Influenza Pathogenesis and Vaccine Development
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Microbiology".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 9
Special Issue Editor
2. Avian and Rabbit Diseases Department, Faculty of Veterinary Medicine, University of Sadat City, Menofia Governorate 32897, Egypt
3. Prophy-Institute for Applied Prophylaxis, 59159 Bönen, Germany
Interests: natural products: extraction, biological activities; avian diseases: epidemiology and molecular epidemiology; development and evaluation of vaccines (molecular-based, inactivated, and live attenuated)
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Special Issue Information
Dear Colleagues,
Influenza viruses continue to challenge global health, animal welfare, and food security. Beyond seasonal outbreaks, emerging strains, including zoonotic and highly pathogenic avian influenza (HPAI) viruses, pose increasing threats due to interspecies transmission, viral evolution, and limited vaccine efficacy. Understanding the pathogenesis of influenza across species and developing more effective vaccines represent critical steps toward better prevention and control. For this Special Issue, we welcome high-quality original research articles, reviews, short communications, and perspectives that will advance our understanding of influenza virus pathogenesis and vaccine development. Topics of interest include, but are not limited to, the following:
- Molecular mechanisms behind influenza virus infection and host adaptation;
- Interspecies transmission, including avian-to-mammal spillover events;
- Viral immune evasion and host immune responses;
- Novel vaccine platforms and next-generation influenza vaccines;
- Cross-protective and universal vaccine strategies;
- Antigenic drift and shift—implications for vaccine design;
- Animal models for studying influenza infection and immunity;
- One Health perspectives and control.
We particularly welcome contributions exploring the dynamic interfaces of human, animal, and environmental health, as well as proposing innovative tools for pandemic preparedness. We will share new insights into influenza biology and work together to strengthen global defenses against future outbreaks.
Dr. Awad Shehata
Guest Editor
Manuscript Submission Information
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Keywords
- avian influenza
- influenza virus
- influenza surveillance
- interspecies transmission
- immune response
- pandemic preparedness
- pathogenesis
- One Health
- universal vaccines
- vaccine development
- viral adaptation
- viral evolution
- zoonotic infections
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