Advances in Biomarker and Therapeutic Target Discovery in the Era of Omics Sciences

Dear Colleagues, 

Technological advances have led to the development of high-throughput omics approaches, which can measure thousands of biological molecules simultaneously, including nucleic acids, proteins and metabolites, in various biospecimens, such as cells, tissues and biofluids, based on the omics technology employed. The term omics encompasses multiple disciplines, such as genomics, transcriptomics, epigenomics, proteomics, metabolomics, lipidomics, nutrigenomics and microbiomics.

High-dimensional data generated by these applications from healthy and diseased samples can accelerate the rate of discovery, improve the understanding of complex diseases and support future perspectives of omics sciences, such as the discovery of diagnostic biomarkers and potential therapeutic targets.

Although the large amount of information obtained by omics applications represents a promising data source, its interpretation and insights remain an ongoing challenge for researchers. In addition, currently, specific analytical tools are designed for individual omics disciplines. However, data integration of multiomics strategies must be realized to establish a holistic understanding of molecular mechanisms involved in disease development and progression.

This Special Issue, “Advances in biomarker and therapeutic target discovery in the era of omics sciences”, welcomes original research and review articles focused on omics applications, which provide valuable insight into the identification of possible biomarkers and targets for the diagnosis and treatment of human diseases.

Dr. Monica Currò
Guest Editor

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