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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advanced Research in Crops: From Physiology to Breeding

edited by

Guang Chen

and Edyta Zdunek-Zastocka

submission deadline 20 Oct 2026 | 1 articles | Viewed by 760 | Submission Open

Keywords: crops; stress; cultivation measures; molecular mechanisms; breeding

(This special issue belongs to the Section Molecular Plant Sciences)

The Plant Phenotyping and Phenomics for Breeding

edited by

Jaeil Lyu

submission deadline 20 Oct 2026 | Viewed by 706 | Submission Open

Keywords: plant phenomics; high-throughput phenotyping (HTP); genotype–phenotype association; non-invasive imag-ing; functional genomics; environmental interactions

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Mechanisms and Therapeutic Strategies for Oral Mucosal Diseases: From Radiotherapy-Induced Damage to Other Pathologies

edited by

Fernanda Gonçalves Salum

submission deadline 20 Oct 2026 | 1 articles | Viewed by 695 | Submission Open

Keywords: oral mucosal diseases; drug-induced oral lesions; radiotherapy- and chemotherapy-induced oral disorders; targeted therapy- and immunotherapy-induced stomatitis; oxidative stress and inflammation; oral microbiome and immunity; nanomedicine and biomaterials; photobiomodulation and photodynamic therapy; oral potentially malignant disorders; oral oncology; immune modulation; tissue regeneration and repair; translational research; investigational therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms and Pathophysiology of Nerve Regeneration

edited by Fabian Szepanowski and Mark Stettner

submission deadline 20 Oct 2026 | 1 articles | Viewed by 684 | Submission Open

Keywords: nerve injury; nerve inflammation; autoimmune neuropathies; immune-mediated neuropathies; polyneuropathies; peripheral neuroinflammation; nerve regeneration; Schwann cell; Schwann cell differentiation; repair Schwann cell

(This special issue belongs to the Section Molecular Neurobiology)

Mitochondrial Disorders: From Molecular Mechanisms to New Therapies

edited by

Yury Ladilov

and

Muhammad Aslam

submission deadline 20 Oct 2026 | Viewed by 657 | Submission Open

Keywords: mitochondrial disorders; mitochondrial dysfunction; molecular mechanisms; targeted therapeutic approaches; mitochondrial biology regulation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Electrochemical Detection: A Molecular-Level Perspective

edited by Katarzyna Fendrych and

Joanna Smajdor-Baran

submission deadline 20 Oct 2026 | 1 articles | Viewed by 619 | Submission Open

Keywords: electrochemical detection; molecular sensing; biosensors; nanostructured electrodes; biomolecular interactions; electroanalytical chemistry; molecular electrochemistry

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Advances in Drug Discovery: Emerging Radiotracers and Small Molecule Inhibitors for Cancer and Neurological Disorders

edited by

Ramya Tokala

submission deadline 20 Oct 2026 | 1 articles | Viewed by 580 | Submission Open

Keywords: radiotracers; cytotoxic agents; drug discovery; molecular imaging; cancer therapy; neurological disorders; radiochemistry; medicinal chemistry; theranostics; drug development; molecular diagnostics

(This special issue belongs to the Section Molecular Pharmacology)

Advances in the Nanoparticles-Based Drug Delivery in Cancer Therapy

edited by

André F. Moreira

submission deadline 20 Oct 2026 | Viewed by 562 | Submission Open

Keywords: nanoparticle-based drug delivery; stimuli responsive; cancer targeting; theragnostic nanoparticles; protein corona; combinatorial drug therapies; tumor penetration; cancer cells uptake

(This special issue belongs to the Section Molecular Nanoscience)

The Impact of Circulating Biomarkers and Metabolites on Cardiometabolic Disease and Cancer: New Insights and Therapeutic Opportunities

edited by Melania Gaggini and

Cristina Vassalle

submission deadline 20 Oct 2026 | Viewed by 462 | Submission Open

Keywords: lipidomic; metabolomic; lipotoxicity; oxidative stress; amino acids; metabolic disease; cardiovascular risk; tumorigenesis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Exploring Molecular Progression in Inorganic Synthesis

edited by

Suraj Kumar Pathak

submission deadline 20 Oct 2026 | Viewed by 460 | Submission Open

Keywords: inorganic synthesis; materials science; catalysis; energy materials; bioinorganic systems; organometallic compounds; supramolecular chemistry; molecular design

