Computational Approaches for Multi-Omics and Biomedical Data Analysis in Cancer Research

Dear Colleagues,

Cancer remains one of the most complex and challenging diseases to treat, characterized by immense genomic and phenotypic heterogeneity. In recent years, the rapid growth of various data, including genomic, transcriptomic (especially single-cell RNA sequencing and spatial profiling), metabolomic, proteomic and imaging, have profoundly supported oncology research. To effectively analyze and interpret these vast datasets in cancer research, the application of advanced computational approaches has become essential.

This Special Issue, “Computational Approaches for Multi-Omics and Biomedical Data Analysis in Cancer Research,” aims to highlight the latest advancements in bioinformatics, machine learning and artificial intelligence (including foundation models) as applied to clinical and translational oncology. We particularly welcome studies that develop or apply computational methods for integrating multiple molecular and biomedical data modalities to improve our understanding of cancer biology, tumor heterogeneity and disease progression.

We invite original research articles and comprehensive reviews that explore the development and implementation of novel computational tools for cancer biomarker discovery, medical imaging, multi-omics analyses for personalized medicine and tumor microenvironment analysis. By bridging the gap between computer science and cancer biology through the analysis of diverse molecular and imaging data, this collection will provide valuable insights into disease mechanisms and pave the way for next-generation, data-driven therapies.

Dr. Joanna Żyła
Dr. Michal Marczyk
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.