Dermatological Perspectives on Connective Tissue Diseases

Dear Colleagues,

Connective tissue diseases (CTDs), including systemic sclerosis, systemic lupus erythematosus, dermatomyositis, rheumatoid arthritis, and Sjögren’s syndrome, frequently involve the skin and mucosa, with manifestations that provide critical diagnostic and prognostic information. These dermatological findings often mirror the underlying autoimmune, inflammatory, and fibrotic processes that characterize CTDs. Recent advances in molecular and cellular biology have elucidated key mechanisms such as dysregulated cytokine networks, aberrant immune cell activation, endothelial dysfunction, and tissue remodeling. Understanding these processes from a dermatological perspective not only aids in early diagnosis and monitoring but also contributes to the development of targeted therapies. This Special Issue will bring together cutting-edge research and reviews that explore the skin-related aspects of CTDs from molecular mechanisms and biomarkers to translational research and clinical applications. Contributions that highlight interdisciplinary approaches and novel therapeutic strategies are especially welcome.

Dr. Yoshihide Asano
Guest Editor

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