Current Diagnosis and Management of Metabolic Bone Disease
A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".
Deadline for manuscript submissions: 31 May 2026 | Viewed by 34
Special Issue Editor
Special Issue Information
Dear Colleagues,
Metabolic bone diseases (MBDs), including osteoporosis, diabetic osteopathy, and hepatic osteodystrophy, pose a mounting global burden exacerbated by aging and metabolic disorders. This Special Issue addresses critical gaps in the early detection and personalized management of MBDs, frequently undiagnosed until fracture. We invite cutting-edge research on the following areas:
- How novel biomarkers (bone turnover markers, metabolites, and endocrine/immune factors) enhance diagnostic precision and fracture risk prediction;
- Imaging innovations, including photon-counting DXA and AI-enhanced bone microarchitecture analysis, which surpass BMD limitations for fracture risk stratification;
- Pharmacotherapy innovations, including GLP-1 receptor agonists, improving BMD/fracture risk in diabetes and the skeletal safety of anti-diabetic drugs;
- Multiorgan–bone axis mechanisms wherein bone acts as an endocrine/metabolic hub, dynamically interacting with the liver, brain, kidneys, and so on via osteokines to fine-tune systemic homeostasis.
This Special Issue bridges translational research and clinical practice to advance risk stratification, treatment monitoring, and precision interventions. Submissions on genomic/proteomic studies, AI-driven diagnostics, and multidisciplinary approaches are encouraged.
Prof. Dr. Liming Xiong
Guest Editor
Manuscript Submission Information
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Keywords
- metabolic bone disease
- bone turnover markers
- maintenance of bone homeostasis
- multiorgan–bone axis
- fracture risk assessment
- diabetic osteopathy
- precision management
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