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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Plasma and Cancer Treatment

edited by

Michael Keidar

and

Vikas Soni

submission deadline 30 Jun 2026 | 2 articles | Viewed by 1787 | Submission Open

Keywords: cold atmospheric plasma (CAP); cancer treatment; plasma medicine; reactive oxygen species (ROS); apoptosis; tumor; non-thermal plasma; plasma oncology; cancer and molecular biology; clinical translation; in vivo/preclinical

(This special issue belongs to the Section Cancer Therapy)

Urological Cancer: Epidemiology and Genetics

edited by Ilir Agalliu and Evan Kovac

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1574 | Submission Open

Keywords: environmental factors; lifestyle; genetic susceptibility; biomarkers; prostate cancer; bladder cancer; kidney cancer

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Unveiling the Complexity of Hepato-Biliary-Pancreatic Cancers: From Pathogenesis to Management

edited by

Stefano Cacciatore

and Luiz Zerbini

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1374 | Submission Open

Keywords: hepatocellular carcinoma (HCC); cholangiocarcinoma; pancreatic ductal adenocarcinoma (PDAC); tumour microenvironment; molecular biomarkers; therapeutic resistance; cancer immunotherapy; early cancer detection; precision oncology; targeted therapy

(This special issue belongs to the Section Clinical Research of Cancer)

Genetic Alterations and Features in the Development of Gastrointestinal Cancer

edited by

Alexandra Voutsina

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1371 | Submission Open

Keywords: gastrointestinal cancers; genetic alteration; epigenetic regulation; the mechanism of tumorigenesis; precision treatment

(This special issue belongs to the Section Molecular Cancer Biology)

Surgery in Metastatic Cancer (2nd Edition)

edited by

Ulrich Ronellenfitsch

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1370 | Submission Open

Keywords: metastatic cancer; surgery; metastasectomy; indication; timing

(This special issue belongs to the Section Cancer Therapy)

Neurofibromatosis Type 1 (NF1) Related Tumors (2nd Edition)

edited by

Daochun Sun

and

Sameer Farouk Sait

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1201 | Submission Open

Keywords: NF1; tumorigenesis; cancer stem cells; targeted therapy; tumor microenvironment; epigenetics; case report; metastasis; clinical trials

(This special issue belongs to the Section Tumor Microenvironment)

PARP Inhibitors in Cancer Therapy

edited by

Jie Jiang

and

Fu Gui

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1152 | Submission Open

Keywords: PARP inhibitors; cancer therapy; DNA damage repair; drug discovery

(This special issue belongs to the Section Cancer Therapy)

Targeted Radiotracers for Molecular Imaging and Therapy in Cancer

edited by

Vladimir Tolmachev

and

Maryam Oroujeni

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1111 | Submission Open

Keywords: theranostic; radionuclide molecular imaging; targeted therapy; specificity; selectivity; personalized medicine; radiopharmaceuticals

(This special issue belongs to the Section Methods and Technologies Development)

Recent Advances in Epidemiology of Childhood Cancer

edited by Rafael Peris-Bonet,

Rebeca Ramis

and Adela Cañete

submission deadline 30 Jun 2026 | 2 articles | Viewed by 938 | Submission Open

Keywords: childhood cancer epidemiology; childhood cancer registries; environmental causes of childhood cancer; genetic epidemiology; molecular epidemiology; survival of children with cancer; quality of life; social determinants and inequalities; information technologies and statistical innovations

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Advances in Radiology for the Detection, Diagnosis, and Management of Breast Cancer

edited by Takouhie Catherine Maldjian and Mary M. Salvatore

submission deadline 30 Jun 2026 | 3 articles | Viewed by 861 | Submission Open

Keywords: breast cancer; radiology; breast imaging; mammography; MRI; ultrasound; AI; radiomics; diagnosis; treatment response; image-guided biopsy

(This special issue belongs to the Section Methods and Technologies Development)

Soft Tissue Sarcomas—New Diagnostic and Therapeutic Perspectives Through Clinical Genomic Profiling

edited by

Ewa Koscielniak

and

Monika Sparber-Sauer

submission deadline 30 Jun 2026 | 1 articles | Viewed by 795 | Submission Open

Keywords: soft tissue sarcoma; molecular profiling; cancer genomics; personalized medicine

