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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Novel Approaches for Artificial Intelligence in Neuroimaging Applications, 2nd Edition

edited by

Kwang-Sig Lee

submission deadline 28 Feb 2026 | Viewed by 126 | Submission Open

Keywords: neuroimaging; machine learning; deep learning; explainable artificial intelligence; SHAP; GradCAM; generative artificial intelligence; BERT; GPT; multi-modal reinforcement learning

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

New Mechanistic Insights in Arrhythmia: Implications for Diagnosis and Targeted Therapy

edited by

Radu Gabriel Vătăşescu

and

Alexandru Deaconu

submission deadline 28 Feb 2026 | Viewed by 124 | Submission Open

Keywords: arrhythmia mechanisms; personalized medicine; risk stratification; ablation therapy; cardiac mapping

Laboratory Testing in Endocrine Diseases

edited by

Aw Tar-Choon

and Chin Shern Lau

submission deadline 28 Feb 2026 | Viewed by 120 | Submission Open

Keywords: endocrine diseases; laboratory testing; clinical correlation; hormone testing; diagnosis and management

(This special issue belongs to the Section Clinical Laboratory Medicine)

Advances in the Diagnostics and Management of Diseases of the Anterior Segment of the Eye

edited by

Sang Beom Han

submission deadline 28 Feb 2026 | Viewed by 109 | Submission Open

Keywords: anterior segment disorder; cornea; cataract; anterior segment imaging; refractive surgery

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Echocardiography Diagnostics

edited by Hatem Soliman Aboumarie

submission deadline 28 Feb 2026 | Viewed by 107 | Submission Open

Keywords: echocardiography innovations; cardiac imaging advancements; strain echocardiography; 3D/4D cardiac ultrasound

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnostic Innovations in Resuscitation and Emergency Medicine: From Biomarkers to Point-of-Care Technologies

edited by Theodoros T. Xanthos

submission deadline 28 Feb 2026 | Viewed by 106 | Submission Open

Keywords: point-of-care ultrasound; cardiac arrest; diagnostic biomarkers; cardiac or neurological injury; time-sensitive interventions

(This special issue belongs to the Section Point-of-Care Diagnostics and Devices)

Emerging Diagnostic Technologies in Orthopedics: Advancing Personalized Implant Design and Therapeutics

edited by

Neil Ashwood

submission deadline 28 Feb 2026 | Viewed by 104 | Submission Open

Keywords: patient-specific implant design; advanced diagnostic technologies; computational biomechanics; surgical navigation systems; implant manufacturing; intraoperative monitoring; postoperative evaluation; biomedical engineering; clinical implant optimization; precision medicine

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Thrombosis Diagnosis and Antithrombotic Therapy

edited by Ovidio De Filippo,

Fabrizio D’Ascenzo

and Francesco Antonio Veneziano

submission deadline 28 Feb 2026 | Viewed by 103 | Submission Open

Keywords: antithrombotic therapy; ischemic heart disease; risk stratification; personalized medicine; dual antiplatelet therapy; bleeding risk; coronary artery disease; artificial intelligence

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Rare Cancers: Improving Diagnosis and Prognosis Through Collaborative Research

edited by Chen-Wang Chang

submission deadline 28 Feb 2026 | Viewed by 103 | Submission Open

Keywords: rare cancer; diagnosis and prognosis; biomarker; early detection; precision medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Precision Diagnostics in Gynecologic Health and Disease

edited by

Ayse Ayhan

submission deadline 28 Feb 2026 | Viewed by 99 | Submission Open

Keywords: gynecologic diseases; diagnostic imaging; pathology; molecular diagnostic techniques; biomarkers; artificial intelligence; endometriosis; adenomyosis; precision medicine; minimally invasive surgery

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnostics in Oncology Research

edited by Riffat Mehboob

submission deadline 14 Mar 2026 | 1 articles | Viewed by 1554 | Submission Open

Keywords: oncology diagnostics; cancer detection; precision medicine; tumor biomarkers; digital pathology; artificial intelligence in oncology; epigenetic biomarkers; immunohistochemical biomarkers; predictive modeling; genomic profiling; transcriptome signature; PET/CT and MRI diagnostics; machine learning for cancer diagnostics

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Deep Learning Techniques for Medical Image Analysis

edited by

Zhuhuang Zhou

submission deadline 15 Mar 2026 | 9 articles | Viewed by 23735 | Submission Open

Keywords: deep learning; supervised learning; unsupervised learning; semi-supervised learning; self-supervised learning; generative learning; deep neural networks; convolutional neural networks; physics-informed neural networks; X-ray imaging; computed tomography (CT); magnetic resonance imaging (MRI); ultrasound imaging; ultrasound computed tomography; functional MRI; positron emission tomography (PET); single-photon emission computed tomography (SPECT); functional ultrasound imaging; image reconstruction

