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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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New Insights in Tumor Immunity

edited by

George Sharonov

submission deadline 20 Apr 2026 | 10 articles | Viewed by 33827 | Submission Open

Keywords: tumor immunity; tumor evolution; tumor antigens; immune surveillance; cancer immunoediting; tumor microenvironment; immunotherapies; immune checkpoints; tumor-specific lymphocytes

(This special issue belongs to the Section Molecular Immunology)

Molecular Biology of Cancer—Implications for Diagnosis and Treatment: 3rd Edition

edited by

Stergios Boussios

Saak V. Ovsepian

and

Matin Sheriff

submission deadline 20 Apr 2026 | 16 articles | Viewed by 29402 | Submission Open

Keywords: genomics; epigenetics; translational research; oncology precision medicine

(This special issue belongs to the Section Molecular Oncology)

Recent Research in Gut Microbiota–Gut–Brain Axis

edited by Ying Han

submission deadline 20 Apr 2026 | 5 articles | Viewed by 29102 | Submission Open

Keywords: microbiota; dysbiosis; microbiota– gut– brain axis; short-chain fatty acid; immune pathway; vagus nerve; neuropsychiatric disorders; depression

(This special issue belongs to the Section Molecular Biology)

Molecular and Physiological Mechanisms of Exercise

edited by Zoran Nikolovski

submission deadline 20 Apr 2026 | 3 articles | Viewed by 17448 | Submission Open

Keywords: molecular biology; biochemistry and exercise; athletic performance; multi-omic

(This special issue belongs to the Section Molecular Biology)

Molecular Mechanisms of Tendinopathy: Unraveling the Pathogenesis of Tendon Diseases

edited by

Pauline Po Yee Lui

submission deadline 20 Apr 2026 | 2 articles | Viewed by 17183 | Submission Open

Keywords: tendinopathy; tendon pain; stiffness; physical disability; etiopathogenesis; molecular mechanisms; tendon reattachment; tendon repair; advanced molecular tools; omics techniques; biophysical therapies; novel biomaterials

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Recent Advances in Wound Healing: 2nd Edition

edited by

Alina Maria Holban

and

Carmen Curutiu

submission deadline 20 Apr 2026 | 7 articles | Viewed by 15888 | Submission Open

Keywords: management of wounds; nanobiomaterials; infection control; chronic wounds; biofilm infections; wound dressings; tissue engineering; wound healing

(This special issue belongs to the Section Molecular Biology)

Recent Advances in Molecular Mechanisms Underlying Kidney Diseases: Pathophysiology and Therapeutic Targets, 2nd Edition

edited by

George J. Dugbartey

submission deadline 20 Apr 2026 | 6 articles | Viewed by 15215 | Submission Open

Keywords: kidney diseases; pathophysiology; molecular mechanisms; therapeutic targets; acute kidney injury; chronic kidney disease; polycystic kidney disease; end-stage renal disease; IgA nephropathy; diabetic nephropathy; hypertensive nephropathy; renal cancer; kidney infarction; kidney infection; kidney failure; kidney stones; renal tubular acidosis; renal artery stenosis; acute tubular necrosis; glomerulopathy; interstitial nephritis; nephrotic syndrome; simple kidney cyst

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Mitochondrial Dysfunction: A Metabolic, Cardiovascular, Neurodegenerative and Neuromuscular Issue: 2nd Edition

edited by

Stefano Doccini

Federica Morani

and Claudia Nesti

submission deadline 20 Apr 2026 | 5 articles | Viewed by 14300 | Submission Open

Keywords: bioenergetics; mitochondrial disorders; biomarkers; OxPhos complexes; mitochondrial DNA; aging; neurodegenerative diseases; cardiovascular diseases; metabolic diseases; therapies to counteract mitochondrial dysfunction TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian // TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back // This page is in English Translate to Simplified Chinese Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Metabolism of Ameloblasts in Tooth Development

edited by Maiko Suzuki and Yong Hee Patricia Chun

submission deadline 20 Apr 2026 | 6 articles | Viewed by 13265 | Submission Open

Keywords: ameloblasts; amelogenesis; metabolism; gene regulation; amelogenesis imperfecta; SCPP; enamel hypomineralization; tooth epithelial stem cells

