Special Issues

Cells publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Mitochondrial Dynamics and Remodelling
edited by Edmund Carvalho
submission deadline 30 Jun 2026 | Viewed by 111 | Submission Open
Keywords: mitochondrial dynamics; fission; fusion; mitophagy; cristae remodeling; bioenergetics; ER– mitochondria contacts; immune reprogramming; signaling pathways; therapeutic targeting
Molecular Basis of Gynecological Disorders and Associated Infertility submission deadline 30 Jun 2026 | Viewed by 107 | Submission Open
Keywords: gynecological disorders; endometriosis; polycystic ovary syndrome (PCOS); cervical cancer; ovarian cancer; uterine and vaginal pathologies
(This special issue belongs to the Section Cellular Pathology)
Translating Extracellular Vesicle Science submission deadline 30 Jun 2026 | Viewed by 107 | Submission Open
Keywords: extracellular vesicles (EVs); EV isolation; EV purification; EV characterization; EV images; EV tracking; EV-based diagnostics; EV-based monitoring; EV therapeutics; blood biomarkers; translational medicine; exosomes; cell signaling
Bone and Tooth Biology: Development and Regeneration
edited by Xiaofang Wang
submission deadline 30 Jun 2026 | Viewed by 104 | Submission Open
Keywords: bone; tooth; osteogenesis; odontogenesis; enamel; dentin; cementum; amelogenesis; dentinogenesis; regeneration; stem cells  
Nuclear Organization and Nucleocytoplasmic Transport in Neuronal Development and Disease: Mechanisms and Therapeutic Opportunities submission deadline 30 Jun 2026 | Viewed by 96 | Submission Open
Keywords: nuclear organization; nucleocytoplasmic transport; neuronal development; neurodegeneration; nuclear pore complex (NPC); nuclear lamina; RNA trafficking; chromatin regulation; therapeutic targeting; neurodevelopmental disorders
(This special issue belongs to the Section Cellular Neuroscience)
Tau Pathobiology and Excitotoxicity in Neurodegeneration and Epilepsy
edited by Janet Van Eersel
submission deadline 30 Jun 2026 | Viewed by 83 | Submission Open
Keywords: tau; excitotoxicity; dementia; epilepsy; seizures; hyperexcitation
Neural Stem Cells and Progenitors: Mechanisms of Neurogenesis and Regenerative Potential
edited by Lidia De Filippis and Maurizio Gelati
submission deadline 30 Jun 2026 | Viewed by 73 | Submission Open
Keywords: neural stem cells; cancer stem cells; neuroregeneration; neurodegenerative diseases; CNS; neurorepair; neurogenesis; neuroinflammation
The Immunology of Allergy and Asthma submission deadline 30 Jun 2026 | Viewed by 69 | Submission Open
Keywords: type 2 immunity; rhinitis; food allergy; anaphylaxis; drug allergy; dermatitis; eczema; airway inflammation; IgE response; tissue remodelling; disease remission
Advances in Cell-Based Studies and Therapeutic Approaches for Tissue Regeneration—Second Edition submission deadline 30 Jun 2026 | Viewed by 67 | Submission Open
Keywords: soft/hard tissue regeneration; therapeutic approaches; cell culture studies; inflammation-based diseases; degenerative diseases
(This special issue belongs to the Section Tissues and Organs)
Role of Macrophages in Tissue Repair
edited by
submission deadline 30 Jun 2026 | Viewed by 64 | Submission Open
Keywords: macrophages; inflammation; tissue repair; phagocytosis
(This special issue belongs to the Section Tissues and Organs)
Multifaceted Nature of Immune Responses to Viral Infection
edited by Homayon Ghiasi and Susmit Suvas
submission deadline 30 Jun 2026 | Viewed by 62 | Submission Open
Keywords: viral infection; innate and adaptive immunity; protection; RNA and DNA viruses; autoimmunity; immune escape
Synaptic Condensates: Liquid–Liquid Phase Separation of Pre- and Postsynaptic Scaffold Proteins in Synapse Development and Memory Formation
edited by Norbert Bencsik and
submission deadline 30 Jun 2026 | Viewed by 57 | Submission Open
Keywords: liquid– liquid phase separation (LLPS); synaptic plasticity; synapse development; postsynaptic density (PSD); scaffold proteins; synaptic dysfunction; neural circuits
(This special issue belongs to the Section Cellular Neuroscience)
Inflammation in Target Organs—Second Edition
edited by
submission deadline 30 Jun 2026 | Viewed by 52 | Submission Open
Keywords: inflammation; fibrosis; cardio-renal; vascular; liver; brain
(This special issue belongs to the Section Cellular Immunology)
Cell Metabolism in Endocrine Diseases
edited by Ranjodh Gill
submission deadline 30 Jun 2026 | Viewed by 42 | Submission Open