(This special issue belongs to the Section Cancer Therapy)

Pleural Mesothelioma: From Diagnosis to Treatment

edited by

Giovanni Luca Ceresoli

and

Paolo Andrea Zucali

submission deadline 30 Jun 2026 | 1 articles | Viewed by 674 | Submission Open

Keywords: pleural mesothelioma; histological classification; molecular characteristics; immunotherapy; chemotherapy; radiotherapy; surgery; targeted therapy; emerging therapies

(This special issue belongs to the Section Cancer Therapy)

Radiation Therapy in Oncology

edited by Jerzy Wydmański

submission deadline 30 Jun 2026 | 1 articles | Viewed by 537 | Submission Open

Keywords: radiotherapy; radiation injury; systemic therapy; immunotherapy; cancer; concurrent chemoradiotherapy; stereotactic radiotherapy

(This special issue belongs to the Section Cancer Therapy)

Understanding the Molecular Basis and Immunobiology of Renal Cell Carcinoma and Exploring Novel Therapeutic Strategies

edited by

Heba Khella

submission deadline 30 Jun 2026 | 1 articles | Viewed by 453 | Submission Open

Keywords: renal cell carcinoma; molecular basis; immunobiology; tumor microenvironment; immunotherapy; targeted therapy; metastasis; precision medicine; biomarkers; non-coding RNA; miRNA; prognosis; molecular diagnostics; translational research

(This special issue belongs to the Section Cancer Therapy)

Advanced Segmentation in Multimodal Nuclear Imaging of Solid Tumors and Lymphomas: Tools, Challenges, and Clinical Integration

edited by

Ken Kudura

and Robert Förster

submission deadline 30 Jun 2026 | 1 articles | Viewed by 419 | Submission Open

Keywords: multimodal nuclear imaging; artificial intelligence in nuclear medicine; radiomics in nuclear medicine; tumor segmentation; segmentation techniques; segmentation tools; outcome prediction; radioligand therapy

(This special issue belongs to the Section Methods and Technologies Development)

Surgical Perspectives in Lung Cancer: From Technique to Outcome

edited by Takahiro Homma and Hyun Koo Kim

submission deadline 30 Jun 2026 | Viewed by 410 | Submission Open

Keywords: minimally invasive surgery; enhanced recovery after surgery (ERAS); uniportal VATS; robotic-assisted thoracic surgery (RATS); surgical education; perioperative management; energy devices; lung cancer surgery

(This special issue belongs to the Section Cancer Therapy)

Recent Updates on Treatment of Uveal Melanoma

edited by Richard D. Carvajal, Shaheer Khan and Brian Peter Marr

submission deadline 30 Jun 2026 | Viewed by 407 | Submission Open

Keywords: uveal melanoma; systemic therapies; surgical innovations; radiotherapy; genetic and molecular insights; translational research

(This special issue belongs to the Section Cancer Therapy)

Contemporary Management for Gallbladder Cancer: From Diagnosis to Treatment (2nd Edition)

edited by Hiromichi Ito

submission deadline 30 Jun 2026 | Viewed by 378 | Submission Open

Keywords: gallbladder cancer; radical cholecystectomy; adjuvant chemotherapy; neoadjuvant therapy; incidental gallbladder cancer; multidisciplinary management; preoperative staging

(This special issue belongs to the Section Cancer Therapy)

Innovative Treatments Based on Genomic Aberrations in Leukemia and Lymphoma

edited by

Vera Ulrike Bacher

and

Ashwini K. Yenamandra

submission deadline 30 Jun 2026 | Viewed by 358 | Submission Open

Keywords: leukemia; lymphoma; AI and predictive modeling; MRD; B-ALL; DLBCL; genomics; treatment

(This special issue belongs to the Section Cancer Therapy)

Cancer Inhibitory Receptors: Targeting Tumor Microenvironment Therapeutically

edited by

Vaishali Aggarwal

and Alok Kumar

submission deadline 30 Jun 2026 | Viewed by 325 | Submission Open

Keywords: immune checkpoint inhibitors; immunotherapy; tumor microenvironment; inhibitory receptors; immune system; T cells; malignant cells; therapeutic targets

(This special issue belongs to the Section Cancer Therapy)