(This special issue belongs to the Section Materials Science)

Activation of the Blood–Brain Barrier and Neurological Dysfunction: 2nd Edition

edited by

Monique F. Stins

submission deadline 20 Oct 2026 | Viewed by 374 | Submission Open

Keywords: blood–brain barrier; neuro-infectious diseases; microbes; traumatic brain injury; Alzheimer’s disease; Parkinson’s disease; schizophrenia; cerebral vasculature; vascular heterogeneity; white matter; gray matter; therapeutic delivery; opening the BBB; neuro vascular unit

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Insights into Allergic Asthma

edited by

Luisa Ricciardi

submission deadline 20 Oct 2026 | Viewed by 368 | Submission Open

Keywords: allergic asthma; molecular mechanisms; allergen exposure; T2 inflammation; inhaler treatment; biological treatment

(This special issue belongs to the Section Molecular Immunology)

Molecular Mechanisms of SARS-CoV-2 Infection and Pathogenesis

edited by

Virginia Lotti

and

Erica Diani

submission deadline 20 Oct 2026 | Viewed by 367 | Submission Open

Keywords: SARS-CoV-2; molecular virology; host–pathogen interactions

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Cancer Nanomedicine: Imaging, Targeting and Therapeutic Applications

edited by

Marvin Xavierselvan

and

Steven Fiering

submission deadline 20 Oct 2026 | Viewed by 364 | Submission Open

Keywords: cancer nanomedicine; multimodal imaging; nanoparticle drug delivery; tumor targeting; theranostic nanoparticles; combination therapies

(This special issue belongs to the Section Molecular Nanoscience)

Epigenetic Elicitation of Dormant Microorganisms for Anti-Cancer Therapy

edited by

Komal Anjum

submission deadline 20 Oct 2026 | Viewed by 297 | Submission Open

Keywords: dormant microbes; epigenetic; bioactive molecules; anti-cancer therapy; biosynthetic pathways; bioactive secondary metabolites

(This special issue belongs to the Section Molecular Genetics and Genomics)

Advances in Diagnostic, Prognostic and Predictive Biomarkers in Prostate Cancer

edited by Radka S. Stoyanova

submission deadline 20 Oct 2026 | Viewed by 294 | Submission Open

Keywords: prostate cancer; molecular biomarkers; imaging; non-invasive biomarkers; liquid biopsy

(This special issue belongs to the Section Molecular Oncology)

Advances in Immunotherapy for Cancer: From Molecular Basis to Novel Biomarkers and Therapeutic Targets—2nd Edition

edited by

Laura Conti

and

Valentina Audrito

submission deadline 20 Oct 2026 | Viewed by 293 | Submission Open

Keywords: tumor microenvironment; immune suppression; metabolic and molecular mechanisms of resistance to therapy; tumor immune escape; immunotherapy; immune checkpoint inhibitors; cancer vaccination; tumor-infiltrating cells; biomarkers; tumor antigens; cancer metabolism

(This special issue belongs to the Section Molecular Oncology)

Advanced Molecular Research in Bio-Based Polymeric Materials

edited by

Wanwitoo Wanmolee

submission deadline 20 Oct 2026 | Viewed by 276 | Submission Open

Keywords: bio-based polymers; lignin; cellulose; biopolymers; sustainable materials; green chemistry; biomass valorization; biocomposites; functional materials; sustainable packaging

(This special issue belongs to the Section Materials Science)

Sustainable Nanomaterials for Environmental Remediation

edited by

Odín Reyes−Vallejo

and

Francisco J. Cano

submission deadline 20 Oct 2026 | Viewed by 255 | Submission Open

Keywords: nanomaterials; environmental remediation; adsorption; photocatalysis; membrane separation; biomass-derived materials; sustainable and conventional synthesis; CO2 capture and conversion; water, air, and soil treatment; structure–property relationships

(This special issue belongs to the Section Molecular Nanoscience)