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Research Updates in Vestibular Dysfunction: Diagnostic Breakthroughs

edited by

Jun Wang

and

Sulin Zhang

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1103 | Submission Open

Keywords: vestibular disorders; vertigo; biomarkers; molecular diagnostics; vestibular compensation; Meniere’ s disease; BPPV; vestibular migraine; PPPD; dizziness; balance

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnostic Tools and Monitoring Strategies for Chronic Diseases: Integrating Patient-Reported Outcomes to Enhance Clinical Decision-Making

edited by Vladimir Poroch

submission deadline 25 Mar 2026 | Viewed by 101 | Submission Open

Keywords: quality of life; chronic diseases; patient-reported outcome measures; patient-reported experience measures; supportive interventions; multidisciplinary and holistic approach; symptom control; healthcare accessibility; burden of care prevention; digital health tools; palliative care

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Dental Imaging

edited by

Daniel Fried

submission deadline 31 Mar 2026 | 17 articles | Viewed by 85003 | Submission Open

Keywords: dental imaging; optical coherence tomography; ultrasound; dental MRI; dental CT; cone-beam computed tomography; optical imaging; acoustic imaging; dental radiography; panoramic radiography; artificial intelligence

(This special issue belongs to the Section Medical Imaging and Theranostics)

Clinical Characteristics of Headache and Diagnosis of Primary and Secondary Headache Disorders

edited by

Elena R. Lebedeva

submission deadline 31 Mar 2026 | 9 articles | Viewed by 52110 | Submission Open

Keywords: primary headache disorders; secondary headache disorders; migraine-like headache; tension-type headache; migraine; headache; characteristics of headache

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Trends in In Vitro Diagnostics Paving the Way to Next-Generation Healthcare

edited by

Sandeep K. Vashist

submission deadline 31 Mar 2026 | 8 articles | Viewed by 31093 | Submission Open

Keywords: IVDs (in vitro diagnostics); POCT (point-of-care testing); LFA (lateral flow assay); CLIA (clinical laboratory improvement amendments); multiplex assays; PCR; NGS (next-generation sequencing); AI; at-home testing; biomarkers; smart technologies

(This special issue belongs to the Section Point-of-Care Diagnostics and Devices)

Clinical Diagnosis and Management in Cardiology

edited by

Oskars Kalejs

submission deadline 31 Mar 2026 | 15 articles | Viewed by 25509 | Submission Open

Keywords: cardiology; heart disease; arrhythmia; myocardial infarction; angina pectoris; coronary artery disease; echocardiography

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Kidney Disease: Biomarkers, Diagnosis, and Prognosis: 3rd Edition

edited by

Akito Maeshima

submission deadline 31 Mar 2026 | 5 articles | Viewed by 25315 | Submission Open

Keywords: primary/secondary glomerulonephritis; rapidly progressive glomerulonephritis; nephrotic syndrome; acute kidney injury; chronic kidney disease; diabetic nephropathy/diabetic kidney disease; chronic renal failure; kidney transplantation; renal fibrosis; polycystic kidney

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Clinical Diagnosis and Management in Orthopaedics and Traumatology

edited by Attilio Basile

submission deadline 31 Mar 2026 | 6 articles | Viewed by 11452 | Submission Open

Keywords: joint replacement; surgical navigation; outcome assessment; fracture repair; imaging technologies

(This special issue belongs to the Section Medical Imaging and Theranostics)

Artificial Intelligence in Biomedical Imaging and Signal Processing

edited by Olusola Oluwakemi Abayomi-Alli,

Olamilekan Shobayo

and

Modupe Odusami

submission deadline 31 Mar 2026 | 6 articles | Viewed by 11299 | Submission Open

Keywords: medical image processing; healthcare; artificial intelligence; machine learning; deep learning; computer vision; AI-assisted; explainable ai; segmentation; augmentation; multimodal fusion

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Diagnosis and Management of Oral Disorders

edited by

Jyothi Tadakamadla

submission deadline 31 Mar 2026 | 8 articles | Viewed by 11016 | Submission Open

Keywords: oral disease; biomarker; prognosis; periodontal disease; machine learning; MRI; CBCT

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advancing Clinical Diagnosis with Artificial Intelligence: Applications, Challenges, and Future Directions

edited by

Haipeng Liu

Rajesh K. Tripathy

, Shonak Bansal and

Prince Jain

submission deadline 31 Mar 2026 | 5 articles | Viewed by 7927 | Submission Open

Keywords: deep learning; artificial intelligence (AI); internet of medical things (IoMT); AI-assisted diagnostics; multimodal clinical data; data-driven healthcare

