Progress in Targeted Nanotherapeutic Delivery Systems for Cancer Precision Medicine
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Methods and Technologies Development".
Deadline for manuscript submissions: 30 June 2026 | Viewed by 15
Special Issue Editors
Interests: developing magnetic nanotechnology-based cancer therapies
Special Issue Information
Dear Colleagues,
Cancer remains one of the leading causes of death globally, compelling substantial investments in understanding tumor mechanisms and urging advancements in precision medicine. Still, the current therapy landscape is compounded with evolving tumor heterogeneity, complex tumor microenvironment, drug resistance, limitations of passive targeting, subpar pharmacokinetics, drug instability, and systemic toxicity. While newer inhibitors, RNAi drugs, and immunotherapy targets have provided strategic therapeutic solutions, effective transport of therapeutic molecules to the intended tumor site remains a major challenge in precision cancer therapy. Therefore, there is a clinical need to develop and explore innovative solutions to cancer drug delivery.
Pioneering initiatives to overcome the challenge have involved the use of healthcare-related nanomaterials. Such materials show great promise and potential in developing effective drug carriers that exhibit efficient and stable drug formulations, active targeting, unique theranostic properties, enhanced tumor penetration, reduced toxicity, and improved therapeutic efficacy. However, the successful development, scaling, and clinical translatability of nanomedicines have been lagging and difficult, warranting scientific innovation to address the critical gap. Thus, this Special Issue is dedicated to promoting and catalyzing efforts to drive scientific progress and breakthroughs in nanotechnology-mediated drug delivery strategies in cancer therapy. Importantly, this issue will rigorously focus on the synthesis rationale, nanomedicine’s biocompatibility, scalability, and reproducibility, efficiency in selective targeting and drug delivery, tumor penetration (in 3D tumoroids and animals), and therapeutic efficacy.
We invite investigators to contribute their original research articles or reviews that provide new insights into nanomaterial phenomena, synthesis, and its translation towards effective cancer drug delivery and personalized cancer therapy.
Dr. Linlin Zhang
Dr. Dhananjay Suresh
Guest Editors
Manuscript Submission Information
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Keywords
- cancer therapy
- drug delivery
- tumor targeting
- nanotechnology
- precision medicine
- immunotherapy
- new approach methodologies (NAMs)
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