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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Pediatric Neurological Disorders: Diagnostic and Management Innovations

edited by Hui Xiong

submission deadline 30 Nov 2026 | Viewed by 167 | Submission Open

Keywords: pediatric neurological disorders; diagnostic and Management Innovations; biomarkers; neuroimaging techniques; genetic test; artificial intelligence-assisted; personalized treatment

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Breast Imaging: Improving Detection and Diagnosis

edited by

Graziella Di Grezia

submission deadline 30 Nov 2026 | Viewed by 162 | Submission Open

Keywords: breast cancer screening; digital breast tomosynthesis (DBT); contrast-enhanced mammography (CEM); breast MRI; artificial intelligence; radiomics; automated breast ultrasound (ABUS)

(This special issue belongs to the Section Medical Imaging and Theranostics)

Novel Advances in Allergy Diagnosis, 2nd Edition

edited by

Zenon Brzoza

submission deadline 30 Nov 2026 | Viewed by 157 | Submission Open

Keywords: allergic diseases; diagnostic tools and techniques; artificial intelligence; biomarkers; point-of-care testing and wearable devices

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Management in Otolaryngology, 2nd Edition

edited by

Rong-San Jiang

submission deadline 30 Nov 2026 | 1 articles | Viewed by 155 | Submission Open

Keywords: ear; diagnosis; head and neck; management; nose; otolaryngology; throat

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

New Generation Radiology: Towards a New Standard of Diagnostic Accuracy

edited by

Emanuele David

submission deadline 30 Nov 2026 | Viewed by 146 | Submission Open

Keywords: radiology; medical imaging; precision medicine; diagnosis; artificial intelligence

(This special issue belongs to the Section Medical Imaging and Theranostics)

Recent Advances in Obstetrics and Gynecology Diagnostics

edited by Florian Recker

submission deadline 30 Nov 2026 | Viewed by 146 | Submission Open

Keywords: obstetrics; gynecology; prenatal diagnosis; fetal medicine; ultrasound imaging; artificial intelligence; digital health; biomarkers; maternal-fetal medicine; diagnostic innovation

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Multimodal Diagnostics Using Medical Imaging and Liquid Biopsy: Clinical Translation and Implementation

edited by Yoshihisa Shimada

submission deadline 30 Nov 2026 | Viewed by 143 | Submission Open

Keywords: medical imaging; liquid biopsy; multimodal diagnostics; clinical translation; precision medicine; biomarkers; real-world clinical application

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Recent Advances in Echocardiography, 3rd Edition

edited by

Giulia Elena Mandoli

and Antonio Capolongo

submission deadline 30 Nov 2026 | Viewed by 136 | Submission Open

Keywords: standard echocardiography; speckle tracking echocardiography; strain; myocardial deformation; 3D echocardiography; valvular reconstruction; differential diagnosis; artificial intelligence

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in the Diagnosis and Phenotyping of Metabolic Disorders

edited by

Zhiguang Su

submission deadline 30 Nov 2026 | Viewed by 133 | Submission Open

Keywords: metabolic disorders; precision diagnosis; biomarker discovery; multi-omics; artificial intelligence (AI); disease phenotyping; diagnostic technologies; clinical decision support

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Thyroid Cancer Diagnosis and Management: Current Status, Challenges, and Future Directions

edited by

Merima Goran

and Nikola Jeftic

submission deadline 30 Nov 2026 | Viewed by 124 | Submission Open

Keywords: thyroid cancer; lymph node metastases; lymph node dissection; active surveillance; TI RADS classification; Bethesda categories; thyroidectomy; thyroglobulin; radioiodine therapy

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Oncology Imaging and Radiotherapy: From Diagnosis to Personalized Management

edited by Gokoulakrichenane Loganadane and

Mattia Falchetto Osti

submission deadline 30 Nov 2026 | Viewed by 121 | Submission Open

Keywords: oncology imaging; radiotherapy; MR-guided radiotherapy; MR-LINAC; radiomics; artificial intelligence; image-guided radiotherapy (IGRT); multiparametric MRI

(This special issue belongs to the Section Medical Imaging and Theranostics)

Recent Advances in the Diagnosis and Management of Head and Neck Cancers

edited by Jessica Lyn Geiger

submission deadline 30 Nov 2026 | Viewed by 118 | Submission Open

Keywords: head and neck squamous cell carcinoma (HNSCC); advanced thyroid carcinoma; diagnosis and detection; salivary gland malignancies; radiotherapy; neoadjuvant immunotherapy

