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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Study on Surgical Treatment of Ovarian Cancer
edited by
submission deadline 25 Sep 2026 | 3 articles | Viewed by 1934
Keywords: ovarian cancer; surgical treatment; ovarian cancer prevention
(This special issue belongs to the Section Cancer Therapy)
Combination Immunotherapy for Cancer Treatment—2nd Edition submission deadline 25 Sep 2026 | 1 articles | Viewed by 1587
Keywords: immunotherapy; immune checkpoint inhibitor; cancer vaccine; novel cancer therapy; treatment
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Targeting the Vulnerabilities of Oncogene Activation (Second Edition)
edited by
submission deadline 25 Sep 2026 | Viewed by 569
Keywords: tumorigenesis; tumor-suppressor genes; oncogene; target
(This special issue belongs to the Section Methods and Technologies Development)
Acute Myeloid Leukemia: Updates on Diagnosis and Novel Management Strategies
edited by Ana Vidović
submission deadline 25 Sep 2026 | Viewed by 381
Keywords: acute myeloblastic leukemia; diagnosis; prognosis; intensive chemotherapy; target therapy; allogeneic stem cell transplantation
(This special issue belongs to the Section Clinical Research in Cancer)
Role of Iron Metabolism in Tumor Progression
edited by
submission deadline 25 Sep 2026 | Viewed by 380
Keywords: iron metabolism; ferroptosis; tumor microenvironment; oxidative stress; iron chelation therapy; ferritin; transferrin receptor; cancer metabolism; redox homeostasis; therapeutic targeting
(This special issue belongs to the Section Molecular Cancer Biology)
Clinical Pathology in Cancer: From Diagnosis to Precision Medicine
edited by
submission deadline 28 Sep 2026 | Viewed by 535 | Submission Open
Keywords: cancer biomarkers; precision medicine; histopathology; clinical pathology; diagnosis; prognostic/predictive biomarker
(This special issue belongs to the Section Cancer Pathophysiology)
Advances and Challenges in the Diagnosis and Treatment of Urological Malignancies (2nd Edition) submission deadline 30 Sep 2026 | 10 articles | Viewed by 22485 | Submission Open
Keywords: prostate cancer; bladder cancer; upper urinary tract tumors; kidney cancer; testicular tumors; molecular markers; lymph node metastasis; diagnosis; radical treatment; systemic treatment
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Advances in Soft Tissue and Bone Sarcoma (2nd Edition) submission deadline 30 Sep 2026 | 14 articles | Viewed by 19270 | Submission Open
Keywords: bone sarcoma; soft tissue sarcoma; prognosis; diagnosis; detection; molecular biomarkers; histopathology; treatment
(This special issue belongs to the Section Cancer Therapy)
Immunotherapy for Skin Cancers
edited by and Lara Valeska Maul-Duwendag
submission deadline 30 Sep 2026 | 4 articles | Viewed by 12810 | Submission Open
Keywords: melanoma; non-melanoma skin cancer; merkel cell carcinoma; kaposi sarcoma; cutaneous angi-osarcoma; immune checkpoint; immunotherapy
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Health Economic and Policy Issues Regarding Cancer
edited by
submission deadline 30 Sep 2026 | 5 articles | Viewed by 9622 | Submission Open
Keywords: cancer economics; health policy; cost-effectiveness; financial toxicity; healthcare disparities; value-based oncology
Neurosurgery Research on Brain Tumors: A Focus on Gliomas and Other Intra-Axial Brain Tumors
edited by , Carlo Giussani, Cesare Zoia and Daniele Bongetta
submission deadline 30 Sep 2026 | 2 articles | Viewed by 8174 | Submission Open
Keywords: neurosurgery; glioma; neuropsychology; neurophysiological monitoring; intraoperative imaging (including iMRI and iOUS); neuroanatomy; outcome; prognosis and quality of life; MRI (including fMRI, MR spectroscopy, perfusion and DTI tractography); radiogenomics; multimodal treatments; druggable targets; artificial intelligence and deep learning
(This special issue belongs to the Section Clinical Research in Cancer)
Cellular and Molecular Mechanisms of Malignant Nervous System Cancers
edited by
submission deadline 30 Sep 2026 | 7 articles | Viewed by 7894 | Submission Open
Keywords: medulloblastoma; pediatric glioma; neuroblastoma; diagnosis and prognostic markers; IDH, TERT, and EGFR mutations; DNA methylation; treatment approaches and strategies (chemotherapy, radiation therapy, immunotherapy, and targeted therapy); resistance mechanisms; tumor microenvironment; molecular characteristics of tumor heterogeneity
(This special issue belongs to the Section Molecular Cancer Biology)
