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Management of Orbital Tumors

A Special Issue of Cancers (ISSN 2072-6694) belonging to the section "Clinical Research in Cancer".

Deadline for manuscript submissions: 30 September 2026 | Viewed by 3397

Editor


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Guest Editor
1. Department of Ophthalmology, Amsterdam UMC Location University of Amsterdam, 1053 VE Amsterdam, The Netherlands
2. Cancer Center Amsterdam, Cancer Treatment and Quality of Life, 1081 HV Amsterdam, The Netherlands
Interests: ophthalmology; orbit, oculoplastics and lacrimal surgery; orbital tumors; graves orbitopathy; endoscopic orbital and lacrimal surgery; functional imaging
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We are pleased to announce the call for submissions to a Special Issue of Cancers, focusing on the topic of “Management of Orbital Tumors”. Orbital tumors represent a particularly challenging subset of oncological diseases due to their critical anatomical location and the necessity of preserving visual and neurological function. This aggressive and complex group of pathologies demands highly specialized, multidisciplinary approaches to optimize diagnostic accuracy, treatment efficacy, and functional outcomes.

This Special Issue aims to provide a comprehensive overview of the current knowledge and advancements in the management of orbital tumors, from enhanced diagnostic techniques to innovative therapeutic strategies. We invite the submission of original research articles and reviews that cover various aspects of orbital oncology, including but not limited to:

  1. Advanced imaging techniques for improved tumor localization and characterization;
  2. Histopathological and molecular markers for diagnosis and prognosis;
  3. Minimally invasive and precision-guided surgical approaches;
  4. Applications of radiotherapy and proton beam therapy;
  5. Systemic therapies, including chemotherapy and targeted agents;
  6. Multidisciplinary treatment planning and patient-specific therapeutic strategies.

All submitted articles will undergo a rigorous peer review process to ensure the highest scientific quality and relevance to the field. We encourage contributions from researchers, clinicians, surgeons, radiologists, and other experts involved in the care of patients with orbital tumors.

By consolidating the latest research findings and clinical experiences, we aim to enhance our understanding of orbital oncology and foster the development of personalized and effective treatment strategies. We believe that your valuable contributions will significantly contribute to the success of this Special Issue.

Should you have any questions, require further information, or need any assistance, please do not hesitate to reach out to us. We are here to support and facilitate your participation in this Special Issue.

Thank you for your attention to this matter, and we look forward to receiving your valuable submissions.

You may choose our Joint Special Issue in Current Oncology.

Prof. Dr. Peerooz Saeed
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • orbital tumor
  • diagnostic
  • multidisciplinary approaches
  • personalized treatment
  • imaging techniques

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Published Papers (1 paper)

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Review

12 pages, 14490 KB  
Review
Tumors of the Lacrimal Drainage System: Diagnosis and Management
by Ernest Iakovlev, Kaveh Vahdani, David H. Verity, Simon Gane and Geoffrey E. Rose
Cancers 2026, 18(12), 1894; https://doi.org/10.3390/cancers18121894 - 10 Jun 2026
Viewed by 2946
Abstract
Tumors of the lacrimal drainage system are rare and include benign and malignant variants. Their presentation frequently mimics inflammatory or obstructive lacrimal disease, which often results in delayed diagnosis and diagnostic uncertainty. A high index of suspicion, appropriate imaging, and timely biopsy are [...] Read more.
Tumors of the lacrimal drainage system are rare and include benign and malignant variants. Their presentation frequently mimics inflammatory or obstructive lacrimal disease, which often results in delayed diagnosis and diagnostic uncertainty. A high index of suspicion, appropriate imaging, and timely biopsy are required to verify the histology and guide management. Surgical excision remains the cornerstone of treatment for most lesions, with the aim of achieving histologically clear margins. Advances in endoscopic and combined surgical approaches have enabled radical tumor resection whilst reducing morbidity and improving globe preservation. Adjuvant radiotherapy is commonly employed in malignant disease, while systemic chemotherapy, immunotherapy, and targeted therapies may be considered in selected advanced or recurrent cases. Emerging molecular insights and evolving surgical techniques may further refine future treatment strategies. This review summarizes current evidence and clinical principles to provide a practical framework for the diagnosis and management of lacrimal drainage system tumors. Full article
(This article belongs to the Special Issue Management of Orbital Tumors)
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