Molecular Mechanisms of RNA Interactions and Biomarker Discovery for Human Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Informatics".
Deadline for manuscript submissions: 31 March 2026 | Viewed by 20
Special Issue Editor
Interests: bioinformatics; system biology; machine learning and complex networks
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The rapid development of high-throughput sequencing and molecular biology technologies has greatly advanced our understanding of the roles of RNAs in health and disease. RNA molecules, including mRNAs, microRNAs, lncRNAs, and circRNAs, participate in complex interaction networks that regulate gene expression and cellular functions. Dysregulation of these interactions has been closely associated with the initiation and progression of various human diseases, making them promising biomarkers and therapeutic targets.
Disease biomarker screening based on RNA profiles provides powerful strategies for early diagnosis, prognosis evaluation, and personalized medicine. Furthermore, understanding RNA–RNA and RNA–disease interactions enables us to uncover novel regulatory mechanisms underlying pathogenesis. In addition, drug–RNA interaction studies are opening new avenues for therapeutic intervention, including the development of RNA-targeting drugs and the repositioning of existing compounds.
This Special Issue will highlight recent advances in RNA-based biomarker discovery, RNA interaction networks, RNA–disease associations, and drug–RNA interaction mechanisms. We welcome submissions of original research articles and comprehensive reviews that present novel insights, computational methods, experimental validations, or translational applications in these areas.
Prof. Dr. Lei Wang
Guest Editor
Manuscript Submission Information
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Keywords
- biomarker discovery
- RNA interactions
- RNA–disease associations
- drug–RNA interactions
- therapeutic targets
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