Omics-Based Regulatory Networks in Plant Abiotic Stress Tolerance

edited by

Xujun Zhu

submission deadline 20 Oct 2026 | Viewed by 199 | Submission Open

Keywords: omics; plant abiotic stress tolerance; drought/salt/heat stress; genomics; transcriptomics; proteomics; metabolomics; epigenomics; stress regulatory networks; crop resilience

(This special issue belongs to the Section Molecular Plant Sciences)

The Involvement of Stem Cells in Cancer

edited by

Kuo-Shyang Jeng

submission deadline 20 Oct 2026 | Viewed by 196 | Submission Open

Keywords: cancer; stem cells; signaling pathways; self-renewal; treatment

(This special issue belongs to the Section Molecular Oncology)

Molecular Research in Obesity and Obesity Related Disorders: 4th Edition

edited by

Grażyna Nowicka

submission deadline 20 Oct 2026 | Viewed by 174 | Submission Open

Keywords: adipocyte biology; adipocyte tissue; adipocyte tissue dysfunction; cellular patterns; molecular patterns; epigenetics; gene expression; DNA damage; inflammation; oxidative stress; metabolic disorders; cancer

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Neural Damage and Fibrosis: From Mechanisms to Therapy

edited by

Savaș Kaya

and Ayça Taş

submission deadline 20 Oct 2026 | Viewed by 174 | Submission Open

Keywords: fibrosis; inflammation; oxidative stress; glial activation; neurodegeneration; gene expression; molecular signaling pathways; biomarkers; translational research

(This special issue belongs to the Section Molecular Neurobiology)

New Molecular Insights for Enhancing Plant Resilience to Abiotic Stress

edited by

Aliki Kapazoglou

submission deadline 20 Oct 2026 | Viewed by 162 | Submission Open

Keywords: abiotic stress; tolerance; plant resilience; crop sustainability; environmental conditions; climate change; gene regulation; epigenetic mechanisms; microbiome

(This special issue belongs to the Section Molecular Plant Sciences)

The Role of Fatty Acids in Metabolic Disease

edited by

Danijela Ristić-Medić

and

Snježana Petrović

submission deadline 20 Oct 2026 | Viewed by 147 | Submission Open

Keywords: fatty acids; FADS; inflammation; insulin resistance; lipid mediators; lipid metabo-lism; lipotoxicity; metabolic diseases; nutrition; oxidative stress

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Advances in Plant Genomics and Genetics: 4th Edition

edited by

Hengling Wei

submission deadline 20 Oct 2026 | Viewed by 137 | Submission Open

Keywords: plant genomics; plant genetics; abiotic stresses; salt resistance; genome; next-generation sequencing

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Microbiology in the Omics Era: Genomics, Metagenomics and Computational Insights

edited by

Fei Liu

submission deadline 23 Oct 2026 | 2 articles | Viewed by 12916 | Submission Open

Keywords: microbial genomics; metagenomics; computational biology; antimicrobial resistance; host–microbe interactions; multi-omics integration; bioinformatics tools; machine learning in microbiology

(This special issue belongs to the Section Molecular Microbiology)

Molecular and Neuromuscular Mechanisms in Skeletal Muscle Aging, 2nd Edition

edited by

Rosa Mancinelli

submission deadline 23 Oct 2026 | 5 articles | Viewed by 12366 | Submission Open

Keywords: aging; sarcopenia; neuromuscular junction; molecular muscle modifications; myokines

(This special issue belongs to the Section Molecular Biology)

Antioxidants: The Molecular Guardians Against Oxidative Stress

edited by

Karolina A. Wojtunik-Kulesza

submission deadline 23 Oct 2026 | 5 articles | Viewed by 10688 | Submission Open

Keywords: antioxidant; free radical; oxidative stress; essential oils; secondary plant metabolites

(This special issue belongs to the Section Biochemistry)

Latest Advances in Oxidative Stress and Brain Injury

edited by

Vittorio Fineschi

submission deadline 23 Oct 2026 | 2 articles | Viewed by 10616 | Submission Open

Keywords: measurement of ROS; pathology of brain injuries; traumatic brain injuries; hypoxic–ischemic brain damage; experimental models of brain injury; targeted therapy of brain injuries; drug abuse and ROS; histological diagnosis of brain injuries; epigenetics of brain injuries; miRNA and prognosis of neural damage; novel approaches and proofs of principle in therapy; quality of life after brain injury