Non-Coding RNAs and Extracellular Vesicles in Cancer Crosstalk: Diagnostic and Therapeutic Implications 2nd Edition

edited by

Simona Taverna

and

Giuseppe Cammarata

submission deadline 30 Jun 2026 | Viewed by 320 | Submission Open

Keywords: extracellular vesicles; exosomes; cancer; inflammation; non-coding RNA; microRNAs; circular-RNAs; PIWI-RNAs; lnc-RNAs

(This special issue belongs to the Section Cancer Therapy)

Role of BCL-2 Family Proteins in Cancer: Therapeutic Advancements and Challenges

edited by Sajid Khan

submission deadline 30 Jun 2026 | Viewed by 312 | Submission Open

Keywords: BCL-2 family proteins; apoptosis; BH3 mimetics; thrombocytopenia; proteolysis-targeting chimeras; drug resistance; combination therapy; targeted drug delivery

(This special issue belongs to the Section Cancer Therapy)

Proton and Light Ion Therapy for Cancer

edited by Oliver Jäkel

submission deadline 30 Jun 2026 | Viewed by 300 | Submission Open

Keywords: novel beam delivery concepts; image guidance; adaptive therapy; in vivo monitoring; radiobiological studies with protons and light ions; clinical studies; outcome reports

(This special issue belongs to the Section Cancer Therapy)

Signaling Networks Controlling Ovarian Cancer Progression and Response to Therapy

edited by

Luca Tamagnone

and Roberta Mastrantonio

submission deadline 30 Jun 2026 | Viewed by 292 | Submission Open

Keywords: ovarian cancer; patient-derived models; mesothelium; ascites; immunotherapy; chemotherapy; drug resistance; metastasis; peritoneum; p53; BRCA; signaling pathway; metabolism

(This special issue belongs to the Section Tumor Microenvironment)

Advances in Neoadjuvant Therapy for Urologic Cancer

edited by Carlo Messina

submission deadline 30 Jun 2026 | Viewed by 281 | Submission Open

Keywords: neoadjuvant treatment; bladder cancer; prostate cancer; renal cell carcinoma; penile cancers; immunotherapy; antibody– drug conjugates

(This special issue belongs to the Section Cancer Therapy)

Optimizing Surgical Procedures and Enhancing Outcomes in the Management of Gastrointestinal Cancer

edited by Tim Strate and

Jonas Herzberg

submission deadline 30 Jun 2026 | Viewed by 278 | Submission Open

Keywords: gastrointestinal malignancies; surgical oncology; postoperative outcome; quality of life; anastomotic leakage; anastomotic technique; HIPEC; PIPAC

(This special issue belongs to the Section Cancer Therapy)

Cancer Disparities and Health Equity: Challenges, Insights, and Transformative Strategies

edited by

Mandi Pratt-Chapman

and Jane Ussher

submission deadline 30 Jun 2026 | Viewed by 254 | Submission Open

Keywords: scientific censorship; terminated grants; identity politics and health; LGBTQI+ cancer health equity; LGBTQI+ cancer survivorship and care

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Circadian Rhythms, Cancers and Chronotherapy (2nd Edition)

edited by

Francis Levi

Pasquale F. Innominato

and Esra Tasali

submission deadline 30 Jun 2026 | Viewed by 206 | Submission Open

Keywords: drug development and chronotherapy; chemotherapy; immunotherapy; targeted agents; radiotherapy; surgery; circadian host or tumor biomarkers; electronic patient-reported outcomes; circadian rhythms and sleep; sex- and age specificities; clinical trial designs; mathematical models and artificial intelligence; digital healthcare; telemedicine and logistics

(This special issue belongs to the Section Cancer Therapy)

The Extracellular Matrix and Tissue Engineering: Roles in the Tumor Microenvironment and Implications for Cancer Treatment

edited by

Maria Georgiadou

Eirini Velliou

and

Eugenia Roupakia

submission deadline 30 Jun 2026 | Viewed by 199 | Submission Open

Keywords: extracellular matrix remodeling; stiffness; cancer progression; tumor metastasis; tissue engineering; 3D models; anti-cancer therapies

(This special issue belongs to the Section Cancer Therapy)