(This special issue belongs to the Section Molecular Biology)

Natural Compounds for Counteracting GI and Liver Diseases

edited by

Daniela Gabbia

and

Raquel Abalo

submission deadline 20 Apr 2026 | 5 articles | Viewed by 12949 | Submission Open

Keywords: natural compounds; gastrointestinal diseases; liver diseases; pharmacological potential

(This special issue belongs to the Section Bioactives and Nutraceuticals)

New Insights into Immune Dysregulation Disorders

edited by

Francesco Saettini

submission deadline 20 Apr 2026 | 6 articles | Viewed by 12658 | Submission Open

Keywords: immune dysregulation disorders; autoimmune conditions; primary immunodeficiencies; autoinflammatory disorders

(This special issue belongs to the Section Molecular Immunology)

Pediatric Diseases: From Molecular Mechanisms to Novel Therapeutic Strategies

edited by

Elena Tarca

submission deadline 20 Apr 2026 | 5 articles | Viewed by 12541 | Submission Open

Keywords: congenital abnormalities; genetic disease; molecular mechanism; therapeutic agents; maternal and fetal medicine; pediatric diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Viruses as Therapeutic Tools: Medical and Biotechnological Applications

edited by

Víctor Romanowski

submission deadline 20 Apr 2026 | 4 articles | Viewed by 11486 | Submission Open

Keywords: molecular virology; virus– host interactions; immunology; gene therapy vectors; vaccines; antivirals

(This special issue belongs to the Section Molecular Microbiology)

Galectins (Gals), 2nd Edition

edited by

Luciano Pirone

submission deadline 20 Apr 2026 | 8 articles | Viewed by 11261 | Submission Open

Keywords: galectin; inhibitors; cancer; inflammation; glycans; drug design; modeling; biomarkers

(This special issue belongs to the Section Molecular Biology)

New Advances in Epigenetics and Epigenomics

edited by Vicki Maltby

submission deadline 20 Apr 2026 | 4 articles | Viewed by 10940 | Submission Open

Keywords: epigenetics; epigenomics; multi-omics; epitranscriptomics; single cell

(This special issue belongs to the Section Molecular Genetics and Genomics)

Boosting the Production of Bioactive Compounds: Biotechnology and Metabolic Engineering of Medicinal Plants

edited by

Katarzyna Hnatuszko-Konka

and

Izabela Grzegorczyk-Karolak

submission deadline 20 Apr 2026 | 5 articles | Viewed by 10720 | Submission Open

Keywords: bioactive compounds; plant tissue culture; elicitors; metabolic engineering; gene expression; medicinal plants; metabolic pathway; plant biotechnology

(This special issue belongs to the Section Molecular Plant Sciences)

Plant-Derived Bioactive Compounds for Pharmacological Applications

edited by

Ilian Badjakov

and

Ivayla Dincheva

submission deadline 20 Apr 2026 | 6 articles | Viewed by 10701 | Submission Open

Keywords: plant-derived bioactive compounds; pharmacological applications; antioxidant activity; anti-inflammatory agents; antimicrobial properties; neuroprotective effects; drug discovery; high-throughput screening; extraction and isolation techniques; structural characterization; CRISPR technology; genome editing; bioprocess engineering; bioreactor production; therapeutic potential; metabolite profiling

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Physiological Functions and Pathological Effects of Microglia

edited by Hiroshi Nakanishi

submission deadline 20 Apr 2026 | 4 articles | Viewed by 10264 | Submission Open

Keywords: circadian clock; homeostasis; immune response; microglia; neurodegenerative diseases; neuroinflammation; neuropsychiatric disorders; neuromodulation; phagocytosis; synaptic pruning

(This special issue belongs to the Section Molecular Neurobiology)

The Role of RNAs in Cancers: Recent Advances

edited by Roman Beňačka

submission deadline 20 Apr 2026 | 4 articles | Viewed by 9930 | Submission Open

Keywords: cancer cells; carcinogenesis; mRNAs; ncRNAs; lncRNAs; miRNAs; circRNAs; piRNAs; RNA-based diagnostics; RNA-based therapy

