Complications of Pregnancy: The Importance of Omics-Based Diagnosis and Therapeutic Approaches
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 20 October 2025 | Viewed by 2908
Special Issue Editor
Interests: developmental biology; congenital malformations; epigenetic regulation; sex determination
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
I am currently organizing a Special Issue entitled “Complications of Pregnancy: The Importance of Omics-Based Diagnosis and Therapeutic Approaches” in collaboration with the International Journal of Molecular Sciences (IF: 5.6, ISSN 1422-0067, https://www.mdpi.com/journal/ijms).
Pregnancy complications are physical or mental medical conditions that affect the health of pregnant or post-partum women, their babies, or both. Complications may arise from preexisting conditions or may first develop during pregnancy. Early detection and timely treatment can help reduce the risk of serious outcomes. Complications during pregnancy can occur for several reasons; some common complications include, but are not limited to:
- Ectopic pregnancy
- Miscarriage
- Congenital disorders
- Preeclampsia
- Gestational diabetes
- Preterm labor
- Infections
- Placenta previa
- Depression
- Anemia
Most medications are not tested for use during pregnancy, and health care providers may decide to treat the condition with available medications or not to treat it at all, depending on the benefit/risk factor. Prevention, early detection, and new alternative therapies based, for example, on epigenetic approaches or microbiome analysis become relevant in the context of pregnancy and require priority in research and development. Suggested topics may include:
- Omics-based studies for detection and treatment of pregnancy complications
- Novel or improved tools for early diagnosis
- Epigenetic markers
- Epigenetic and miRNA-based therapies
- Alterations of the microbiome (gut/fecal, vaginal, endometrial, etc.) and relevance for diagnosis or treatment
Thus, this Special Issue of the International Journal of Molecular Sciences aims to bring together high-quality articles that address different areas within pregnancy complications. We welcome all researchers working on prevention, diagnosis, and therapies for different pregnancy conditions to contribute with in-depth critical reviews and original articles. Contributions from international investigators will provide a comprehensive state-of-the-art analysis of pregnancy complications to help implement better prevention and management strategies.
Dr. Alejandra Garcia-Gasca
Guest Editor
Manuscript Submission Information
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Keywords
- pregnancy complications
- epigenetics
- omics
- miRNA-based therapies
- microbiome analysis
- early diagnosis
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