The EGFR-Tyrosine Kinase Inhibitors (EGFR-TKIs) and Immune Checkpoint Inhibitors (ICIs) for Non-Small Cell Lung Cancer submission deadline 30 Sep 2026 | 3 articles | Viewed by 7372 | Submission Open
Keywords: non-small cell lung cancer; target therapy; EGFR-tyrosine kinase inhibitors; immunotherapy; immune checkpoint inhibitors; molecular analysis; surgery; precision medicine
(This special issue belongs to the Section Cancer Therapy)
Current Issues, Innovations, and Emerging Therapies in Thoracic Surgical Oncology
edited by Inderpal S. Sarkaria and Shamus Carr
submission deadline 30 Sep 2026 | 5 articles | Viewed by 7218 | Submission Open
Keywords: non-small cell lung cancer; esophageal cancer; thymic epithelial tumors; BAP1 malignant mesothelioma; robotic surgery; immunotherapy; cellular therapies; molecular imaging
Biomarkers for Therapy Response in Gastrointestinal Malignancies: Predicting Outcomes and Personalizing Care submission deadline 30 Sep 2026 | 5 articles | Viewed by 6930 | Submission Open
Keywords: immunotherapy; biomarkers; resistance mechanisms; predictive markers; clinical trials; translational research
(This special issue belongs to the Section Cancer Biomarkers)
Fertility Preservation and Hormonal Health in Oncology submission deadline 30 Sep 2026 | 4 articles | Viewed by 6855 | Submission Open
Keywords: oncofertility; fertility preservation; hormonal health; cancer survivorship; reproductive oncology
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Novel Perspectives in Hepato-Biliary and Pancreatic Cancer
edited by Tudor Mocan and Emil-Ioan Moiș
submission deadline 30 Sep 2026 | 4 articles | Viewed by 6740 | Submission Open
Keywords: HCC; cholangiocarcinoma; surgery; biliary drainage; pancreatic cancer; combination therapies
(This special issue belongs to the Section Cancer Therapy)
Multiple Myeloma: Diagnosis and Therapy submission deadline 30 Sep 2026 | 3 articles | Viewed by 6530 | Submission Open
Keywords: multiple myeloma; plasma cell disorders; relapsed and refractory multiple myeloma; blood and marrow transplant
(This special issue belongs to the Section Cancer Therapy)
Proteomic and Oncogenic Biomarkers in Gastrointestinal Cancer submission deadline 30 Sep 2026 | 4 articles | Viewed by 6326 | Submission Open
Keywords: tumor biomarkers; early detection; tumor progression; carcinogenesis; inflammatory mediators; gastrointestinal cancer; prognostic biomarkers
(This special issue belongs to the Section Cancer Biomarkers)
Contemporary Lung Cancer Nodal Staging and Evolving Therapeutic Paradigms submission deadline 30 Sep 2026 | 8 articles | Viewed by 6102 | Submission Open
Keywords: ninth TNM classification; nodal staging; endoscopic/endobronchial ultrasound; neoadjuvant/adjuvant therapy; biomarker testing
(This special issue belongs to the Section Cancer Therapy)
Exercise Interventions for People Living with Cancer: Advances in Knowledge and Implementation
edited by and Chris Swain
submission deadline 30 Sep 2026 | 3 articles | Viewed by 5967 | Submission Open
Keywords: cancer; survivorship; exercise; physical activity; implementation
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Advances in Lung Cancer Treatment Strategies submission deadline 30 Sep 2026 | 5 articles | Viewed by 5965 | Submission Open
Keywords: lung cancer; immunotherapy; immune checkpoint inhibitors; chemoimmunotherapy; target therapy; biomarkers; non-small cell lung cancer; precision medicine
(This special issue belongs to the Section Cancer Therapy)
State-of-the-Art Research on Multiple Myeloma Progression: 2nd Edition
edited by
submission deadline 30 Sep 2026 | 3 articles | Viewed by 5639 | Submission Open
Keywords: multiple myeloma; novel targets; novel therapies; molecular therapy; immunotherapy
(This special issue belongs to the Section Cancer Therapy)
Clinical Applications of Precision Diagnosis for Thyroid Cancers and Its Clinical Use for Treatments Choice
edited by , Silvia Martina Ferrari and
submission deadline 30 Sep 2026 | 2 articles | Viewed by 5505 | Submission Open
Keywords: thyroid cancer; precision diagnosis; clinical management; molecular tests; molecular therapeutic targets; thyroid cancer epidemiology; artificial intelligence; health inequalities
(This special issue belongs to the Section Clinical Research in Cancer)
The Cellular Ecosystem of Cancer: New Insights into Cell Biology
edited by Xiaochao Tan and
submission deadline 30 Sep 2026 | 3 articles | Viewed by 5334 | Submission Open
Keywords: cell organelle; ER; mitochondria; lysosome; Golgi; secretion; tumor microenvironment
