Microbiome Modulation Through Probiotics: Molecular Insights and Therapeutic Applications
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Microbiology".
Deadline for manuscript submissions: 20 June 2025 | Viewed by 1504
Special Issue Editor
Interests: drug delivery; gene therapy; biomedicine; nanoparticles; nanomedicine; nanotechnology; the microbiome; probiotics; chronic diseases; Alzheimer’s; cancer; aging; targeted delivery
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Microbiome-engineered therapeutics hold considerable promise to target a variety of diseases through beneficial modulation of the gut microbiota composition and function. The use of probiotics to manipulate the microbiome and gastrointestinal (GI) environment is an attractive option to restore microbial homeostasis and host health. Although numerous probiotic formulations are still early in development or pre-clinical testing, some have proven clinically significant by promoting the abundance of beneficial microbes and metabolites, reducing inflammation, and improving systemic health while acting as a safe alternative to pharmacotherapies. Their suitability for therapeutic applications is attributed to strain-specific bioactivities, prolonged GI transit colonization, formulation preparation, probiotic form, and dosage, among several other factors.
This Special Issue will explore the latest progress in the use of probiotics to modulate the microbiome for therapeutic indications and the underlying mechanisms. You are invited to contribute to this Special Issue of the International Journal of Molecular Sciences, titled “Microbiome Modulation Through Probiotics: Molecular Insights and Therapeutic Applications.” This Special Issue will focus on the utility of microbiome-engineered therapies in the prevention, treatment, or management of disease, and their requirements for clinical translation.
Prof. Dr. Satya Prakash
Guest Editor
Manuscript Submission Information
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Keywords
- live bacterial cells
- prebiotic agents
- synbiotic formulations
- probiotic formulations
- microbial dysbiosis
- inflammation
- oxidative stress
- host–microbe interactions
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