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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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New Molecular Insights for Enhancing Plant Resilience to Abiotic Stress

edited by

Aliki Kapazoglou

submission deadline 20 Oct 2026 | Viewed by 166 | Submission Open

Keywords: abiotic stress; tolerance; plant resilience; crop sustainability; environmental conditions; climate change; gene regulation; epigenetic mechanisms; microbiome

(This special issue belongs to the Section Molecular Plant Sciences)

The Role of Fatty Acids in Metabolic Disease

edited by

Danijela Ristić-Medić

and

Snježana Petrović

submission deadline 20 Oct 2026 | Viewed by 157 | Submission Open

Keywords: fatty acids; FADS; inflammation; insulin resistance; lipid mediators; lipid metabo-lism; lipotoxicity; metabolic diseases; nutrition; oxidative stress

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Advances in Plant Genomics and Genetics: 4th Edition

edited by

Hengling Wei

submission deadline 20 Oct 2026 | Viewed by 145 | Submission Open

Keywords: plant genomics; plant genetics; abiotic stresses; salt resistance; genome; next-generation sequencing

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Microbiology in the Omics Era: Genomics, Metagenomics and Computational Insights

edited by

Fei Liu

submission deadline 23 Oct 2026 | 2 articles | Viewed by 13037 | Submission Open

Keywords: microbial genomics; metagenomics; computational biology; antimicrobial resistance; host–microbe interactions; multi-omics integration; bioinformatics tools; machine learning in microbiology

(This special issue belongs to the Section Molecular Microbiology)

Latest Advances in Oxidative Stress and Brain Injury

edited by

Vittorio Fineschi

submission deadline 23 Oct 2026 | 2 articles | Viewed by 12722 | Submission Open

Keywords: measurement of ROS; pathology of brain injuries; traumatic brain injuries; hypoxic–ischemic brain damage; experimental models of brain injury; targeted therapy of brain injuries; drug abuse and ROS; histological diagnosis of brain injuries; epigenetics of brain injuries; miRNA and prognosis of neural damage; novel approaches and proofs of principle in therapy; quality of life after brain injury

(This special issue belongs to the Section Molecular Neurobiology)

Molecular and Neuromuscular Mechanisms in Skeletal Muscle Aging, 2nd Edition

edited by

Rosa Mancinelli

submission deadline 23 Oct 2026 | 5 articles | Viewed by 12449 | Submission Open

Keywords: aging; sarcopenia; neuromuscular junction; molecular muscle modifications; myokines

(This special issue belongs to the Section Molecular Biology)

Antioxidants: The Molecular Guardians Against Oxidative Stress

edited by

Karolina A. Wojtunik-Kulesza

submission deadline 23 Oct 2026 | 5 articles | Viewed by 10861 | Submission Open

Keywords: antioxidant; free radical; oxidative stress; essential oils; secondary plant metabolites

(This special issue belongs to the Section Biochemistry)

Eye Diseases: From Pathophysiology to Novel Therapeutic Approaches

edited by

Tomasz Chorągiewicz

and

Joanna Dolar-Szczasny

submission deadline 23 Oct 2026 | 5 articles | Viewed by 10667 | Submission Open

Keywords: eye diseases; genetic; biochemical; proteomic; cellular and physiological level; innovative therapeutic approaches

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Role of Natural Products in Inflammation

edited by

Antonia Cianciulli

submission deadline 23 Oct 2026 | 3 articles | Viewed by 8149 | Submission Open

Keywords: inflammation; natural products; immunomodulation; bioactive compounds; drug discovery; drug target identification; anti-inflammatory activity; antioxidant activity; cellular signalling pathways

(This special issue belongs to the Section Molecular Pharmacology)

Recent Research on Biomimetic Chromatography, QSAR and Chemoinformatics in Molecular Modeling and Drug Design

edited by

Małgorzata Janicka

submission deadline 23 Oct 2026 | 5 articles | Viewed by 8146 | Submission Open

Keywords: biomimetic chromatography; QSARs; QRARs; molecular modelling; chemoinformatics; pharmacokinetics

