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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Feature Paper in Section ‘Cancer Epidemiology and Prevention’ in 2025

edited by Roger Anderson and

Paweł Koczkodaj

submission deadline 31 Dec 2025 | 4 articles | Viewed by 6550 | Submission Open

Keywords: cancer prevention; cancer epidemiology; health policy; public health; global health; health education; health promotion

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Feature Papers in Section “Methods and Technologies Development” in 2025

edited by

Damiano Caruso

and

Marta Zerunian

submission deadline 31 Dec 2025 | 1 articles | Viewed by 6352 | Submission Open

Keywords: innovative diagnostic technology; artificial intelligence; cancer diagnosis; personalized treatment; diagnostic and therapeutic strategies

(This special issue belongs to the Section Methods and Technologies Development)

Latest Advancements in Health-Related Quality of Life Research in Cancer Survivorship (2nd Edition)

edited by

Richard Crevenna

and

Thomas Licht

submission deadline 31 Dec 2025 | 4 articles | Viewed by 6058 | Submission Open

Keywords: cancer survivors; oncology; psycho-oncology; health-related quality of life; patient-reported outcome measures; self-report

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Advances in Breast and Gynecologic Cancer Pathology: Molecular Insights and Therapeutic Implications

edited by

Hisham Bahmad

submission deadline 31 Dec 2025 | 1 articles | Viewed by 5869 | Submission Open

Keywords: breast cancer; gynecologic malignancies; diagnostic pathology; molecular biomarkers; histopathology; cytopathology; prognostic markers; targeted therapy

(This special issue belongs to the Section Cancer Pathophysiology)

Clear Cell Renal Cell Carcinoma 2024–2025

edited by

José I. López

and

Claudia Manini

submission deadline 31 Dec 2025 | 2 articles | Viewed by 5736 | Submission Open

Keywords: clear cell renal cell carcinoma; pathology; diagnosis; hypoxia; intratumor heterogeneity; immune checkpoint blockage antiangiogenic therapy

(This special issue belongs to the Section Cancer Pathophysiology)

New Perspectives in the Management of Central Nervous System (CNS) Tumors

edited by

Alessia Pellerino

, Francesco Bruno and

Teresa Somma

submission deadline 31 Dec 2025 | 2 articles | Viewed by 5170 | Submission Open

Keywords: gliomas; brain metastases; leptomeningeal metastases; liquid biopsy; neuroradiological tools; brain surgery; targeted therapy; immunotherapy; clinical trials; molecular factors

(This special issue belongs to the Section Cancer Therapy)

Molecular Mechanisms in Bone and Soft Tissue Sarcomas

edited by

Alexander L. Lazarides

and Zachary D.C. Burke

submission deadline 31 Dec 2025 | 2 articles | Viewed by 4733 | Submission Open

Keywords: sarcoma; bone sarcoma; soft tissue sarcoma; osteosarcoma; molecular level; translation

(This special issue belongs to the Section Molecular Cancer Biology)

New Insights on Management of Acute Lymphoblastic Leukemia in the Contemporary Era

edited by Talha Badar

submission deadline 31 Dec 2025 | 1 articles | Viewed by 4629 | Submission Open

Keywords: B-cell ALL; T-cell ALL; MRD in ALL; Ph+ve ALL; CAR T-cells; NGS-MRD; menin inhibitors; blinatumomab; inotuzumab; ponatinib; BCR-ABL1; TKI

(This special issue belongs to the Section Cancer Therapy)

Advances in Ovarian Cancer Treatment: Past, Present and Future

edited by Dimitrios Tsolakidis and Dimitrios Zouzoulas

submission deadline 31 Dec 2025 | 2 articles | Viewed by 4463 | Submission Open

Keywords: ovarian cancer; cytoreductive surgery; HIPEC; chemotherapy; immunotherapy

(This special issue belongs to the Section Cancer Therapy)

Burkitt Lymphoma: From Pathogenesis to Current Treatments

edited by Lorenzo Leoncini and

German K. Ott

submission deadline 31 Dec 2025 | 2 articles | Viewed by 4455 | Submission Open

Keywords: Burkitt lymphoma; high-grade B-cell lymphoma; EBV; NGS; whole-exome sequencing; RNAseq; methylation analysis; tumor microenvironment; immunotherapy; chemotherapy

