Special Issues

Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Artificial Intelligence in Healthcare submission deadline 31 Dec 2025 | 7 articles | Viewed by 13500 | Submission Open
Keywords: artificial intelligence; AI-driven radiomics; healthcare; digital radiology; precision medicine
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Artificial Intelligence in Pathological Image Analysis—2nd Edition
edited by
submission deadline 31 Dec 2025 | 6 articles | Viewed by 12219 | Submission Open
Keywords: histopathology; cytopathology; molecular pathology; surgical pathology; digital pathology; microscopy; whole slide image (WSI); clinical data; computer vision; deep learning; machine learning; computation; mathematics; domain adaptation; segmentation; classification; pattern recognition; explainable AI; reconstruction
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Clinical Presentation, Management and Prognosis of Infective Endocarditis
edited by , Alexander Weymann and Thanos Athanasiou
submission deadline 31 Dec 2025 | 2 articles | Viewed by 10040 | Submission Open
Keywords: infective endocarditis; clinical presentation; diagnostic modalities; antibiotic stewardship; surgical interventions; prognostic indicators
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Optical Imaging: Trends, Impact, and Application in Medical and Biomedical Diagnostics submission deadline 31 Dec 2025 | 6 articles | Viewed by 8547 | Submission Open
Keywords: vascular and tumor imaging; drug testing; blood flow characterization; tissue characterization and cell migration analysis; fluorescence microscopy (FM); optical coherence tomography (OCT); ultrasound imaging (sonography); multiphoton microscopy (MPM); photoacoustic tomography (PAT); computed tomography (CT); conebeam computed tomography (CBCT); magnetic resonance imaging (MRI); endoscopy; scanning laser ophthalmoscopy; super-resolution microscopy; hyperspectral imaging; diffuse optical tomography; spectroscopy; structured illumination microscopy (SIM); laser doppler imaging; artificial intelligence; machine learning; algorithm development
(This special issue belongs to the Section Biomedical Optics)
Inflammatory Pathologies
edited by Uday Nagesh Shivaji
submission deadline 31 Dec 2025 | 6 articles | Viewed by 7943 | Submission Open
Keywords: systemic chronic inflammation; biomarkers of inflammation; imaging in inflammatory pathology
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Artificial Intelligence Advances for Medical Computer-Aided Diagnosis—2nd Edition submission deadline 31 Dec 2025 | 6 articles | Viewed by 7286 | Submission Open
Keywords: image classification; image segmentation; medical image processing; biomedical optical imaging; medical signal processing; artificial intelligence; deep learning; machine learning; computer-aided diagnosis; explainable artificial intelligence
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Artificial Intelligence for Clinical Diagnostic Decision Making submission deadline 31 Dec 2025 | 4 articles | Viewed by 5680 | Submission Open
Keywords: artificial intelligence; machine learning; clinical decision support systems; health disparity; medical imaging; disease diagnosis; medical errors; patient safety
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Advances in Computed Tomography Imaging for Clinical Diagnosis—2nd Edition
edited by Ibrahim Yel
submission deadline 31 Dec 2025 | 5 articles | Viewed by 5655 | Submission Open
Keywords: computed tomography imaging; clinical diagnosis; dual-energy CT; photon-counting CT; image analysis
(This special issue belongs to the Section Medical Imaging and Theranostics)
Recent Advances and Challenges in Gastrointestinal Endoscopy
edited by
submission deadline 31 Dec 2025 | 5 articles | Viewed by 5127 | Submission Open
Keywords: diagnosis at an early stage; endoscopy; precancerous lesion
(This special issue belongs to the Section Biomedical Optics)
Current Issues on Kidney Diseases Diagnosis and Management 2025
edited by
submission deadline 31 Dec 2025 | 6 articles | Viewed by 4627 | Submission Open
Keywords: kidney diseases; renal involvement; AKI; CKD; glomerulopathies; diagnosis; treatment; dialysis; epidemiology; nephritic syndrome; nephrotic syndrome; biomarkers; urinalysis; oliguria; poliuria; electrolytes; acid-base balance
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Novel Methods and Devices for Monitoring and Diagnosing in Critical Care
edited by
submission deadline 31 Dec 2025 | 5 articles | Viewed by 3907 | Submission Open
