The Anti-Inflammatory and Antioxidant Potential of Phytochemicals
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".
Deadline for manuscript submissions: 31 October 2025 | Viewed by 20
Special Issue Editor
Interests: phytochemicals; chemoprevention; antioxidant defences; anti-inflammation; hair growth; phase II enzymes; signal transduction
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Chronic inflammation is a key driver of various non-communicable diseases, including cardiovascular disease, diabetes, neurodegeneration, and cancer. Increasing research has demonstrated that phytochemicals and dietary bioactive compounds—such as polyphenols, carotenoids, terpenoids, and alkaloids—can modulate inflammatory responses through diverse molecular mechanisms. These naturally occurring compounds, derived from a broad spectrum of plant-based foods, herbs, and functional ingredients, have shown the capacity to influence immune regulation, oxidative stress, and key signaling pathways including NF-κB, MAPK, JAK/STAT, and Nrf2.
This Special Issue invites original research articles and reviews that explore the anti-inflammatory potential of dietary compounds, from molecular mechanisms to clinical efficacy. Topics of interest include novel compound discovery, structure–activity relationships, bioavailability, metabolic transformation, and synergistic interactions among dietary components. Studies employing in vitro models, animal systems, human clinical trials, or advanced in silico approaches are all welcome. Through this issue, we aim to expand the understanding of food-derived compounds as modulators of inflammation and promote their development as therapeutic or preventive agents in chronic disease management.
Prof. Dr. Woo-Sik Jeong
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- phytochemicals
- dietary bioactives
- inflammation
- natural compounds
- functional foods
- oxidative stress
- cytokine modulation
- NF-κB signaling
- chronic diseases
- plant-derived metabolites
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