(This special issue belongs to the Section Molecular Oncology)

Molecular Insights in Neurodegeneration

edited by

Oscar Arias-Carrión

submission deadline 20 Apr 2026 | 5 articles | Viewed by 9805 | Submission Open

Keywords: neurodegeneration; molecular mechanisms; protein aggregation; neuroinflammation; oxidative stress; mitochondrial dysfunction; Alzheimer’ s disease; Parkinson’ s disease; biomarkers; therapeutic targets

(This special issue belongs to the Section Molecular Neurobiology)

New Insights into the Immunopathology of Autoimmune and Drug Induced Liver Injury

edited by Eleni Geladari

submission deadline 20 Apr 2026 | 2 articles | Viewed by 9666 | Submission Open

Keywords: liver disease; liver injury; immune system; immune dysregulation

(This special issue belongs to the Section Molecular Immunology)

Molecular Insight into Skin Infection and Inflammation

edited by

Danuta Nowicka

submission deadline 20 Apr 2026 | 2 articles | Viewed by 9582 | Submission Open

Keywords: skin infection; skin inflammation; inflammatory skin diseases; atopic dermatitis; skin microbiome

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Biomarkers in Cancer Immunology

edited by

Wioletta Olejarz

submission deadline 20 Apr 2026 | 3 articles | Viewed by 9507 | Submission Open

Keywords: immunotherapy; adoptive cell transfer; CAR-T cells; immune checkpoint inhibitors; tumor microenvironment; extracellular vesicles; biomarkers; miRNA; DNA

(This special issue belongs to the Section Molecular Immunology)

Editorial Board Members’ Collection Series: “Selenium and Sulfur Chemistry”

edited by

Claudio Santi

and

Narimantas K. Cenas

submission deadline 20 Apr 2026 | 3 articles | Viewed by 9393 | Submission Open

Keywords: selenium; sulfur; redox; catalysis; selenoproteins; green chemistry; materials; stereoselective synthesis

(This special issue belongs to the Section Biochemistry)

Therapeutics and Pathophysiology of Cognitive Dysfunction

edited by

Maheedhar Kodali

submission deadline 20 Apr 2026 | 3 articles | Viewed by 9150 | Submission Open

Keywords: cognition; neurologic diseases; neuroinflammation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Biomarkers, Treatments, and Clinical Outcomes for Meningiomas and Other Skull Base Tumors

edited by

Michael Graner

and Philip David Tatman

submission deadline 20 Apr 2026 | 3 articles | Viewed by 8955 | Submission Open

Keywords: skull base tumor; meningioma; biomarkers; diagnosis; prognosis; radiology; surgery; pharmacotherapy; immunology

(This special issue belongs to the Section Molecular Oncology)

Prostate Cancer Research Update: Molecular Diagnostic Biomarkers

edited by Mikhail Baryshev

submission deadline 20 Apr 2026 | 4 articles | Viewed by 8820 | Submission Open

Keywords: prostate cancer; molecular biomarkers; cancer-specific DNA methylation; non-coding genes; gene fusions; lncRNA

(This special issue belongs to the Section Molecular Oncology)

Research Advances in Reproductive Immunology

edited by

Monika Kniotek

submission deadline 20 Apr 2026 | 2 articles | Viewed by 8775 | Submission Open

Keywords: reproductive immunology; immune regulation; fertility; pregnancy; immunocontraception

(This special issue belongs to the Section Molecular Immunology)

The Role of Cytokines in Health and Diseases

edited by Hung-Jen Liu

submission deadline 20 Apr 2026 | 5 articles | Viewed by 8682 | Submission Open

Keywords: cytokines; immune regulation; disease management; signaling pathways; translational research; clinical applications

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Plant Chloroplasts and Mitochondria: Key Organelles for Sustainable Agriculture

edited by

Nunzia Scotti

submission deadline 20 Apr 2026 | 4 articles | Viewed by 8653 | Submission Open

Keywords: ‘ omics’ ; photosynthesis; energy production; crops; climate change; sustainable agriculture; stress response; inter-organelle crosstalk; signaling networks; genetic engineering