Advances in Pancreatic Cancer: Exploring Biomarkers and Prognostic Predictors

edited by

Makoto Abue

submission deadline 30 Jun 2026 | 1 articles | Viewed by 182 | Submission Open

Keywords: pancreatic cancer; biomarkers; diagnosis; prognosis; liquid biopsy; proteomics; metabolomics; tumor microenvironment; genetic aberrations/mutations; inflammatory markers

(This special issue belongs to the Section Cancer Biomarkers)

Hepatocellular Carcinoma: Clinical Evidence and Emerging Therapeutic Benefits

edited by

Alessandro Loglio

submission deadline 30 Jun 2026 | Viewed by 157 | Submission Open

Keywords: artificial intelligence; downstaging; immunotherapy; multidisciplinary approaches; risk factors; nutrition

(This special issue belongs to the Section Cancer Therapy)

Tumor Microenvironment of Thyroid Carcinoma

edited by

Juan Carlos Jaume

submission deadline 30 Jun 2026 | Viewed by 149 | Submission Open

Keywords: thyroid cancer; tumor immune microenvironment (TIME); double-negative T cells (DN T cells); tumor-associated macrophages (TAMs)

(This special issue belongs to the Section Tumor Microenvironment)

Emerging Therapies for Germ Cell Tumors

edited by

Ratnakar Singh

and Krinio Giannikou

submission deadline 30 Jun 2026 | Viewed by 147 | Submission Open

Keywords: testicular cancer; embryonal carcinoma; germ cell tumors; cisplatin; immunotherapy; epigenetics; microRNA; chemoresistance; animal models; targeted therapy

(This special issue belongs to the Section Cancer Therapy)

Updates on Anti-Cancer Drug Research

edited by

Ana Luísa De Sousa-Coelho

and Mónica Fernandes

submission deadline 30 Jun 2026 | Viewed by 145 | Submission Open

Keywords: anti-cancer drug research; drug resistance; biomarkers; pharmacogenomics; single-cell RNA sequencing; non-coding RNAs; multi-omics data

(This special issue belongs to the Section Cancer Drug Development)

A New Road for Cancer Drug Discovery

edited by

Navnath S. Gavande

and

Yubin Ge

submission deadline 30 Jun 2026 | Viewed by 143 | Submission Open

Keywords: cancer drug discovery; artificial intelligence in drug discovery and development; targeted therapy; precision oncology; targeted protein degrades; small-molecule therapeutics; immuno-oncology; undruggable targets; drug resistance mechanisms; combination therapy

(This special issue belongs to the Section Cancer Drug Development)

Human Carcinogens—New Insights from Occupational Exposure

edited by

Enrico Oddone

and

Roberta Pernetti

submission deadline 30 Jun 2026 | Viewed by 139 | Submission Open

Keywords: occupational carcinogens; chemical exposure; cancer prevention; artificial intelligence (AI); workplace health policy

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Basic and Translational Science in Ocular Oncology

edited by Anthony B. Daniels,

Arun D. Singh

and

Jens Folke Kiilgaard

submission deadline 30 Jun 2026 | Viewed by 137 | Submission Open

Keywords: ocular oncology; eye cancer; tumors; melanoma; retinoblastoma; hemangioma; hemangioblastoma; lymphoma

(This special issue belongs to the Section Cancer Pathophysiology)

Arginine and Cancers: Molecular Mechanisms and Anticancer Therapy

edited by

Maria Francesca Baietti

submission deadline 30 Jun 2026 | Viewed by 136 | Submission Open

Keywords: arginine; cancer; therapy; immunotherapy; metabolism

(This special issue belongs to the Section Cancer Drug Development)

Genomics and Genetics in Brain Cancer Treatment, Diagonals, and Prognosis

edited by

Nan Hu

submission deadline 30 Jun 2026 | Viewed by 128 | Submission Open

Keywords: genomics; genetics; brain tumor; brain cancer; glioblastoma multiform; glioma; cancer diagnosis; cancer prognosis

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Myeloma and Immunology

edited by

Cristina João

submission deadline 30 Jun 2026 | Viewed by 126 | Submission Open

Keywords: multiple myeloma; tumor immunology; immune microenvironment; immunotherapy; CAR-T cells; immune evasion; immune profiling

