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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in the Diagnosis and Management of Neuropsychiatric Disorders—2nd Edition

edited by

Jesús Ramírez-Bermúdez

submission deadline 31 Dec 2025 | 3 articles | Viewed by 7979 | Submission Open

Keywords: neuropsychiatric disorders; autism; mania; depression; imaging; diagnosis; prognosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Genetic and Genomic Biomarkers in Cancer Diagnosis, Prognosis, and Treatment Prediction

edited by

Jianli Dong

submission deadline 31 Dec 2025 | 7 articles | Viewed by 7341 | Submission Open

Keywords: cancer genetics and genomics; diagnostic tests; prognostic tests; predictive tests; nucleic acid; companion diagnostics; targeted therapy

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Artificial Intelligence in Dermatology

edited by Choon Chiat Oh

submission deadline 31 Dec 2025 | 4 articles | Viewed by 6832 | Submission Open

Keywords: dermatology; artificial intelligence; deep learning; skin cancers; diagnostic imaging

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Ultrasound Diagnosis and Guided Intervention of Musculoskeletal/Neuromuscular Pathology, Second Edition

edited by

Ke-Vin Chang

submission deadline 31 Dec 2025 | 3 articles | Viewed by 6334 | Submission Open

Keywords: diagnosis; ultrasound; pain; muscle; tendon; nerve; rehabiltation

(This special issue belongs to the Section Medical Imaging and Theranostics)

Liquid Biopsy: Cancer Diagnostic Biomarkers of the Future

edited by

Dario Marchetti

submission deadline 31 Dec 2025 | 4 articles | Viewed by 6214 | Submission Open

Keywords: liquid biopsy; circulating tumor cells (CTCs); ctDNA testing; exosomes; blood analytes

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Echocardiography

edited by Grazia Canciello

submission deadline 31 Dec 2025 | 2 articles | Viewed by 6036 | Submission Open

Keywords: echocardiography; cardiovascular imaging; three-dimensional echocardiography; strain imaging; TrueVue imaging; cardiac function assessment; clinical applications; non-invasive cardiology; artificial intelligence

(This special issue belongs to the Section Medical Imaging and Theranostics)

Pathology and Diagnosis of Gynecologic Diseases, 3rd Edition

edited by

Cinzia Giacometti

and Mariateresa Mirandola

submission deadline 31 Dec 2025 | 4 articles | Viewed by 5983 | Submission Open

Keywords: gynecologic pathology; breast pathology; placental pathology; diagnostic pitfalls; differential diagnosis; molecular biology; immunohistochemistry; in situ hybridization

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnostic Techniques in Obstetrics and Gynecology: Current Practices and Future Directions

edited by Giuseppina Porcaro

submission deadline 31 Dec 2025 | 4 articles | Viewed by 5533 | Submission Open

Keywords: diagnosis; prognosis; obstetrics and gynecology markers; clinical practice and patient care

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in the Diagnosis and Management of Bone Diseases in 2025

edited by Hans-Christof Schober

submission deadline 31 Dec 2025 | 3 articles | Viewed by 5335 | Submission Open

Keywords: osteoporosis; diagnostic; morphology; forces; muscle strength; therapy

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Recent Advances in Sepsis

edited by

Zoran Todorovic

submission deadline 31 Dec 2025 | 3 articles | Viewed by 5262 | Submission Open

Keywords: sepsis; biomarkers; diagnosis; personalized medicine

(This special issue belongs to the Section Clinical Laboratory Medicine)

Advances in the Diagnosis of Infectious Diseases and Microorganisms: 2nd Edition

edited by

Philippe Colson

submission deadline 31 Dec 2025 | 5 articles | Viewed by 5216 | Submission Open

Keywords: clinical microbiology; antimicrobial resistance; diagnostic microbiology; molecular microbiology; HIV; infectious diseases

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Pathology and Diagnosis of Head and Neck Diseases

edited by

Eliano Cascardi

submission deadline 31 Dec 2025 | 4 articles | Viewed by 5012 | Submission Open

Keywords: head and neck disease; histopathology; oral tumors; cancer; biomarkers; digital pathology; AI applications; personalized medicine

