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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Long-Read Sequencing in Cancer (2nd Edition)

edited by

Luca Ermini

and Patrick Driguez

submission deadline 30 Jun 2026 | Viewed by 99 | Submission Open

Keywords: long-read sequencing; cancer genetics; genomics; transcriptomics; methylomics; cancer research

(This special issue belongs to the Section Molecular Cancer Biology)

Prostate Cancer Pathology and Grade

edited by

Stefano Marletta

and

Giuseppe Fanelli

submission deadline 30 Jun 2026 | Viewed by 99 | Submission Open

Keywords: prostate cancer; Gleason grading; molecular pathology; artificial intelligence; digital pathology; multimodal algorithms

(This special issue belongs to the Section Cancer Pathophysiology)

CDK4/6 Inhibitors in Cancer: Efficacy, Resistance, and Combination Approaches

edited by

Boshi Wang

submission deadline 30 Jun 2026 | Viewed by 88 | Submission Open

Keywords: CDK4/6 inhibitors; palbociclib; abemaciclib; ribociclib; cancer; senescence; combinatorial therapy; prognosis; molecular mechanisms

(This special issue belongs to the Section Cancer Therapy)

Tumor Heterogeneity in Breast Cancer—the “Omics” Revolution

edited by

Angeliki Magklara

and

Spyros Foutadakis

submission deadline 30 Jun 2026 | Viewed by 86 | Submission Open

Keywords: breast cancer; tumor heterogeneity; tumor microenvironment; transcriptional regulation; single-cell RNA-seq; spatial transcriptomics; genomics; epigenomics; proteomics; metabolomics

(This special issue belongs to the Section Molecular Cancer Biology)

Molecular Mechanisms of Cancer Progression and Metastasis

edited by

Babak Behnam

submission deadline 30 Jun 2026 | Viewed by 85 | Submission Open

Keywords: metastasis; molecular mechanisms; tumor microenvironment (TME); epithelial-to-mesenchymal transition (EMT); cancer stem cell; therapeutic strategies; immune evasion

(This special issue belongs to the Section Cancer Metastasis)

Ras-Directed Therapies: A Revolution

edited by

Naiara Perurena

submission deadline 30 Jun 2026 | Viewed by 82 | Submission Open

Keywords: Ras-driven cancers; Ras inhibitors; Ras degraders; Ras signaling; mechanisms of resistance; combination therapies

(This special issue belongs to the Section Cancer Therapy)

Progress in Targeted Nanotherapeutic Delivery Systems for Cancer Precision Medicine

edited by

Linlin Zhang

and Dhananjay Suresh

submission deadline 30 Jun 2026 | Viewed by 77 | Submission Open

Keywords: cancer therapy; drug delivery; tumor targeting; nanotechnology; precision medicine; immunotherapy; new approach methodologies (NAMs)

(This special issue belongs to the Section Methods and Technologies Development)

Radiation Therapy for Metastatic Cancer

edited by Johnny Kao

submission deadline 30 Jun 2026 | Viewed by 74 | Submission Open

Keywords: metastasis; radiation therapy; tumor agnostic; oligometastases; survivorship; combined modality therapy

(This special issue belongs to the Section Cancer Therapy)

Magnetic Resonance in Cancer Research (2nd Edition)

edited by Qiuhong He and Marie-France Vidaver

submission deadline 30 Jun 2026 | Viewed by 71 | Submission Open

Keywords: magnetic resonance; cancer; MRI; MRS; MRSI; NMR; DWI; MR; molecular imaging

(This special issue belongs to the Section Methods and Technologies Development)

Symptom Burden in Cancer: Assessment and Management: 2nd Edition

edited by Sam M. Salek,

Esther Natalie Oliva

and Tatyana Ionova

submission deadline 30 Jun 2026 | Viewed by 67 | Submission Open

Keywords: symptom burden; patient-reported outcomes; symptom assessment; symptom management; cancer survivorship; quality of life

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Immunotherapy for Acute Lymphoblastic Leukemia: Novel Strategies and Clinical Perspectives

edited by Paola Minetto and

Francesco Grimaldi

submission deadline 30 Jun 2026 | Viewed by 67 | Submission Open

Keywords: immunotherapy; CAR T-cell therapy; bispecific antibodies; antibody– drug conjugates; treatment resistance; clinical perspectives; clinical trial in ALL

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Emerging Opportunities in Radiation Oncology: AI, Radiomics, and Particle Therapy Breakthroughs

edited by

Antonio Pontoriero

and

Sara Lillo

submission deadline 30 Jun 2026 | Viewed by 64 | Submission Open

Keywords: radiotherapy; artificial intelligence; radiomics; machine learning; adaptive planning; proton therapy; hadron therapy; precision oncology; particle radiotherapy; clinical outcomes