Keywords: hemodynamic monitoring; perfusion; heart-lung interactions; novel biomarkers; machine learning; ultrasound; therapeutic drug monitoring; wearable sensors
(This special issue belongs to the Section Point-of-Care Diagnostics and Devices)
Advances in the Diagnosis and Management of Breast Cancer submission deadline 31 Dec 2025 | 3 articles | Viewed by 3553 | Submission Open
Keywords: prognostic and predictive factors; breast carcinoma; phylloid tumor; immunohistochemistry; diagnosis; breast cancer
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Advancements in Diagnostic Tools in the Emergency Department (ED): A Possible Help to Avoid Overcrowding
edited by Jacopo M. Legramante
submission deadline 31 Dec 2025 | 2 articles | Viewed by 2349 | Submission Open
Keywords: critical care; emergency medicine; diagnostics
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Eosinophilic Gastrointestinal Disorders: Advances in Diagnosis and Management submission deadline 31 Dec 2025 | 1 articles | Viewed by 2321 | Submission Open
Keywords: eosinophilic esophagitis; diagnosis; treatment; histology; epidemiology; risk factors; endoscopy; high resolution manometry; dietary therapy
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Liquid Biopsy: Cancer Diagnostic Biomarkers of the Future
edited by
submission deadline 31 Dec 2025 | 2 articles | Viewed by 2191 | Submission Open
Keywords: liquid biopsy; circulating tumor cells (CTCs); ctDNA testing; exosomes; blood analytes
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Images in the Diagnosis and Treatment of Macular Edema
edited by
submission deadline 31 Dec 2025 | 2 articles | Viewed by 2084 | Submission Open
Keywords: macular edema; diagnostic imaging; optical coherence tomography (OCT); fluorescein angiography; retinal imaging techniques
(This special issue belongs to the Section Medical Imaging and Theranostics)
Diagnostic and Prognostic Markers in Liver Diseases
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 2046 | Submission Open
Keywords: diagnostic and prognostic markers; non-invasive biomarkers; hepatology; liver disease; therapeutic response; disease progression; fibrosis; mortality; decompensation; infection
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Diagnostics and Therapeutic Explorations in Aging submission deadline 31 Dec 2025 | 1 articles | Viewed by 1379 | Submission Open
Keywords: molecular markers; genetics; epigenetics; biochemistry; biomarkers; telomeres; age-related disease; senescence; mitochondrial dysfunction; immunogenetics
(This special issue belongs to the Section Point-of-Care Diagnostics and Devices)
Advances in Echocardiography
edited by Grazia Canciello
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1301 | Submission Open
Keywords: echocardiography; cardiovascular imaging; three-dimensional echocardiography; strain imaging; TrueVue imaging; cardiac function assessment; clinical applications; non-invasive cardiology; artificial intelligence
(This special issue belongs to the Section Medical Imaging and Theranostics)
Pathology and Diagnosis of Head and Neck Diseases
edited by
submission deadline 31 Dec 2025 | 2 articles | Viewed by 1132 | Submission Open
Keywords: head and neck disease; histopathology; oral tumors; cancer; biomarkers; digital pathology; AI applications; personalized medicine
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Cardiovascular Diseases: Advances in Diagnosis and Management submission deadline 31 Dec 2025 | Viewed by 1116 | Submission Open
Keywords: cardiovascular diseases; predictive risk score; mortality; prognosis; artificial intelligence; machine learning; large language models
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Imaging in Oral Surgery: Advancing the Frontiers of Precision Diagnosis and Treatment Planning
edited by Anusha Vaddi
submission deadline 31 Dec 2025 | 1 articles | Viewed by 814 | Submission Open
Keywords: oral surgery; digital radiography; treatment planning; diagnosis; augmented reality; 3D printing
(This special issue belongs to the Section Medical Imaging and Theranostics)
The Clinical Diagnosis, Prognosis, and Management of Gastrointestinal Disease submission deadline 31 Dec 2025 | 1 articles | Viewed by 750 | Submission Open
Keywords: gastrointestinal diseases; colon cancer; appendicitis; clinical outcomes; prognosis
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Advances in the Diagnosis of Infectious Diseases and Microorganisms: 2nd Edition
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 632 | Submission Open
Keywords: clinical microbiology; antimicrobial resistance; diagnostic microbiology; molecular microbiology; HIV; infectious diseases