(This special issue belongs to the Section Molecular Informatics)

Osteoimmunology: Interactions of the Bone and Immune System

edited by

Galliera Emanuela Rita

submission deadline 23 Oct 2026 | 2 articles | Viewed by 7821 | Submission Open

Keywords: osteoimmunology markers; bone infection; inflammation and bone; immune response and bone; diagnostic and prognostic markers; bone remodeling; osteoclasts; immune-mediated bone diseases; bone–immune interface

(This special issue belongs to the Section Molecular Immunology)

Radiobiology—New Advances

edited by

Marco Calvaruso

and

Luigi Minafra

submission deadline 23 Oct 2026 | 3 articles | Viewed by 6104 | Submission Open

Keywords: radiobiology; radiotherapy; radiosensitizing agents; radioresistance; DNA damage; FLASH radiotherapy; particle therapy

(This special issue belongs to the Section Molecular Biology)

Molecular Research and Applications of Nanomaterials

edited by

Sónia Carabineiro

submission deadline 23 Oct 2026 | 4 articles | Viewed by 5708 | Submission Open

Keywords: molecular research; application; functionality of nanomaterials; catalysis; environmental science

(This special issue belongs to the Section Molecular Nanoscience)

Antifungal Potential of Botanical Compounds

edited by Francisca Sempere-Ferre

submission deadline 23 Oct 2026 | 2 articles | Viewed by 5668 | Submission Open

Keywords: botanical compounds; antifungal agents; natural products; secondary metabolites; fungal growth inhibition; bioactive plant extracts; eco-friendly antifungals; natural product chemistry; sustainable antifungal solutions; plant-derived bioactives

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Inflammatory Bowel Disease: Molecular Insights—2nd Edition

edited by

Belal Chami

submission deadline 23 Oct 2026 | 4 articles | Viewed by 4094 | Submission Open

Keywords: genomic sequencing; microbiome; dysbiosis; commensal flora; omics; immunobiology; colitis; Crohn’s disease; ulcerative colitis; multiomics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Research on Alloy Materials Microstructure and Their Functionalization

edited by

Ozkan Gokcekaya

and Celaletdin Ergun

submission deadline 23 Oct 2026 | 2 articles | Viewed by 3674 | Submission Open

Keywords: alloy design; microstructure; production methods; additive manufacturing; sol–gel process; biofunctional materials; magnetic properties; nanoparticles; ceramics; composites

(This special issue belongs to the Section Materials Science)

Molecular Advancements in Functional Materials

edited by

Joanna Karasiewicz

submission deadline 23 Oct 2026 | 5 articles | Viewed by 3261 | Submission Open

Keywords: synthesis of specialty compounds; specialty compounds in functional materials; special applications: self-cleaning, anti-icing, self-healing, biocidal, etc., properties; special-purpose functional materials

(This special issue belongs to the Section Materials Science)

Trace Elements, Metals and Bioactive Compounds: Homeostasis and Metabolic Impairment

edited by

Graziantonio Lauria

and

Rosita Curcio

submission deadline 23 Oct 2026 | 1 articles | Viewed by 3195 | Submission Open

Keywords: trace elements; bioactive compounds; metals; human health; human diseases

(This special issue belongs to the Section Biochemistry)

Molecular Research Advances in Common and Rare Pediatric Diseases

edited by

Lǎcrǎmioara Ionela Butnariu

submission deadline 23 Oct 2026 | 3 articles | Viewed by 3128 | Submission Open

Keywords: pediatric diseases; diagnosis; therapeutic targets; molecular mechanisms; pediatric pathology; signaling pathways

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms of Plant Adaptation to Stress

edited by Yuanchun Ma

submission deadline 23 Oct 2026 | 5 articles | Viewed by 2979 | Submission Open

Keywords: plant; environmental stresses; signaling pathways; stress-responsive genes; transcription factors; phytohormones; crop resilience; breeding; genetic engineering

(This special issue belongs to the Section Molecular Plant Sciences)

