Clinical Diagnosis and Management of Metabolic Bone Diseases
A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Clinical Diagnosis and Prognosis".
Deadline for manuscript submissions: 31 October 2026 | Viewed by 2174
Special Issue Editor
Interests: metabolic bone diseases; osteoporosis; menopause; aging; DXA; HR-pQCT
Special Issue Information
Dear Colleagues,
Osteometabolic diseases encompass a large number of disorders that affect bone homeostasis. In fact, the skeleton is a dynamic organ influenced by overall health. Its constant renewal is based on the sequence of resorption and neoformation, carried out by osteoclasts, osteoblasts, and osteocytes, with differences between the trabecular and cortical compartments. In adulthood, this remodeling becomes unbalanced during menopause and aging, but the participation of disorders of the calcium–phosphorus–vitamin D–PTH axis and other hormones, as well as systemic diseases, must be considered. In particular, obesity and diabetes, intestinal malabsorption, disturbances affecting bone marrow, glomerular and tubular function, among others, contribute to bone loss and fragility fractures. In this setting, imaging exams, such as X-rays, DXA, and HR-pQCT, and laboratory tests focused on possible comorbidities are fundamental for therapeutic decisions. The topics of this special issue aim to raise questions and suggest approaches to prevalent bone metabolic diseases in adults.
Prof. Dr. Maria Lucia Fleiuss Farias
Guest Editor
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Keywords
- bone
- PTH
- hyperparathyroidism
- chronic kidney disease-metabolic bone disorder
- osteoporosis
- DXA
- HR-pQCT
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