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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Diagnostic Approaches for Otologic Diseases in Otolaryngology

edited by Sung-Won Choi

submission deadline 30 Sep 2026 | 3 articles | Viewed by 1527 | Submission Open

Keywords: otologic diseases; diagnostic methods; hearing loss; vestibular disorders; advanced imaging; audiovestibular testing

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Treatment of Kidney Disease—2nd Edition

edited by

Giuseppe Stefano Netti

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1464 | Submission Open

Keywords: kidney diseases; acute kidney injury; nephropathy; biomarkers; diagnosis; chronic renal failure

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Autopsy Pathology's Paradigm Shift: Are AI and New Technologies Forging a New Era?

edited by

Vincenzo Arena

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1375 | Submission Open

Keywords: autopsy pathology; AI; artificial intelligence; immunohistochemistry; molecular pathology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Frontier Exploration of Multimodal Imaging in Cardiac Rheumatic and Immune Diseases

edited by

Sophie Mavrogeni

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1340 | Submission Open

Keywords: myopericarditis; valvular heart disease; coronary artery disease; vasculitis vascular stenosis; vascular aneurysm; reynard phenomenon

Advanced Diagnostics in Women's Health: From Biomarkers to Imaging

edited by

Elena Bernad

submission deadline 30 Sep 2026 | 3 articles | Viewed by 1243 | Submission Open

Keywords: women’s health diagnostics; biomarkers; medical imaging; ultrasound; risk stratification; early diagnosis; precision medicine; obstetrics and gynaecology; non-invasive diagnostics; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Dental Imaging, 2nd Edition

edited by

Daniel Fried

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1200 | Submission Open

Keywords: dental imaging; optical coherence tomography; ultrasound; dental MRI; dental CT; cone-beam computed tomography; optical imaging; acoustic imaging; dental radiography; panoramic radiography; artificial intelligence

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Hematology Laboratory—2nd Edition

edited by

Eloisa Urrechaga

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1172 | Submission Open

Keywords: complete blood counts; leukocyte differential; reticulocyte indices; immature platelet fraction; cell population data; blood cell analyzers

(This special issue belongs to the Section Clinical Laboratory Medicine)

Recent Achievements in Oral and Maxillofacial Radiology

edited by

Svetlana Antic

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1154 | Submission Open

Keywords: cone-beam computed tomography (CBCT); artificial intelligence (AI) in radiology; maxillofacial pathology detection and evaluation; image-guided surgery; radiation dose optimization; radiographic interpretation; virtual surgical planning; temporomandibular joint imaging; temporomandibular joint and temporal bone diagnostics; oral cancer detection and evaluation

(This special issue belongs to the Section Medical Imaging and Theranostics)

Innovations in Diagnosis and Management of Cardiovascular Diseases

edited by

Marcelo Luiz Campos Vieira

and José Luiz Barros Pena

submission deadline 30 Sep 2026 | 2 articles | Viewed by 1141 | Submission Open

Keywords: diagnosis; artificial intelligence; cardiovascular diseases

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Soft Tissue and Bone Sarcomas: Advances in Diagnosis, Treatment, and Prognosis

edited by

Andrea Angelini

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1139 | Submission Open

Keywords: soft tissue sarcomas; bone sarcomas; diagnosis; prognosis; biomarkers

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Management of Pulmonary Fibrosis

edited by Yi Wang

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1131 | Submission Open

Keywords: pulmonary fibrosis; idiopathic pulmonary fibrosis; interstitial lung disease; diagnosis; biomarkers; antifibrotic therapy; imaging; disease management

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Deep Learning Applications in Medical Image Analysis and Diagnosis

edited by Jorge M. Núñez-Córdoba

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1122 | Submission Open

Keywords: deep learning; machine learning; artificial intelligence; medical imaging; diagnostic imaging; clinical validation; accuracy

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Optical Coherence Tomography in Ophthalmology: Advanced Diagnostics and Intraoperative Applications

edited by

Xiaogang Wang

submission deadline 30 Sep 2026 | 1 articles | Viewed by 893 | Submission Open

Keywords: optical coherence tomography; retinal diseases; glaucoma; intraoperative imaging; surgical guidance; diagnostic imaging; vascular imaging; anterior segment; microvasculature; blood flow

(This special issue belongs to the Section Medical Imaging and Theranostics)

Machine Learning Approaches for the Diagnosis of Sleep and Respiratory Disorders

edited by

Alaa Sheta

, Shyam Subramanian and

Salim R. Surani

submission deadline 30 Sep 2026 | 1 articles | Viewed by 822 | Submission Open

Keywords: diagnostics; artificial intelligence; sleep; respiratory disorders; healthcare