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Lung Cancer: Screening, Diagnosis and Management: 2nd Edition

edited by

Fu-Zong Wu

submission deadline 31 Dec 2025 | 3 articles | Viewed by 4947 | Submission Open

Keywords: lung cancer; LDCT; overdiagnosis; artificial intelligence; deep learning; prognosis; radiomics; texture analysis; thoracic surgery

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Management of Musculoskeletal Disorders

edited by

Yuichi Yoshii

and

Takeshi Ogawa

submission deadline 31 Dec 2025 | 3 articles | Viewed by 4632 | Submission Open

Keywords: musculoskeletal diseases; MRI; shoulder and elbow; Bone Necrosis; Wrist Arthroscopy

(This special issue belongs to the Section Medical Imaging and Theranostics)

Clinical Diagnosis and Management in Emergency and Hospital Medicine

edited by

Nin-Chieh Hsu

submission deadline 31 Dec 2025 | 4 articles | Viewed by 4525 | Submission Open

Keywords: diagnosis; treatment; management; hospital medicine; emergency medicine; point-of-care ultrasound; decision making; transitional care; palliative care; quality improvement

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Recent Advances in Epidemiological Diagnostics: Detecting and Controlling Infectious Diseases

edited by

Sri Banerjee

and W. Sumner Davis

submission deadline 31 Dec 2025 | 5 articles | Viewed by 4260 | Submission Open

Keywords: epidemiological diagnostics; disease control; clinical practice and patient care; public health; infectious diseases

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Advances in Cardiovascular Diseases: Diagnosis and Management

edited by Hezzy Shmueli

submission deadline 31 Dec 2025 | 4 articles | Viewed by 4260 | Submission Open

Keywords: real-time imaging; cardiovascular disease; cardiovascular imaging; echocardiography; cardiac CT; cardiac MRI; cardiac nuclear scan; acute cardiac care; artificial intelligence; cardiomyopathy

(This special issue belongs to the Section Medical Imaging and Theranostics)

Pathology and Diagnosis of Neurological Disorders, 2nd Edition

edited by James Yip

submission deadline 31 Dec 2025 | 2 articles | Viewed by 4237 | Submission Open

Keywords: stroke; CNS tumors; neurodegenerative diseases; traumatic brain injury

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Eosinophilic Gastrointestinal Disorders: Advances in Diagnosis and Management

edited by

Amir Mari

and

Edoardo V. Savarino

submission deadline 31 Dec 2025 | 1 articles | Viewed by 4180 | Submission Open

Keywords: eosinophilic esophagitis; diagnosis; treatment; histology; epidemiology; risk factors; endoscopy; high resolution manometry; dietary therapy

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Dental Diagnostics

edited by

Dirk Ziebolz

and Margherita Fontana

submission deadline 31 Dec 2025 | 3 articles | Viewed by 4144 | Submission Open

Keywords: diagnosis; diagnostic imaging; artificial intelligence; caries; periodontitis; stomatognathic diseases

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Metabolic Diseases: Diagnosis, Management, and Pathogenesis

edited by Dee Pei

submission deadline 31 Dec 2025 | 4 articles | Viewed by 4104 | Submission Open

Keywords: metabolic disease; obesity; aging; machine learning; pathophysiology; prevalence; ethnic differences

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Clinical Impacts and Challenges in Capsule Endoscopy

edited by

Anastasios Koulaouzidis

submission deadline 31 Dec 2025 | 3 articles | Viewed by 3882 | Submission Open

Keywords: capsule endoscopy; diagnostic endoscopy; small bowel evaluation; non-invasive exploration

(This special issue belongs to the Section Biomedical Optics)

New Technologies and Tools Used for Risk Assessment of Diseases

edited by

Chih-Wei Huang

submission deadline 31 Dec 2025 | 3 articles | Viewed by 3688 | Submission Open

Keywords: digital health; AI in healthcare; machine learning; disease risk prediction; medical imaging; wearable technology; big data analytics; telemedicine; personalized medicine; explainable AI

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Alzheimer's Disease: Diagnosis, Pathology and Management

edited by

Liam L. Chen

submission deadline 31 Dec 2025 | 2 articles | Viewed by 3588 | Submission Open

Keywords: Alzheimer's disease; neuropathology; PET; MRI; CT; dementia; neurodegeneration; immunotherapy; treatment strategy; disease management