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Precision Medicine in Valvular Heart Disease: Diagnosis and Management

edited by Roney Orismar Sampaio

submission deadline 30 Nov 2026 | Viewed by 93 | Submission Open

Keywords: precision medicine; valvular heart disease; biomarkers; aortic stenosis; mitral regurgitation; cardiovascular imaging

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Modern Diagnosis and Management in Abdominal Surgical Oncology

edited by Spiros G. Delis

submission deadline 30 Nov 2026 | Viewed by 88 | Submission Open

Keywords: gastrointestinal; hepatobiliary; and pancreatic cancers; abdominal surgical oncology; surgical techniques; diagnosis; medical imaging

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Diagnostic Approaches and Biomarkers of Polycystic Ovary Syndrome

edited by Enrico Carmina

submission deadline 30 Dec 2026 | Viewed by 129 | Submission Open

Keywords: polycystic ovary syndrome (PCOS); anti-mü llerian hormone (AMH); rotterdam criteria; metabolic phenotypes; adolescent PCOS diagnosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Novel Methods and Devices for Monitoring and Diagnosing in Critical Care

edited by

Zhongheng Zhang

submission deadline 31 Dec 2026 | 7 articles | Viewed by 17416 | Submission Open

Keywords: hemodynamic monitoring; perfusion; heart-lung interactions; novel biomarkers; machine learning; ultrasound; therapeutic drug monitoring; wearable sensors

(This special issue belongs to the Section Point-of-Care Diagnostics and Devices)

Lung Cancer: Screening, Diagnosis and Management: 2nd Edition

edited by

Fu-Zong Wu

submission deadline 31 Dec 2026 | 5 articles | Viewed by 15123 | Submission Open

Keywords: lung cancer; LDCT; overdiagnosis; artificial intelligence; deep learning; prognosis; radiomics; texture analysis; thoracic surgery

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Insights into Perinatal Medicine and Fetal Medicine—2nd Edition

edited by Paola Quaresima and Ilaria Fantasia

submission deadline 31 Dec 2026 | 6 articles | Viewed by 11468 | Submission Open

Keywords: fetal malformations; hypertensive disorders of pregnancy; gestational diabetes; fetal growth; in utero surgery; first-trimester screening; fetal aneuploidies

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnostic Methods in Forensic Pathology, Third Edition

edited by

Gennaro Baldino

and

Elvira Ventura Spagnolo

submission deadline 31 Dec 2026 | 7 articles | Viewed by 11434 | Submission Open

Keywords: multidisciplinary approach; forensic pathology; sudden/unexpected death; sepsis and health infections; suicide; gender violence; post-mortem immunohistochemistry; post-mortem CT; virtopsy

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Pathology and Diagnosis of Head and Neck Diseases

edited by

Eliano Cascardi

submission deadline 31 Dec 2026 | 6 articles | Viewed by 11306 | Submission Open

Keywords: head and neck disease; histopathology; oral tumors; cancer; biomarkers; digital pathology; AI applications; personalized medicine

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Progress in Chronic Pain: Bridging Basic and Clinical Research

edited by

Helder Cardoso-Cruz

and

Clara Monteiro

submission deadline 31 Dec 2026 | 2 articles | Viewed by 7956 | Submission Open

Keywords: chronic pain; pain prevention; new biomarkers in chronic pain; personalized treatment approaches; sensory and cognitive dimensions; neuropathic pain; inflammatory pain

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Clinical Diagnosis and Management in Pediatric Surgery

edited by Ioannis A. Valioulis

submission deadline 31 Dec 2026 | 5 articles | Viewed by 7003 | Submission Open

Keywords: pediatric surgery; neonatal surgery; pediatric urology; pediatric oncology; laparoscopy in children; robotic surgery for children; organ transplantation; diagnostic biomarkers

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Recent Advances in Pathology 2026

edited by

Francesca Sanguedolce

and

Roberta Mazzucchelli

submission deadline 31 Dec 2026 | 3 articles | Viewed by 6817 | Submission Open

Keywords: pathology innovations; molecular diagnostics; biomarkers and precision medicine; digital pathology; artificial intelligence in pathology; translational pathology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Molecular Techniques in Infectious Disease Diagnosis: Advances and Applications

edited by

Peisong Chen

submission deadline 31 Dec 2026 | 5 articles | Viewed by 4940 | Submission Open

Keywords: molecular diagnostics; PCR; NGS; CRISPR; antimicrobial resistance; point-of-care testing; metagenomics; pathogen detection

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Advances in Diagnosis and Management of Skin Diseases

edited by

Montserrat Fernández-Guarino

submission deadline 31 Dec 2026 | 5 articles | Viewed by 4689 | Submission Open

Keywords: dermatology; skin disease; molecular diagnostics; laboratory test; assessment of therapies

