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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Medical Image Enhancement and Quantitative Evaluation

edited by

Youngjin Lee

submission deadline 30 Apr 2027 | Viewed by 195 | Submission Open

Keywords: medical image denoising and deblurring; medical image processing; general X-ray radiography; computed tomography; magnetic resonance imaging; ultrasound; artificial intelligence; deep learning; quantitative evaluation of image quality; radiation dose

(This special issue belongs to the Section Medical Imaging and Theranostics)

Emerging Technologies in Clinical Diagnostics: From Molecular Testing to Digital Pathology

edited by Kyoung-Ryul Lee, Tae Hyun Hwang and Jung Kyoon Choi

submission deadline 30 Apr 2027 | Viewed by 60 | Submission Open

Keywords: digital pathology; molecular diagnostics; whole-slide imaging (WSI); artificial intelligence; deep learning; multi-omics; spatial biology; companion diagnostics; precision medicine; telepathology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Interventional Radiology in 2027: From Technological Innovation to Clinical Optimization

edited by

Francesco Giurazza

submission deadline 30 Apr 2027 | Viewed by 47 | Submission Open

Keywords: emergency; oncology; arterial; vascular diseases; extravascular bleedings; aneurysms; vascular malformations; neurointerventions; diagnostics; prognosis; interventional radiology

(This special issue belongs to the Section Medical Imaging and Theranostics)

Clinical and Preclinical Advances in Diabetic Comorbidities and Complications

edited by Yun Qian,

Zheng Wang

and Yizhong Peng

submission deadline 30 Apr 2027 | Viewed by 40 | Submission Open

Keywords: diabetic complications; diabetic comorbidities; translational research; biomarkers and precision medicine; diabetic wound; diabetic nephropathy; diabetic neuropathy; diabetic retinopathy; diabetic foot ulcer; pathophysiological mechanisms

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Reproductive Medicine: State of the Art in Diagnosis and Emerging Perspectives

edited by

Diego Manavella

submission deadline 30 Apr 2027 | Viewed by 40 | Submission Open

Keywords: reproductive medicine; infertility; artificial intelligence; embryo selection; oncofertility; reproductive endocrinology; diagnostic technologies; biomarkers; assisted reproductive technology (ART)

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Shaping the Future of Dermatology with Artificial Intelligence

edited by Neil K. Jairath

submission deadline 30 Apr 2027 | Viewed by 34 | Submission Open

Keywords: artificial intelligence in dermatology; deep learning in skin cancer detection; dermoscopy image analysis; convolutional neural network dermatology; teledermatology; algorithmic bias; skin of color; dermatopathology automation; clinical decision support in dermatology; generative AI dermatology; digital health equity

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Integrative Diagnostics and Management of Spine Disorders

edited by

Masato Tanaka

submission deadline 17 May 2027 | Viewed by 170 | Submission Open

Keywords: MRI; CT; AI; navigation; minimally invasive; robotics

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Precision Diagnosis and Target Delineation in Modern Radiation Oncology

edited by

Andrea D'Aviero

and Iorio Giuseppe Carlo

submission deadline 30 May 2027 | Viewed by 478 | Submission Open

Keywords: radiation oncology; target volume delineation; multimodality imaging; radiomics; artificial intelligence (AI); molecular biomarkers; image-guided adaptive radiotherapy; quantitative imaging; precision diagnostics; omics guided radiotherapy

(This special issue belongs to the Section Medical Imaging and Theranostics)

Endoscopic Diagnostics for Pancreatobiliary Disorders 2025–2026

edited by

Masataka Kikuyama

submission deadline 31 May 2027 | 6 articles | Viewed by 11283 | Submission Open

Keywords: endoscopic ultrasonography; endoscopic retrograde cholangiopancreatography; EUS–FNA; SPACE; pancreatic cancer; bile duct caner; gallbladder cancer

(This special issue belongs to the Section Biomedical Optics)

State of the Art in the Diagnosis and Management of Endocrine Tumors

edited by Milan D. Jovanović

submission deadline 31 May 2027 | 9 articles | Viewed by 7616 | Submission Open

Keywords: thyroid; parathyroid; adrenal; neuroendocrine tumors

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Molecular Diagnostics in Cardiovascular Diseases: From Biomarkers to Personalized Medicine

edited by Otilia Țica

submission deadline 31 May 2027 | 2 articles | Viewed by 6647 | Submission Open

Keywords: cardiovascular disease; biomarkers; precision medicine; diagnostics; heart failure

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnostic Challenges in Sports Cardiology—2nd Edition

edited by

Łukasz A. Małek

submission deadline 31 May 2027 | 3 articles | Viewed by 5949 | Submission Open

Keywords: sports cardiology; MRI; echocardiography; heart rate

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advanced Neuroimaging Analysis: From Data to Diagnosis

edited by

Igor Petrušić

submission deadline 31 May 2027 | 4 articles | Viewed by 5372 | Submission Open

Keywords: neuroimaging analysis ; multimodal integration ; multimodal imaging ; biomarkers ; diagnostic pipelines ; clinical translation ; neurological disorders

