The Role of Bioactive Lipids in Health and Disease

Dear Colleagues,

International Journal of Molecular Sciences (ISSN 1422-0067, IF 6.208) is currently running a Special Issue focused on "The Role of Bioactive Lipids in Health and Disease". Based on your excellent expertise, we would be thrilled if you could submit a paper to this issue.

Bioactive lipids are lipids involved in signaling in every cell of every organism. Over the past two decades, they have become increasingly important in many areas of biology. They are the main diffusion mediators of the inflammatory response in tissues and regulate the polarity of cell membranes; As particularly prominent signaling molecules in the immune system, various bioactive lipids are required for the proper functioning of both the innate and adaptive immune system, in the vesicle traffic required to deliver many proteins to the appropriate organelles and to maintain structure and order within the cell. Currently, over thousands of bioactive lipids, including fatty acids and their metabolic products, acylglycerol derivatives, endocannabinoids, lysophospholipids, sphingolipids, cholesterol metabolites, etc., and sterols, sphingolipids have numerous functions important for homeostatic regulation and disease pathologies, such as metabolic diseases, cancer, heart disease, neurodegenerative disorders, obesity, and diabetes. The more recently identified superfamily of specialized pro-resolving lipid mediators (SPMs) takes a center stage in the process of resolution of inflammation by activating a series of cellular and molecular events that lead to spontaneous regression of inflammatory processes and restoration of tissue homeostasis.

In this Special Issue, original research and review articles focused on the field and, specifically, the molecular mechanism of the bioactive lipids participating in homeostasis and related disorders, identifying receptors, and exploring their signal transduction, are warmly welcome.

Dr. Valerio Chiurchiù
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.