AI and Machine Learning in Molecular Biomarker Discovery and Mechanisms of Neurodegenerative Disorders

edited by

Seyed Ehsan Saffari

submission deadline 23 Oct 2026 | 2 articles | Viewed by 2638 | Submission Open

Keywords: artificial intelligence (AI); machine learning (ML); biomarker discovery; neurodegenerative disorders; Alzheimer’s disease (AD); Parkinson’s disease (PD); dementia; risk prediction models; multi-omics integration; translational bioinformatics

(This special issue belongs to the Section Molecular Neurobiology)

Cancer Progression and Therapeutic Resistance Mechanisms

edited by

Fabrizio Fontana

submission deadline 23 Oct 2026 | 1 articles | Viewed by 2604 | Submission Open

Keywords: cancer drug resistance; growth factors; DNA repair; miRNAs; ABC transporters; cancer stem cells; extracellular vesicles; circulating cancer cells; circulating cancer DNA; liquid biopsies; natural anticancer compounds

(This special issue belongs to the Section Molecular Oncology)

Molecular Mechanisms of Hematologic Disorders

edited by

Valentina Giudice

submission deadline 23 Oct 2026 | 2 articles | Viewed by 2178 | Submission Open

Keywords: solid tumors; hematologic disorders; hematology; bone marrow failure; leukemia; myeloma

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Design and Functional Applications of Polysaccharide Composites

edited by

Magdalena Krystyjan

Gohar Khachatryan

and

Karen Khachatryan

submission deadline 23 Oct 2026 | 1 articles | Viewed by 1460 | Submission Open

Keywords: polysaccharide composites; molecular design; functional applications

(This special issue belongs to the Section Materials Science)

Advances in the Role of Retinoic Acid-Regulated Genes in Cancer Biology

edited by Fuming Tsai

submission deadline 23 Oct 2026 | 2 articles | Viewed by 1447 | Submission Open

Keywords: retinoic acid; retinoic acid receptors; retinoic x receptors; tumorigenesis; metastasis; tumor microenvironment; molecular pathways

(This special issue belongs to the Section Molecular Genetics and Genomics)

Targeted Therapy for Breast and Gynecological Cancer

edited by Moira Ragazzi and Elisa Gasparini

submission deadline 23 Oct 2026 | 2 articles | Viewed by 1403 | Submission Open

Keywords: breast cancer; gynecological cancer; target therapy; biomarkers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Metabolic–Epigenetic Interplay in Health and Diseases

edited by

Ana Paula De Souza

submission deadline 23 Oct 2026 | 1 articles | Viewed by 1052 | Submission Open

Keywords: epigenetics; metabolism; TCA cycle; one-carbon cycle; aging; longevity; cancer; metabolic syndrome; neurodegeneration

(This special issue belongs to the Section Molecular Neurobiology)

Statin Induced Neurotoxicity

edited by

Iain P. Hargreaves

and

Adam P. Lightfoot

submission deadline 23 Oct 2026 | Viewed by 617 | Submission Open

Keywords: mitochondrial dysfunction; oxidative stress; coenzyme Q10; simvastatin; neurotoxicity; blood brain barrier

(This special issue belongs to the Section Molecular Neurobiology)

The Immune Regulation of Osteoclasts

edited by

J. Kelly Smith

submission deadline 23 Oct 2026 | Viewed by 597 | Submission Open

Keywords: hematopoietic stem cells; osteoclasts; osteoblasts; osteocytes; stromal cells; T cells; B cells; macrophages; dendritic cells; interleukins; cytokines

(This special issue belongs to the Section Molecular Immunology)

The Structure, Function, and Application of Zinc Finger Proteins

edited by

Sabrina Esposito

submission deadline 23 Oct 2026 | Viewed by 532 | Submission Open

Keywords: zinc finger proteins: structure, function and properties, applications; protein folding and dynamics; environmental contaminants and metal ions exposure, uptake, toxicity; molecular recognition and signal transduction; mechanisms of action and effects of abnormal zinc finger proteins on human health; zinc finger proteins as drug targets

(This special issue belongs to the Section Molecular Biology)

