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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Molecular and Physiological Responses of Insects to Biotic, Abiotic and Xenobiotic Constraints

edited by

Farman Ullah

Shuo Yan

and Yaobin Lu

submission deadline 20 Oct 2025 | 3 articles | Viewed by 1708 | Submission Open

Keywords: climatic changes; chemical insecticides; insect adaptation mechanisms; resistance mechanisms; ecosystem services; insect ecology; thermal stress adaptations

(This special issue belongs to the Section Molecular Biology)

New Insights into Airway Smooth Muscle: From Function to Dysfunction

edited by

Hiroaki Kume

submission deadline 20 Oct 2025 | 2 articles | Viewed by 1664 | Submission Open

Keywords: contraction; proliferation; migration; airway hyperresponsiveness; airway remodeling; β 2-adrenergic receptors; muscarinic receptor; Th2 inflammation; non-Th2 inflammation; oxidative stress; lysophospholipids; intracellular signal transduction processes; Ca2+ signaling; interactions with other cells (inflammatory cells and epithelium); asthma; COPD

(This special issue belongs to the Section Molecular Biology)

Molecular Research and Insight into Endocannabinoid System

edited by

Jorge Manzanares

and

Francisco Navarrete

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1645 | Submission Open

Keywords: endocannabinoid system; molecular research; biomarker; translational

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Insights into Microbial Dynamics in Agroforestry for Resilience and Climate Adaptation

edited by

Amrita Chakraborty

and

Amit Roy

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1644 | Submission Open

Keywords: agroforestry; soil microbes; plant-microbe interactions; microbial influence; microbiomes; insect-microbe interactions; horizontal gene transfer

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Perspective in Autoimmune Diseases

edited by Andrés González-García and

Montserrat Fernández-Guarino

submission deadline 20 Oct 2025 | 2 articles | Viewed by 1606 | Submission Open

Keywords: interferon; cytokines; lupus nephritis; lupus; type I interferon; vasculitis; IgG4-related disease; B cell; NETs; IL-6; biomarkers

(This special issue belongs to the Section Molecular Immunology)

The Role of Iodinated Compounds and Molecular Iodine in Human Disease

edited by

Carmen Aceves

submission deadline 20 Oct 2025 | 2 articles | Viewed by 1594 | Submission Open

Keywords: iodine; iodinated compounds; oxidized iodine; oxidized iodine supplement

(This special issue belongs to the Section Biochemistry)

Advanced Molecular Research in Benign and Malignant Lung Disease

edited by Biniam Kidane

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1575 | Submission Open

Keywords: benign lung disease; lung cancer; molecular biology; inflammation; metastasis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Prostate Diseases: Focus on Hormone Therapies and Targeted Interventions

edited by Gabriel Campolina-Silva and Héctor Contreras

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1511 | Submission Open

Keywords: urinary disease; prostate cancer; hormone; therapeutic strategy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances and Insights in Tumorigenesis and Tumor Metastasis

edited by

Sayem Miah

and

Mohammad Rahman

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1493 | Submission Open

Keywords: tumorigenesis; metastasis; biomarkers

(This special issue belongs to the Section Molecular Oncology)

Microbiome Connections in Age-Related Diseases

edited by Shalini Jain

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1441 | Submission Open

Keywords: microbiome; aging; age-related diseases; Alzheimer’ s; dementia

(This special issue belongs to the Section Molecular Microbiology)

Latest Review Papers in Physical Chemistry and Chemical Physics 2024

edited by

Victor Borovkov

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1428 | Submission Open

Keywords: heterogeneous structures; alignment and surface phenomena; quantum theory; statistical and classical mechanics; molecular structure; chemical kinetics; dynamics; kinetics; photochemistry; spectroscopy

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Novel Insights into Microglia Heterogeneity and Neurodegeneration

edited by

Maria Anttonietta Panaro

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1405 | Submission Open

Keywords: microglia; synapses; stress; aging; heterogeneity; CNS; single-cell RNA sequencing; neurodegenerative diseases

(This special issue belongs to the Section Molecular Neurobiology)

Systemic and Mucosal Inflammation in Colorectal Cancer: Underlying Factors, Significance, and Related Biomarkers, 2nd Edition

edited by

Paola Sena

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1401 | Submission Open

Keywords: molecular changes; colorectal cancer; normal mucosa; apoptotic proteins; inflammatory mechanism; adenoma– carcinoma sequence; cancer biomarkers

(This special issue belongs to the Section Molecular Oncology)