(This special issue belongs to the Section Molecular Neurobiology)

Eye Diseases: From Pathophysiology to Novel Therapeutic Approaches

edited by

Tomasz Chorągiewicz

and

Joanna Dolar-Szczasny

submission deadline 23 Oct 2026 | 5 articles | Viewed by 10587 | Submission Open

Keywords: eye diseases; genetic; biochemical; proteomic; cellular and physiological level; innovative therapeutic approaches

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Recent Research on Biomimetic Chromatography, QSAR and Chemoinformatics in Molecular Modeling and Drug Design

edited by

Małgorzata Janicka

submission deadline 23 Oct 2026 | 5 articles | Viewed by 8073 | Submission Open

Keywords: biomimetic chromatography; QSARs; QRARs; molecular modelling; chemoinformatics; pharmacokinetics

(This special issue belongs to the Section Molecular Informatics)

The Role of Natural Products in Inflammation

edited by

Antonia Cianciulli

submission deadline 23 Oct 2026 | 3 articles | Viewed by 8047 | Submission Open

Keywords: inflammation; natural products; immunomodulation; bioactive compounds; drug discovery; drug target identification; anti-inflammatory activity; antioxidant activity; cellular signalling pathways

(This special issue belongs to the Section Molecular Pharmacology)

Osteoimmunology: Interactions of the Bone and Immune System

edited by

Galliera Emanuela Rita

submission deadline 23 Oct 2026 | 2 articles | Viewed by 7756 | Submission Open

Keywords: osteoimmunology markers; bone infection; inflammation and bone; immune response and bone; diagnostic and prognostic markers; bone remodeling; osteoclasts; immune-mediated bone diseases; bone–immune interface

(This special issue belongs to the Section Molecular Immunology)

Radiobiology—New Advances

edited by

Marco Calvaruso

and

Luigi Minafra

submission deadline 23 Oct 2026 | 3 articles | Viewed by 5996 | Submission Open

Keywords: radiobiology; radiotherapy; radiosensitizing agents; radioresistance; DNA damage; FLASH radiotherapy; particle therapy

(This special issue belongs to the Section Molecular Biology)

Molecular Research and Applications of Nanomaterials

edited by

Sónia Carabineiro

submission deadline 23 Oct 2026 | 4 articles | Viewed by 5647 | Submission Open

Keywords: molecular research; application; functionality of nanomaterials; catalysis; environmental science

(This special issue belongs to the Section Molecular Nanoscience)

Antifungal Potential of Botanical Compounds

edited by Francisca Sempere-Ferre

submission deadline 23 Oct 2026 | 2 articles | Viewed by 5626 | Submission Open

Keywords: botanical compounds; antifungal agents; natural products; secondary metabolites; fungal growth inhibition; bioactive plant extracts; eco-friendly antifungals; natural product chemistry; sustainable antifungal solutions; plant-derived bioactives

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Inflammatory Bowel Disease: Molecular Insights—2nd Edition

edited by

Belal Chami

submission deadline 23 Oct 2026 | 4 articles | Viewed by 3831 | Submission Open

Keywords: genomic sequencing; microbiome; dysbiosis; commensal flora; omics; immunobiology; colitis; Crohn’s disease; ulcerative colitis; multiomics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Research on Alloy Materials Microstructure and Their Functionalization

edited by

Ozkan Gokcekaya

and Celaletdin Ergun

submission deadline 23 Oct 2026 | 2 articles | Viewed by 3653 | Submission Open

Keywords: alloy design; microstructure; production methods; additive manufacturing; sol–gel process; biofunctional materials; magnetic properties; nanoparticles; ceramics; composites

(This special issue belongs to the Section Materials Science)

Trace Elements, Metals and Bioactive Compounds: Homeostasis and Metabolic Impairment

edited by

Graziantonio Lauria

and

Rosita Curcio

submission deadline 23 Oct 2026 | 1 articles | Viewed by 3159 | Submission Open

Keywords: trace elements; bioactive compounds; metals; human health; human diseases