Keywords: endocrine system; hormones; metabolism; cellular pathways; homeostasis; diabetes mellitus; insulin resistance; thyroid disorders; hypothyroidism; hyperthyroidism; cortisol; Cushing's syndrome
(This special issue belongs to the Section Cellular Metabolism)
The Study of Skeletal Diseases
edited by Weiguang Wang
submission deadline 30 Jun 2026 | Viewed by 38 | Submission Open
Keywords: skeletal diseases; bone; cartilage; synovium; tendon; ligament; spine; craniofacial skeleton; immune– skeletal interaction; vascular and neural networks; stem and progenitor cells; artificial intelligence (AI); single-cell and spatial genomics; imaging and bioengineering; regenerative medicine
(This special issue belongs to the Section Cellular Pathology)
Advances in the Biology and Treatment of T-Cell Lymphoma submission deadline 30 Jun 2026 | Viewed by 30 | Submission Open
Keywords: T-cell lymphoma; cancer biology; oncogenic signaling; cellular mechanisms; cell– cell interactions; targeted therapy
(This special issue belongs to the Section Cellular Immunology)
Epithelial-Immune Cell Interactions in Gut Homeostasis and Inflammation
edited by Neeraj Kapur
submission deadline 30 Jun 2026 | Viewed by 29 | Submission Open
Keywords: gut homeostasis; epithelial barrier; immune cell crosstalk; barrier dysfunction; intestinal inflammation; microbiota; dysbiosis
(This special issue belongs to the Section Cellular Immunology)
Cellular Reprogramming and Epigenetic Control in Tissue Regeneration
edited by Sanjeeb Kumar Sahu
submission deadline 30 Jun 2026 | Viewed by 29 | Submission Open
Keywords: cellular reprogramming; epigenetic regulation; tissue regeneration; epigenetic rejuvenation; cellular plasticity; stem cell biology; regenerative medicine; DNA methylation
(This special issue belongs to the Section Tissues and Organs)
Melatonin in Neuroprotection: Mechanisms, Mitochondria, and Therapeutic Potential submission deadline 30 Jun 2026 | Viewed by 24 | Submission Open
Keywords: neurodegenerative disorders; melatonin; neuroprotection; mitochondria; oxidative stress; neuroinflammation; mitochondrial dynamics; therapeutic potential
(This special issue belongs to the Section Mitochondria)
Novel Insights into Myeloid Leukemias submission deadline 30 Jun 2026 | Viewed by 21 | Submission Open
Keywords: leukemogenesis; bone marrow microenvironment; leukemia stem cells; immune evasion; hematopoiesis and myeloid differentiation; targeted therapy
(This special issue belongs to the Section Cellular Pathology)
Immunometabolic Mechanisms in Aging and Chronic Inflammatory Diseases: From Senescence to Autoimmunity submission deadline 30 Jun 2026 | Viewed by 20 | Submission Open
Keywords: immuno-metabolic; immune response; senescence; inflammation; immune cells; cell differentiation; cell maturation; autoimmunity; cancer
(This special issue belongs to the Section Cellular Immunology)
Innovations in mRNA Delivery Vectors submission deadline 30 Jun 2026 | Viewed by 14 | Submission Open
Keywords: mRNA delivery systems; lipid nanoparticles (LNPs); non-viral vectors; targeted RNA delivery; extracellular vesicles
Targeting Retinal Neurogliovascular Injury: Mechanisms and Therapeutic Strategies submission deadline 30 Jun 2026 | Viewed by 13 | Submission Open
Keywords: retinal neurogliovascular injury; retinal neurogliovascular disease; mechanisms; therapeutic strategies
(This special issue belongs to the Section Cellular Pathology)
Plant Stress Biology Under Biotic and Abiotic Environment submission deadline 30 Jun 2026 | Viewed by 10 | Submission Open
Keywords: abiotic stress; microscopy; molecular biology; photosynthesis; phytohormnes; plant-pathogen interaction; plant physiology; plant biology; transcriptomics
(This special issue belongs to the Section Plant, Algae and Fungi Cell Biology)
Sex Hormone-Driven Cancers: Molecular Pathogenesis, Metabolic Reprogramming and Therapeutic Frontiers submission deadline 30 Jun 2026 | Viewed by 7 | Submission Open
Keywords: sex hormones; androgen; estrogen; progesterone; breast cancer; ovarian cancer; endometrial cancer; prostate cancer; metabolic reprogramming; tumor microenvironment; drug resistance; cancer metabolism; metastasis
(This special issue belongs to the Section Cellular Pathology)
Mitochondrial Dynamics in Cancer Metabolism: Mechanisms and Functional Consequences
edited by Che-Chia Hsu
submission deadline 30 Jun 2026 | Viewed by 1 | Submission Open
