Towards Precision Medicine: From Biomarker Discovery to Novel Therapeutic Target Candidates for Human Cancers

Dear Colleagues,

The discovery and development of novel biomarkers and therapeutic targets have greatly accelerated progress towards precision medicine in oncology. Multi-platforms for molecular characterization of tumors have given rise to new efforts in performing pathological, biochemical, molecular, and immunological research to study the mechanisms underlying carcinogenesis, with the final aim of finding the cancer biomarkers and molecular targets, which could be applied in clinical practice. Cancer biomarkers are of great interest for early diagnosis, prognosis, and prediction of treatment response and may aid in the development of new anti-cancer targeted therapies with proven benefits for treatment response and survival. However, plenty of research opportunity exists for discovering, developing, and validating cancer biomarkers and targets for improving the clinical outcomes of patients with malignant diseases. The present Special Issue aims to collect the most relevant research in the emerging areas of clinical molecular diagnostics, drug development, and targeting different signaling pathways involved in tumorigenesis.

Dr. Silvia Zappavigna
Dr. Marianna Abate
Dr. Marco Bocchetti
Guest Editors

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