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Insights into Perinatal Medicine and Fetal Medicine—2nd Edition

edited by Paola Quaresima and Ilaria Fantasia

submission deadline 31 Mar 2026 | 6 articles | Viewed by 7141 | Submission Open

Keywords: fetal malformations; hypertensive disorders of pregnancy; gestational diabetes; fetal growth; in utero surgery; first-trimester screening; fetal aneuploidies

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Insights into Pediatric Genetics

edited by

Chunglin Lee

submission deadline 31 Mar 2026 | 6 articles | Viewed by 6213 | Submission Open

Keywords: pediatric genetics; genetic sequencing; rare disorders; genetic diagnosis; precision medicine

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Recent Advances in Gynecologic Oncology: Diagnosis and Management, 2nd Edition

edited by

Jure Knez

submission deadline 31 Mar 2026 | 3 articles | Viewed by 5869 | Submission Open

Keywords: endometrial cancer; ovarian cancer; cervical cancer; vulvar cancer; ultrasound; colposcopy; diagnosis and management

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advancements in Interventional Radiology Techniques in Vascular and Extravascular Diseases

edited by

Francesco Giurazza

and

Fabio Corvino

submission deadline 31 Mar 2026 | 6 articles | Viewed by 5688 | Submission Open

Keywords: embolization; radial; oncology; radioembolization; ablation; chemoembolization

(This special issue belongs to the Section Medical Imaging and Theranostics)

Cerebrovascular Lesions: Diagnosis and Management, 2nd Edition

edited by

Hung-Chieh Chen

submission deadline 31 Mar 2026 | 5 articles | Viewed by 5250 | Submission Open

Keywords: stroke; aneurysm; vascular malformation; computed tomography (CT); magnetic resonance imaging (MRI)

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in the Diagnosis and Management of Musculoskeletal Diseases and Bone Fracture Risk

edited by Paola Pisani

submission deadline 31 Mar 2026 | 4 articles | Viewed by 4664 | Submission Open

Keywords: musculoskeletal diseases; bone mineral density; fracture risk; metabolic bone disorders; REMS technology

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Imaging Diagnosis of Dermatology

edited by Linda Tognetti

submission deadline 31 Mar 2026 | 4 articles | Viewed by 4196 | Submission Open

Keywords: high-resolution imaging; non-invasive diagnosis; LC-OCT; RCM; OCT; US

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Pediatric Cardiology: Diagnosis and Management

edited by Federico Gutiérrez-Larraya

submission deadline 31 Mar 2026 | 3 articles | Viewed by 4051 | Submission Open

Keywords: pediatric cardiology; pediatric heart diseases; congenital heart disease; echocardiography; MRI

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advanced Ultrasound Techniques in Diagnosis

edited by

Laith Riyadh Sultan

submission deadline 31 Mar 2026 | 4 articles | Viewed by 4047 | Submission Open

Keywords: super-resolution imaging; microvascular imaging (MVI); contrast-enhanced ultrasound; AI-guided ultrasound; quantitative analysis; diagnostic imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Utilization of Liquid Biopsy in Cancer Diagnosis and Management 2025

edited by

Consolato M. Sergi

submission deadline 31 Mar 2026 | 1 articles | Viewed by 3871 | Submission Open

Keywords: liquid biopsy; precision medicine; cancer diagnostics; nanotechnologies; markers

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Clinical Prognostic and Predictive Biomarkers, Third Edition

edited by

Yuli Huang

and

Peisong Chen

submission deadline 31 Mar 2026 | 2 articles | Viewed by 3637 | Submission Open

Keywords: biomarkers; prognostic; predictive; risk stratification; cardiovascular disease; diabetes; cancer; hypertension; heart failure

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Recent Advances in Pathology 2025

edited by

Francesca Sanguedolce

and

Roberta Mazzucchelli

submission deadline 31 Mar 2026 | Viewed by 2677 | Submission Open

Keywords: pathology innovations; molecular diagnostics; biomarkers and precision medicine; digital pathology; artificial intelligence in pathology; translational pathology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Artificial Intelligence in Diagnostics: From Algorithms to Clinical Impact

edited by

Ali Athar

, David Brown and

Hanem Ellethy

submission deadline 31 Mar 2026 | 3 articles | Viewed by 2472 | Submission Open

Keywords: machine learning in healthcare; artificial intelligence in diagnostics; medical imaging and deep learning; generative AI in medicine; multimodal data integration; explainable and trustworthy AI; translational medical AI; clinical decision support systems; secure and privacy-compliant data utilization

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Diagnostic Approaches to Assessing Physical Activity in Pregnancy: Monitoring Maternal Physiology and Birth Outcomes

edited by

María Mar Gil

and Aránzazu Martín-Arias

submission deadline 31 Mar 2026 | 1 articles | Viewed by 2406 | Submission Open

Keywords: diagnostics; pregnancy; maternal physiology and birth outcomes; biomarkers; prenatal care

