Molecular and Physiological Mechanisms of Exercise
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 20 September 2025 | Viewed by 5134
Special Issue Editor
Special Issue Information
Dear Colleagues,
Molecular biology has its place at the point of connection between biochemistry and genetics, seeking to determine the molecular mechanisms underlying vital cellular functions. More specifically, the study of molecular mechanisms, as directed toward the underlying mechanisms behind athletic performance, has seen advances made in the development and refinement of omics technologies. Multi-Omics, a combination of the fields of genomics, proteomics, transcriptomics, metabolomics, metagenomics, and epigenomics—together with recently improved analyses of big data, artificial intelligence, and bioinformatics—is opening the door to extraordinary possibilities for better understanding the cellular functions and molecular mechanisms of exercise in professional and amateur athletes of all ages.
This combination of omics data may aid efforts in identifying biochemical biomarkers and/or genes related to athletic performance, fatigue, nutrition, energetics, overtraining, stress, inflammation, cardiorespiratory function, sensitivity to injuries, and more. Subsequently, this can bring about predictions of gene expression and molecular characteristics of athletic performance, broaden the understanding of the mechanisms of biochemistry and the physiology of exercise, and potentially open avenues for understanding connections between numerous gene expressions and their effects on molecules involved in nutrition, metabolism and energetics, immune response, inflammation, stress, and hormonal control related to sport and exercise.
As a result, the emerging field of metagenomics raises the possibility of studying relationships that are not limited to already established connections between the gut and brain or the gut and muscles, moving beyond these fields instead.
We therefore invite authors to submit original research papers and review articles with a focus on application for practitioners in the field of athletic performance and health improvement. In particular, we encourage both scientists and practitioners to provide their contributions to this Special Issue.
Topics of interest for this Special Issue include, but are not limited to, the connections between gene expression and their effect on molecules involved in the following areas:
- Nutrition;
- Metabolism and energetics;
- Immune response;
- Inflammation;
- Stress;
- Hormonal control related to sport and exercise;
- Prevention and injury reduction in sports.
Dr. Zoran Nikolovski
Guest Editor
Manuscript Submission Information
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Keywords
- molecular biology
- biochemistry and exercise
- athletic performance
- multi-omic
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