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Advances in Diagnostics and Prognostics in the Management of Intrathoracic Malignancies

edited by Akshay Jatin Patel and Marcus Taylor

submission deadline 31 Dec 2025 | 2 articles | Viewed by 4043 | Submission Open

Keywords: intrathoracic malignancies; diagnostics; prognostics; molecular biomarkers; radiomics; artificial intelligence; immunobiological parameters; personalized therapy

(This special issue belongs to the Section Methods and Technologies Development)

Endometrial Cancer—from Diagnosis to Management

edited by Mingxin Shi and

Xiang Zhao

submission deadline 31 Dec 2025 | 2 articles | Viewed by 4013 | Submission Open

Keywords: endometrial cancer; prognosis; diagnosis; novel biomarker; immunotherapy; targeted therapy; prevention

(This special issue belongs to the Section Cancer Therapy)

Oral Cancer: Prevention and Early Detection (2nd Edition)

edited by

Gianluca Tenore

and

Umberto Romeo

submission deadline 31 Dec 2025 | 2 articles | Viewed by 3869 | Submission Open

Keywords: oral cancer; oral squamous cell carcinoma; alcohol and tobacco; human papillomavirus (HPV); biomarkers; biopsy and liquid biopsy; oral potentially malignant disorders (OPMDs); oral pathology and oral medicine; oral and maxillofacial surgery; radiotherapy and chemotherapy

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Innovations in Addressing Disparities in Cancer

edited by

Rajesh Singh

and

Shailesh Singh

submission deadline 31 Dec 2025 | 1 articles | Viewed by 3813 | Submission Open

Keywords: artificial intelligence on health equity; artificial intelligence and machine learning technologies in cancer care; genomic testing and biomarkers; AI in social determinants of health; health justice; precision medicine and health informatics; innovative cancer care delivery model for overcoming health disparity; equity lens; racial differences in the immunological landscape; racial differences in treatment and disease outcome

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Feature Papers in the Section “Cancer Therapy” in 2025

edited by

Abdullah Esmail

, Qiang Wang and

Hiroyuki Takei

submission deadline 31 Dec 2025 | 3 articles | Viewed by 3540 | Submission Open

Keywords: chemotherapy; immunotherapy for cancer; oncology; systemic treatment and targeted therapy.

(This special issue belongs to the Section Cancer Therapy)

Novel Therapeutic Targets for Metastatic Lung Cancer

edited by

Andrea De Giglio

submission deadline 31 Dec 2025 | 1 articles | Viewed by 3536 | Submission Open

Keywords: metastatic lung cancer; targeted therapy; immunotherapy; resistance mechanisms; tumor microenvironment; biomarkers; novel drug targets; translational oncology; precision medicine; epigenetic modulation

(This special issue belongs to the Section Cancer Therapy)

Palliative Care and Pain Management in Cancer

edited by María Fernández-Gonzáles and Moira O'Connor

submission deadline 31 Dec 2025 | 1 articles | Viewed by 3206 | Submission Open

Keywords: pain; quality of life; palliative care; non-pharmacological; pharmacological; cancer; metastasis; advanced cancer

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Chemotherapy and Immunotherapy of Lung Cancer

edited by

Sonia Vallet

and Klaus Hackner

submission deadline 31 Dec 2025 | 1 articles | Viewed by 3140 | Submission Open

Keywords: immune checkpoint inhibitors; immunotherapy; lung cancer; programmed-death ligand; chemoimmunotherapy; non-small-cell lung cancer; small-cell lung cancer

(This special issue belongs to the Section Cancer Therapy)

Surgical Innovations in Advanced Gastric Cancer

edited by Ugo Elmore, Francesco Puccetti and Andrea Cossu

submission deadline 31 Dec 2025 | 3 articles | Viewed by 3019 | Submission Open

Keywords: gastric cancer; gastrectomy; oligometastatic cancer; recurrence; peritoneal carcinomatosis; multimodal management

(This special issue belongs to the Section Cancer Therapy)

Advances in the Molecular Biology of Sarcoma and Drug Development

edited by Francis Hornicek and

Zhenfeng Duan

submission deadline 31 Dec 2025 | 1 articles | Viewed by 2948 | Submission Open

Keywords: sarcoma; sarcoma models; kinases; drug development; multidrug resistance; targeted therapy; immunotherapy