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Exploring Circadian Clock Effects on Disease Diagnosis, Progression, and Therapeutic Approaches

edited by Baharan Fekry

submission deadline 31 Mar 2026 | 1 articles | Viewed by 2403 | Submission Open

Keywords: circadian clocks; circadian rhythm disorders; diagnosis; management

(This special issue belongs to the Section Clinical Laboratory Medicine)

Hot Topics in Modern and Personalized Pathology

edited by

Sergejs Isajevs

submission deadline 31 Mar 2026 | 3 articles | Viewed by 2109 | Submission Open

Keywords: personalized diagnostics and tissue biomarkers; molecular pathology; digital pathology; oncological pathology; and rare cancer studies; tumor diagnostics and tumor biomarkers; immunohistochemistry; molecular and ultrastructural pathology; laboratory medicine

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Molecular Techniques in Infectious Disease Diagnosis: Advances and Applications

edited by

Peisong Chen

submission deadline 31 Mar 2026 | 2 articles | Viewed by 1925 | Submission Open

Keywords: molecular diagnostics; PCR; NGS; CRISPR; antimicrobial resistance; point-of-care testing; metagenomics; pathogen detection

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Molecular Diagnosis and Medical Management of Cardiovascular Diseases

edited by

Yiqing Yang

submission deadline 31 Mar 2026 | 2 articles | Viewed by 1742 | Submission Open

Keywords: cardiovascular disease; congenital heart disease; coronary artery disease; arrhythmia; cardiomyopathy; essential hypertension; stroke; molecular genetics; epidemiology; biomarkers

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Diagnosis and Management of Endometrial Diseases

edited by

Kotaro Kitaya

submission deadline 31 Mar 2026 | 2 articles | Viewed by 1626 | Submission Open

Keywords: endometrial diseases; artificial intelligence; hysteroscopy; ultrasound; minimally invasive surgery

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

New Insights into Endoscopy-Guided Diagnosis

edited by

Haruo Miwa

submission deadline 31 Mar 2026 | 2 articles | Viewed by 1602 | Submission Open

Keywords: gastrointestinal disease; pancreatobiliary disease; magnifying endoscope; endoscopic ultrasonography; peroral cholangiopancreatography; endo-hepatology; artificial intelligence

(This special issue belongs to the Section Medical Imaging and Theranostics)

Updates on the Diagnosis and Management of Retinal Diseases—2nd Edition

edited by

Sandra Hoyek (Alhoyek)

submission deadline 31 Mar 2026 | 2 articles | Viewed by 1593 | Submission Open

Keywords: retinal diseases; pediatric retina; Retinopathy of Prematurity (ROP); optical coherence tomography (OCT); optical coherence tomography angiography (OCTA); artificial intelligence; telemedicine; imaging biomarkers; health disparities

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Endocrine System Disease: Diagnosis and Management

edited by

Kwangsoon Kim

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1591 | Submission Open

Keywords: endocrine system disease; hormonal imbalance; diagnosis; hormone replacement therapy; pathophysiology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Recent Advances in AI and Hyperspectral Techniques for Medical Imaging

edited by

Hsianmin Chen

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1572 | Submission Open

Keywords: AI in medical imaging; hyperspectral medical imaging; biomedical image processing; deep learning; image segmentation and classification; multimodal imaging; intelligent diagnostic systems; tissue characterization; spectral imaging in medicine; clinical applications of AI and HSI

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Functional and Structural MR Image Analysis

edited by

Xingfeng Li

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1382 | Submission Open

Keywords: functional MRI; structural MRI; image analysis; radiomics; machine learning

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis in Dermatology and Venereology

edited by

Francesca Ambrogio

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1356 | Submission Open

Keywords: dermatological diagnosis; venereal disease diagnosis; skin disorders; sexually transmitted infections (STIs); clinical manifestations; diagnostic techniques

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Microbiology Laboratory: Sample Collection and Diagnosis Advances, 2nd Edition

edited by James P. Chambers and

Luke T. Daum

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1342 | Submission Open

Keywords: qPCR; NGS; sample collection; nucleic acid testing; rapid antigen testing; infectious diseases; virology; sequencing; point-of-care; diagnostics; bacteriology diagnosis; biosensors

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

The Cutting Edge of Diagnosis and Treatment in Rheumatologic Disorders

edited by Ji-Hyoun Kang

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1158 | Submission Open

Keywords: antiphospholipid syndrome (APS); hemolytic anemia; lupus anticoagulant; rheumatologic disorders; biomarkers

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Displaying special issue 251-300 on page 6 of 14.

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