(This special issue belongs to the Section Medical Imaging and Theranostics)

From Data to Decisions: Deep Learning in Clinical Diagnostics

edited by Jianfu Li

submission deadline 31 May 2027 | 3 articles | Viewed by 5064 | Submission Open

Keywords: deep learning; clinical diagnostics; medical AI; diagnostic accuracy; clinical decision support; medical imaging; biomarker discovery; healthcare implementation

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Artificial Intelligence in Health Monitoring and Diagnosis: AI Meets Conventional Models—2nd Edition

edited by

Stanislav Makhanov

submission deadline 31 May 2027 | 7 articles | Viewed by 4792 | Submission Open

Keywords: artificial intelligence; medical image processing; deep learning; machine learning; diagnostics; health monitoring

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Diagnostic Imaging for Cerebrovascular Diseases

edited by Hiroaki Neki

submission deadline 31 May 2027 | 3 articles | Viewed by 3914 | Submission Open

Keywords: cerebrovascular diseases; diagnostic imaging; perfusion imaging; hemodynamic assessment; radiomics; artificial intelligence (AI); imaging biomarkers; follow-up protocols

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis and Management of Retinopathy—2nd Edition

edited by

Joanna Gołȩbiewska

submission deadline 31 May 2027 | 3 articles | Viewed by 3482 | Submission Open

Keywords: diabetic retinopathy; hypertensive retinopathy; inherited retinal diseases; imaging; OCT

(This special issue belongs to the Section Medical Imaging and Theranostics)

New Technologies in Oral Medicine: From Molecular Pathology to Clinical Practice—2nd Edition

edited by

Stefano Gennai

Marco Nisi

and

Rossana Izzetti

submission deadline 31 May 2027 | 1 articles | Viewed by 3247 | Submission Open

Keywords: oral medicine; molecular pathology; clinical dentistry; periodontics; orthodontics

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Artificial Intelligence in Pathological Image Analysis, 3rd Edition

edited by

Masayuki Tsuneki

submission deadline 31 May 2027 | 1 articles | Viewed by 3042 | Submission Open

Keywords: deep learning; artificial intelligence; cancer; pathology; molecular pathology; histopathology; cytopathology

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Diagnostic Tools and Monitoring Strategies for Chronic Diseases: Integrating Patient-Reported Outcomes to Enhance Clinical Decision-Making

edited by Vladimir Poroch

submission deadline 31 May 2027 | 2 articles | Viewed by 2922 | Submission Open

Keywords: quality of life; chronic diseases; patient-reported outcome measures; patient-reported experience measures; supportive interventions; multidisciplinary and holistic approach; symptom control; healthcare accessibility; burden of care prevention; digital health tools; palliative care

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advancements in Urological Diagnostics: Emerging Technologies and Innovative Approaches

edited by

José Enrique Robles-García

submission deadline 31 May 2027 | 4 articles | Viewed by 2447 | Submission Open

Keywords: urological diseases; diagnostic imaging; biomarkers; molecular diagnostics; prostate cancer diagnosis; renal disease diagnosis; artificial intelligence in urology; noninvasive diagnostic techniques

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Photon-Counting CT in Vascular Imaging: Redefining Precision in Vascular Diagnosis

edited by Yousef Shahin

submission deadline 31 May 2027 | 1 articles | Viewed by 1389 | Submission Open

Keywords: photon-counting CT; vascular imaging; coronary artery disease; arteriovenous malformations; peripheral artery disease; artificial intelligence

(This special issue belongs to the Section Medical Imaging and Theranostics)

Arthroscopy Techniques in Diagnosis and Treatment 2026

edited by Maristella Francesca Saccomanno and

Andrea De Fazio

submission deadline 31 May 2027 | 1 articles | Viewed by 1344 | Submission Open

Keywords: arthroscopy; arthroscopy techniques; sports medicine; diagnosis; biological therapies; PROMS

(This special issue belongs to the Section Biomedical Optics)

Diagnosis and Management in Urologic Oncology

edited by Chun-Te Wu, Hao-Lun Luo and

I-Hung Shao

submission deadline 31 May 2027 | Viewed by 1322 | Submission Open

Keywords: urological oncology; prostate cancer; bladder cancer; renal cell carcinoma; molecular diagnostics; artificial intelligence in urology; multiparametric MRI; liquid biopsy; precision medicine; robotic-assisted surgery