(This special issue belongs to the Section Molecular Cancer Biology)

Breast Cancer Research and Treatment

edited by

Huaitian Liu

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2890 | Submission Open

Keywords: breast cancer; tumor microenvironment; immune microenvironment; intratumoral heterogeneity; immunotherapy

(This special issue belongs to the Section Tumor Microenvironment)

New Insights into Kidney Disease Development and Therapy Strategies

edited by

José I. López

and

Claudia Manini

submission deadline 31 Dec 2025 | 1 articles | Viewed by 2769 | Submission Open

(This special issue belongs to the Section Cancer Therapy)

Advanced Ovarian Cancer (2nd Edition)

edited by

Sheng-Mou Hsiao

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2602 | Submission Open

Keywords: advanced ovarian cancer; medical treatment; surgical treatment; hyperthermic intraperitoneal chemotherapy; intraperitoneal chemotherapy

(This special issue belongs to the Section Cancer Therapy)

Advances in the Management of Oropharyngeal Cancer: Navigating the HPV-Associated Landscape

edited by Jon Mallen-St Clair

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2554 | Submission Open

Keywords: oropharyngeal cancer; human papillomavirus; clinical trials; transoral robotic surgery; epidemiology; HPV-related oropharyngeal cancer

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Lymphoma Biology, Pathology and Stem Cells

edited by

Mingyi Chen

submission deadline 31 Dec 2025 | 1 articles | Viewed by 2221 | Submission Open

Keywords: lymphoma biology; pathology; CAR-T; immunotherapy; stem cell transplant

(This special issue belongs to the Section Cancer Pathophysiology)

At the Interface of Genetics, Epigenetics, and Metabolism in Cancer: 2nd Edition

edited by

Kenta Masui

and

Linlin Guo

submission deadline 31 Dec 2025 | 2 articles | Viewed by 1973 | Submission Open

Keywords: cancer metabolism; epigenetic reprogramming; histone modification; DNA methylation; chromatin structure; intermediary metabolites; microenvironment; mTOR complexes; glioblastoma

(This special issue belongs to the Section Cancer Pathophysiology)

Chromatin-Remodeling Factors in Cancer Cells

edited by

Sudhakar Jha

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1839 | Submission Open

Keywords: chromatin remodeling; transcription factors; epigenetic therapy; cancer epigenomics; SWI/SNF complex; CRISPR functional screens; single-cell epigenomics; gene regulation in cancer; therapy resistance; targeted cancer therapies

(This special issue belongs to the Section Cancer Pathophysiology)

Accelerated Partial Breast Irradiation

edited by Roxolyana Abdah-Bortnyak

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1506 | Submission Open

Keywords: radiotherapy; accelerated partial breast irradiation; breast cancer; intraoperative radiotherapy; external beam radiotherapy; brachytherapy

(This special issue belongs to the Section Cancer Therapy)

Cancers in Chronic HIV Infection

edited by Diego Ripamonti

submission deadline 31 Dec 2025 | 1 articles | Viewed by 628 | Submission Open

Keywords: cancer; HIV; AIDS; cancer screening; hematologic malignancy; Kaposi sarcoma; HPV; anal cancer; lymphoma

(This special issue belongs to the Section Infectious Agents and Cancer)

Facial Paralysis in Cancer Patients—from Diagnosis to Treatment and Facial Reanimation

edited by

Barbara Kofler

, Niels van Heerbeek, Giulia Molinari and Benedikt Hofauer

submission deadline 31 Dec 2025 | Viewed by 581 | Submission Open

Keywords: facial nerve; facial nerve reanimation; head and neck cancer; facial reconstructive surgery

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Stereotactic Body Radiotherapy in Gynecologic Malignancies—a Practical Framework of SBRT, Chemoradiotherapy and Immunotherapy

edited by Antonio Pontoriero

submission deadline 31 Dec 2025 | Viewed by 394 | Submission Open

Keywords: SBRT; gynecologic cancer; chemoradiotherapy; immunotherapy; oligometastatic; oligoecurrent; oligopersistent; reirradiation

(This special issue belongs to the Section Cancer Therapy)

