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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Emerging Therapies for Germ Cell Tumors

edited by

Ratnakar Singh

and Krinio Giannikou

submission deadline 30 Jun 2026 | Viewed by 143 | Submission Open

Keywords: testicular cancer; embryonal carcinoma; germ cell tumors; cisplatin; immunotherapy; epigenetics; microRNA; chemoresistance; animal models; targeted therapy

(This special issue belongs to the Section Cancer Therapy)

Updates on Anti-Cancer Drug Research

edited by

Ana Luísa De Sousa-Coelho

and Mónica Fernandes

submission deadline 30 Jun 2026 | Viewed by 141 | Submission Open

Keywords: anti-cancer drug research; drug resistance; biomarkers; pharmacogenomics; single-cell RNA sequencing; non-coding RNAs; multi-omics data

(This special issue belongs to the Section Cancer Drug Development)

A New Road for Cancer Drug Discovery

edited by

Navnath S. Gavande

and

Yubin Ge

submission deadline 30 Jun 2026 | Viewed by 137 | Submission Open

Keywords: cancer drug discovery; artificial intelligence in drug discovery and development; targeted therapy; precision oncology; targeted protein degrades; small-molecule therapeutics; immuno-oncology; undruggable targets; drug resistance mechanisms; combination therapy

(This special issue belongs to the Section Cancer Drug Development)

Tumor Microenvironment of Thyroid Carcinoma

edited by

Juan Carlos Jaume

submission deadline 30 Jun 2026 | Viewed by 136 | Submission Open

Keywords: thyroid cancer; tumor immune microenvironment (TIME); double-negative T cells (DN T cells); tumor-associated macrophages (TAMs)

(This special issue belongs to the Section Tumor Microenvironment)

Basic and Translational Science in Ocular Oncology

edited by Anthony B. Daniels,

Arun D. Singh

and

Jens Folke Kiilgaard

submission deadline 30 Jun 2026 | Viewed by 131 | Submission Open

Keywords: ocular oncology; eye cancer; tumors; melanoma; retinoblastoma; hemangioma; hemangioblastoma; lymphoma

(This special issue belongs to the Section Cancer Pathophysiology)

Arginine and Cancers: Molecular Mechanisms and Anticancer Therapy

edited by

Maria Francesca Baietti

submission deadline 30 Jun 2026 | Viewed by 130 | Submission Open

Keywords: arginine; cancer; therapy; immunotherapy; metabolism

(This special issue belongs to the Section Cancer Drug Development)

Genomics and Genetics in Brain Cancer Treatment, Diagonals, and Prognosis

edited by

Nan Hu

submission deadline 30 Jun 2026 | Viewed by 125 | Submission Open

Keywords: genomics; genetics; brain tumor; brain cancer; glioblastoma multiform; glioma; cancer diagnosis; cancer prognosis

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Human Carcinogens—New Insights from Occupational Exposure

edited by

Enrico Oddone

and

Roberta Pernetti

submission deadline 30 Jun 2026 | Viewed by 122 | Submission Open

Keywords: occupational carcinogens; chemical exposure; cancer prevention; artificial intelligence (AI); workplace health policy

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Evolving Management of Gastroesophageal Cancers: From Local Therapies to Precision Oncology

edited by

Ilyas Sahin

submission deadline 30 Jun 2026 | Viewed by 119 | Submission Open

Keywords: gastric cancer; esophageal cancer; immunotherapy targeted therapy; radiation therapy; surgical oncology; precision oncology; molecular biomarkers; multimodal treatment

(This special issue belongs to the Section Cancer Therapy)

Redox Balance, Antioxidant Defenses, and Inflammation in Cancer: From Initial Changes to Tumor Progression

edited by Andrej Veljković,

Gordana Kocic

and

Aleksandra Klisic

submission deadline 30 Jun 2026 | Viewed by 118 | Submission Open

Keywords: oxidative stress; inflammation; cancer progression; pre-malignant changes; biomarkers; tumor microenvironment; cell signaling; therapeutic targets

