Molecular Mechanisms and Pathogenesis of Cardiac Diseases

Dear Colleagues,

Emerging evidence has suggested molecular regulating mechanisms play vital roles in pathophysiology of cardiac diseases. Epigenetic mechanisms including non-coding RNA, histone modification, and DNA methylation are crucial connectors to genetics and environmental factors to modify gene expression and protein functions in cardiac diseases. ER stress and inflammasome are implicated in inflammatory processes and also play critical roles in the onset and progression of cardiac diseases. Besides, the mitochondria are central regulators in cardiac metabolism, biosynthesis, redox balance, calcium homeostasis, and cell death. Therefore, the pathological molecular signalling pathways that lead to mitochondrial dysfunction are also much considered in cardiac diseases.

The Special Issue, entitled "Molecular Mechanisms and Pathogenesis of Cardiac Diseases", aims to provide a research platform for the collection of the latest original and review articles covering molecular biological studies of factors related to the control of cardiac diseases and action mechanisms of therapeutic drugs that are targeted at them.

Dr. Yu-Hsun Kao
Guest Editor

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