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Ultrasound Diagnosis in Maternal Fetal Medicine Practice

edited by

Kwok-yin Leung

Ka-Wang Cheung

and Lau Wai-Lam

submission deadline 31 Dec 2025 | 1 articles | Viewed by 3552 | Submission Open

Keywords: obstetric ultrasound; placenta; fetal abnormalities; color doppler

(This special issue belongs to the Section Medical Imaging and Theranostics)

AI in Radiology and Nuclear Medicine: Challenges and Opportunities

edited by Ioannis M. Tsougos

submission deadline 31 Dec 2025 | 3 articles | Viewed by 3480 | Submission Open

Keywords: diagnosis; prognosis; radiology; nuclear medicine; artificial intelligence (AI)

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Images in the Diagnosis and Treatment of Macular Edema

edited by

Gawęcki Maciej

submission deadline 31 Dec 2025 | 2 articles | Viewed by 3223 | Submission Open

Keywords: macular edema; diagnostic imaging; optical coherence tomography (OCT); fluorescein angiography; retinal imaging techniques

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnostics and Therapeutic Explorations in Aging

edited by

Alvita Vilkevičiūtė

submission deadline 31 Dec 2025 | 1 articles | Viewed by 3145 | Submission Open

Keywords: molecular markers; genetics; epigenetics; biochemistry; biomarkers; telomeres; age-related disease; senescence; mitochondrial dysfunction; immunogenetics

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Recent Advances in Hearing and Audiology Science: Diagnosis and Management

edited by

Yu Sun

submission deadline 31 Dec 2025 | 3 articles | Viewed by 3130 | Submission Open

Keywords: hearing loss; genetic deafness; cochlear implants; hair cell regeneration; central auditory processing; vestibular disorders; tinnitus intervention

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

The Applications of Radiomics in Precision Diagnosis

edited by

Sai Kit Lam

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2981 | Submission Open

Keywords: artificial intelligence in precision diagnosis; disease classification; early diagnosis; imaging biomarkers; radiomics

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Diagnosis and Management of Immunological, Allergic and Inflammatory Disorders

edited by

Zenon Brzoza

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2975 | Submission Open

Keywords: diagnostics; treatment; allergic diseases; autoimmune; immunodeficiency and autoinflammatory syndromes; inflammatory disorders

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

The Clinical Diagnosis, Prognosis, and Management of Gastrointestinal Disease

edited by

Adrian Saftoiu

Bogdan Silviu Ungureanu

and

Irina M. Cazacu

submission deadline 31 Dec 2025 | 1 articles | Viewed by 2843 | Submission Open

Keywords: gastrointestinal diseases; colon cancer; appendicitis; clinical outcomes; prognosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Clinical Diagnosis and Management in Urology

edited by

Roberto Falabella

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2780 | Submission Open

Keywords: minimally invasive surgery; early diagnosis; cancer biomarkers; diagnostic technology; surgical challenges; early diagnosis in urological cancers

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Recent Advances of Endoscopic Ultrasound in Diagnostics and Therapeutics

edited by

Antonio Facciorusso

submission deadline 31 Dec 2025 | 1 articles | Viewed by 2661 | Submission Open

Keywords: endoscopic ultrasound (EUS); diagnostic advances; image resolution; tissue sampling; echoendoscopy

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis and Management of Vascular Diseases

edited by Tiffany R. Bellomo and Abhisekh A. Mohapatra

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2632 | Submission Open

Keywords: diagnosis; management; vascular diseases; marker; non-invasive imaging

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Maternal and Fetal Medicine Research: from Diagnostics to Prognosis

edited by

Edward Araujo Júnior

submission deadline 31 Dec 2025 | 1 articles | Viewed by 2459 | Submission Open

Keywords: maternal; fetal; perinatal period; prenatal diagnosis; pregnancy

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Molecular Diagnostics in Cardiovascular Diseases: From Biomarkers to Personalized Medicine

edited by Otilia Țica

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2448 | Submission Open

Keywords: cardiovascular disease; biomarkers; precision medicine; diagnostics; heart failure

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Cardiovascular Diseases: Advances in Diagnosis and Management

edited by

Thien Tan Tri Tai Truyen

submission deadline 31 Dec 2025 | 1 articles | Viewed by 2430 | Submission Open

Keywords: cardiovascular diseases; predictive risk score; mortality; prognosis; artificial intelligence; machine learning; large language models