(This special issue belongs to the Section Tumor Microenvironment)

Myeloma and Immunology

edited by

Cristina João

submission deadline 30 Jun 2026 | Viewed by 113 | Submission Open

Keywords: multiple myeloma; tumor immunology; immune microenvironment; immunotherapy; CAR-T cells; immune evasion; immune profiling

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Pharmacokinetics in Cancer Treatment

edited by Jing Li

submission deadline 30 Jun 2026 | Viewed by 113 | Submission Open

Keywords: pharmacokinetics (PK); pharmacodynamics (PD); population PK/PD modeling; PBPK modeling; clinical pharmacology; personalized oncology; cancer treatment; pharmacogenetics; molecular pharmacology

(This special issue belongs to the Section Cancer Drug Development)

Advances in Clinical Treatment of Pancreatic Cancers

edited by

Alberto Brolese

submission deadline 30 Jun 2026 | Viewed by 112 | Submission Open

Keywords: pancreatic cancer; PDAC; neoadjuvant chemotherapy; neuroendocrine tumors; pNET; pancreatic cystic disease; IPMN; pancreatic oligometastases

(This special issue belongs to the Section Clinical Research of Cancer)

Immunotherapy Approaches in Breast Cancer Treatment (2nd Edition)

edited by Yi Huang and

Bing Li

submission deadline 30 Jun 2026 | Viewed by 106 | Submission Open

Keywords: breast cancer progression; immunotherapy; combination therapy; drug discovery; antitumor immunity; tumor immune microenvironment; biomarkers and clinical trials

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Clinical Application of Proton Therapy and Advanced Radiotherapy in Gynecological Cancer

edited by Amy Tien Yee Chang and

Bin Yang

submission deadline 30 Jun 2026 | Viewed by 106 | Submission Open

Keywords: proton therapy; cervical cancer; endometrial cancer; vaginal cancer; MR-guided radiotherapy; MR-guided brachytherapy; stereotactic body radiotherapy

(This special issue belongs to the Section Cancer Therapy)

Research and Treatment of Hepatocellular Carcinoma

edited by Chung Cheung Thomas Yau

submission deadline 30 Jun 2026 | Viewed by 105 | Submission Open

Keywords: hepatobiliary cancer; biomarker; immunotherapy; targeted therapy; combination treatments

(This special issue belongs to the Section Cancer Therapy)

Contemporary Thoracic Cancer Surgery: Technology and Innovation

edited by

Yoshikane Yamauchi

submission deadline 30 Jun 2026 | Viewed by 103 | Submission Open

Keywords: thoracic cancer surgery; robotic-assisted thoracic oncology procedures; video-assisted thoracoscopic surgery for thoracic malignancies; thoracic neoplasms; minimally invasive surgery in cancer treatment; surgical outcomes; lung cancer surgery; surgical innovation in thoracic oncology

(This special issue belongs to the Section Methods and Technologies Development)

Nanocarriers in Cancer Therapy

edited by

Wenyi Gu

submission deadline 30 Jun 2026 | Viewed by 92 | Submission Open

Keywords: nanoparticles; cancer therapy; anticancer drug delivery

(This special issue belongs to the Section Methods and Technologies Development)

Long-Read Sequencing in Cancer (2nd Edition)

edited by

Luca Ermini

and Patrick Driguez

submission deadline 30 Jun 2026 | Viewed by 92 | Submission Open

Keywords: long-read sequencing; cancer genetics; genomics; transcriptomics; methylomics; cancer research

(This special issue belongs to the Section Molecular Cancer Biology)

Prostate Cancer Pathology and Grade

edited by

Stefano Marletta

and

Giuseppe Fanelli

submission deadline 30 Jun 2026 | Viewed by 91 | Submission Open

Keywords: prostate cancer; Gleason grading; molecular pathology; artificial intelligence; digital pathology; multimodal algorithms

(This special issue belongs to the Section Cancer Pathophysiology)