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Positron Emission Tomography Imaging for the Evaluation of the Central Nervous System

edited by

Francesco Dondi

submission deadline 30 Sep 2026 | 1 articles | Viewed by 806 | Submission Open

Keywords: PET/CT; PET; positron emission tomography; CNS; central nervous system

(This special issue belongs to the Section Medical Imaging and Theranostics)

AI-Powered Medical Image Diagnosis: From Algorithm Development to Clinical Validation

edited by

Kwang Gi Kim

submission deadline 30 Sep 2026 | 1 articles | Viewed by 780 | Submission Open

Keywords: artificial intelligence ; medical image diagnosis ; deep learning ; clinical validation ; diagnostic accuracy

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Applications of Optical Coherence Tomography in the Ocular Diagnosis: From the Tear Film to the Sclera 2.0

edited by

Claudio Iovino

Jay Chhablani

and

Giuseppe Giannaccare

submission deadline 30 Sep 2026 | 1 articles | Viewed by 707 | Submission Open

Keywords: optical coherence tomography; optical coherence tomography angiography; corneal curvature; tear film; central corneal thickness; glaucoma; anterior chamber; iris angiography; macular thickness; choroidal thickness; axial length measurement; retinal vascular plexuses; choroidal vasculature; macular surgery

(This special issue belongs to the Section Biomedical Optics)

Periodontal Disease: Diagnosis and Management, 2nd Edition

edited by

Francesco D’Ambrosio

submission deadline 30 Sep 2026 | 1 articles | Viewed by 580 | Submission Open

Keywords: periodontal disease ; periodontitis ; management ; diagnosis ; biomarker ; periodontology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Pediatric Musculoskeletal Radiology Diagnosis: From Imaging Signs to Clinical Decisions

edited by Dhouib Amira

submission deadline 30 Sep 2026 | 1 articles | Viewed by 579 | Submission Open

Keywords: pediatric bone disorders; inflammatory bone disease; musculoskeletal infection; imaging signs; advanced MRI techniques

(This special issue belongs to the Section Medical Imaging and Theranostics)

Feature Review Papers in Histopathology

edited by Dong Ren

submission deadline 30 Sep 2026 | Viewed by 542 | Submission Open

Keywords: histopathological features; histologic subtypes; diagnostic dilemma and pitfall; ancillary testing; tumor pathogenesis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Clinical Updates in Diagnosis and Management of Thrombocytopenia

edited by Maria Eva Mingot-Castellano and Cristina Pascual-Izquierdo

submission deadline 30 Sep 2026 | Viewed by 509 | Submission Open

Keywords: ITP; bleeding; thrombosis; anticoagulant; antiplatelet

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Recent Advances in Radiomics for Medical Imaging: Second Edition

edited by

Xiang Li

submission deadline 30 Sep 2026 | Viewed by 385 | Submission Open

Keywords: radiomics; PET/CT; SPECT/CT; medical imaging; cancers

(This special issue belongs to the Section Medical Imaging and Theranostics)

Clinical Advances in Diagnosis and Prognosis of Urological Diseases

edited by

Xiuheng Liu

submission deadline 30 Sep 2026 | 1 articles | Viewed by 346 | Submission Open

Keywords: urological diagnostics; prognostic biomarkers; artificial intelligence in urology; precision medicine; liquid biopsy; advanced imaging; prostate cancer; bladder cancer; kidney cancer; clinical risk stratification

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Integrative Computational Neuropathology: Multimodal Approaches for Precision Diagnosis

edited by Timothy E. van Meter

submission deadline 30 Sep 2026 | Viewed by 312 | Submission Open

Keywords: computational neuropathology; neurology; brain; spinal cord; multiplex; biomarkers; automated imaging; artificial intelligence; automated diagnosis; machine learning; precision medicine

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnostic Innovations in Metabolic Diseases Management

edited by

Teodora Alexescu

and Angela Cozma

submission deadline 30 Sep 2026 | Viewed by 304 | Submission Open

Keywords: metabolic diseases; cardio-reno-metabolic syndrome; obesity; metabolic syndrome

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

AI-Driven Innovations in Medical Imaging and Diagnostics

edited by

Xiang Li

submission deadline 30 Sep 2026 | Viewed by 250 | Submission Open

Keywords: artificial intelligence; medical imaging; diagnosis; foundation models; generative AI; clinical decision support

