Regulation of Ion Channels and Transporters
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 20 October 2025 | Viewed by 651
Special Issue Editor
Interests: molecular pharmacological study of ion channel related diseases
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Ion channels and ion transporters play crucial roles in regulating cellular ion homeostasis and signaling. Their dysfunction contributes to a variety of diseases, including neurological, cardiovascular, immune, and metabolic diseases and cancers. Understanding the mechanisms by which ion channels and transporters operate and malfunction can provide insights into disease pathogenesis and identify potential therapeutic targets.
This Special Issue will bring together recent advances in the pivotal functions of ion channels and transporters in health and disease, highlighting their significance in treatment development. Basic medical research on this topic is also welcome.
Topics to address:
- Ion channels and transporters as targets for a variety of diseases;
- Modulation of intracellular signaling pathways mediating ion channels and transporters, focusing in particular on K+, Cl−, and Mg2+;
- Transcriptional and post-transcriptional regulation mediating ion channels and transporters;
- Novel roles of ion channels and transporters in disease microenvironments (i.e., regulation of cytokines/chemokines recruiting immunosuppressive cells in the tumor microenvironment);
- Roles of ion channels and transporters in the acquisition and overcoming of drug resistance;
- Innovative methods measuring the concentration of ions in living cells.
Prof. Dr. Susumu Ohya
Guest Editor
Manuscript Submission Information
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Keywords
- ion channels
- ion transporters
- cardiovascular disease
- inflammatory disease
- cancers
- neurogenerative disease
- disease microenvironment
- drug discovery
- drug resistance
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