(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)
AI in Radiology and Nuclear Medicine: Challenges and Opportunities
edited by Ioannis M. Tsougos
submission deadline 31 Dec 2025 | 1 articles | Viewed by 521 | Submission Open
Keywords: diagnosis; prognosis; radiology; nuclear medicine; artificial intelligence (AI)
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Pathological Speech Classification and Processing for Advanced Medical Diagnosis submission deadline 31 Dec 2025 | Viewed by 484 | Submission Open
Keywords: pathological speech; medical diagnosis; classification and processing; Parkinson's disease; hypokinetic dysarthria; dysarthria; aphasia; voice disorders; dysphonia; AI
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Fetal Doppler Assessment: From Basic Research to Clinical Practice
edited by Luís Guedes-Martins
submission deadline 31 Dec 2025 | Viewed by 252 | Submission Open
Keywords: fetal Doppler; fetal growth restriction; preeclampsia; fetal-placental hemodynamics; fetal death; placental abruption; placental circulation; fetal cerebral circulation; fetal hepatic circulation; fetal heart function
(This special issue belongs to the Section Medical Imaging and Theranostics)
Metabolic Dysfunction Associated Steatotic Liver Disease: Diagnosis and Management
edited by
submission deadline 31 Dec 2025 | Viewed by 217 | Submission Open
Keywords: metabolic dysfunction; steatotic liver disease; diagnosis strategies; metabolic dysfunction-associated steatotic liver disease (MASLD); hepatic fibrosis and cirrhosis prevention
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Lung Cancer: Screening, Diagnosis and Management: 2nd Edition
edited by
submission deadline 31 Dec 2025 | Viewed by 138 | Submission Open
Keywords: lung cancer; LDCT; overdiagnosis; artificial intelligence; deep learning; prognosis; radiomics; texture analysis; thoracic surgery
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Novel Diagnostic Approaches and Treatment of Angina and Myocardial Ischemia submission deadline 31 Dec 2025 | Viewed by 132 | Submission Open
Keywords: ischemia; angina; chronic coronary syndromes; ANOCA; INOCA; CMD; CFR; microcirculation; scintigraphy; CMR
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Advances in Dental Diagnostics
edited by and Margherita Fontana
submission deadline 31 Dec 2025 | Viewed by 124 | Submission Open
Keywords: diagnosis; diagnostic imaging; artificial intelligence; caries; periodontitis; stomatognathic diseases
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Recent Advances in Epidemiological Diagnostics: Detecting and Controlling Infectious Diseases
edited by and W. Sumner Davis
submission deadline 31 Dec 2025 | Viewed by 100 | Submission Open
Keywords: epidemiological diagnostics; disease control; clinical practice and patient care; public health; infectious diseases
(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)
Neurodiagnostics in Public Health: Cognitive Decline, Mental Health, and Emerging Technologies submission deadline 31 Dec 2025 | Viewed by 99 | Submission Open
Keywords: neurocognitive disorders; dementia; mild cognitive impairment (MCI); neuropsychiatric diseases; biomarkers; imaging; artificial intelligence; digital diagnosis
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Advances in Diagnosis and Treatment in Pediatric Dentistry
edited by , and Federica Guglielmi
submission deadline 31 Dec 2025 | Viewed by 92 | Submission Open
Keywords: OSA; special needs patients; interceptive orthodontics; proteomics; 3D imaging; parafunctional habits
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Diagnostic Techniques in Obstetrics and Gynecology: Current Practices and Future Directions
edited by Giuseppina Porcaro
submission deadline 31 Dec 2025 | Viewed by 90 | Submission Open
Keywords: diagnosis; prognosis; obstetrics and gynecology markers; clinical practice and patient care
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Advances in Maternal and Fetal Medicine Research: from Diagnostics to Prognosis submission deadline 31 Dec 2025 | Viewed by 87 | Submission Open
Keywords: maternal; fetal; perinatal period; prenatal diagnosis; pregnancy
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Clinical Diagnosis and Management in Urology
edited by
submission deadline 31 Dec 2025 | Viewed by 86 | Submission Open
Keywords: minimally invasive surgery; early diagnosis; cancer biomarkers; diagnostic technology; surgical challenges; early diagnosis in urological cancers
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Diagnosis and Management of Meningitis—2nd Edition