Molecular Perspectives on the Synthesis and Application of Hydrogel Materials

edited by

Jieping Fan

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1395 | Submission Open

Keywords: hydrogels; molecular basis; polymeric networks; supermolecular chemistry; three-dimensional structure; mechanical strength; rheologic properties; biomaterial

(This special issue belongs to the Section Materials Science)

Biomaterials and Therapeutics for Pulp-Dentin Complex Regeneration

edited by

Paulo J. Palma

and

Marco C. Bottino

submission deadline 20 Oct 2025 | Viewed by 1362 | Submission Open

Keywords: biomaterials; dental materials; regenerative dentistry; pulp regeneration scaffolds; tissue engineering

(This special issue belongs to the Section Materials Science)

Complications of Pregnancy: The Importance of Omics-Based Diagnosis and Therapeutic Approaches

edited by

Alejandra Garcia-Gasca

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1340 | Submission Open

Keywords: pregnancy complications; epigenetics; omics; miRNA-based therapies; microbiome analysis; early diagnosis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Research on Chronic Kidney Disease

edited by

Sohel Julovi

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1304 | Submission Open

Keywords: CKD; CVD; CKD-MBD; oxidative stress; inflammation; fibrosis; biochemical markers

(This special issue belongs to the Section Molecular Biology)

New Molecular Mechanisms of Genotoxicity

edited by Francesca Marcon and

Roberta Meschini

submission deadline 20 Oct 2025 | Viewed by 1240 | Submission Open

Keywords: DNA damage; DNA repair; genotoxicity; carcinogenesis; chronic degenerative diseases; human health; molecular mechanisms

(This special issue belongs to the Section Molecular Toxicology)

Molecular Research in Epilepsy

edited by

Kinga Borowicz

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1177 | Submission Open

Keywords: epilepsy; epileptogenesis; antiepileptic drugs; drug resistance; interactions of antiepileptic drugs; multi-omics in epilepsy

(This special issue belongs to the Section Molecular Neurobiology)

Functional Nanomaterials and Nanocomposites for Biomedical Application

edited by Gi Doo Cha

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1163 | Submission Open

Keywords: nanomaterials; nanocomposites; biomedicine; metal nanoparticles; drug delivery; bioelectronics

(This special issue belongs to the Section Molecular Nanoscience)

Stem Cells in Tissue Engineering

edited by Ichiro Takada

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1145 | Submission Open

Keywords: stem cells; transcription factors; transcription co-regulators; chromatin remodeling factors; chromatin receptors; nuclear maintenance and differentiation; iPS cells; iPS-T/NK; tissue engineering

(This special issue belongs to the Section Molecular Biology)

Advances in Cancer Stem Cells and Tumor Microenvironment

edited by Shaoguang Li

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1132 | Submission Open

Keywords: cancer stem cells; tumor microenvironment; tumor initiation; tumor progression; chemoresistance

(This special issue belongs to the Section Molecular Oncology)

Next-Gen Tissue Engineering in Disease Modelling, Drug Discovery and Immunotherapeutics

edited by

Hugo Ronaldo Freitas Caires

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1125 | Submission Open

Keywords: tissue engineering; 3D cell culture; biomaterials; disease modelling; immunotherapy; cell-based therapies; organ-on-a-chip

(This special issue belongs to the Section Molecular Biology)

The Molecular Basis of Extracellular Vesicles in Health and Diseases—2nd Edition

edited by Taral R. Lunavat

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1119 | Submission Open

Keywords: exosomes; microvesicles; extracellular vesicles; genetic material; therapeutics; diagnostics; biomarkers; molecular pathway; liquid biopsy; metabolism; omics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Studies of Muscle Contraction

edited by

Massimo Reconditi

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1082 | Submission Open

Keywords: muscle contraction; actin; myosin; thin and thick filament; cytoskeletal anchoring protein

(This special issue belongs to the Section Molecular Biophysics)

Advances in Kidney Transplantation

edited by Zeljko Kikic

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1063 | Submission Open

Keywords: chronic rejection; antibody-mediated rejection; immunosuppression; BK virus nephropathy (BKVAN); diagnostic challenges

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Regulation of Ion Channels and Transporters

edited by

Susumu Ohya

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1010 | Submission Open

Keywords: ion channels; ion transporters; cardiovascular disease; inflammatory disease; cancers; neurogenerative disease; disease microenvironment; drug discovery; drug resistance

(This special issue belongs to the Section Molecular Biology)

Bioactive Compounds of Natural Origin: 2nd Edition

edited by

Katarzyna Pacyga

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1010 | Submission Open

Keywords: plants; extraction methods; bioactive compounds; natural products; application