Advances in Targeted Therapies and Pharmacogenomics of Leukemia

edited by

Nicolas Nassar

submission deadline 30 Jun 2026 | Viewed by 86 | Submission Open

Keywords: blood cancer; targeted therapy; immunotherapy; primary and secondary resistance; pharmacogenetics; combination therapy; tumor microenvironment

(This special issue belongs to the Section Molecular Cancer Biology)

CDK4/6 Inhibitors in Cancer: Efficacy, Resistance, and Combination Approaches

edited by

Boshi Wang

submission deadline 30 Jun 2026 | Viewed by 78 | Submission Open

Keywords: CDK4/6 inhibitors; palbociclib; abemaciclib; ribociclib; cancer; senescence; combinatorial therapy; prognosis; molecular mechanisms

(This special issue belongs to the Section Cancer Therapy)

Molecular Mechanisms of Cancer Progression and Metastasis

edited by

Babak Behnam

submission deadline 30 Jun 2026 | Viewed by 73 | Submission Open

Keywords: metastasis; molecular mechanisms; tumor microenvironment (TME); epithelial-to-mesenchymal transition (EMT); cancer stem cell; therapeutic strategies; immune evasion

(This special issue belongs to the Section Cancer Metastasis)

Tumor Heterogeneity in Breast Cancer—the “Omics” Revolution

edited by

Angeliki Magklara

and

Spyros Foutadakis

submission deadline 30 Jun 2026 | Viewed by 70 | Submission Open

Keywords: breast cancer; tumor heterogeneity; tumor microenvironment; transcriptional regulation; single-cell RNA-seq; spatial transcriptomics; genomics; epigenomics; proteomics; metabolomics

(This special issue belongs to the Section Molecular Cancer Biology)

Radiation Therapy for Metastatic Cancer

edited by Johnny Kao

submission deadline 30 Jun 2026 | Viewed by 68 | Submission Open

Keywords: metastasis; radiation therapy; tumor agnostic; oligometastases; survivorship; combined modality therapy

(This special issue belongs to the Section Cancer Therapy)

Symptom Burden in Cancer: Assessment and Management: 2nd Edition

edited by Sam M. Salek,

Esther Natalie Oliva

and Tatyana Ionova

submission deadline 30 Jun 2026 | Viewed by 63 | Submission Open

Keywords: symptom burden; patient-reported outcomes; symptom assessment; symptom management; cancer survivorship; quality of life

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Immunotherapy for Acute Lymphoblastic Leukemia: Novel Strategies and Clinical Perspectives

edited by Paola Minetto and

Francesco Grimaldi

submission deadline 30 Jun 2026 | Viewed by 60 | Submission Open

Keywords: immunotherapy; CAR T-cell therapy; bispecific antibodies; antibody– drug conjugates; treatment resistance; clinical perspectives; clinical trial in ALL

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Progress in Targeted Nanotherapeutic Delivery Systems for Cancer Precision Medicine

edited by

Linlin Zhang

and Dhananjay Suresh

submission deadline 30 Jun 2026 | Viewed by 59 | Submission Open

Keywords: cancer therapy; drug delivery; tumor targeting; nanotechnology; precision medicine; immunotherapy; new approach methodologies (NAMs)

(This special issue belongs to the Section Methods and Technologies Development)

Ras-Directed Therapies: A Revolution

edited by

Naiara Perurena

submission deadline 30 Jun 2026 | Viewed by 58 | Submission Open

Keywords: Ras-driven cancers; Ras inhibitors; Ras degraders; Ras signaling; mechanisms of resistance; combination therapies

(This special issue belongs to the Section Cancer Therapy)

Magnetic Resonance in Cancer Research (2nd Edition)

edited by Qiuhong He and Marie-France Vidaver

submission deadline 30 Jun 2026 | Viewed by 57 | Submission Open

Keywords: magnetic resonance; cancer; MRI; MRS; MRSI; NMR; DWI; MR; molecular imaging

