clinical virology; SARS-CoV-2; HPV; sexually transmitted infections; respiratory viruses; emerging pathogens; opportunistic infections

(This special issue belongs to the Section Molecular Microbiology)

Beyond Digestion: The Role of Gut Microbiota in Metabolism, Immunity and Brain Function

edited by

Alip Borthakur

submission deadline 20 Mar 2026 | 5 articles | Viewed by 7180 | Submission Open

Keywords: gut dysbiosis; gut microbiota; metabolism

(This special issue belongs to the Section Molecular Immunology)

Unraveling the Molecular Mechanisms of Neurodegeneration

edited by

Michela Ferrucci

submission deadline 20 Mar 2026 | 4 articles | Viewed by 6309 | Submission Open

Keywords: protein accumulation; mitochondria; genetic and epigenetic alterations; oxidative stress; apoptosis; autophagy

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Insights into Zoonotic Diseases

edited by

Vishwanath Venketaraman

submission deadline 20 Mar 2026 | 3 articles | Viewed by 5457 | Submission Open

Keywords: mycobacterial diseases; bubonic and pneumonic plague; Q fever; cat scratch disease; Mediterranean fever; HIV; malaria; ADIS; SARS-CoV-2; adjunctive therapy; immune-enhancing agents; antimycobacterial compounds; host-directed therapies; pathogenesis; modulation of host immune responses

(This special issue belongs to the Section Molecular Microbiology)

Signaling Pathways and Novel Therapies in Heart Disease

edited by

Anindita Das

submission deadline 20 Mar 2026 | 2 articles | Viewed by 5258 | Submission Open

Keywords: heart failure; arrhythmias; ischemic heart disease; myocardial regeneration; inflammation; gene- or cell-based therapy; precision medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Protein Aggregation and Proteinopathies

edited by Hongyu Hu

submission deadline 20 Mar 2026 | 2 articles | Viewed by 5196 | Submission Open

Keywords: protein aggregation; inclusion; sequestration; interaction; phase transition; proteostasis; proteinopathy

(This special issue belongs to the Section Molecular Biology)

Inflammatory Bowel Disease and Microbiome

edited by Abigail Raffner Basson

submission deadline 20 Mar 2026 | 4 articles | Viewed by 4997 | Submission Open

Keywords: inflammatory bowel disease; Crohn’ s disease; ulcerative colitis; gut microbiota; diet; treatment; pathogenesis; biomarker

(This special issue belongs to the Section Molecular Microbiology)

New Strategies to Improve the Detection of Human Papillomavirus (HPV) Persisting Infections

edited by

Marianna Martinelli

submission deadline 20 Mar 2026 | 4 articles | Viewed by 4691 | Submission Open

Keywords: human papillomavirus; HPV; viral load; genotyping; oncogenic transcripts; biomarkers

(This special issue belongs to the Section Molecular Microbiology)

Lipid Metabolism in Human Health and Diseases

edited by

Arianna Vignini

submission deadline 20 Mar 2026 | 2 articles | Viewed by 4058 | Submission Open

Keywords: lipids; fatty acids; lipid metabolism; metabolic disorders; cardiovascular diseases; neurodegenerative diseases; cancers

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Understanding Allergy and Asthma at the Molecular Level

edited by

Cenk Suphioglu

submission deadline 20 Mar 2026 | 1 articles | Viewed by 4055 | Submission Open

Keywords: allergy; asthma; allergens; allergic asthma; thunderstorm asthma; cell culture; biomarkers; proteomics; metabolomics; lipidomics; genomics; recombinant allergens; recombinant hypoallergens; signalling; inhibitors; cytokines

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Protein Methyltransferases in Human Health and Diseases

edited by

Byron Baron

submission deadline 20 Mar 2026 | 1 articles | Viewed by 3949 | Submission Open

Keywords: lysine and arginine methylation; mass spectrometry; PTM cross talk; functional proteomics; cancer; neurological disorders

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Therapies and Strategies in the Treatment of Neurodegenerative Diseases

edited by

Polina Petkova-Kirova

submission deadline 20 Mar 2026 | 2 articles | Viewed by 3859 | Submission Open

Keywords: neurodegenerative diseases; Alzheimer’ s disease; Parkinson’ s disease; Huntington’ s disease; aging; memory; dementia; motor dysfunction

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Therapeutics for Diabetes and Related Complications, 2nd Edition

edited by

Kota V. Ramana

submission deadline 20 Mar 2026 | 4 articles | Viewed by 3571 | Submission Open

Keywords: diabetes; diabetes complications; molecular therapeutics; drug development; hyperglycemia; insulin resistance; cell signaling and oxidative stress

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Exploring Biological Mechanisms and Therapeutic Strategies for Substance Use Disorders

edited by Thomas Paparrigopoulos

submission deadline 20 Mar 2026 | 2 articles | Viewed by 3207 | Submission Open

Keywords: addiction; alcohol use disorder; opioid use disorder; substance use disorders; physical exercise; physical activity; molecular mechanisms; neuroendocrine system

(This special issue belongs to the Section Molecular Neurobiology)

New Trends and Challenges in Chronic Diseases

edited by

Guan-Jhong Huang

submission deadline 20 Mar 2026 | 2 articles | Viewed by 2417 | Submission Open

Keywords: chronic diseases; ER stress; oxidative stress; immune regulation; new pathways of pathogenesis; cancer development

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Mitochondria: Central Players in Cancer

edited by

Annamaria Piscazzi

and

Domenica Mangieri

submission deadline 20 Mar 2026 | 2 articles | Viewed by 2184 | Submission Open

Keywords: mitochondria; cancer; tumorigenesis; oxidative phosphorylation; glycolysis; Warburg effect; reactive oxygen species (ROS); apoptosis; mitochondrial dysfunction; metabolic reprogram-ming; cancer therapy

(This special issue belongs to the Section Molecular Biology)

Displaying special issue 3251-3300 on page 66 of 68.

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