(This special issue belongs to the Section Molecular Plant Sciences)

The Role of Protein Kinase in Health and Diseases

edited by

Manuela Loi

submission deadline 20 Apr 2026 | 4 articles | Viewed by 8127 | Submission Open

Keywords: protein kinases; phosphorylation; cancer; neurological disorder; targeted therapies; metabolic diseases

(This special issue belongs to the Section Biochemistry)

Molecular Advances in Blood Disorders

edited by

Tadej Pajič

submission deadline 20 Apr 2026 | 4 articles | Viewed by 8083 | Submission Open

Keywords: acquired and inherited blood disorders; diagnostic; prognostic and predictive biomarkers; molecular profiling; molecular monitoring; targeted therapy; leukaemia; lymphoma; disorders of haemostasis and thrombosis; genetic predisposition; germline pathogenic variants; molecular mechanisms; (epi)genomics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Pathophysiology and Pharmacology in Psychiatry

edited by

Galila Agam

submission deadline 20 Apr 2026 | 3 articles | Viewed by 8032 | Submission Open

Keywords: psychiatric disorders; mental health; pathophysiology; neuropsychopharmacology; brain

(This special issue belongs to the Section Molecular Neurobiology)

Gynecologic Oncology: Molecular Mechanisms and Therapies

edited by

Angel Yordanov

submission deadline 20 Apr 2026 | 3 articles | Viewed by 7856 | Submission Open

Keywords: cervical cancer; endometrial cancer; ovarian cancer; vulvar cancer; carcinogenesis; microinvairment; immunotherapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Recent Progress in Molecular Mechanisms of Sperm Metabolism and Development

edited by Karl Kerns

submission deadline 20 Apr 2026 | 3 articles | Viewed by 7809 | Submission Open

Keywords: sperm development ; germ cell proliferation ; sperm cell metabolism ; seminal fluid biochemical composition ; spermatogenesis ; epididymal maturation ; sperm capacitation ; oocyte activation

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Nanofibrous Biomaterials for Biomedicine and Medical Applications

edited by Jong-Young Kwak

submission deadline 20 Apr 2026 | 3 articles | Viewed by 7213 | Submission Open

Keywords: nanofibers; biomaterials; 3D scaffold; 3D cell culture; tissue engineering; drug release

(This special issue belongs to the Section Materials Science)

Advanced Therapy Using Human Mesenchymal Stem Cells (MSCs) and MSC Extracellular Vesicles

edited by Tong Ming Liu and Xiaoman Luo

submission deadline 20 Apr 2026 | 3 articles | Viewed by 6965 | Submission Open

Keywords: mesenchymal stem cells; extracellular vesicles; MSCs; MSC-EVs; regenerative medicine

(This special issue belongs to the Section Molecular Biology)

Microbiome Modulation Through Probiotics: Molecular Insights and Therapeutic Applications

edited by

Satya Prakash

submission deadline 20 Apr 2026 | 2 articles | Viewed by 6726 | Submission Open

Keywords: live bacterial cells; prebiotic agents; synbiotic formulations; probiotic formulations; microbial dysbiosis; inflammation; oxidative stress; host– microbe interactions

(This special issue belongs to the Section Molecular Microbiology)

Molecular Insights into Antioxidant and Anti-Inflammatory Properties of Bioactive Compounds

edited by

Gang Ye

submission deadline 20 Apr 2026 | 2 articles | Viewed by 6724 | Submission Open

Keywords: antioxidant; anti-inflammatory; bioactive compounds; artificial intelligence; multiomics

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Advances in Epigenetics of Mental Disorders

edited by

Claudio Brasso

submission deadline 20 Apr 2026 | 1 articles | Viewed by 6681 | Submission Open

Keywords: mental disorders; epigenetic; epigenomic; gene– environment interactions

(This special issue belongs to the Section Molecular Neurobiology)

