New Advances in Immunomodulation Using Biomaterials
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: 30 July 2026 | Viewed by 788
Special Issue Editors
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Special Issue Information
Dear Colleagues,
Immunomodulatory biomaterials and devices have emerged as one of the most powerful frontiers in biomedical science. These biomaterials and devices enable control over immune responses and integrate principles of materials science, immunology, and engineering. The specific function of these platforms can be designed to present biological signals to recruit or reprogram immune cells and create microenvironments that direct tissue repair or enhance therapeutic efficacy. Over the last decade, the field has expanded rapidly from immune-instructive hydrogels and nanoparticle delivery systems to advanced scaffolds and engineered matrices that actively engage immune pathways.
However, fundamental challenges remain in understanding how material properties, such as mechanics, biocompatibility, degradability, surface chemistry, and ligand presentation, shape immune cell behavior and host responses. Deciphering these interactions is key to designing next-generation biomaterials that can achieve selective immunomodulation, minimize adverse reactions, and promote durable therapeutic outcomes.
For this Special Issue on New Advances in Immunomodulation Using Biomaterials, we invite original research articles and reviews that advance our understanding of how biomaterials can be used to modulate immune function across diverse applications such as solid tumor treatment, cardiovascular diseases, tissue repair and regeneration, infectious diseases, etc.
This Special Issue will highlight studies that reveal how biomaterials can be engineered to harness or modulate immunity, with the goal of advancing next-generation therapies that are safer and more effective.
We look forward to receiving your contributions to this exciting and rapidly evolving field.
Prof. Dr. Gundula Schulze-Tanzil
Dr. Vaishali Inamdar
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- immunomodulation
- biomaterials
- cell–material interactions
- biocompatibility
- immune system
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