RNA Informatics
This special issue belongs to the section "Molecular Informatics".
Special Issue Information
Dear Colleagues,
Recent studies have shown that there are a large number of noncoding RNAs (ncRNAs) that are not translated into proteins but play important roles on various cellular functions. For example, several studies have suggested more long noncoding RNAs (lncRNAs) exist than messenger RNAs in higher eukaryote including human, and elucidating the functions of these lncRNAs is an urgent task in current molecular biology. On the other hand, various types of RNA-related omics data such as transcriptome (e.g., RNA-seq), epi-transcriptome (e.g., m6A-seq, m1A-seq), structurome (e.g., DMS-seq, SHAPE-seq), and interactome (e.g., CLIP-seq) are accumulating in the world. Integrating these omics data with bioinformatic approaches has also become important in RNA biology. In addition to natural RNAs, artificial RNAs such as RNA aptamers are also attracting attention from researchers as a new generation of target molecules for drug discovery; computational design of RNA sequence (e.g., RNA aptamer design, RNA inverse folding) is an important problem in this field. This Special Issue covers all aspects of RNA informatics. We highly welcome papers on both fundamental computational methods for analyzing RNAs and omics data analysis on RNAs.
Prof. Dr. Michiaki Hamada
Prof. Dr. Akito Taneda
Guest Editors
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Keywords
- ncRNA (e.g., miRNA, piRNA, snoRNA)
- lncRNA
- Omics data (e.g., RNA-seq, CLIP-seq, m6A-seq, ribo-seq)
- RNA aptamer
- RNA design (e.g., inverse folding)
- RNA interactome (RNA-protein interaction, RNA-RNA interaction)
- RNA modification (e.g., m6A, m1A, Inosine)
- RNA structure (e.g., secondary structure, tertiary structure, G4)
- RNA alignment
- RNA classification
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Published Papers
Int. J. Mol. Sci. - ISSN 1422-0067