(This special issue belongs to the Section Biochemistry)

Molecular Advancements in Functional Materials

edited by

Joanna Karasiewicz

submission deadline 23 Oct 2026 | 4 articles | Viewed by 3064 | Submission Open

Keywords: synthesis of specialty compounds; specialty compounds in functional materials; special applications: self-cleaning, anti-icing, self-healing, biocidal, etc., properties; special-purpose functional materials

(This special issue belongs to the Section Materials Science)

Molecular Research Advances in Common and Rare Pediatric Diseases

edited by

Lǎcrǎmioara Ionela Butnariu

submission deadline 23 Oct 2026 | 3 articles | Viewed by 2898 | Submission Open

Keywords: pediatric diseases; diagnosis; therapeutic targets; molecular mechanisms; pediatric pathology; signaling pathways

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms of Plant Adaptation to Stress

edited by Yuanchun Ma

submission deadline 23 Oct 2026 | 4 articles | Viewed by 2823 | Submission Open

Keywords: plant; environmental stresses; signaling pathways; stress-responsive genes; transcription factors; phytohormones; crop resilience; breeding; genetic engineering

(This special issue belongs to the Section Molecular Plant Sciences)

AI and Machine Learning in Molecular Biomarker Discovery and Mechanisms of Neurodegenerative Disorders

edited by

Seyed Ehsan Saffari

submission deadline 23 Oct 2026 | 2 articles | Viewed by 2596 | Submission Open

Keywords: artificial intelligence (AI); machine learning (ML); biomarker discovery; neurodegenerative disorders; Alzheimer’s disease (AD); Parkinson’s disease (PD); dementia; risk prediction models; multi-omics integration; translational bioinformatics

(This special issue belongs to the Section Molecular Neurobiology)

Cancer Progression and Therapeutic Resistance Mechanisms

edited by

Fabrizio Fontana

submission deadline 23 Oct 2026 | 1 articles | Viewed by 2584 | Submission Open

Keywords: cancer drug resistance; growth factors; DNA repair; miRNAs; ABC transporters; cancer stem cells; extracellular vesicles; circulating cancer cells; circulating cancer DNA; liquid biopsies; natural anticancer compounds

(This special issue belongs to the Section Molecular Oncology)

Molecular Mechanisms of Hematologic Disorders

edited by

Valentina Giudice

submission deadline 23 Oct 2026 | 2 articles | Viewed by 2116 | Submission Open

Keywords: solid tumors; hematologic disorders; hematology; bone marrow failure; leukemia; myeloma

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Design and Functional Applications of Polysaccharide Composites

edited by

Magdalena Krystyjan

Gohar Khachatryan

and

Karen Khachatryan

submission deadline 23 Oct 2026 | 1 articles | Viewed by 1444 | Submission Open

Keywords: polysaccharide composites; molecular design; functional applications

(This special issue belongs to the Section Materials Science)

Advances in the Role of Retinoic Acid-Regulated Genes in Cancer Biology

edited by Fuming Tsai

submission deadline 23 Oct 2026 | 2 articles | Viewed by 1382 | Submission Open

Keywords: retinoic acid; retinoic acid receptors; retinoic x receptors; tumorigenesis; metastasis; tumor microenvironment; molecular pathways

(This special issue belongs to the Section Molecular Genetics and Genomics)

Targeted Therapy for Breast and Gynecological Cancer

edited by Moira Ragazzi and Elisa Gasparini

submission deadline 23 Oct 2026 | 2 articles | Viewed by 1297 | Submission Open

Keywords: breast cancer; gynecological cancer; target therapy; biomarkers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Metabolic–Epigenetic Interplay in Health and Diseases

edited by

Ana Paula De Souza

submission deadline 23 Oct 2026 | 1 articles | Viewed by 1039 | Submission Open

Keywords: epigenetics; metabolism; TCA cycle; one-carbon cycle; aging; longevity; cancer; metabolic syndrome; neurodegeneration

(This special issue belongs to the Section Molecular Neurobiology)

Displaying special issue 1301-1350 on page 27 of 63.

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