Views and Perspectives of Robot-Assisted Liver Surgery (2nd Edition)

edited by

Roland S. Croner

, Ibrahim Dagher and

Andrew A. Gumbs

submission deadline 31 Dec 2025 | Viewed by 374 | Submission Open

Keywords: robotic; liver surgery; liver resection; hepatectomy; minimally invasive; artificial intelligence

(This special issue belongs to the Section Cancer Therapy)

Surgical Aspects of Ovarian/Tubal/Peritoneal Cancer Management

edited by

Neville F. Hacker

and

Jacobus van der Velden

submission deadline 31 Dec 2025 | Viewed by 359 | Submission Open

Keywords: primary cytoreduction; interval cytoreduction; neoadjuvant chemotherapy

(This special issue belongs to the Section Cancer Therapy)

Clinical and Biological Studies of Pediatric Adrenocortical Tumors, Pheochromocytomas and Paragangliomas

edited by

Ronald R. de Krijger

, Verena Wiegering and

Maria Candida Barisson Villares Fragoso

submission deadline 31 Dec 2025 | Viewed by 286 | Submission Open

Keywords: adrenal gland; pheochromocytoma; paraganglioma; adrenocortical adenoma; adrenocortical carcinoma; pediatric; adrenal tumor

(This special issue belongs to the Section Pediatric Oncology)

Head and Neck Cancer Surgery and Rehabilitation: A Bridge Between Medicine and Dentistry for Reconstruction with Regeneration

edited by

Shahram M. Ghanaati

and Samuel Ebele Udeabor

submission deadline 31 Dec 2025 | Viewed by 242 | Submission Open

Keywords: oral squamous cell carcinoma; oral cancer; head and neck cancer; odontogenic tumors; OSCC management; tumor recurrence; tumor metastasis; adjuvant therapy; biomaterials for maxillofacial reconstruction; tissue regeneration; cancer rehabilitation

(This special issue belongs to the Section Cancer Therapy)

Oxidative Stress-Mediated Regulation of Specific Signaling Pathways in Skin Cancers

edited by

Sanjay Premi

and

Jyoti Srivastava

submission deadline 31 Dec 2025 | Viewed by 233 | Submission Open

Keywords: reactive oxygen species; reactive nitrogen species; oxidative stress; epigenetic regulation; UV-exposure; skin pigmentation; skin cancer; melanoma

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Neoadjuvant Chemotherapy in Pancreatic Cancer

edited by

Casper H. J. Van Eijck

submission deadline 31 Dec 2025 | Viewed by 226 | Submission Open

Keywords: neoadjuvant chemotherapy; pancreatic cancer; treatment decision

(This special issue belongs to the Section Cancer Therapy)

Contemporary Trends and Advances in Minimally Invasive and Endoscopic Management of Genitourinary Malignancies

edited by

Francesco Del Giudice

submission deadline 31 Dec 2025 | Viewed by 210 | Submission Open

Keywords: robotic surgery; laparoscopic surgery; endourology; urologic oncology; prostate cancer; urothelial cancer; kidney cancer; testicular cancer; single-port surgery; image-guided surgery; surgical outcomes; oncologic outcomes; advanced surgical techniques; precision medicine

(This special issue belongs to the Section Cancer Therapy)

Faulty Ribosome Biogenesis and Cancer: Mechanisms and Therapeutic Perspectives

edited by

Paola Bellosta

submission deadline 31 Dec 2025 | Viewed by 201 | Submission Open

Keywords: ribosome biogenesis; ribosomal proteins; nucleolar stress; genomic instability; oncoribosome; ribosomapathies; ribosome-targeting drugs; cancer biomarkers; animal models

(This special issue belongs to the Section Cancer Biomarkers)

Advances in Genitourinary Cancer: Biomarkers, Immunotherapy and Novel Therapeutics

edited by Lingbin Meng

submission deadline 31 Dec 2025 | Viewed by 201 | Submission Open

Keywords: genitourinary cancer; biomarkers; immunotherapy; targeted therapy; chemotherapy; drug resistance; tumor microenvironment; liquid biopsy; ctDNA; precision oncology

(This special issue belongs to the Section Cancer Therapy)

