Advances in the Diagnosis and Management of Musculoskeletal Diseases and Bone Fracture Risk

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Clinical Diagnosis and Prognosis".

Deadline for manuscript submissions: 31 March 2026 | Viewed by 196

Special Issue Editor


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Guest Editor
Istituto di Fisiologia Clinica del CNR, Pisa, Italy
Interests: musculoskeletal diseases; bone mineral density; fracture risk; metabolic bone disorders; REMS technology

Special Issue Information

Dear Colleagues, 

We are pleased to invite you to contribute to the Special Issue “Advances in the Diagnosis and Management of Musculoskeletal Diseases and Bone Fracture Risk”. The diagnosis and management of musculoskeletal diseases and fracture risk require a multifaceted approach that combines clinical expertise with advanced technological tools. In this field, the development of new technologies for safer and more accurate diagnoses is paving the way for more precise, effective, and personalized approaches to the management of relevant diseases, ultimately improving patient care and quality of life. The goal is to early detect the target disorders, accurately assessing their severity, and guiding the choice of the most appropriate therapeutic strategies. In light of these considerations, this Special Issue aims to stimulate the exchange of ideas and knowledge on recent advanced tools for the diagnosis, prevention, treatment, monitoring, and management of several musculoskeletal diseases. The submission of original contributions containing clinical trials, clinical cases, or state-of-the-art reviews is encouraged by research groups active in the field. 

Dr. Paola Pisani
Guest Editor

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Keywords

  • musculoskeletal diseases
  • bone mineral density
  • fracture risk, metabolic bone disorders
  • REMS technology

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Published Papers (1 paper)

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Research

12 pages, 3622 KiB  
Article
Assessing Supraspinatus Tendon Elasticity at Different Locations and Loading Conditions Using Ultrasound Shear-Wave Elastography in Young Healthy Population
by Arash Azhideh, Peyman Mirghaderi, Sara Haseli, William D. Lack, Karen C. Takatani, Liisa C. Hammer, Kevin F. Malik, Hannah Tifft, Kyle Griffith and Majid Chalian
Diagnostics 2025, 15(9), 1132; https://doi.org/10.3390/diagnostics15091132 - 29 Apr 2025
Abstract
Objective: This prospective study aims to investigate the feasibility of Shear-Wave Elastography (SWE) for assessing the mechanical properties of the normal supraspinatus tendon and describing the elastographic features of the supraspinatus tendon under different loading conditions and positions. Methods: Twenty healthy [...] Read more.
Objective: This prospective study aims to investigate the feasibility of Shear-Wave Elastography (SWE) for assessing the mechanical properties of the normal supraspinatus tendon and describing the elastographic features of the supraspinatus tendon under different loading conditions and positions. Methods: Twenty healthy volunteers (10 males and 10 females, aged 18–25 years) were examined by SWE using an 18-4 MHz linear array transducer. The elasticity of the supraspinatus tendon of the dominant hand was measured at three distinct locations: the insertion, middle, and myotendinous junction of the tendon. These measurements were taken under various conditions, including non-loading and the application of 5, 10, and 20 lb forces at five different positions. Results: The average elasticity was 69.2 ± 26.5 kilopascals across all positions and forces, with the middle part of the tendon exhibiting the highest elasticity (72.6 ± 6.2 kPa). An ascending trend in elasticity was observed by increasing the applied load, and the highest elasticity was observed with a 20 lb load. Determining the normal elasticity of the tendon is an important clinical implication, as understanding what is normal is essential for identifying pathological conditions. Conclusions: SWE is a feasible and promising technology for the collection of data on how the supraspinatus tendon behaves under loading conditions. There is a need for further study to better understand tendon response to activity and resultant injuries. Full article
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