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Non-Invasive Diagnostic Technologies for Heart Diseases

edited by Dentamaro Ilaria

submission deadline 31 Dec 2026 | 4 articles | Viewed by 4598 | Submission Open

Keywords: transthoracic echocardiography; cardiac magnetic resonance; multimodality cardiovascular imaging; cardiac CT; transesophageal echocardiography; cardiovascular disease

(This special issue belongs to the Section Medical Imaging and Theranostics)

Cardiovascular Diseases: Advances in Diagnosis and Management

edited by

Thien Tan Tri Tai Truyen

submission deadline 31 Dec 2026 | 3 articles | Viewed by 4536 | Submission Open

Keywords: cardiovascular diseases; predictive risk score; mortality; prognosis; artificial intelligence; machine learning; large language models

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Recent Advances in AI and Hyperspectral Techniques for Medical Imaging

edited by

Hsianmin Chen

submission deadline 31 Dec 2026 | 2 articles | Viewed by 4448 | Submission Open

Keywords: AI in medical imaging; hyperspectral medical imaging; biomedical image processing; deep learning; image segmentation and classification; multimodal imaging; intelligent diagnostic systems; tissue characterization; spectral imaging in medicine; clinical applications of AI and HSI

(This special issue belongs to the Section Medical Imaging and Theranostics)

Artificial Intelligence in Cardiovascular and Stroke Imaging

edited by

Jasjit S. Suri

submission deadline 31 Dec 2026 | 3 articles | Viewed by 4003 | Submission Open

Keywords: artificial intelligence; cardiovascular; stroke imaging; diagnosis; prognosis

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Pathological Speech Classification and Processing for Advanced Medical Diagnosis

edited by

Juan Rafael Orozco-Arroyave

submission deadline 31 Dec 2026 | 2 articles | Viewed by 3809 | Submission Open

Keywords: pathological speech; medical diagnosis; classification and processing; Parkinson's disease; hypokinetic dysarthria; dysarthria; aphasia; voice disorders; dysphonia; AI

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Recent Advances in the Diagnosis and Management of Respiratory Disease: From Biomarkers to Treatment Decisions

edited by

Konstantinos Kostikas

and

Athena Gogali

submission deadline 31 Dec 2026 | 3 articles | Viewed by 3790 | Submission Open

Keywords: respiratory biologics; bronchoscopy; airways disease; exhaled biomarkers; artificial intelligence

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Current Diagnosis and Management of Metabolic Bone Diseases

edited by Liming Xiong

submission deadline 31 Dec 2026 | 3 articles | Viewed by 3528 | Submission Open

Keywords: metabolic bone disease; bone turnover markers; maintenance of bone homeostasis; multiorgan– bone axis; fracture risk assessment; diabetic osteopathy; precision management

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Multimodal Cardiac Imaging: Diagnostic and Prognostic Advances

edited by

Lucia La Mura

and Ciro Santoro

submission deadline 31 Dec 2026 | 2 articles | Viewed by 2985 | Submission Open

Keywords: cardiovascular imaging; cardiac CT; cardiac magnetic resonance; cardiac MRI; echocardiography; multimodality cardiovascular imaging; advanced echocardiography

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis and Prognosis of Pulmonary Diseases

edited by

Fabio Perrotta

and

Filippo Scialò

submission deadline 31 Dec 2026 | 1 articles | Viewed by 2382 | Submission Open

Keywords: interstitial lung disease; pulmonology; airway obstruction; pulmonary medicine; respiration disorders

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Artificial Intelligence in Diagnostic Imaging

edited by Arthur Rodriguez Gonzalez Cortes

submission deadline 31 Dec 2026 | 1 articles | Viewed by 2290 | Submission Open

Keywords: artificial intelligence; deep learning; large language models; convolutional neural networks; radiology

(This special issue belongs to the Section Medical Imaging and Theranostics)

Artificial Intelligence for Health and Medicine—2nd Edition

edited by

Daniele Giansanti

submission deadline 31 Dec 2026 | 2 articles | Viewed by 2073 | Submission Open

Keywords: artificial intelligence; deep learning; healthcare; image segmentation; disease prediction; monitoring

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Hematologic Tumors of the Bone: From Diagnosis to Prognosis

edited by Fabio Stagno

submission deadline 31 Dec 2026 | 1 articles | Viewed by 2064 | Submission Open

Keywords: bone marrow tumors; hematologic malignancies; diagnostic biomarkers; prognostic tools; targeted therapies