(This special issue belongs to the Section Methods and Technologies Development)

Fertility and Pregnancy in Cancer

edited by

Bettina Böttcher

submission deadline 30 Jun 2026 | Viewed by 38 | Submission Open

Keywords: cancer; gonadotoxic treatment; pregnancy; offspring; long term survivorship; fertility preservation

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Diagnostic and Pathological Markers in Human Cancer

edited by

Zuoren Yu

Shengqiong Deng

and Qian Zhao

submission deadline 30 Jun 2026 | Viewed by 16 | Submission Open

Keywords: cancer; biomarker; early diagnosis; pathological markers; prognostic model

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Advances in Therapeutic Strategies for Prostate Cancer

edited by Angelo Naselli and

Giacomo Maria Pirola

submission deadline 1 Jul 2026 | 5 articles | Viewed by 20752 | Submission Open

Keywords: immunotherapy; radiation therapy; hormone therapy; targeted therapies

(This special issue belongs to the Section Cancer Therapy)

Pediatric Brain Tumors: Symptoms, Diagnosis and Treatments

edited by Christian Ott and Julius Höhne

submission deadline 1 Jul 2026 | 3 articles | Viewed by 7727 | Submission Open

Keywords: MRI/CT scans; radiation therapy; chemotherapy; combined therapy

(This special issue belongs to the Section Cancer Therapy)

The Role of Radiotherapy, Immunotherapy and New Surgical Techniques in the Treatment of Lung Neoplasms

edited by

Elisa Meacci

submission deadline 1 Jul 2026 | 3 articles | Viewed by 7321 | Submission Open

Keywords: radiotherapy; immunotherapy; new surgical techniques; lung cancer

(This special issue belongs to the Section Cancer Therapy)

The Mediastinum—Pandora’s Box

edited by

Cesar A. Moran

submission deadline 1 Jul 2026 | Viewed by 540 | Submission Open

Keywords: mediastinum; thymus; imaging; surgery; thymoma; germ cell tumors

Clinical Trials for Diffuse Large B-Cell Lymphomas (DLBCL)

edited by

Erel Joffe

submission deadline 1 Jul 2026 | Viewed by 316 | Submission Open

Keywords: DLBCL; immunotherapy; drug combinations; elderly patients; ctDNA; biomarkers; radiotherapy; clinical trial management; artificial intelligence

(This special issue belongs to the Section Clinical Research of Cancer)

Advancing CAR-T Cell Therapy: The Next Evolution in Breast Cancer Treatment

edited by

Nethaji Muniraj

and

Arun Dharmarajan

submission deadline 1 Jul 2026 | Viewed by 176 | Submission Open

Keywords: CAR-T cell therapy; breast cancer; triple-negative breast cancer (TNBC); HER2-positive breast cancer; tumor microenvironment; immunotherapy

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

The Role of Opioid Therapy for Cancers

edited by Brian Le and

Aaron K. Wong

submission deadline 1 Jul 2026 | Viewed by 44 | Submission Open

Keywords: opioids; palliative care; chronic cancer pain

(This special issue belongs to the Section Cancer Therapy)

Metals in Cancer: From Molecular Mechanisms to Innovative Therapeutics

edited by

Katarina Zivancevic

submission deadline 5 Jul 2026 | Viewed by 56 | Submission Open

Keywords: essential and toxic metals; metal-induced carcinogenesis; metal homeostasis; metallotherapeutics; oxidative stress; tumor microenvironment; immune modulation; metabolic reprogramming; therapy resistance; drug delivery systems

(This special issue belongs to the Section Molecular Cancer Biology)

Microfluidic Technology in Cancer

edited by

Lanju Mei

and

Diganta Dutta

submission deadline 5 Jul 2026 | Viewed by 55 | Submission Open

Keywords: cancer cells separation; cancer cells isolation; cancer cells treatment; lab-on-a-chip technology; bio microfluidics; biomedical microdevices; biosensors; and detection in microfluidics