(This special issue belongs to the Section Molecular Cancer Biology)
The Development of Effective Therapy Targeting the Microenvironment of Cancer (2nd Edition) submission deadline 30 Sep 2026 | 3 articles | Viewed by 5110 | Submission Open
Keywords: cancer; tumor microenvironment; cancer therapy; cancer cell; animal level
(This special issue belongs to the Section Tumor Microenvironment)
Advances in Brain Tumors
edited by
submission deadline 30 Sep 2026 | 2 articles | Viewed by 4696 | Submission Open
Keywords: diagnosis; biomarker; treatment; brain tumors
(This special issue belongs to the Section Clinical Research in Cancer)
Cancer Survivors: Late Effects of Cancer Therapy
edited by
submission deadline 30 Sep 2026 | 3 articles | Viewed by 4434 | Submission Open
Keywords: late effects; cancer survivorship; treatment toxicity; long-term outcomes
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Robotic and Thoracoscopic Surgery for Thoracic Oncology
edited by
submission deadline 30 Sep 2026 | 1 articles | Viewed by 3846 | Submission Open
Keywords: robotic-assisted thoracic surgery; video-assisted thoracoscopic surgery (VATS); lung cancer surgery; esophageal cancer; thymic tumors; minimally invasive surgery; pleural tumors; chest wall tumors; mediastinal surgery; thoracic oncology
(This special issue belongs to the Section Clinical Research in Cancer)
Management of Orbital Tumors
edited by
submission deadline 30 Sep 2026 | 1 articles | Viewed by 3588 | Submission Open
Keywords: orbital tumor; diagnostic; multidisciplinary approaches; personalized treatment; imaging techniques
(This special issue belongs to the Section Clinical Research in Cancer)
Multimodal Artificial Intelligence/Machine Learning Applications in Malignant Tumors: Diagnosis, Prognosis, and Management
edited by and Stefan Haider
submission deadline 30 Sep 2026 | 1 articles | Viewed by 3486 | Submission Open
Keywords: machine learning; radiomics; cancer imaging; malignancy; survival
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Radiotherapy for Head and Neck Squamous Cell Carcinoma (2nd Edition)
edited by and Ida D'Onofrio
submission deadline 30 Sep 2026 | 2 articles | Viewed by 3284 | Submission Open
Keywords: head and neck squamous cell carcinoma; radiotherapy; biomarker; chemoradiotherapy; head and neck cancers
(This special issue belongs to the Section Cancer Therapy)
Advances in Pathogenesis and Pathology Diagnosis of Gynecologic Cancers
edited by
submission deadline 30 Sep 2026 | 4 articles | Viewed by 3228 | Submission Open
Keywords: gynecologic cancers; molecular pathology; tumor pathogenesis; diagnostic biomarkers; precision medicine; endometrial carcinoma; ovarian cancer; cervical cancer; histopathology; translational research
Cancer and Melatonin: Updates on Current Findings
edited by
submission deadline 30 Sep 2026 | 2 articles | Viewed by 3138 | Submission Open
Keywords: cancer; melatonin; oxidative stress; inflammation; antioxidant defense
Novel Advancements in Prostate Cancer Surgery: Indications and Techniques
edited by Valerio Santarelli and
submission deadline 30 Sep 2026 | 2 articles | Viewed by 3046 | Submission Open
Keywords: radical prostatectomy; prostate cancer; technology; minimally invasive surgery
(This special issue belongs to the Section Cancer Therapy)
Clinical Trials and Translational Research in Multiple Myeloma
edited by Laszlo Varoczy
submission deadline 30 Sep 2026 | 2 articles | Viewed by 2989 | Submission Open
Keywords: multiple myeloma; disease evolution; translational research; personalizing therapy; clinical trial
(This special issue belongs to the Section Clinical Research in Cancer)
Chromatin-Remodeling Factors in Cancer Cells
edited by
submission deadline 30 Sep 2026 | 1 articles | Viewed by 2925 | Submission Open
Keywords: chromatin remodeling; transcription factors; epigenetic therapy; cancer epigenomics; SWI/SNF complex; CRISPR functional screens; single-cell epigenomics; gene regulation in cancer; therapy resistance; targeted cancer therapies
(This special issue belongs to the Section Cancer Pathophysiology)
Hematologic Malignancies: Clinical Features and Prognostic Indicators
edited by Danijela Leković
submission deadline 30 Sep 2026 | 3 articles | Viewed by 2708 | Submission Open
Keywords: leukemia; myelodysplastic syndrome; myeloproliferative neoplasms; lymphoma; multiple myeloma; diagnosis; prognosis; molecular markers; infections; survival; machine learning
(This special issue belongs to the Section Clinical Research in Cancer)
Screening, Early Detection and Therapeutic Advances in Gastrointestinal Cancers submission deadline 30 Sep 2026 | 2 articles | Viewed by 2658 | Submission Open