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Artificial Intelligence in Biomedical Imaging and Signal Processing—2nd Edition

edited by

Olusola Oluwakemi Abayomi-Alli

Olamilekan Shobayo

and

Modupe Olufunke Odusami

submission deadline 31 May 2027 | Viewed by 1163 | Submission Open

Keywords: artificial intelligence; AI-assisted detection; explainable AI; augmentation

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Innovations in HIV Diagnostics and Monitoring

edited by Nuno Taveira

submission deadline 31 May 2027 | 1 articles | Viewed by 1154 | Submission Open

Keywords: HIV disease; HIV diagnostics; HIV testing; HIV monitoring; point-of-care testing; next-generation sequencing; biomarkers

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Pediatric Gastrointestinal Pathology—2nd Edition

edited by Juan Putra

submission deadline 31 May 2027 | 1 articles | Viewed by 917 | Submission Open

Keywords: inflammatory bowel disease; Crohn’s disease; celiac disease; ulcerative colitis; vascular anomalies; eosinophilic esophagitis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Multimodal Imaging in Clinical Diagnostics: Advances and Perspectives

edited by

Alfonso Reginelli

and Vittorio Patanè

submission deadline 31 May 2027 | 2 articles | Viewed by 733 | Submission Open

Keywords: multimodal imaging; clinical diagnostics; medical imaging; hybrid imaging; radiomics; artificial intelligence; imaging biomarkers; precision medicine; diagnostic accuracy; image fusion

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Diagnostic Testing for Esophageal Diseases

edited by

Micheal Tadros

submission deadline 31 May 2027 | 1 articles | Viewed by 663 | Submission Open

Keywords: esophageal diseases; endoscopy; diagnostic tools; diagnostic testing; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis of Valvular Heart Disease and Myocardial Function, Second Edition

edited by

Vasileios Kamperidis

submission deadline 31 May 2027 | Viewed by 468 | Submission Open

Keywords: echocardiography; speckle tracking; 3D echo; cardiac MRI; cardiac perfusion imaging; aortic stenosis or regurgitation; mitral stenosis or regurgitation; tricuspid stenosis or regurgitation; pulmonary stenosis or regurgitation; transcatheter valvular treatment; surgical valvular treatment

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Management of Neuroendocrine Tumors—2nd Edition

edited by Federica Alessandra Cavalcoli

submission deadline 31 May 2027 | Viewed by 337 | Submission Open

Keywords: neuroendocrine neoplasm; pancreatic neuroendocrine neoplasm; gastric neuroendocrine neoplasm; small-bowel neuroendocrine neoplasm; appendicular neuroendocrine neoplasm; lung neuroendocrine neoplasm; functional imaging; cross-sectional imaging; endoscopic ultrasound

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advancements in Artificial Intelligence for Dentomaxillofacial Radiology—3rd Edition

edited by

Andre Luiz Ferreira Costa

Kaan Orhan

and

Sérgio Lúcio Pereira de Castro Lopes

submission deadline 31 May 2027 | Viewed by 325 | Submission Open

Keywords: artificial intelligence; deep learning; dentomaxillofacial radiology; dentistry; diagnosis

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Beyond ctDNA: New Approaches in Oncology Diagnostics for Earlier Detection of Cancer

edited by Kevin M. Elias and Abigail S. McElhinny

submission deadline 31 May 2027 | Viewed by 319 | Submission Open

Keywords: early detection; multi-omics; liquid biopsy; solid tumors; screening; surveillance

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Hepatobiliary and Pancreatic Diseases: Diagnosis and Management Advances

edited by

Mariano Eduardo Giménez

submission deadline 31 May 2027 | Viewed by 299 | Submission Open

Keywords: hepatobiliary surgery; pancreatic surgery; artificial intelligence; computer-assisted surgery; image-guided surgery; robotic surgery; precision surgery; intraoperative imaging

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Nuclear Medicine and Molecular Imaging for Diagnosis and Prognosis

edited by

Luca Camoni

submission deadline 31 May 2027 | Viewed by 118 | Submission Open

Keywords: nuclear medicine; molecular imaging; PET/CT; SPECT/CT; PET/MRI; theranostics; quantitative imaging; radiomics and artificial intelligence; patient-centred imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Clinical Diagnosis and Prognosis of Hepatobiliary and Pancreatic Diseases

edited by

Ioannis Katsaros

and Michail Vailas

submission deadline 31 May 2027 | Viewed by 82 | Submission Open

Keywords: hepato-pancreato-biliary diseases; pancreatic cancer; hepatocellular carcinoma; cholangiocarcinoma; diagnosis; prognosis; biomarkers; liquid biopsy; medical imaging; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Precision Diagnostic Strategies for Wound Healing

edited by Thomas E. Serena

submission deadline 31 May 2027 | Viewed by 41 | Submission Open

Keywords: chronic wounds; diagnostics; diabetic foot ulcers; venous leg ulcers; pressure ulcers; surgical site infection; personalized medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