(This special issue belongs to the Section Methods and Technologies Development)

Perioperative Management and Cancer Outcomes (2nd Edition)

edited by

Daniela Ionescu

submission deadline 9 Jul 2026 | Viewed by 132 | Submission Open

Keywords: perioperative management; cancer treatment outcomes; onco-anesthesiology; preoperative risk assessment; enhanced recovery after surgery (ERAS); pain management; personalized medicine

(This special issue belongs to the Section Cancer Therapy)

Upper Tract Urothelial Carcinoma: Current Knowledge and Perspectives

edited by Katie S. Murray and Saum Ghodoussipour

submission deadline 10 Jul 2026 | 3 articles | Viewed by 7202 | Submission Open

Keywords: upper tract urothelial carcinoma; upper tract disease; urothelial cell carcinoma

(This special issue belongs to the Section Cancer Therapy)

Neuroendocrine Neoplasms: Pathogenesis, Diagnostics, and Therapy

edited by

Beata Jabłońska

submission deadline 10 Jul 2026 | 1 articles | Viewed by 5827 | Submission Open

Keywords: neuroendocrine neoplasms; pathogenesis; diagnostics; therapy

(This special issue belongs to the Section Cancer Therapy)

Clinicopathological Study of Gynecologic Cancer (2nd Edition)

edited by

Massimo Origoni

submission deadline 10 Jul 2026 | 1 articles | Viewed by 1181 | Submission Open

Keywords: gynecological oncology; gynecological cancer; female cancer; uterine cancer; ovarian cancer; endometrial cancer; cancerogenesis; cancer biology; cell transformation; cancer pathology; cancer biology

(This special issue belongs to the Section Clinical Research of Cancer)

Beyond Cancer: Enhancing Quality of Life for Cancer Survivors (Second Edition)

edited by

Jennifer Jones

, Maryam Lustberg and Muna Al-Khaifi

submission deadline 10 Jul 2026 | Viewed by 74 | Submission Open

Keywords: psychosocial oncology; cancer survivorship; long-term effects of cancer; psychoeducational interventions; nnovative care models; continuing education; knowledge translation

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Preoperative Optimisation in Patients Undergoing Cancer Surgery: 2nd Edition

edited by

Daniel Steffens

and

Cherry Koh

submission deadline 10 Jul 2026 | Viewed by 67 | Submission Open

Keywords: prehabilitation; medical optimization; exercise; nutrition; psychological interventions; surgery; cancer; surgical outcome; preoperative; clinical trials

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Molecular Biology, Diagnosis and Management of Endometrial Cancer

edited by

Georgios Androutsopoulos

Georgios Michail

and Thomas Vrekoussis

submission deadline 12 Jul 2026 | 4 articles | Viewed by 8778 | Submission Open

Keywords: endometrial cancer; molecular biology; lymph node dissection; sentinel lymph node mapping; sentinel lymph node dissection; surgery; systemic therapy; radiotherapy; fertility preservation; molecular targeted therapies

(This special issue belongs to the Section Molecular Cancer Biology)

Advances in Hodgkin Lymphoma (HL)

edited by

Antonino Carbone

submission deadline 15 Jul 2026 | 2 articles | Viewed by 3259 | Submission Open

Keywords: classic Hodgkin lymphoma; diagnostic challenges; tumour microenvironment; variability in disease extent; TME-targeted therapies; personalized treatment; relapsed/refractory cHL

(This special issue belongs to the Section Cancer Pathophysiology)

Advances in Clinical Surgery for Gynecological Cancers

edited by

Sebastian Szubert

submission deadline 15 Jul 2026 | 1 articles | Viewed by 1575 | Submission Open

Keywords: ovarian cancer; endometrial cancer; cervical cancer; gynecological surgery; gynecological oncology; reconstructive surgery; pelvic exenteration; supportive cancer care

(This special issue belongs to the Section Methods and Technologies Development)

Displaying special issue 851-900 on page 18 of 24.

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