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Pathogenic Proteins in Neurodegenerative Diseases: From Pathogenesis to Therapeutic Innovations

edited by

Minseok Song

and

Nidhi Puranik

submission deadline 20 Oct 2025 | 1 articles | Viewed by 979 | Submission Open

Keywords: Alzheimer’ s disease; Parkinson’ s disease; amyotrophic lateral sclerosis; frontotemporal dementia; lewy bodies dementia; amyloid β -protein; τ -protein; α -synuclein; TDP-43; neurotransmitter; neuropeptide; protein misfolding; protein Homeostasis; neuroinflammatory proteins; post-translational modifications

(This special issue belongs to the Section Molecular Neurobiology)

New Molecular Progression of Movement Disorders

edited by

Michał Latalski

and

Pilar Gomez-Garre

submission deadline 20 Oct 2025 | 1 articles | Viewed by 972 | Submission Open

Keywords: movement disorders; molecular mechanisms; neurodegenerative diseases; therapeutic targets; biomarkers; neuroinflammation; protein misfolding; mitochondrial dysfunction; environmental factors; genetic factors

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Regulatory Mechanisms in the Hypoxic Environment

edited by Irene Filippi

submission deadline 20 Oct 2025 | 1 articles | Viewed by 957 | Submission Open

Keywords: hypoxia; hypoxia-inducible factors (HIFs); angiogenesis; metabolic adaptation; autophagy; cell survival; chronic obstructive pulmonary disease (COPD); cancer

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in the 3D Culture Systems and Organoids for Disease Modeling and Therapeutics

edited by Su-Yun Lyu

submission deadline 20 Oct 2025 | 1 articles | Viewed by 950 | Submission Open

Keywords: 3D culture systems; organoids; disease modeling; drug discovery; regenerative; medicine biomaterials; molecular mechanisms; cancer; immunology; personalized medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Multi-Omics Approaches to Disentangle Pathomechanisms in Neurological Disease

edited by

Francesco Pezzini

and

Stefano Doccini

submission deadline 20 Oct 2025 | 1 articles | Viewed by 947 | Submission Open

Keywords: neurological diseases; molecular mechanisms; neurodegeneration; omics; bioinformatics; disease biomarkers; biochemical pathways; diagnostic and therapeutic targets

(This special issue belongs to the Section Molecular Neurobiology)

Ceramides and Ceramide Kinase

edited by Antonio Gomez-Muñoz

submission deadline 20 Oct 2025 | 1 articles | Viewed by 940 | Submission Open

Keywords: cancer; cell survival; ceramides; ceramide 1-phosphate; inflammation

(This special issue belongs to the Section Biochemistry)

The Activity and Underlying Mechanisms of Anticancer Drugs

edited by Vilma Petrikaitė

submission deadline 20 Oct 2025 | 1 articles | Viewed by 939 | Submission Open

Keywords: anticancer drugs; molecular mechanisms of drug action; drug resistance; novel targeted therapies

(This special issue belongs to the Section Molecular Pharmacology)

Challenges of Acute Ischemic Stroke

edited by

Marta Iacobucci

submission deadline 20 Oct 2025 | 1 articles | Viewed by 882 | Submission Open

Keywords: stroke; endovascular treatment; intravenous thrombolysis; futile recanalization; microvascular therapy

(This special issue belongs to the Section Molecular Neurobiology)

Translational Research in Angiogenesis—a Key Tool for Developing Therapeutic Strategies Towards Tissue Regeneration

edited by Ektoras Hadjipanayi

submission deadline 20 Oct 2025 | 1 articles | Viewed by 824 | Submission Open

Keywords: angiogenesis; wound bed; stromal microenvironment; stem cells; tissue repair; hypoxia; growth factors; molecular signaling

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

COVID-19: Molecular Research and Novel Therapy

edited by

Mihaela Chivu-Economescu

submission deadline 20 Oct 2025 | 1 articles | Viewed by 820 | Submission Open

Keywords: SARS-CoV-2; virus-host interaction; immune response; antiviral agents; vaccines

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Yeast Modeling in Metabolism and Cell Cycle Research

edited by

Teodora Emilia Coldea

submission deadline 20 Oct 2025 | Viewed by 790 | Submission Open

Keywords: yeast modeling; metabolism; cell cycle development; microbial fermentation; bioactive compounds; probiotics; drug targets

(This special issue belongs to the Section Molecular Biology)

