Natural Products as Potential Sources of Antidiabetic Compounds

Dear Colleagues,

Natural products (NPs) have played a crucial role in the drug discovery process in order to treat numerous diseases. Plants, fungi, bacteria, and other natural sources produce NPs with intriguing chemical diversity illustrating interesting biological effects for numerous disease treatments. Notably, NP-based drugs are usually considered to be safer, cheaper, and easily available. Diabetes is one of the chronic disorders associated with high mortality risk. Unfortunately, the currently used drugs have been identified with one or more adverse effects. This indicates that there is still an urgent need for the development of novel antidiabetic drugs with a unique mechanism of action.

The focus of this Special Issue is on natural products (NPs)-based antidiabetic molecules and NPs-based synthetic antidiabetic compounds. Furthermore, this Issue will also place emphasis on the relationship between the chemical structure and the biological activity of the molecules at the molecular level together with applying bioinformatics in diabetes. Moreover, this Special Issue also welcomes articles on the antidiabetic effects of α-glucosidase, amylase, protein tyrosine phosphatase 1B (PTP1B), and dipeptidyl peptidase (DPP)-4 inhibition at the molecular level (kinetic studies). This Special Issue will also focus on the development of new therapeutic agents for diabetes treatment, employing the newest techniques of pharmacology, biotechnology, and genetic engineering. This Issue welcomes original articles, communications, and reviews dealing with diabetes treatment.

Prof. Dr. Hidayat Hussain
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Current Issues in Molecular Biology is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.