edited by
submission deadline 31 Dec 2025 | Viewed by 78 | Submission Open
Keywords: bacterial meningitis; invasive meningococcal disease; molecular diagnostics; molecular typing; laboratory surveillance; molecular epidemiology
(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)
Advances in Pain Medicine: Diagnosis and Management
edited by Alessandro Dario
submission deadline 31 Dec 2025 | Viewed by 77 | Submission Open
Keywords: neuropathic pain; fibromialgia; low back pain; nociplastic pain; artificial intelligence in pain medicine; evidence-based consensus guidelines; pain measuring; cancer pain medicine; interventional pain medicine; topic analgesic for chronic pain; SPECT/CT scan
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Advances in the Diagnosis of Surgical Pathology
edited by Dong Ren
submission deadline 31 Dec 2025 | Viewed by 75 | Submission Open
Keywords: pathological diagnosis; diagnostic dilemma and pitfall; molecular pathology; digital pathology
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
New Advances in Digestive Endoscopy
edited by Dominique Béchade
submission deadline 31 Dec 2025 | Viewed by 74 | Submission Open
Keywords: digestive endoscopy; colonoscopy; endoscopic ultrasound; interventional endoscopy; EUS-Guided Fine-Needle Aspiration (EUS-FNA); EUS-Fine Needle Biopsy (EUS-FNB); Endoscopic Retrograde Cholangiopancreatography (ENCR)
(This special issue belongs to the Section Biomedical Optics)
Multimodal Imaging: Enhancing Precision Medicine across Diverse Clinical Pathways
edited by and Salvatore Masala
submission deadline 31 Dec 2025 | Viewed by 64 | Submission Open
Keywords: CT; XR; CT US; MRI; functional MRI; PET; SPECT
(This special issue belongs to the Section Medical Imaging and Theranostics)
New Technologies and Tools Used for Risk Assessment of Diseases
edited by
submission deadline 31 Dec 2025 | Viewed by 64 | Submission Open
Keywords: digital health; AI in healthcare; machine learning; disease risk prediction; medical imaging; wearable technology; big data analytics; telemedicine; personalized medicine; explainable AI
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Advances in the Diagnosis and Management of Neuropsychiatric Disorders—2nd Edition submission deadline 31 Dec 2025 | Viewed by 63 | Submission Open
Keywords: neuropsychiatric disorders; autism; mania; depression; imaging; diagnosis; prognosis
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Neurological Disorders: Diagnosis and Management
edited by
submission deadline 31 Dec 2025 | Viewed by 42 | Submission Open
Keywords: stroke diagnosis; treatment outcome prediction; neuroimaging; machine learning; biomarkers; personalized medicine
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Advances in Ultrasound Diagnosis in Maternal Fetal Medicine Practice
edited by , and Lau Wai-Lam
submission deadline 31 Dec 2025 | Viewed by 41 | Submission Open
Keywords: obstetric ultrasound; placenta; fetal abnormalities; color doppler
(This special issue belongs to the Section Medical Imaging and Theranostics)
Recent Advances in Genomics for Prenatal Diagnosis
edited by Wing-Cheong Leung and
submission deadline 31 Dec 2025 | Viewed by 37 | Submission Open
Keywords: prenatal diagnosis; genetics; genomics; NIPT; WES; WGS; CRISPR; epigenetics; expanded carrier screening
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Infective Endocarditis in Cardiac Prosthesis and Devices
edited by José Alberto San Román-Calvar and Javier López-Díaz
submission deadline 31 Dec 2025 | Viewed by 29 | Submission Open
Keywords: infective endocarditis; valvular surgical prosthesis; TAVRs; cardiac electronic implantable devices; left ventricular assist devices
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Innovations in Medical Imaging for Precision Diagnostics
edited by
submission deadline 31 Dec 2025 | Viewed by 29 | Submission Open
Keywords: deep learning; multimodal imaging; precision medicine; single-photon emission computed tomography (SPECT); mammography; tomosynthesis; ultrasound; neurology; oncology; medicine; psychiatry
(This special issue belongs to the Section Medical Imaging and Theranostics)
Hybrid PET/MR Imaging: Technological Advances and Multidisciplinary Clinical Applications
edited by
submission deadline 31 Dec 2025 | Viewed by 28 | Submission Open
Keywords: PET/MR; hybrid imaging; molecular imaging; diagnostic imaging; oncology; cardiology; neurology; senology; pediatrics; musculoskeletal imaging; precision medicine; clinical applications
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