Nanotechnology for Food Science—Innovations and Sustainable Solutions

edited by

Nan Cheng

submission deadline 23 Oct 2026 | Viewed by 507 | Submission Open

Keywords: nanotechnology; nanomaterial synthesis; food safety; food science; nano-engineered food additives; nano-sensors

(This special issue belongs to the Section Molecular Nanoscience)

Autophagy: Novel Insights from Molecular and Chemical Biology

edited by

Prashant R Bharadwaj

submission deadline 23 Oct 2026 | Viewed by 480 | Submission Open

Keywords: Alzheimer’s disease; amyloid precursor protein; amyloid-β protein; protein aggregation; intracellular clearance pathways; autophagy–lysosomal pathway; ubiquitin-proteasome system; small molecule drugs; autophagy modulators, drug development

(This special issue belongs to the Section Molecular Biophysics)

Advances in Aging and Alzheimer’s Disease Research: From Molecular Mechanisms to Therapeutics—2nd Edition

edited by Lilach Soreq

submission deadline 23 Oct 2026 | Viewed by 423 | Submission Open

Keywords: aging; Alzheimer’s disease; bioinformatics; RNA-seq; Parkinson’s disease

(This special issue belongs to the Section Molecular Neurobiology)

Prostate Cancer: Molecular Mechanisms and Targeting

edited by

Guoliang Li

submission deadline 23 Oct 2026 | Viewed by 417 | Submission Open

Keywords: prostate cancer; androgen receptor; therapy resistance; epigenetics; tumor microenvironment; molecular signaling; precision oncology

(This special issue belongs to the Section Molecular Oncology)

Nanomaterials in Biomedicine, Microbiology and Tissue Engineering

edited by

Justyna Rewak-Soroczynska

submission deadline 23 Oct 2026 | Viewed by 272 | Submission Open

Keywords: nanomaterials; nanotechnology; biomedicine; microbiology; tissue regeneration

(This special issue belongs to the Section Materials Science)

Microbial Enzymes for Biotechnological Applications: 2nd Edition

edited by

Salvatore Fusco

submission deadline 25 Oct 2026 | 5 articles | Viewed by 21481 | Submission Open

Keywords: microbial enzymes; whole-cell biocatalysts; extremozyme; enzyme assays; protein engineering

(This special issue belongs to the Section Biochemistry)

Biochemical Perspectives on Diabetes

edited by

Antonio Maria Labate

submission deadline 25 Oct 2026 | 1 articles | Viewed by 923 | Submission Open

Keywords: diabetes; biochemistry; biomarkers; insulin resistance; cardiometabolic risk; inflammation; oxidative stress; diabetic complications

(This special issue belongs to the Section Biochemistry)

Research Progress on Neuroinflammation

edited by Abhishek Jauhari

submission deadline 25 Oct 2026 | Viewed by 379 | Submission Open

Keywords: neuroinflammation; mitochondria; microglia; inflammasome; cGAS; STING

(This special issue belongs to the Section Molecular Neurobiology)

Advances in Macromolecular Drug Design and Research

edited by

Harshavardhan Reddy Kasireddy

submission deadline 25 Oct 2026 | Viewed by 231 | Submission Open

Keywords: macromolecular drug design; polymer therapeutics; nanomedicine; bioconjugation; antibody–drug conjugates; peptide therapeutics; nucleic acid delivery; targeted drug delivery; controlled release; translational therapeutics

(This special issue belongs to the Section Molecular Pharmacology)

Advances in Molecular Mechanisms of Inflammatory Skin Diseases

edited by Xuming Mao

submission deadline 25 Oct 2026 | Viewed by 184 | Submission Open

Keywords: inflammatory skin diseases; dermatitis; psoriasis; inflammation

(This special issue belongs to the Section Molecular Immunology)

Molecular Mechanism in Corrosion

edited by

Yuli Panca Asmara

submission deadline 28 Oct 2026 | 1 articles | Viewed by 843 | Submission Open

Keywords: molecular corrosion mechanisms; microbiologically influenced corrosion (MIC); biofilm formation on metal surfaces; electrochemical–biological coupling; biocorrosion pathways; molecular adsorption of corrosion inhibitors; enzymatic corrosion processes; surface passivation and biofilm dynamics; molecular modeling of corrosion; microbial community analysis; corrosion protection; high temperature corrosion; corrosion in oil and gas industries; reinforced steel bar corrosion