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Diagnostic Testing for Esophageal Diseases

edited by

Micheal Tadros

submission deadline 30 Sep 2026 | Viewed by 246 | Submission Open

Keywords: esophageal diseases; endoscopy; diagnostic tools; diagnostic testing; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Laboratory Diagnosis of Cardiovascular Diseases

edited by Ibrahim A. Hashim

submission deadline 30 Sep 2026 | Viewed by 243 | Submission Open

Keywords: laboratory diagnostics; cardiovascular diseases; biomarkers; metabolomics; point-of-care testing; artificial intelligence

(This special issue belongs to the Section Clinical Laboratory Medicine)

Recent Advancements in the Diagnosis and Prognosis of Thoracic Diseases

edited by Marco Andolfi

submission deadline 30 Sep 2026 | Viewed by 233 | Submission Open

Keywords: quality of life; risk stratification; thoracic diseases; circulating biomarkers; tissue biomarkers

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Diagnostic Modalities for Benign Upper Gastrointestinal Disorders

edited by Gad Marom and Daniel Solomon

submission deadline 30 Sep 2026 | Viewed by 193 | Submission Open

Keywords: upper gastrointestinal tract; benign disorders; endoscopy; high resolution manometry; computerized tomography; barium swallow study; EndoFLIP

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advanced Electrocardiogram for Clinical Applications

edited by Francesco Luzza

submission deadline 30 Sep 2026 | Viewed by 184 | Submission Open

Keywords: cardiac electrophysiology; atrial fibrillation; arrhythmias; ventricular tachycardia; brugada pattern; QT interval; early repolarization; sudden cardiac death; myocardial ischemia; cardiomyopathies

(This special issue belongs to the Section Medical Imaging and Theranostics)

Sarcoidosis: Current Landscape and Future Developments

edited by

Ilias C. Papanikolaou

and Fotios Drakopanagiotakis

submission deadline 30 Sep 2026 | Viewed by 163 | Submission Open

Keywords: sarcoidosis; diagnosis; prognosis; biomarkers; imaging; histopathology; clinical presentation; diagnostic criteria; multidisciplinary approach; treatment; treatment algorithm

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Ocular Inflammation: Progress and Pitfalls in Diagnosis, Imaging and Management

edited by

Carl P. Herbort, Jr.

and

Ioannis Papasavvas

submission deadline 1 Oct 2026 | 2 articles | Viewed by 882 | Submission Open

Keywords: uveitis; intraocular inflammation; fluorescein angiography (FA); indocyanine green angiography (ICGA); optical coherence tomography (OCT); enhanced depth imaging OCT (EDI-OCT); optical coherence tomography angiography (OCT-A); fundus autofluorescence (FAF); uveitis masquerades; intraocular interleukin assays; Vogt–Koyanagi–Harada disease (VKH); multiple evanescent white dot syndrome (MEWDS); consensus definitions

(This special issue belongs to the Section Medical Imaging and Theranostics)

AI for Precision Diagnostics: Enhancing Accuracy, Accessibility, and Outcomes

edited by

Shereen Afifi

and Mirza Mansoor Baig

submission deadline 30 Oct 2026 | 9 articles | Viewed by 6944 | Submission Open

Keywords: precision diagnostics; medical imaging and radiology; machine learning, deep learning, and transformers; biosensors and wearable health devices; explainable AI; point-of-care and remote diagnostic systems; digital health; edge AI and computing; bioinformatics; personalized medicine and health; healthcare accessibility

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Beyond the Joint: Advances in Musculoskeletal Imaging and Sports Radiology

edited by

Francesco Feletti

submission deadline 30 Oct 2026 | Viewed by 418 | Submission Open

Keywords: sports radiology; musculoskeletal imaging; diagnostic imaging; artificial intelligence; orthopaedics; extreme sports; outdoor sports; outdoor physical activity; one health; health policy

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in the Diagnosis and Treatment of Infections of the Central Nervous System

edited by

Teresa Perillo

and Raffaella Capasso

submission deadline 31 Oct 2026 | 2 articles | Viewed by 29941 | Submission Open

Keywords: central nervous system infections; meningitis; HIV; tuberculosis; magnetic resonance imaging

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Computed Tomography Imaging for Clinical Diagnosis—2nd Edition

edited by Ibrahim Yel

submission deadline 31 Oct 2026 | 8 articles | Viewed by 16647 | Submission Open

Keywords: computed tomography imaging; clinical diagnosis; dual-energy CT; photon-counting CT; image analysis

(This special issue belongs to the Section Medical Imaging and Theranostics)