Keywords: mitochondrial fission; mitochondrial fusion; mitophagy; mitochondrial transport; mitochondrial transfer; mitochondrial diseases
(This special issue belongs to the Section Mitochondria)
Innate-Like T Cells: The Variegated Roles of Semi-Invariant TCRs in Health and Disease
edited by and Akshat Sharma
submission deadline 5 Jul 2026 | Viewed by 2360 | Submission Open
Keywords: innate-like T cells; cancer; autoimmunity; cytokines; immune mechanisms
(This special issue belongs to the Section Cellular Pathology)
Biochemical Interaction and Supramolecular Complexes of Receptors in Cell Membranes submission deadline 8 Jul 2026 | 1 articles | Viewed by 1508 | Submission Open
Keywords: membrane receptors; molecular complex; membrane microdomains
Experimental Systems to Model Aging Processes
edited by , and Ralf Dahm
submission deadline 10 Jul 2026 | 4 articles | Viewed by 9742 | Submission Open
Keywords: aging; ageing; age-related; longevity; model; animal; signalling pathway; mechanism; in vitro; in vivo; cell culture; marker
(This special issue belongs to the Section Cellular Aging)
Advances in Human Pluripotent Stem Cells submission deadline 10 Jul 2026 | 3 articles | Viewed by 3611 | Submission Open
Keywords: human pluripotent stem cells; embryonic stem cells; induced pluripotent stem cells  
(This special issue belongs to the Section Stem Cells)
Ripening and Degradation Mechanisms of Neutrophil Extracellular Traps
edited by and Maximilian Dölling
submission deadline 10 Jul 2026 | Viewed by 562 | Submission Open
Keywords: neutrophil extracellular traps; degradation of NETs; ripening of NETs
(This special issue belongs to the Section Cellular Immunology)
The Role of Mitochondria in Health, Disease, and Ageing submission deadline 10 Jul 2026 | Viewed by 35 | Submission Open
Keywords: mitochondrial dysfunction; metabolism; mitochondrial genetics; aging and senescence; bioenergetics; mitophagy; neurodegeneration; cardiomyopathy; metabolic syndrome; ocular diseases
(This special issue belongs to the Section Mitochondria)
Hypoxia and the Immune Landscape in Infection and Cancer
edited by Bernard Burke
submission deadline 10 Jul 2026 | Viewed by 24 | Submission Open
Keywords: hypoxia; tumor; infection; HIFs; immune checkpoint proteins; immune evasion; metabolic dysregulation; leukocyte recruitment; effector cell function; acidosis
(This special issue belongs to the Section Cellular Immunology)
Cellular Signaling Networks in Development, Homeostasis, and Disease
edited by , and Chia-Yang Liu
submission deadline 10 Jul 2026 | Viewed by 22 | Submission Open
Keywords: cell fate determination; cell migration and survival; cell proliferation and differentiation; development and homeostasis; developmental disorders; disease mechanisms; regenerative medicine; signal transduction; signaling crosstalk; spatial transcriptomics
(This special issue belongs to the Section Cell Signaling)
Neuromodulatory Signaling in Brain Disorders: State-of-the-Art Insights
edited by and
submission deadline 15 Jul 2026 | 3 articles | Viewed by 7305 | Submission Open
Keywords: neuromodulatory signaling; neural circuit; synaptic plasticity; neurotransmitter; signal transduction; neurodegenerative diseases; neuroinflammatory disorder; substance use disorder; neurodevelopmental disorder; targeted therapy
(This special issue belongs to the Section Tissues and Organs)
Tumor Stroma Interaction
edited by
submission deadline 15 Jul 2026 | 1 articles | Viewed by 3481 | Submission Open
Keywords: cells; cancer; inflammation; exocytosis; immune system; tumor stroma
Inflammation in the Brain: From Molecular and Cellular Mechanisms to Therapeutic Strategies
edited by Sujatha Kannan and
submission deadline 15 Jul 2026 | 1 articles | Viewed by 1519 | Submission Open
Keywords: neuroinflammation; microglia; astrocytes; immune signaling; neurodegeneration; neuroimmunology; brain injury; therapeutic strategies
Recent Advances in the Understanding of Neuropsychiatric Illnesses
edited by and
submission deadline 15 Jul 2026 | Viewed by 415 | Submission Open
Keywords: neuropsychiatric disorders; neurodegeneration; synaptic plasticity; neuroinflammation; biomarkers; molecular mechanisms; translational neuroscience; intracellular signaling; neuroimaging
(This special issue belongs to the Section Cellular Neuroscience)
Functions of Cilia
edited by
submission deadline 15 Jul 2026 | Viewed by 271 | Submission Open
Keywords: cilia; cilia-derived vesicles; ciliopathies; neuronal cilia; motile cilia; primary cilia; ciliary secretion; peptidergic signaling; ectosomes