Hippo Signaling in Cancer (2nd Edition)

edited by

Michel Ouellette

and

Ying Yan

submission deadline 31 Dec 2025 | Viewed by 168 | Submission Open

Keywords: Hippo signaling; Salvador– Warts– Hippo (SWH) pathway; YAP/TAZ; cancer development; progression; metastasis; therapeutic resistance

(This special issue belongs to the Section Tumor Microenvironment)

Advances in Minimally Invasive Surgery for Colorectal Cancer

edited by Jonathan S. Abelson and Christine A. Schad

submission deadline 31 Dec 2025 | Viewed by 165 | Submission Open

Keywords: colorectal cancer; minimally invasive surgery; endoscopic surgery; endoluminal surgery; laparoscopic surgery; ro-botic surgery; single incision laparoscopic surgery; postoperative outcomes; survival

(This special issue belongs to the Section Cancer Therapy)

Tumor Microenvironment of Gynecological Tumors

edited by

Zahid Pranjol

and

Dmitry Aleksandrovich Zinovkin

submission deadline 10 Jan 2026 | 2 articles | Viewed by 1967 | Submission Open

Keywords: tumor microenvironment; gynecological cancers; immunomodulation; cancer-associated fibroblasts; angiogenesis; cancer-like stem cells; extracellular matrix; immune evasion; cell signaling; therapeutics

(This special issue belongs to the Section Tumor Microenvironment)

Neoadjuvant Therapy of Breast Cancer

edited by

Hiroyuki Takei

and Takaaki Fujii

submission deadline 15 Jan 2026 | 9 articles | Viewed by 25487 | Submission Open

Keywords: neoadjuvant systemic therapy; chemotherapy; endocrine therapy; molecular targeted therapy; molecular subtypes; response-guided therapy; clinical trials

(This special issue belongs to the Section Cancer Therapy)

Cervical Cancer: Study on Molecular Landscape and Protein Biomarkers. Current Diagnostic and Therapeutic Capabilities

edited by

Christopher Kobierzycki

and

Piotr Dzięgiel

submission deadline 15 Jan 2026 | 7 articles | Viewed by 15864 | Submission Open

Keywords: cervical cancer; cervical dysplasia; human papilloma virus (HPV); tumor markers; cancerogenesis; genotyping

(This special issue belongs to the Section Molecular Cancer Biology)

Novel Advances in the Molecular Understanding of Myeloproliferative Neoplasms (MPNs)

edited by Wei Chen, Fei Li and

Qiang Jeremy Wen

submission deadline 15 Jan 2026 | 4 articles | Viewed by 12096 | Submission Open

Keywords: MPNs; ET; PV; PMF; post-PV-MF; post-ET-MF; MDS/MPN; JAK2

(This special issue belongs to the Section Molecular Cancer Biology)

Clinical and Research Progress in the Resection of Gastro-Esophageal Cancer

edited by Biniam Kidane

submission deadline 15 Jan 2026 | 5 articles | Viewed by 9350 | Submission Open

(This special issue belongs to the Section Clinical Research of Cancer)

New Insights into Cancer Immunotherapy: From Immune Cell to Clinical Practice

edited by Xiaotong Song

submission deadline 15 Jan 2026 | 5 articles | Viewed by 8736 | Submission Open

Keywords: T cell therapy; cancer immunotherapy; CAR T cells; immune checkpoint modulation; tumor microenvironment

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Cell Biology of Cancer Invasion: 2nd Edition

edited by

Hideki Yamaguchi

submission deadline 15 Jan 2026 | 2 articles | Viewed by 3276 | Submission Open

Keywords: invasion; metastasis; intravasation; extravasation; invadopodia; tumor microenvironment; epithelial– mesenchymal transition; cell migration; cytoskeleton; cell adhesion; extracellular matrix; matrix metalloprotease; cancer-associated fibroblast; tumor-associated macrophage

(This special issue belongs to the Section Cancer Metastasis)

Circulating Tumour DNA and Liquid Biopsy in Oncology

edited by

Yafeng Ma

and Kevin Spring

submission deadline 15 Jan 2026 | 3 articles | Viewed by 2849 | Submission Open

Keywords: cell-free DNA; circulating tumour DNA; liquid biopsy; mutation status; tumour mutational burden; methylation detection; fragmentomics; minimal residual disease; early detection

(This special issue belongs to the Section Cancer Biomarkers)

Displaying special issue 51-100 on page 2 of 25.

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