Keywords: gastrointestinal cancer; screening; advanced endoscopy; imaging platforms; circulating biomarkers; molecular profiling
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
miRNAs in Targeted Cancer Therapy
edited by Mustafa Özen
submission deadline 30 Sep 2026 | 2 articles | Viewed by 2580 | Submission Open
Keywords: miRNA; micro-RNA; targeted therapy; cancer treatment; solid tumors; hematological malignancies; non-coding RNAs; epigenetic regulation; cancer therapeutics; gene therapy
(This special issue belongs to the Section Cancer Therapy)
Advances in PET/CT Imaging in Cancer Management
edited by Jasna M. Mihailovic and Mihaela Raluca Mititelu
submission deadline 30 Sep 2026 | 3 articles | Viewed by 2525 | Submission Open
Keywords: PET/CT imaging; oncology; staging; restaging; treatment monitoring; recurrence detection
(This special issue belongs to the Section Methods and Technologies Development)
Targeting RNA to Improve Cancer Precision Medicine
edited by , Anna Grimaldi and Chiara Tammaro
submission deadline 30 Sep 2026 | 1 articles | Viewed by 2480 | Submission Open
Keywords: cancer; RNA therapy; RNA delivery; RNA; miRNA; mRNA; siRNA; oligonucleotides; aptamers; precision medicine
(This special issue belongs to the Section Cancer Therapy)
Ablation Treatment for Malignant Tumors submission deadline 30 Sep 2026 | 2 articles | Viewed by 2307 | Submission Open
Keywords: ablative therapies; thermal ablation; image-guided therapy; minimally invasive; radiofrequency ablation (RFA); microwave ablation (MWA); cryoablation; irreversible electroporation (IRE); malignant tumors; oligometastatic disease; immunotherapy combinations; interventional oncology
(This special issue belongs to the Section Cancer Therapy)
Advances in Cancer Targeted Therapy
edited by Ponniah Selvakumar
submission deadline 30 Sep 2026 | 2 articles | Viewed by 2132 | Submission Open
Keywords: targeted therapy; cancer treatment; molecular targets; signaling pathways; angiogenesis inhibition; artificial intelligence (AI); single-cell technologies; informatics; personalized medicine
(This special issue belongs to the Section Cancer Therapy)
Senescence and Cell Plasticity in Cancer Development
edited by and Elena Aguado-Domínguez
submission deadline 30 Sep 2026 | 1 articles | Viewed by 2070 | Submission Open
Keywords: cellular senescence; cell plasticity; stem cells; SASP; therapy resistance; tumor microenvironment; cancer development
(This special issue belongs to the Section Molecular Cancer Biology)
Cell Cycle Dysregulation in Cancers
edited by Radoslav Janostiak
submission deadline 30 Sep 2026 | 2 articles | Viewed by 1952 | Submission Open
Keywords: cell cycle regulation; proliferation-quiescence decision; post translational regulation; quiescence maintenance; senescence escape; environmental stress adaptation; minimal residual disease; cell cycle checkpoints
(This special issue belongs to the Section Molecular Cancer Biology)
Clinical and Surgical Outcomes in the Management of Extremity Soft Tissue Sarcomas (2nd Edition)
edited by
submission deadline 30 Sep 2026 | 1 articles | Viewed by 1722 | Submission Open
Keywords: soft tissue sarcoma; outcome; limb salvage; radiotherapy; surgery
(This special issue belongs to the Section Cancer Therapy)
Gut Microbiota and Inflammation in Colorectal Tumor Development and Progression
edited by and Irene Marafini
submission deadline 30 Sep 2026 | 1 articles | Viewed by 1714 | Submission Open
Keywords: gut microbiota; colorectal cancer; inflammation; tumor microenvironment; mucosal immunity; microbial metabolites; immune–microbiota interactions; inflammatory bowel disease; cancer progression
Imaging and Liquid Biopsy Biomarkers for Cancer Diagnosis and Treatment (2nd Edition) submission deadline 30 Sep 2026 | 1 articles | Viewed by 1694 | Submission Open
Keywords: cancer imaging; liquid biopsy; cancer diagnosis; treatment response; prognosis; metastasis; circulating tumor cells; disseminated tumor cells; circulating tumor DNA; circulating tumor RNA
(This special issue belongs to the Section Methods and Technologies Development)
Artificial Intelligence (AI), Robotics, and Cancer Surgery
edited by Zaid M. Abdelsattar
submission deadline 30 Sep 2026 | 1 articles | Viewed by 1684 | Submission Open
Keywords: cancer surgery; artificial intelligence; robotics surgery; surgical outcome; decision-making
(This special issue belongs to the Section Methods and Technologies Development)
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