Fertility and Pregnancy in Cancer

edited by

Bettina Böttcher

submission deadline 30 Jun 2026 | Viewed by 50 | Submission Open

Keywords: cancer; gonadotoxic treatment; pregnancy; offspring; long term survivorship; fertility preservation

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Living with Cancer as a Chronic Disease: Quality of Life and Supportive Care

edited by

Paolo Cotogni

submission deadline 30 Jun 2026 | Viewed by 34 | Submission Open

Keywords: long-term symptom management; palliative care; awareness; coping strategies; survivorship; caregiver; multidisciplinary care coordination

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Diagnostic and Pathological Markers in Human Cancer

edited by

Zuoren Yu

Shengqiong Deng

and Qian Zhao

submission deadline 30 Jun 2026 | Viewed by 27 | Submission Open

Keywords: cancer; biomarker; early diagnosis; pathological markers; prognostic model

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Autophagy and Apoptosis in Cancer Progression

edited by Antonio Ieni

submission deadline 30 Jun 2026 | Viewed by 25 | Submission Open

Keywords: autophagy; apoptosis; cancer progression; cell death pathways; therapeutic resistance

(This special issue belongs to the Section Molecular Cancer Biology)

Breast Cancer Evolution—Insights from Single-Cell Genomics

edited by

Cynthia Ma

submission deadline 30 Jun 2026 | Viewed by 24 | Submission Open

Keywords: single-cell genomics; tumor evolution; intratumoral heterogeneity; lineage plasticity; therapy resistance; spatial transcriptomics; tumor microenvironment; clonal dynamics; multi-omics profiling

(This special issue belongs to the Section Molecular Cancer Biology)

Molecular Insights into Drug Resistance in Cancer: 2nd Edition

edited by Yuqi Yang

submission deadline 30 Jun 2026 | Viewed by 24 | Submission Open

Keywords: drug resistance; cancer treatment; molecular mechanism; chemotherapeutic therapy; small molecules; biologics/large molecules; leukemia; solid tumor

Cellular Immunotherapy for Leukemias—Advances, Limitations, and the Path Forward

edited by Lohith Gowda and Stuart E. Seropian

submission deadline 30 Jun 2026 | Viewed by 20 | Submission Open

Keywords: cellular therapy; cellular immunotherapy; leukemias

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Advances in Treatment of Bladder Cancer

edited by

Murat Akand

and

Guglielmo Mantica

submission deadline 30 Jun 2026 | Viewed by 20 | Submission Open

Keywords: bladder cancer; diagnostic biomarkers; genomics; therapeutic approaches

(This special issue belongs to the Section Cancer Therapy)

Advances and Challenges in Head and Neck Cancer

edited by

Marc Oliva

, Leonor Abreu Ribeiro and Claúdia Vieira

submission deadline 30 Jun 2026 | Viewed by 14 | Submission Open

Keywords: head and neck cancer; biomarkers; immunotherapy; radiosensitizers; multiple tumors

Actual Aspects of Prostate Cancer Treatment—an Interdisciplinary Approach (Third Edition)

edited by

Hans Christiansen

submission deadline 30 Jun 2026 | Viewed by 11 | Submission Open

Keywords: prostate cancer; surgery; radiotherapy; hypofractionation; interdisciplinarity; nuclear medicine; PSMA

(This special issue belongs to the Section Cancer Therapy)

Tumor Microenvironment (TME): Cellular and Molecular Interactions

edited by

Mauricio Retamal

submission deadline 30 Jun 2026 | Viewed by 11 | Submission Open

Keywords: cancer stem cells; hypoxia; connexins; tumor microenvironment; extracellular ATP; immune cells; extracellular acidification; extracellular matrix; extracellular vesicles

(This special issue belongs to the Section Tumor Microenvironment)

New Implication in the Platelet–Cancer Interplay

edited by Lenard M. Lichtenberger

submission deadline 30 Jun 2026 | Viewed by 10 | Submission Open

Keywords: platelet; COX-1; aspirin; phosphatidylcholine; colorectal cancer; thrombocytosis

Advances in Dermoscopy for Melanoma and Non-Melanoma Skin Cancer

edited by

Clay J. Cockerell

, Warren Chan, Jade Conway and

Iman Ali

submission deadline 30 Jun 2026 | Viewed by 8 | Submission Open

Keywords: dermoscopy; skin cancer; diagnosis; artificial intelligence; multimodal imaging; teledermoscopy

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Novel Insights into Mechanisms of Cancer-Associated Thrombosis: 2nd Edition

edited by Tom A J Mckinnon

submission deadline 30 Jun 2026 | Viewed by 8 | Submission Open

Keywords: cancer; thrombosis; venous; arterial

(This special issue belongs to the Section Molecular Cancer Biology)