New Insights into the Diagnosis of Gynecological Diseases

edited by

Dah Ching Ding

submission deadline 30 Jun 2027 | 5 articles | Viewed by 44540 | Submission Open

Keywords: gynecological diseases; precision medicine; molecular diagnostics; artificial intelligence; biomarkers; next-generation sequencing; imaging technologies; big data

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Prognosis of Gynecological and Obstetric Diseases

edited by

Giuseppe Gullo

and Valentina Billone

submission deadline 30 Jun 2027 | 13 articles | Viewed by 25612 | Submission Open

Keywords: diagnosis; prognosis; gynecological and obstetric diseases; markers; screening

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Echocardiography Applications in Cardiovascular Diseases

edited by

Corina Maria Vasile

submission deadline 30 Jun 2027 | 5 articles | Viewed by 11156 | Submission Open

Keywords: echocardiography; congenital heart disease; imaging techniques; artificial intelligence; automatization

(This special issue belongs to the Section Medical Imaging and Theranostics)

Abdominal Diseases: Diagnosis, Treatment and Management—2nd Edition

edited by

Bogdan Socea

submission deadline 30 Jun 2027 | 12 articles | Viewed by 9157 | Submission Open

Keywords: abdominal diseases; abdominal surgery; diagnosis; image-guided surgery/treatment; minimally invasive techniques; laparoscopy

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advanced Diagnostics in Head and Neck Oncology

edited by Xindong Fan, Siyi Li, Longwei Hu and

Yuchen Shen

submission deadline 30 Jun 2027 | 8 articles | Viewed by 5963 | Submission Open

Keywords: head and neck; tumor; surgical diagnosis; non-invasive diagnostic method; diagnostic biomarkers; intraoperative imaging; pathology; minimally invasive biopsy; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Novel Diagnostic Approaches in Cardiovascular and Metabolic Disorders: From Pathophysiology to Clinical Practice

edited by

Iris Bararu-Bojan

and

Manuela Ciocoiu

submission deadline 30 Jun 2027 | 3 articles | Viewed by 5362 | Submission Open

Keywords: biomarkers; cardiovascular diseases; metabolic disorders; diagnostic imaging; precision medicine; pathophysiology; early diagnosis; risk stratification; omics technologies; clinical application

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Management of Colorectal Diseases, 2nd Edition

edited by

Filippo Carannante

and

Guglielmo Niccolò Piozzi

submission deadline 30 Jun 2027 | 5 articles | Viewed by 4706 | Submission Open

Keywords: colorectal diseases; markers; diagnosis; prognosis; screening

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Cardiovascular and Vascular Imaging

edited by

Alfredo Mauriello

submission deadline 30 Jun 2027 | 3 articles | Viewed by 3368 | Submission Open

Keywords: vascular disease; cardiovascular disease; POCUS; limb disease; vascular imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Optimization of Clinical Imaging: From Diagnosis to Prognosis, 2nd Edition

edited by

Georg Böning

submission deadline 30 Jun 2027 | 3 articles | Viewed by 3206 | Submission Open

Keywords: clinical imaging; medical image analysis; imaging management; computed tomography (CT); magnetic resonance imaging (MRI)

(This special issue belongs to the Section Medical Imaging and Theranostics)

Cardiovascular Diseases: Innovations in Diagnosis and Management

edited by Hisao Hara

submission deadline 30 Jun 2027 | 1 articles | Viewed by 2921 | Submission Open

Keywords: myocardial infarction; biomarker; prognosis; coronary risk; residual risk; prognosis prediction

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Traumatic Brain Injury and Associated Neurological and Neuropsychiatric Disorders: Diagnosis/Prognosis and Therapeutics

edited by

Theodosis Kalamatianos

submission deadline 30 Jun 2027 | 4 articles | Viewed by 2893 | Submission Open

Keywords: traumatic brain injury; neurological and neuropsychiatric disorders; clinical impact and innovation; diagnostic; prognosis; markers; imaging

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Musculoskeletal Imaging in Clinical Practice: From Qualitative Diagnosis to Quantitative Analysis

edited by

Seul Ki Lee

submission deadline 30 Jun 2027 | 5 articles | Viewed by 2474 | Submission Open

Keywords: musculoskeletal imaging; qualitative diagnosis; quantitative imaging; imaging biomarkers; MRI; CT; plain radiograph; ultrasound

(This special issue belongs to the Section Medical Imaging and Theranostics)

Beyond the Image: Cardiac Imaging at the Service of the Patient

edited by

George Koulaouzidis

submission deadline 30 Jun 2027 | 2 articles | Viewed by 2175 | Submission Open

Keywords: cardiac imaging; multimodality; patient outcomes; artificial intelligence; compassion in medicine; quantitative imaging; image-guided therapy; translational cardiology

(This special issue belongs to the Section Medical Imaging and Theranostics)

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