Synthesis Manufacturing and Biomedical Applications of Nanofibers Scaffold

edited by

Marco Antonio Álvarez Pérez

and

Vincenzo Guarino

submission deadline 20 Oct 2025 | 1 articles | Viewed by 772 | Submission Open

Keywords: scaffold manufacturing; nanofibers; 3D platforms; biohybrid scaffolds; biomolecules; functionalization; biomaterials

(This special issue belongs to the Section Molecular Nanoscience)

New Insights into Kidney Diseases—2nd Edition

edited by

Kan Katayama

submission deadline 20 Oct 2025 | 1 articles | Viewed by 749 | Submission Open

Keywords: kidney disease; focal segmental glomerulosclerosis; genetic kidney disease; minimal change disease; nephrotic syndrome; podocyte

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Sepsis: Pathogenesis, Biomarkers, Treatments and Prognosis

edited by Francesca Innocenti

submission deadline 20 Oct 2025 | 2 articles | Viewed by 744 | Submission Open

Keywords: sepsis phenotypes; hemodynamic stabilization; fluids; vasopressors; diagnostic biomarkers; tailored approach; immune modulation; immunomodulatory therapy; prognostic stratification

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Insights into Addiction

edited by

Aleksandra Suchanecka

and

Jolanta Chmielowiec

submission deadline 20 Oct 2025 | 1 articles | Viewed by 724 | Submission Open

Keywords: addiction; dependence; neurobiology; reward; neuroplasticity; biostatistics

(This special issue belongs to the Section Molecular Neurobiology)

Uncovering the Basis of Plant Nutrient Uptake, Interactions and Homeostasis: Molecular Mechanisms and Their Applications

edited by

Alessio Aprile

submission deadline 20 Oct 2025 | Viewed by 656 | Submission Open

Keywords: nutrient transport; homeostasis; nutrient signaling and pathways; nitrogen use efficiency; acronutrients; micronutrients; plant nutrition

(This special issue belongs to the Section Molecular Plant Sciences)

Correlation Between Oxidative Stress and Inflammation

edited by Margarete Dulce Bagatini

submission deadline 20 Oct 2025 | Viewed by 528 | Submission Open

Keywords: autoimmune diseases; neurodegenerative diseases; purinergic system; inflammatory processes and oxidative stress

(This special issue belongs to the Section Biochemistry)

Advanced Research on the Detection of Small Metabolites in Biological Fluids

edited by

Stefania Garzoli

submission deadline 20 Oct 2025 | Viewed by 528 | Submission Open

Keywords: metabolomic; biological fluids; GC/MS; HPLC/MS; NMR

(This special issue belongs to the Section Molecular Biology)

Molecular Insights into Pediatric Brain Tumors: Unraveling the Complexity of Pathogenesis and Identifying New Therapeutic Targets

edited by Xiao-Nan Li and Holly Lindsay

submission deadline 20 Oct 2025 | Viewed by 518 | Submission Open

Keywords: brain tumor; pediatric tumor biology; molecular subtyping; radiation therapy; genetic and epigenetic abnormalities; tumorigenesis investigation; targeted therapy; diagnostic markers; therapy resistance; tumor relapse

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Current Insights for the Development of Emerging Photovoltaics Through Molecular Research

edited by

Dimitris A. Chalkias

Elias Stathatos

and

Aikaterini K. Andreopoulou

submission deadline 20 Oct 2025 | Viewed by 507 | Submission Open

Keywords: molecular photovoltaics; perovskite solar cells; quantum dot solar cells; organic solar cells; dye-sensitized solar cells; molecular design and engineering; molecular semiconductors

(This special issue belongs to the Section Materials Science)

Role of Cortex in Health and Disease

edited by Valentina Licheri

submission deadline 20 Oct 2025 | Viewed by 489 | Submission Open

Keywords: neurodevelopmental disorder; corticogenesis; molecular mechanisms; cognitive deficits; behavioral deficits

(This special issue belongs to the Section Molecular Neurobiology)

Ribonucleotides in Genomic DNA: Molecular Mechanisms and Biological Implications

edited by

Francesca Storici

submission deadline 20 Oct 2025 | Viewed by 472 | Submission Open

Keywords: ribonucleotides in DNA; genomic RNA incorporation; ribonucleotide excision repair; ribonucleotide reductase; genome stability; function of ribonucleotides in DNA; DNA polymerase fidelity; ribonucleotide-induced mutations; ribonucleotide misincorporation; ribonucleotide in DNA structure

(This special issue belongs to the Section Molecular Biology)

Displaying special issue 1251-1300 on page 26 of 68.

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