Aging and Risk Factors in Cardiovascular Disease: Cellular, Molecular and Epigenetic Insights

Dear Colleagues,

Aging is a major non-modifiable risk factor in the occurrence of cardiovascular disease (CVD). Moreover, additional risk factors associated with advancing age, including obesity, diabetes, and hypertension, are known to contribute to detrimental arterial and cardiac remodeling and complicate the CVD.

Increasing clinical and experimental studies have established a multitude of pathways and signals, including epigenetic pathways, influenced by aging and other risk factors that are responsible for key cardiovascular modifications involved in CVD, such as senescence and maladaptive differentiation of vascular and cardiac cells, inflammation, and a reduction in the number and functionality of stem cells.

This Special Issue aims to present a collection of innovative research papers and reviews addressing various aspects of the molecular and (epi)genetic mechanisms underpinning cardiovascular modifications occurring with aging and other risk factors responsible for CVD onset and progression.

Papers published in IJMS (International Journal of Molecular Sciences) are encouraged to include results at molecular level. So, we suggest we could focus it in our summary. General speaking, partial clinical researches and survey studies are not suitable for /IJMS/

Dr. Maria Cristina Vinci
Dr. Angela Raucci
Guest Editors

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