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnostics in Maxillofacial Oncology and Trauma

edited by

Ioanna Kalaitsidou

and

Benoît Schaller

submission deadline 31 Dec 2026 | 1 articles | Viewed by 2053 | Submission Open

Keywords: maxillofacial diagnostics; craniofacial trauma; oral and maxillofacial oncology; artificial intelligence in imaging; photon-counting CT (PCCT); molecular biomarkers; histopathology; radiomics; multimodal imaging; preoperative planning

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Imaging for Kidney Disease: Innovations in Diagnosis and Monitoring

edited by Abhilash Koratala

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1828 | Submission Open

Keywords: renal imaging; ultrasound innovations; precision diagnostics

(This special issue belongs to the Section Medical Imaging and Theranostics)

Biochemical Testing Applications in Clinical Diagnosis—2nd Edition

edited by

Donatella Coradduzza

submission deadline 31 Dec 2026 | 3 articles | Viewed by 1644 | Submission Open

Keywords: biochemical testing; clinical diagnosis; biomarkers; point-of-care tests; innovative analytical techniques

(This special issue belongs to the Section Clinical Laboratory Medicine)

Chronic Kidney Diseases: Diagnosis, Management, and Prognosis

edited by

Xujie Zhou

submission deadline 31 Dec 2026 | Viewed by 1409 | Submission Open

Keywords: chronic kidney diseases; IgA nephropathy; biomarkers; molecular mechanisms; therapeutic innovation; personalized medicine; translational research

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

(Bio)sensors for Medical Diagnostics

edited by

Mihaela Badea

Akhtar Hayat

and Sehrish Bilal

submission deadline 31 Dec 2026 | Viewed by 1384 | Submission Open

Keywords: sensors and biosensors; medical diagnostics; biomarker detection; point-of-care testing; lab-on-a-chip; wearable health technology; nanotechnology; signal transduction; early disease detection; clinical monitoring

(This special issue belongs to the Section Point-of-Care Diagnostics and Devices)

Advances in Sarcoma Diagnostics: Histopathology, Imaging, and Artificial Intelligence for Precision Management

edited by

Siu Wai Choi

submission deadline 31 Dec 2026 | Viewed by 1249 | Submission Open

Keywords: sarcoma diagnosis and prognosis; machine learning models; genomics in diagnosis; classification and prognosis; novel methods of treatment

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

AI-Powered Ophthalmic Diagnostics: From Image Segmentation to Disease Classification

edited by

Yanwu Xu

Weihua Yang

and

Huihui Fang

submission deadline 31 Dec 2026 | 2 articles | Viewed by 1156 | Submission Open

Keywords: ophthalmic artificial intelligence; medical image segmentation; disease classification; ocular imaging; deep learning and foundation models; explainable AI (XAI); clinical translation in ophthalmology

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in the Diagnostics and Management of Diseases of the Anterior Segment of the Eye

edited by

Sang Beom Han

submission deadline 31 Dec 2026 | 3 articles | Viewed by 1116 | Submission Open

Keywords: anterior segment disorder; cornea; cataract; anterior segment imaging; refractive surgery

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advanced Ultrasound Techniques in Diagnosis, Second Edition

edited by

Laith Riyadh Sultan

submission deadline 31 Dec 2026 | Viewed by 1097 | Submission Open

Keywords: super-resolution imaging; microvascular imaging (MVI); contrast-enhanced ultrasound; AI-guided ultrasound; quantitative analysis; diagnostic imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Molecular Diagnostics in Cardiovascular Diseases: From Biomarkers to Individualized Medicine

edited by

Priyanka Gokulnath

and

Michail Spanos

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1072 | Submission Open

Keywords: molecular diagnostics; cardiovascular diseases; biomarkers; individualized medicine; precision cardiology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Inflammatory Pathways and Diagnostic Strategies in Chronic Diseases

edited by

Liliana-Georgeta Foia

Maria Alexandra Mârțu

and

Minerva Codruta Badescu

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1068 | Submission Open

Keywords: chronic diseases; early diagnosis; non-invasive diagnosis; artificial intelligence application

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Update on Diagnosis in Cardiovascular Interventions

edited by

Alfredo E. Rodriguez

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1031 | Submission Open

Keywords: myocardial infarction; stents; coronary artery disease; drugs; coronary imaging; structural heart disease; meta-analysis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Diagnostic Imaging and Interpretation in Pediatric Radiology

edited by

André Lollert

submission deadline 31 Dec 2026 | 2 articles | Viewed by 986 | Submission Open

Keywords: pediatric radiology; pediatric MRI; pediatric CT; photon-counting CT; pediatric ultrasound; clinico-radiologic diagnostics; rare diseases; quantitative imaging; artificial intelligence; nuclear medicine

(This special issue belongs to the Section Medical Imaging and Theranostics)

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