Tumor Immune Microenvironment: Molecular Mechanism and Signaling Pathway

edited by Hua Tian

submission deadline 30 Jun 2026 | Submission Open

Keywords: tumor immune microenvironment; signaling pathways; immunotherapy; crosstalk

Advances in Therapeutic Strategies for Prostate Cancer

edited by Angelo Naselli and

Giacomo Maria Pirola

submission deadline 1 Jul 2026 | 5 articles | Viewed by 22133 | Submission Open

Keywords: immunotherapy; radiation therapy; hormone therapy; targeted therapies

(This special issue belongs to the Section Cancer Therapy)

Pediatric Brain Tumors: Symptoms, Diagnosis and Treatments

edited by Christian Ott and Julius Höhne

submission deadline 1 Jul 2026 | 3 articles | Viewed by 8188 | Submission Open

Keywords: MRI/CT scans; radiation therapy; chemotherapy; combined therapy

(This special issue belongs to the Section Cancer Therapy)

The Role of Radiotherapy, Immunotherapy and New Surgical Techniques in the Treatment of Lung Neoplasms

edited by

Elisa Meacci

submission deadline 1 Jul 2026 | 3 articles | Viewed by 7522 | Submission Open

Keywords: radiotherapy; immunotherapy; new surgical techniques; lung cancer

(This special issue belongs to the Section Cancer Therapy)

The Mediastinum—Pandora’s Box

edited by

Cesar A. Moran

submission deadline 1 Jul 2026 | Viewed by 556 | Submission Open

Keywords: mediastinum; thymus; imaging; surgery; thymoma; germ cell tumors

Clinical Trials for Diffuse Large B-Cell Lymphomas (DLBCL)

edited by

Erel Joffe

submission deadline 1 Jul 2026 | Viewed by 331 | Submission Open

Keywords: DLBCL; immunotherapy; drug combinations; elderly patients; ctDNA; biomarkers; radiotherapy; clinical trial management; artificial intelligence

(This special issue belongs to the Section Clinical Research of Cancer)

Advancing CAR-T Cell Therapy: The Next Evolution in Breast Cancer Treatment

edited by

Nethaji Muniraj

and

Arun Dharmarajan

submission deadline 1 Jul 2026 | Viewed by 187 | Submission Open

Keywords: CAR-T cell therapy; breast cancer; triple-negative breast cancer (TNBC); HER2-positive breast cancer; tumor microenvironment; immunotherapy

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

The Role of Opioid Therapy for Cancers

edited by Brian Le and

Aaron K. Wong

submission deadline 1 Jul 2026 | Viewed by 50 | Submission Open

Keywords: opioids; palliative care; chronic cancer pain

(This special issue belongs to the Section Cancer Therapy)

Metals in Cancer: From Molecular Mechanisms to Innovative Therapeutics

edited by

Katarina Zivancevic

submission deadline 5 Jul 2026 | Viewed by 77 | Submission Open

Keywords: essential and toxic metals; metal-induced carcinogenesis; metal homeostasis; metallotherapeutics; oxidative stress; tumor microenvironment; immune modulation; metabolic reprogramming; therapy resistance; drug delivery systems

(This special issue belongs to the Section Molecular Cancer Biology)

Microfluidic Technology in Cancer

edited by

Lanju Mei

and

Diganta Dutta

submission deadline 5 Jul 2026 | Viewed by 67 | Submission Open

Keywords: cancer cells separation; cancer cells isolation; cancer cells treatment; lab-on-a-chip technology; bio microfluidics; biomedical microdevices; biosensors; and detection in microfluidics

(This special issue belongs to the Section Methods and Technologies Development)

Perioperative Management and Cancer Outcomes (2nd Edition)

edited by

Daniela Ionescu

submission deadline 9 Jul 2026 | Viewed by 137 | Submission Open

Keywords: perioperative management; cancer treatment outcomes; onco-anesthesiology; preoperative risk assessment; enhanced recovery after surgery (ERAS); pain management; personalized medicine

(This special issue belongs to the Section Cancer Therapy)

Upper Tract Urothelial Carcinoma: Current Knowledge and Perspectives

edited by Katie S. Murray and Saum Ghodoussipour

submission deadline 10 Jul 2026 | 3 articles | Viewed by 7867 | Submission Open

Keywords: upper tract urothelial carcinoma; upper tract disease; urothelial cell carcinoma

(This special issue belongs to the Section Cancer Therapy)

Neuroendocrine Neoplasms: Pathogenesis, Diagnostics, and Therapy

edited by

Beata Jabłońska

submission deadline 10 Jul 2026 | 1 articles | Viewed by 6435 | Submission Open

Keywords: neuroendocrine neoplasms; pathogenesis; diagnostics; therapy

(This special issue belongs to the Section Cancer Therapy)

