Diagnostics in Maxillofacial Oncology and Trauma

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Medical Imaging and Theranostics".

Deadline for manuscript submissions: 31 December 2026 | Viewed by 2034

Special Issue Editors


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Guest Editor
Department of Cranio-Maxillofacial Surgery, Inselspital, Bern University Hospital, University of Bern, CH-3010 Bern, Switzerland
Interests: maxillofacial oncology; salivary gland pathology; head and neck reconstruction; traumatology; skull base fractures; multidisciplinary surgery

E-Mail Website
Guest Editor
Department of Cranio-Maxillofacial Surgery, Inselspital, Bern University Hospital, University of Bern, CH-3010 Bern, Switzerland
Interests: maxillofacial surgery

Special Issue Information

Dear Colleagues,

This Special Issue aims to explore cutting-edge diagnostic tools and strategies in maxillofacial oncology and trauma. Rapid and accurate diagnosis is vital for the effective management of both neoplastic and traumatic conditions affecting the complex craniofacial region. In oncologic cases, the timely identification of tumor extent, bone invasion, and lymph node involvement is critical for surgical planning and prognosis, while in trauma cases, the precise mapping of fractures and soft tissue injuries is essential for restoring function and aesthetics.

This Special Issue aims to focus on emerging imaging modalities such as cone beam computed tomography (CBCT), magnetic resonance imaging (MRI), PET/CT, and the application of photon-counting CT (PCCT) in particular, which offers superior resolution and tissue characterization. We also aim to include advances in molecular diagnostics, histopathological assessment, and artificial intelligence (AI)-assisted technologies that support automated interpretation, radiomics, and integrated decision-making.

Furthermore, this Special Issue seeks to address the ongoing challenges in early detection, differential diagnosis, and individualized preoperative planning, especially in complex tumor cases or polytrauma. Contributions highlighting interdisciplinary collaboration between radiologists, maxillofacial surgeons, pathologists, and data scientists are strongly encouraged. Original research articles, comprehensive reviews, and well-documented clinical case series are welcome to be submitted, particularly those that aim to improve diagnostic accuracy, treatment outcomes, and the overall quality of patient care in the field of maxillofacial medicine.

Dr. Ioanna Kalaitsidou
Prof. Dr. Benoît Schaller
Guest Editors

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Keywords

  • maxillofacial diagnostics
  • craniofacial trauma
  • oral and maxillofacial oncology
  • artificial intelligence in imaging
  • photon-counting CT (PCCT)
  • molecular biomarkers
  • histopathology
  • radiomics
  • multimodal imaging
  • preoperative planning

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Published Papers (1 paper)

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20 pages, 508 KB  
Systematic Review
Management Strategies for Isolated Orbital Floor Fractures: A Systematic Review of Clinical Outcomes and Surgical Approaches
by Bayad Miran, Daniel J. Toneatti, Benoît Schaller and Ioanna Kalaitsidou
Diagnostics 2025, 15(23), 3024; https://doi.org/10.3390/diagnostics15233024 - 27 Nov 2025
Cited by 2 | Viewed by 1675
Abstract
Background/Objectives: Isolated orbital floor fractures are a common consequence of midfacial trauma and are frequently associated with functional and aesthetic complications such as diplopia, enophthalmos, infraorbital hypoesthesia, restricted ocular motility, and, in rare cases, blindness. Current therapeutic approaches vary significantly between different surgeons. [...] Read more.
Background/Objectives: Isolated orbital floor fractures are a common consequence of midfacial trauma and are frequently associated with functional and aesthetic complications such as diplopia, enophthalmos, infraorbital hypoesthesia, restricted ocular motility, and, in rare cases, blindness. Current therapeutic approaches vary significantly between different surgeons. This systematic review aimed to evaluate different treatment strategies for isolated orbital floor fractures to determine the most effective approaches. Methods: Electronic systematic searches were conducted using keywords to identify studies reporting isolated orbital floor fractures. Publications were screened for eligibility, and relevant data were extracted and evaluated. Results: This systematic review included 444 patients from 27 selected studies. 42 patients were treated conservatively, while 381 underwent various surgical interventions. Overall, the mentioned treatment modalities were successful in correcting enophthalmos (85.2%), diplopia (74.8%), ocular motility restriction (61.6%), and sensory disturbances (61.1%) in their respective patient cohorts. The complication and reoperation rates for the surgical interventions were low during the follow-up periods ranging from 6 weeks to 10 years. The timing, surgical approach, and reconstructive technique varied widely across the studies. Conclusions: Both conservative and surgical management of isolated orbital floor fractures can achieve satisfactory clinical outcomes. Clinical symptoms, defect size, and the surgeon’s preference define the ideal treatment modality. Full article
(This article belongs to the Special Issue Diagnostics in Maxillofacial Oncology and Trauma)
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