(This special issue belongs to the Section Materials Science)

Circulating Molecular Markers and Redox Signaling in Endocrine Disorders

edited by Antonio Mancini and

Andrea Silvestrini

submission deadline 28 Oct 2026 | 2 articles | Viewed by 825 | Submission Open

Keywords: antioxidant defense; metabolic syndrome; endocrine disorders; redox signaling; circulating biomarkers

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Molecular Mechanisms and Intervention Strategies in Cardiovascular and Cerebrovascular Diseases

edited by Rossana Scuri

submission deadline 28 Oct 2026 | Viewed by 157 | Submission Open

Keywords: cardiovascular diseases; cerebrovascular diseases; therapeutic interventions; regenerative medicine; endothelial dysfunction; cardiac remodeling

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Melanin Pigmentation: Physiology and Pathology

edited by

Shosuke Ito

and

Manickam Sugumaran

submission deadline 30 Oct 2026 | 10 articles | Viewed by 18635 | Submission Open

Keywords: eumelanin; pheomelanin; melanogenesis; photoprotection; pigmentary disorders; depigmenting agents; extracutaneous melanins

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Updates and Advances in the Field of Glioblastomas: Mechanisms, Microenvironment and Treatments

edited by

Samantha Epistolio

submission deadline 30 Oct 2026 | 8 articles | Viewed by 11004 | Submission Open

Keywords: GBM; molecular classification; pediatric diffuse gliomas; signaling pathways in GBMs; recurrent gliomas; midbrain gliomas; immunotherapy; targeted therapies for GBMs

(This special issue belongs to the Section Molecular Oncology)

Molecular Research in Skin Health and Disease

edited by

Mihaela Pertea

submission deadline 30 Oct 2026 | 3 articles | Viewed by 7527 | Submission Open

Keywords: wound healing; molecular research in skin lesions; dermatologic surgery; cosmetic surgery; exosomes: new molecular targets of diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular and Cellular Therapeutics for Respiratory Diseases

edited by

Roberto Plebani

submission deadline 30 Oct 2026 | 2 articles | Viewed by 7013 | Submission Open

Keywords: lung diseases; cystic fibrosis; chronic obstructive pulmonary disease; asthma; drug delivery

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Microbial Genomics: Insights from Whole Genomes and Metagenomes

edited by

Marcos Quintela Baluja

submission deadline 30 Oct 2026 | 5 articles | Viewed by 5888 | Submission Open

Keywords: microbial evolution; whole-genome sequencing; metagenomics; horizontal gene transfer; antimicrobial resistance; computational genomics

(This special issue belongs to the Section Molecular Genetics and Genomics)

The Impact of Oxidative Stress on Male and Female Germ Cells: From Redox Biology to Photon Emission

edited by

József Bódis

, Kálmán András Kovács and

Ilya Volodyaev

submission deadline 30 Oct 2026 | 1 articles | Viewed by 5885 | Submission Open

Keywords: oxidative stress; germ cells; fertility; redox signaling; mitochondrial dynamics; DNA damage; photonic communication; ultra-weak photon emission; quantum biology; reproductive health

(This special issue belongs to the Section Biochemistry)

Molecular Insights into Role of Anthranilic Acid in Neuropsychiatric Diseases

edited by

Gregory F. Oxenkrug

submission deadline 30 Oct 2026 | 2 articles | Viewed by 5460 | Submission Open

Keywords: anthranilic acid; Alzheimer’s disease; autism; schizophrenia; bipolar disorder; major depressive disorder; post-partum depression; COVID-19; interferons; attention deficit disorder; cognitive impairment; G-protein-coupled receptor 109A; microbiome; gut–brain axis

(This special issue belongs to the Section Molecular Neurobiology)

Displaying special issue 1301-1350 on page 27 of 64.

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