Surface-Functionalized Nanoparticles: Preparations, Characterizations, and Applications

Dear Colleagues,

With their unique physicochemical properties and nanoscale effects, nanoparticles can modulate the basic properties and bioactivity of drugs. These features make them attractive tools for diverse biomedical applications, especially in the field of drug delivery. Over the decades, nanocarriers have been extensively investigated for improved pharmacokinetics and biodistribution, increased stability, reduced toxicities, controlled release, and site-specific delivery of therapeutics. However, the efficacy of nanocarrier-based drug delivery systems is dependent mainly on their controlled interactions with biomolecules. Therefore, nanoparticles have often been surface-functionalized with various ligands, not only to impart site-specificity and increase cell penetration but also to provide stealth properties and improve payload capacity. For example, the surface functionalization of nanoparticles has made remarkable advances in tumor-targeted delivery and drug delivery across the blood-brain barrier. This Special Issue will focus on recent progress in nanotechnology in the areas of basic and applied research, as well as clinical medicine. Topics of interest include but are not limited to cutting-edge research on the preparation of surface-functionalized nanoparticles and their in vitro and in vivo evaluation. Further, the interaction between nanoparticles and bio-interfaces will also be included.

Prof. Dr. Jagdish Singh
Dr. Buddhadev Layek
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Prof. Dr. Jagdish Singh
Dr. Buddhadev Layek
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.