Mitochondrial Functions and Dynamics

edited by

Raffaella Isola

submission deadline 20 Apr 2026 | 1 articles | Viewed by 6569 | Submission Open

Keywords: bioenergetics; mitochondrial biogenesis; mitochondrial morphology; apoptosis; mitophagy; reactive oxygen species; calcium homeostasis; cardiovascular diseases; neurodegenerative diseases; in vitro; cellular; and animal models; myopathies; mitochondria and immune system

(This special issue belongs to the Section Molecular Biology)

Molecular Signalling in Multitrophic Systems Involving Arthropods

edited by

Francesca Barbero

submission deadline 20 Apr 2026 | 4 articles | Viewed by 6493 | Submission Open

Keywords: insects; plants; microorganisms; communication; symbioses; eavesdropping

(This special issue belongs to the Section Molecular Biology)

Newer Pharmacological Treatment Concepts for Patients with Acute Coronary Syndrome

edited by

Dimitrios Patoulias

submission deadline 20 Apr 2026 | 2 articles | Viewed by 6488 | Submission Open

Keywords: acute coronary syndrome (ACS); molecular studies; antiplatelet; anticoagulant drugs; lipid-lowering therapies

(This special issue belongs to the Section Molecular Pharmacology)

The Role of Glycans in Immune Regulation

edited by Senlian Hong

submission deadline 20 Apr 2026 | 2 articles | Viewed by 6295 | Submission Open

Keywords: glycoimmunology; glycotherapy; vaccines; glycan synthesis; immune tolerance

(This special issue belongs to the Section Molecular Immunology)

Recent Advances in Molecular Breeding for Drought and Salt Stress Tolerance in Crops: 2nd Edition

edited by

Zhaoshi Xu

submission deadline 20 Apr 2026 | 4 articles | Viewed by 6229 | Submission Open

Keywords: drought; salt; heat; cold; gene regulation; genomic research; multiomics; epigenetics; stress signal transduction

(This special issue belongs to the Section Molecular Plant Sciences)

Genetic and Epigenetic Analyses in Cancer

edited by Jing Gong

submission deadline 20 Apr 2026 | 5 articles | Viewed by 6225 | Submission Open

Keywords: epigenetics; genetic mutations; chromosomal instability; DNA methylation; histone modifications; non-coding rnas; multi-omics; transcriptomics; proteomics; drug resistance in cancer; cancer biomarkers; therapeutic targets in cancer

(This special issue belongs to the Section Molecular Genetics and Genomics)

Advances in Antibody–Drug Conjugates

edited by Bing Sun

submission deadline 20 Apr 2026 | 1 articles | Viewed by 6196 | Submission Open

Keywords: antibody– drug conjugate (ADC); cancer treatment; non-oncology indications; antibody selection; payload; linker; conjugation chemistry

(This special issue belongs to the Section Molecular Immunology)

Recent Research of Phytochemicals in Health and Disease

edited by Sachiko Koyama,

Thomas Heinbockel

and

Vonnie Shields

submission deadline 20 Apr 2026 | 2 articles | Viewed by 6166 | Submission Open

Keywords: phytochemicals with bioactive properties; health; brain function; regeneration; wound healing; treatment; and prevention of diseases; delivery routes and delivery methods; formulation of phytochemicals to overcome their hydrophobic nature and enhance their stability; drugs; supplements to drugs; and supplements for health maintenance; nourishment and phytochemicals; drug side effects; COVID-19

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Wheat Genetics and Genomics: 3rd Edition

edited by

Xiaojun Nie

submission deadline 20 Apr 2026 | 4 articles | Viewed by 6145 | Submission Open

Keywords: wheat; genetics; molecular breeding; genome variation; multiomics

(This special issue belongs to the Section Molecular Plant Sciences)

Protein Folding, Misfolding, and Related Diseases

edited by

Ludmilla Morozova-Roche

submission deadline 20 Apr 2026 | 3 articles | Viewed by 6098 | Submission Open

Keywords: protein folding; misfolding; amyloid; neurodegenerative diseases; chaperons; mechanisms; regulation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Displaying special issue 2651-2700 on page 54 of 69.

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