Challenges in Monitoring and Diagnosis in Medical Sciences

edited by

Mihaela Badea

and

Laura Gaman

submission deadline 31 Oct 2026 | 5 articles | Viewed by 13319 | Submission Open

Keywords: diagnostic; monitoring; medical sciences

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Ovarian Cancer in 2025–2026: A Comprehensive Look at Characteristics, Screening, Diagnosis and Treatment

edited by

Edward J. Pavlik

submission deadline 31 Oct 2026 | 3 articles | Viewed by 8755 | Submission Open

Keywords: ovarian cancer; risk; treatment; detection; screening; trial design; treatment; collateral effects; endpoints; costs; efficacy; AI; sojourn time models; vaccines; PARP inhibitors; liquid biopsies; post treatment hematologic malignancies; HIPEC; STIC/STIL

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Updates in Vascular and Endovascular Surgery: Pathology, Diagnosis and Management

edited by Ombretta Martinelli and

Antonio Marzano

submission deadline 31 Oct 2026 | 7 articles | Viewed by 7949 | Submission Open

Keywords: aneurysms of the aorta; aneurysms of the arch; arterial stenosis; EVAR (endovascular aneurysm repair); FEVAR (fenestrated endovascular aneurysm repair); BEVAR (branched endovascular aneurysm repair); iliac branches; varicose veins; venous insufficiency; chronic obstructive arteriopathy

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Prognosis of Abdominal Diseases

edited by

Filippo Carannante

submission deadline 31 Oct 2026 | 6 articles | Viewed by 7707 | Submission Open

Keywords: diagnosis; prognosis; abdominal diseases; markers; screening

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Integrative Approaches in Head and Neck Cancer Imaging

edited by

Calin G. Buzea

submission deadline 31 Oct 2026 | 3 articles | Viewed by 7284 | Submission Open

Keywords: head and neck cancer; imaging technologies; multimodal imaging; image-guided therapy; artificial intelligence in imaging

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

New Insights into Gastrointestinal Endoscopy

edited by

Paraskevas Gkolfakis

and

Apostolis Papaefthymiou

submission deadline 31 Oct 2026 | 4 articles | Viewed by 5863 | Submission Open

Keywords: diagnosis; prognosis; gastrointestinal endoscopy; markers; clinical practice and patient care

(This special issue belongs to the Section Biomedical Optics)

Diagnosis and Management of Liver Diseases, Third Edition

edited by

Jeong-Ju Yoo

submission deadline 31 Oct 2026 | 4 articles | Viewed by 5711 | Submission Open

Keywords: liver diseases; fatty liver; liver cirrhosis; viral hepatitis; hepatocellular carcinoma; diagnosis and management

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Recent Advances in the Diagnosis and Prognosis of Lung Cancer

edited by Naomi Takemura

submission deadline 31 Oct 2026 | 4 articles | Viewed by 5321 | Submission Open

Keywords: lung cancer; molecular biomarkers; artificial intelligence; early detection; precision detection; medical imaging

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Pathology for Forensic Diagnosis

edited by

Cristina Mondello

and Vincenzo Cianci

submission deadline 31 Oct 2026 | 5 articles | Viewed by 5264 | Submission Open

Keywords: forensic pathology; forensic medicine; forensic radiology; forensic genetics; forensic toxicology; postmortem interval; forensic odontology; forensic entomology; forensic anthropology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Clinical Diagnosis and Prognosis of Steatotic Liver Disease

edited by

Helma Pinchemel Cotrim

submission deadline 31 Oct 2026 | 4 articles | Viewed by 4995 | Submission Open

Keywords: steatotic liver disease—SLD; steatohepatitis; steatosis; diagnosis; prognosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnostic and Prognostic Non-Invasive Markers in Bladder Cancer

edited by

Qiang Lv

and Xiao Yang

submission deadline 31 Oct 2026 | 6 articles | Viewed by 4543 | Submission Open

Keywords: bladder cancer; diagnostic and prognostic markers; non-invasive; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Optical Coherence Tomography in Non-Invasive Diagnostic Imaging

edited by

Carmen Cantisani

and

Sandra Schuh

submission deadline 31 Oct 2026 | 3 articles | Viewed by 4418 | Submission Open

Keywords: diagnosis; screening; marker; prognosis; optical coherence tomography; non-invasive diagnostic imaging

(This special issue belongs to the Section Biomedical Optics)

Advances in Oral Pathology of Basic and Clinical Cancer Research

edited by

Jun-Ichi Tanuma

submission deadline 31 Oct 2026 | 5 articles | Viewed by 4315 | Submission Open

Keywords: oral cancer; molecular pathology; tumor microenvironment (TME); immunotherapy; epigenetics; diagnosis; targeted therapy; personalized medicine; AI and image analysis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

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