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

New Trends in Musculoskeletal Imaging

edited by

Ugo Carraro

submission deadline 31 Dec 2025 | 3 articles | Viewed by 2359 | Submission Open

Keywords: genetic and acquired skeletal muscle disorders; mobility functional tests; skeletal muscle imaging; light and electron microscopy; quantitative tissue densitometry by 3D and 2D color CT and MRI; blood and mouth fluid biomarkers; targeted management and follow-up in mobility medicine; functional electrical stimulation of denervated and reinnervating muscles; home full-body in-bed gym exercise; hemi-fasting and other nutritional supplements of mobility medicine in aging; spa; thermal; and balneotherapy

(This special issue belongs to the Section Medical Imaging and Theranostics)

Emergency and Critical Care Medicine: Diagnosis and Management

edited by

Ivan Gornik

submission deadline 31 Dec 2025 | 1 articles | Viewed by 2330 | Submission Open

Keywords: ICU; emergency medicine; trauma and injury; acute illness; accurate diagnosis; imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Recent Advances in Bone and Joint Imaging—3rd Edition

edited by

Yuichi Yoshii

submission deadline 31 Dec 2025 | 3 articles | Viewed by 2325 | Submission Open

Keywords: musculoskeletal imaging; machine learning; bone imaging; computed tomography; ultrasound imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Imaging in Oral Surgery: Advancing the Frontiers of Precision Diagnosis and Treatment Planning

edited by Anusha Vaddi

submission deadline 31 Dec 2025 | 1 articles | Viewed by 2262 | Submission Open

Keywords: oral surgery; digital radiography; treatment planning; diagnosis; augmented reality; 3D printing

(This special issue belongs to the Section Medical Imaging and Theranostics)

Recent Advances in Heart Failure: Clinical Diagnosis, Treatment, and Prognosis

edited by

Massimo Mapelli

and Irene Mattavelli

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2000 | Submission Open

Keywords: heart failure; clinical diagnosis; treatment advances; precision medicine; exercise evaluation; CPET

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Neurological Disorders: Diagnosis and Management

edited by

Lung Chan

submission deadline 31 Dec 2025 | 3 articles | Viewed by 1956 | Submission Open

Keywords: stroke diagnosis; treatment outcome prediction; neuroimaging; machine learning; biomarkers; personalized medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Pathological Speech Classification and Processing for Advanced Medical Diagnosis

edited by

Juan Rafael Orozco-Arroyave

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1877 | Submission Open

Keywords: pathological speech; medical diagnosis; classification and processing; Parkinson's disease; hypokinetic dysarthria; dysarthria; aphasia; voice disorders; dysphonia; AI

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Prognostic Factors for Pediatric Tumors, 2nd Edition

edited by

Maria Kourti

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1877 | Submission Open

Keywords: childhood cancer; prognostic factors; acute leukemia; solid tumors

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnostic Imaging of Brain Disease, Second Edition

edited by

Rosalinda Calandrelli

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1741 | Submission Open

Keywords: adenomas; craniopharyngiomas; skull base lesions; infections; cystic lesions; vascular lesions; MRI; CT; radiomics

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Sleep and Respiratory Medicine

edited by Cheng-Yu Tsai

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1718 | Submission Open

Keywords: sleep and respiratory disorders; chest medicine; AI in healthcare; digital technology; precision diagnostics

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Multimodal Imaging: Enhancing Precision Medicine Across Diverse Clinical Pathways

edited by

Mariano Scaglione

and Salvatore Masala

submission deadline 31 Dec 2025 | 2 articles | Viewed by 1643 | Submission Open

Keywords: CT; XR; CT US; MRI; functional MRI; PET; SPECT

(This special issue belongs to the Section Medical Imaging and Theranostics)

Progress in Chronic Pain: Bridging Basic and Clinical Research

edited by

Helder Cardoso-Cruz

and

Clara Monteiro

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1526 | Submission Open

Keywords: chronic pain; pain prevention; new biomarkers in chronic pain; personalized treatment approaches; sensory and cognitive dimensions; neuropathic pain; inflammatory pain

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

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