Role of G-Protein Coupled Receptors in Cardiovascular Diseases

Dear Colleagues,

Cardiovascular diseases (CVDs) are a group of disorders of the heart and blood vessels, including coronary heart disease, cerebrovascular disease and thrombosis. Although over the years, significant efforts have been made to prevent or treat these diseases, it still remains one of the leading causes of death worldwide. The inflammatory processes in CVDs are facilitated by a network of circulating immune cells and tissue resident cells, which is orchestrated by various mediators which interact, bind and induce signaling. Over the last years, G protein coupled receptors (GPCRs) emerged as important players in recognizing these mediators, both in steady state and inflammatory processes like CVDs. GPCRs are seven-transmembrane domain receptors and can be subdivided in several sub-classes and subgroups. In order to better comprehend the pathology behind CVDs, it is important to obtain a good overview of the role of GPCRs and the underlying molecular mechanisms. Therefore, the present Special Issue aims to provide an current state-of-the-art overview of the role of GPCRs in CVDs.

Dr. Emiel P.C. van der Vorst
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.