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Evolving Management of Gastroesophageal Cancers: From Local Therapies to Precision Oncology

edited by

Ilyas Sahin

submission deadline 30 Jun 2026 | Viewed by 123 | Submission Open

Keywords: gastric cancer; esophageal cancer; immunotherapy targeted therapy; radiation therapy; surgical oncology; precision oncology; molecular biomarkers; multimodal treatment

(This special issue belongs to the Section Cancer Therapy)

Redox Balance, Antioxidant Defenses, and Inflammation in Cancer: From Initial Changes to Tumor Progression

edited by Andrej Veljković,

Gordana Kocic

and

Aleksandra Klisic

submission deadline 30 Jun 2026 | Viewed by 123 | Submission Open

Keywords: oxidative stress; inflammation; cancer progression; pre-malignant changes; biomarkers; tumor microenvironment; cell signaling; therapeutic targets

(This special issue belongs to the Section Tumor Microenvironment)

Pharmacokinetics in Cancer Treatment

edited by Jing Li

submission deadline 30 Jun 2026 | Viewed by 122 | Submission Open

Keywords: pharmacokinetics (PK); pharmacodynamics (PD); population PK/PD modeling; PBPK modeling; clinical pharmacology; personalized oncology; cancer treatment; pharmacogenetics; molecular pharmacology

(This special issue belongs to the Section Cancer Drug Development)

Clinical Application of Proton Therapy and Advanced Radiotherapy in Gynecological Cancer

edited by Amy Tien Yee Chang and

Bin Yang

submission deadline 30 Jun 2026 | Viewed by 121 | Submission Open

Keywords: proton therapy; cervical cancer; endometrial cancer; vaginal cancer; MR-guided radiotherapy; MR-guided brachytherapy; stereotactic body radiotherapy

(This special issue belongs to the Section Cancer Therapy)

Advances in Clinical Treatment of Pancreatic Cancers

edited by

Alberto Brolese

submission deadline 30 Jun 2026 | Viewed by 118 | Submission Open

Keywords: pancreatic cancer; PDAC; neoadjuvant chemotherapy; neuroendocrine tumors; pNET; pancreatic cystic disease; IPMN; pancreatic oligometastases

(This special issue belongs to the Section Clinical Research of Cancer)

Contemporary Thoracic Cancer Surgery: Technology and Innovation

edited by

Yoshikane Yamauchi

submission deadline 30 Jun 2026 | Viewed by 112 | Submission Open

Keywords: thoracic cancer surgery; robotic-assisted thoracic oncology procedures; video-assisted thoracoscopic surgery for thoracic malignancies; thoracic neoplasms; minimally invasive surgery in cancer treatment; surgical outcomes; lung cancer surgery; surgical innovation in thoracic oncology

(This special issue belongs to the Section Methods and Technologies Development)

Research and Treatment of Hepatocellular Carcinoma

edited by Chung Cheung Thomas Yau

submission deadline 30 Jun 2026 | Viewed by 110 | Submission Open

Keywords: hepatobiliary cancer; biomarker; immunotherapy; targeted therapy; combination treatments

(This special issue belongs to the Section Cancer Therapy)

Immunotherapy Approaches in Breast Cancer Treatment (2nd Edition)

edited by Yi Huang and

Bing Li

submission deadline 30 Jun 2026 | Viewed by 109 | Submission Open

Keywords: breast cancer progression; immunotherapy; combination therapy; drug discovery; antitumor immunity; tumor immune microenvironment; biomarkers and clinical trials

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Advances in Targeted Therapies and Pharmacogenomics of Leukemia

edited by

Nicolas Nassar

submission deadline 30 Jun 2026 | Viewed by 106 | Submission Open

Keywords: blood cancer; targeted therapy; immunotherapy; primary and secondary resistance; pharmacogenetics; combination therapy; tumor microenvironment

(This special issue belongs to the Section Molecular Cancer Biology)

Nanocarriers in Cancer Therapy

edited by

Wenyi Gu

submission deadline 30 Jun 2026 | Viewed by 104 | Submission Open

Keywords: nanoparticles; cancer therapy; anticancer drug delivery

(This special issue belongs to the Section Methods and Technologies Development)

Displaying special issue 801-850 on page 17 of 24.

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