Clinicopathological Study of Gynecologic Cancer (2nd Edition)

edited by

Massimo Origoni

submission deadline 10 Jul 2026 | 1 articles | Viewed by 1217 | Submission Open

Keywords: gynecological oncology; gynecological cancer; female cancer; uterine cancer; ovarian cancer; endometrial cancer; cancerogenesis; cancer biology; cell transformation; cancer pathology; cancer biology

(This special issue belongs to the Section Clinical Research of Cancer)

Preoperative Optimisation in Patients Undergoing Cancer Surgery: 2nd Edition

edited by

Daniel Steffens

and

Cherry Koh

submission deadline 10 Jul 2026 | Viewed by 83 | Submission Open

Keywords: prehabilitation; medical optimization; exercise; nutrition; psychological interventions; surgery; cancer; surgical outcome; preoperative; clinical trials

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Beyond Cancer: Enhancing Quality of Life for Cancer Survivors (Second Edition)

edited by

Jennifer Jones

, Maryam Lustberg and Muna Al-Khaifi

submission deadline 10 Jul 2026 | Viewed by 81 | Submission Open

Keywords: psychosocial oncology; cancer survivorship; long-term effects of cancer; psychoeducational interventions; nnovative care models; continuing education; knowledge translation

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Molecular Biology, Diagnosis and Management of Endometrial Cancer

edited by

Georgios Androutsopoulos

Georgios Michail

and Thomas Vrekoussis

submission deadline 12 Jul 2026 | 4 articles | Viewed by 9248 | Submission Open

Keywords: endometrial cancer; molecular biology; lymph node dissection; sentinel lymph node mapping; sentinel lymph node dissection; surgery; systemic therapy; radiotherapy; fertility preservation; molecular targeted therapies

(This special issue belongs to the Section Molecular Cancer Biology)

The Role of Flow Cytometry in Hematologic Malignancies

edited by

Kristy Wolniak

and Lucy Fu

submission deadline 12 Jul 2026 | Viewed by 222 | Submission Open

Keywords: flow cytometry; hematology; oncology; malignancy; lymphoma; leukemia; pathology; innovation; methodology; diagnosis

(This special issue belongs to the Section Methods and Technologies Development)

Advances in Hodgkin Lymphoma (HL)

edited by

Antonino Carbone

submission deadline 15 Jul 2026 | 2 articles | Viewed by 3915 | Submission Open

Keywords: classic Hodgkin lymphoma; diagnostic challenges; tumour microenvironment; variability in disease extent; TME-targeted therapies; personalized treatment; relapsed/refractory cHL

(This special issue belongs to the Section Cancer Pathophysiology)

Recent Advances in Liquid Biopsy Biomarkers of Cancer

edited by

Hua-Jun He

submission deadline 15 Jul 2026 | 3 articles | Viewed by 3579 | Submission Open

Keywords: liquid biopsy; circulating tumor cells; circulating tumor DNA; extracellular vesicles; circulating RNA; cfDNA methylation; fragmentome; reference material; miRNA; multi-cancer detection

(This special issue belongs to the Section Cancer Biomarkers)

Advances in Clinical Surgery for Gynecological Cancers

edited by

Sebastian Szubert

submission deadline 15 Jul 2026 | 1 articles | Viewed by 1704 | Submission Open

Keywords: ovarian cancer; endometrial cancer; cervical cancer; gynecological surgery; gynecological oncology; reconstructive surgery; pelvic exenteration; supportive cancer care

(This special issue belongs to the Section Methods and Technologies Development)

Integrating Chemotherapy and Immunotherapy for Head and Neck Cancer

edited by Ken Saijo

submission deadline 15 Jul 2026 | 1 articles | Viewed by 1656 | Submission Open

Keywords: head and neck squamous cell carcinomas; HNSCC; immune checkpoint inhibitor; biomarker; chemotherapy

(This special issue belongs to the Section Cancer Metastasis)

Penile Cancer and Rare Urogenital Malignancies: From Biology to Clinical Management

edited by

Mateusz Czajkowski

and Marcin Matuszewski

submission deadline 15 Jul 2026 | 1 articles | Viewed by 767 | Submission Open

Keywords: penile cancer; urethral carcinoma; upper tract urothelial carcinoma; rare urogenital tumors; surgical management; systemic therapy; epidemiology

Molecular Signatures of Therapy: Biomarkers Predicting Response and Relapse in Cancer

edited by

Antonis Giakountis

submission deadline 15 Jul 2026 | 1 articles | Viewed by 511 | Submission Open

Keywords: molecular biomarkers; therapeutic response; disease relapse; precision oncology; liquid biopsy; predictive biomarkers; multi-omics integration; minimal residual disease; translational oncology

(This special issue belongs to the Section Cancer Biomarkers)

Displaying special issue 851-900 on page 18 of 24.

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