Heart Failure: From Molecular Basis to Therapy 2.0

Dear Colleagues,

As is well known, globally, heart failure represents the non-transmittable epidemic of the third millennium in terms of prevalence, costs, and mortality. Despite prevention, efficient screening, and early-treatment programs, heart failure is still a great problem for both physicians and healthcare systems. The Special Issue “Heart Failure: From Molecular Basis to Therapy” aims to stimulate comprehensive research for a holistic approach. This Special Issue will accept articles on chronic and acute heart failure and on its etiologies, with a particular focus on the study of its molecular basis, of the diagnosis of its physiopathological pathways, including cardiac hypertrophy, fibrosis, inflammation, angiogenesis, and apoptosis, in animal models and in human, as well as on the study of new therapeutic targets, including new pharmacological and non-pharmacological strategies.

The purpose of this Special Issue is to collect original research articles and reviews that concern the heart failure and beyond, in order to have a more complete comprehension of the pathophysiology of heart failure, considering all the aspects of this complex puzzle.

This Special Issue follows on from a past and very successful collection on “Heart Failure: From Molecular Basis to Therapy” (https://www.mdpi.com/journal/ijms/special_issues/Heart_Failure_2019). Contributions from different fields of research at a molecular level are welcomed. Clinical research and survey studies are not suitable for this Special Issue of IJMS.

Prof. Dr. Francesco Fedele
Prof. Dr. Paul J. Mather
Guest Editors

Manuscript Submission Information

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