Role of Hippo Signaling in Cancer submission deadline 15 Jul 2026 | Viewed by 94 | Submission Open
Keywords: angiogenesis; cancer metabolism; cancer stemness; chemoresistance; endothelial cell plasticity; epithelial-to-mesenchymal transition (EMT); hippo signaling pathway; immunotherapy; mechanotransduction; targeted cancer therapy; TEAD transcription factors; therapeutic resistance; tumor microenvironment; tumorigenesis; YAP/TAZ; new therapeutic modalities to target YAP/TAZ-driven tumors including ferroptosis
(This special issue belongs to the Section Cell Signaling)
MET: Signaling, Regulation, and Biological Roles
edited by Abdulhameed Al-Ghabkari and William W. Lockwood
submission deadline 15 Jul 2026 | Viewed by 82 | Submission Open
Keywords: MET; HGF (hepatocyte growth factor); MET signaling; receptor tyrosine kinase (RTK); cancer; tumor progression; receptor activation; MET-targeted therapy
(This special issue belongs to the Section Cell Signaling)
Second Edition of Advances in Adipose Tissue Biology
edited by
submission deadline 20 Jul 2026 | 2 articles | Viewed by 4688 | Submission Open
Keywords: adipocyte differentiation; progenitors; and stem cells; adipokines; myokines; hepatokines; cytokines; cellular signaling; and molecular crosstalk; white adipose tissue (WAT) and brown adipose tissue (BAT); beige fat and browning of WAT; research techniques and methodologies; diagnostics and therapeutics; genomics; metabolomics; other ‘ omics’ technologies; metabolic syndrome; obesity; insulin resistance; cancer
(This special issue belongs to the Section Tissues and Organs)
Applications of Nanotechnology and Molecular Imaging in Cancer
edited by and Victoria Laney
submission deadline 20 Jul 2026 | Viewed by 11 | Submission Open
Keywords: contrast agents and mechanisms; probes; molecular imaging; longitudinal imaging; tumor microenvironment; nanomaterials; cell signaling; cancer therapy; intracellular pathways; imaging-guided treatment
Novel Molecular Targets for the Treatment of Sleep Disorders
edited by
submission deadline 25 Jul 2026 | Viewed by 312 | Submission Open
Keywords: sleep disorders; molecular targets; glymphatic system; neuroinflammation; circadian rhythms; microbiome; biomarkers; pharmacological therapy; gene therapy; neurodegeneration
Toxicology in Cells: Cellular Mechanisms, Molecular Responses, and Modern Models
edited by Maria Jurczuk and
submission deadline 30 Jul 2026 | Viewed by 92 | Submission Open
Keywords: cellular toxicology; oxidative stress; apoptosis; autophagy; biomarkers; nanotoxicology; organ-on-chip; toxicogenomics; epigenetic regulation; mitochondrial dysfunction
Mitochondria in Cancer Immune Evasion and Immunotherapy
edited by Loredana Moro and
submission deadline 30 Jul 2026 | Viewed by 59 | Submission Open
Keywords: mitochondria; mtDNA; immunity; cancer immune evasion; tumor microenvironment; immune tolerance; lymphocytes; inflammation; immune response
(This special issue belongs to the Section Cellular Immunology)
New Advances in Immunomodulation Using Biomaterials
edited by and Vaishali Inamdar
submission deadline 30 Jul 2026 | Viewed by 21 | Submission Open
Keywords: immunomodulation; biomaterials; cell– material interactions; biocompatibility; immune system
Cellular Mechanisms of Anti-Cancer Therapies
edited by Ilgen Mender and
submission deadline 31 Jul 2026 | 8 articles | Viewed by 17863 | Submission Open
Keywords: anti-cancer therapies; innovative treatment strategies; cellular mechanisms; drug resistance; personalized medicine
(This special issue belongs to the Section Cellular Pathology)
How Can We Optimise Cancer Therapy? Tumour Microenvironment and Immune Evasion Strategies submission deadline 31 Jul 2026 | 6 articles | Viewed by 8870 | Submission Open
Keywords: immunosurveillance; immune evasion in cancer; tumour microenvironment; immune suppression; immunotherapy; immune checkpoints; cancer immunity; drug intervention
(This special issue belongs to the Section Cell Microenvironment)
Advances in the Discovery of Retinal Degeneration submission deadline 31 Jul 2026 | 5 articles | Viewed by 6677 | Submission Open
Keywords: retinal cell biology; photoreceptors; oxidative stress; inflammation; blood– retinal barriers; diabetic retinopathy; clinical eye research; inherited retinal diseases; ocular immunology
(This special issue belongs to the Section Cellular Pathology)
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